Patents Examined by Andrew E Hoffpauir
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Patent number: 12648706Abstract: The present disclosure provides a steerable and adjustable recorder pulse pillow for Traditional Chinese Medicine pulse diagnosis, and relates to the technical field of recorder pulse pillows. The steerable and adjustable recorder pulse pillow for Traditional Chinese Medicine pulse diagnosis comprises a main body, wherein a platform is installed right above the main body. The top surface of the platform is installed with a recording device. The bottom of the recording device is provided with a rotary disc. The rear end surface of the recording device is provided with an operating button. The rotary disc is fixedly connected with a micro-motor driving wheel inside the recording device. The micro-motor is electrically connected with a rotary knob of the recording device.Type: GrantFiled: March 22, 2023Date of Patent: June 9, 2026Assignee: Institute of Information on Traditional Chinese Medicine, China Academy of Chinese of Medical SciencesInventors: Jie Yang, Baoyan Liu, Tiancai Wen, Bin Wang, Lei Zhang
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Patent number: 12593987Abstract: There is provided a forehead temperature measurement system including an image sensor, a thermal sensor and a processor. The image sensor is used to output an image frame. The thermal sensor is used to output a thermal image. The processor is used to determine a forehead region in the image frame, map the forehead region to the thermal image and identify a forehead temperature according to a forehead mapped region in the thermal image. The processor further calibrates or compensates the forehead temperature according to an area of the forehead region.Type: GrantFiled: July 26, 2021Date of Patent: April 7, 2026Assignee: PIXART IMAGING INC.Inventors: Po-Wei Yu, Yi-Chung Chen, Ting-Yang Chang, Chih-Ming Sun, Kai-Shun Chen, Yen-Chang Chu
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Patent number: 12575766Abstract: A non-invasive diagnostic system is disclosed that integrates Raman spectroscopy with Artificial Intelligence (AI) to detect, classify, and quantify biomarkers and pharmacologic agents in the aqueous humor of the anterior chamber of the eye. The system includes a handheld or slit lamp-mounted Raman probe, a spectral acquisition and preprocessing pipeline, and an AI analysis engine trained to recognize disease-associated molecular signatures. The platform supports real-time diagnosis of glaucoma, uveitis, and other anterior segment conditions, enabling early detection, risk stratification, and longitudinal monitoring. The AI component is capable of incorporating newly discovered biomarkers and contextual factors such as medication use, diurnal variation, and anatomical sampling location. Diagnostic outputs are presented with confidence scores and may include disease classification, biomarker trends, or pharmacologic exposure levels. Built-in safety protocols ensure ANSI Z136.Type: GrantFiled: May 9, 2025Date of Patent: March 17, 2026Inventor: Michael Reynard
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Patent number: 12564423Abstract: Systems and methods are provided for accessing a renal capsule of a patient's kidney in a minimally invasive manner for therapeutic and/or diagnostic purposes. The method includes advancing the distal end of a catheter into the subcapsular space of the renal capsule and performing the therapeutic and/or diagnostic procedure(s). With access to the renal capsule, the catheter may be used to, for example, remove fluid from the subscapular space, decapsulate the renal capsule by disrupting the fibrous capsule of the renal capsule to relieve renal pressure, displace the fibrous capsule from the kidney, measure/monitor renal pressure within the kidney, and/or deliver drug therapy and/or stem cells, viruses for gene therapy, RNAi, nanoparticles, dyes, etc. to the subcapsular space of the renal capsule.Type: GrantFiled: May 12, 2020Date of Patent: March 3, 2026Assignee: Tufts Medical Center, Inc.Inventors: Navin K. Kapur, Richard H. Karas
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Patent number: 12533043Abstract: A device (10) processes and visualizes EIT data (3) of at least one region of the lungs to determine and visualize ventilation delays in the lungs of a living being. The EIT data (3) are obtained from an electrical impedance tomography apparatus (30). The device makes it possible to visualize regional ventilation delays of the lungs or of regions of the lungs in which the delay exceeds a predefined duration (76) in a joint image (900).Type: GrantFiled: May 31, 2024Date of Patent: January 27, 2026Assignee: DRÄGERWERK AG & CO. KGAAInventor: Yvo Gärber
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Patent number: 12521023Abstract: A temperature self-compensation interventional optical fiber pressure guidewire includes: a first guidewire section, a second guidewire section, and a third guidewire section that are arranged in sequence and are hollow, and a fiber bragg grating (FBG)-Fabry-Perot (FP) cascaded optical fiber sensor. The first guidewire section is configured to guide the second guidewire section and the third guidewire section in a blood vessel; the second guidewire section and the third guidewire section are internally hollow and are communicated to each other. The FBG-FP cascaded optical fiber sensor is arranged inside the second guidewire section and extends towards an inside of the third guidewire section. The FBG-FP cascaded optical fiber sensor is configured to simultaneously measure a temperature signal and a pressure signal inside the blood vessel. The present invention is particularly applicable to measuring parameters of a region before and after stenosis inside the blood vessel.Type: GrantFiled: April 10, 2025Date of Patent: January 13, 2026Assignee: Wuhan University of TechnologyInventors: Tianliang Li, Jianglin Zhu, Tao Huang, Haotian Zhou, Zichun Cao
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Patent number: 12502514Abstract: A vascular access device adapter allowing for interchangeable connections between separate components of a larger extravascular system while minimizing exposure to non-sterile environments in point-of-care testing and analysis is provided. The vascular access device adapter includes a body having a self-healing puncturable septum secured by an end cap by which hollow small gauge needles may extract or deposit fluid. The adapter device further includes an end cap enclosing the septum, the end cap having ribs which removably secure the adapter to the inner housing of a sample collection device.Type: GrantFiled: August 26, 2020Date of Patent: December 23, 2025Assignee: Becton, Dickinson and CompanyInventors: Bo Yan, Yueqiang Xue, Xiwei Chen, Jonathan Karl Burkholz
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Patent number: 12490903Abstract: A dermal imaging system coordinates operation of an illumination unit, one or more lenses, and a camera to capture a sequence of images of an area of interest on a skin surface. The system automatically tags each image in the sequence of images. The tag for each image identifies a light source, an illumination angle, and a filter selected for capturing the image. The system automatically selects at least one image from the sequence of images, and analyzes the selected image from the sequence of images to provide a recommended skin disease diagnosis.Type: GrantFiled: July 7, 2021Date of Patent: December 9, 2025Assignee: Welch Allyn, Inc.Inventors: David G. Perkins, Yaolong Lou, Shadakshari D. Chikkanaravangala, Stephen C. Daley, Helmi Kurniawan, Chee Keen Lai, Hon Kuen Leong, Bryan Ng
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Patent number: 12478317Abstract: A method of measuring a biomechanical parameter of soft biological tissue is described. The method includes a pre-measurement process wherein an impulse applying device applies a pre-pressure to a surface of the tissue via an end portion contacting the tissue surface. While maintaining the pre-pressure, the device generates at least two impulses separated by a time interval, each impulse causing the end portion to impart to the tissue an action with certain parameters, each action inducing a response of the tissue. A value of a biomechanical parameter of the tissue is determined from each response induced. A determination is made as to whether the determined values of the biomechanical parameter are sufficiently similar to each other to indicate that the pre-pressure, the parameters of the end portion actions and the time interval are acceptable for use in a measurement process to be conducted on the surface of the tissue.Type: GrantFiled: March 23, 2020Date of Patent: November 25, 2025Assignees: VANDERBILT UNIVERSITY, UNIVERSITY OF TARTUInventors: Arved Vain, Eric Tkaczyk, Mihkel Pöldemaa
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Patent number: 12465215Abstract: A system utilizing five or less body worn sensors may be used to profile the motor function of Parkinson's disease patients, integrate the outcome with patient self-reported information and translate the results to clinically relevant information, valuable for the monitoring of Parkinson's disease progression and symptom manifestation. The hardware of the system may deploy algorithms for the offline processing of the sensors' data, once the wearable monitoring devices are docked for charging, with no intervention required by the user. The system may also allow patients to mount the wearable devices featuring the sensors to any of a limited number of body parts, without taking care to mount each monitoring device to a specific body part. Finally, the system may allow a physician to register for a subscription-based service, pairing him/her with patients using the system, and granting him/her permission to remotely review the disease progression of the patients, as calculated by the system.Type: GrantFiled: December 14, 2018Date of Patent: November 11, 2025Assignee: PD NEUROTECHNOLOGY LTDInventor: Dimitrios Fotiadis
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Patent number: 12453540Abstract: A portable digital rectosigmoidoscope single-handed, digital intestinal endoscope, used by suitably trained healthcare workers to digitally view the anus, rectum and distal sigmoid colon in people with anorectal symptoms at point of care.Type: GrantFiled: October 10, 2019Date of Patent: October 28, 2025Assignee: Surgease Innovations LimitedInventors: Fareed Iqbal, Gillian Gole-Cruz, Robin Crossley, Jeremy Gardner
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Patent number: 12408851Abstract: Wireless electrochemical measurements methods using minimally invasive micro-sensors that monitor response of cells to specific analytes are described. Micro-actuators integrated on a same chip as the micro-sensors are used to provide closed loop in-vivo local therapy on demand. An in-vivo bio-electronic system that can monitor the health of cell colonies and accordingly dispense corresponding therapeutic drugs is also described.Type: GrantFiled: September 29, 2020Date of Patent: September 9, 2025Assignees: CALIFORNIA INSTITUTE OF TECHNOLOGY, THE TRUSTEES OF DARTMOUTH COLLEGEInventors: Axel Scherer, Arti Gaur
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Patent number: 12383198Abstract: A finger clip type oximetry device adaptive to thick and thin fingers comprises a housing, an upper finger pad, a lower finger pad, a light emitting device and a receiver provided and a rotating mechanism. Wall surfaces of the upper and lower finger pads enclose an accommodating cavity. An opening is formed in one end of the accommodating cavity. An arc-shaped first contact surface is provided in an area of the lower finger pad in the accommodating cavity in contact with the pulp of the finger, and an arc-shaped second contact surface is provided in an area of the upper finger pad in the accommodating cavity in contact with the finger back. A first concave surface and second concave surfaces are provided along a transverse direction of the finger. The bending degree of the first concave surface is greater than that of the second concave surfaces.Type: GrantFiled: May 13, 2019Date of Patent: August 12, 2025Assignee: Shenzhen Narig Bio-Medical Technology Co., Ltd.Inventors: Jin Fang, Xiaocui Zhang
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Patent number: 12383144Abstract: An optical analysis of saliva or a fluid-saliva mix obtained during or after an oral care action is performed in order to check whether the saliva or fluid-saliva mix contains blood, which allows for determining whether or not a person may suffer from gingivitis or another condition affecting gum health. In particular, light received from a representative sample (23) containing saliva is detected and analyzed. The analysis involves determination of measurement values of light received by a light-receiving unit (25) for one or more main wavelengths of the light and one or more auxiliary wavelengths of the light. Advantageously, the main wavelength(s) is/are associated with high hemoglobin absorption and the auxiliary wavelength(s) is/are associated with low hemoglobin absorption. A measurement value at an auxiliary wavelength is used for correcting a measurement value at as main wavelength for background influences.Type: GrantFiled: August 15, 2019Date of Patent: August 12, 2025Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Olaf Thomas Johan Antonie Vermeulen, Steven Charles Deane, Lucas Petrus Henricus Scheffers
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Patent number: 12376754Abstract: Provided herein are systems, methods and apparatuses for a Biomarker sensor.Type: GrantFiled: August 23, 2021Date of Patent: August 5, 2025Assignee: American University of BeirutInventors: Moussa Bteich, Joseph Costantine, Rouwaida Kanj, Assaad Eid, Youssef Tawk, Ali H. Ramadan
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Patent number: 12357171Abstract: Techniques are disclosed for systems and methods to provide improved ocular aberrometry. An ocular aberrometry system includes a wavefront sensor configured to provide wavefront sensor data associated with an optical target monitored by the ocular aberrometry system and a logic device configured to communicate with the wavefront sensor. The logic device is configured to receive ocular aberrometry output data including at least the wavefront sensor data provided by the wavefront sensor, determine estimated ocular alignment deviations corresponding to a relative position and/or orientation of the optical target monitored by the ocular aberrometry system based, at least in part, on the received ocular aberrometry output data, and generate user feedback corresponding to the received ocular aberrometry output data based, at least in part, on the estimated ocular alignment deviations.Type: GrantFiled: September 25, 2020Date of Patent: July 15, 2025Assignee: Alcon Inc.Inventors: Max Hall, Thomas Padrick, Edwin Jay Sarver
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Patent number: 12347099Abstract: An apparatus for obtaining images for use in determining one or more properties of skin of a subject, the apparatus comprising an image sensor unit for generating an image of a skin sample, wherein the skin sample corresponds to an area of skin of the subject within a field of view, FOV, of the image sensor unit when the skin of the subject is spaced a predetermined working distance from the image sensor unit; a first light arrangement comprising one or more light sources for illuminating the skin of the subject; and a second light arrangement comprising one or more light sources for illuminating the skin of the subject.Type: GrantFiled: February 26, 2019Date of Patent: July 1, 2025Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Arnoldus Johannes Martinus Jozeph Ras, Walter Hermans, Willem Auke Westerhof, Babu Varghese, Willem Minkes, Sahil Wadhwa, Martijn Van Zutphen
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Patent number: 12336806Abstract: A breath sampler for collecting a breath sample from a patient is disclosed. The breath sampler has a non-rebreather part including a sample inlet, a one-way outlet valve downstream of the sample inlet, and an air inlet. The one-way outlet valve and the sample inlet define a first portion of an internal breath flow pathway therebetween. The air inlet is arranged to be closed by a one-way inlet valve arranged to allow air to enter the non-rebreather part. The breath sampler also has a sample delivery part in fluid communication with the non-rebreather part at an upstream end via the one-way outlet valve. The sample delivery part defines a second portion of the internal breath flow pathway, and has an air diverter, a sample outlet, a return inlet and a sample collection chamber connector.Type: GrantFiled: September 13, 2019Date of Patent: June 24, 2025Assignee: Stichting Radboud universitair medisch centrumInventors: Marinus Isaäk de Jonge, Cornelis Hubertus van den Kieboom, Michèl Mathijs Klerks, Ronald van Doorn
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Patent number: 12336795Abstract: A device for non-invasive venous-pressure sensing comprises an occlusive element (OC) configured to be applied to a proximal portion of a human limb in order to apply an occlusion pressure thereto, and a dilation-sensing element (VS) configured to be applied to a distal portion of a human limb in order to detect an extent of dilation thereof. The device likewise comprises a control circuit (10) coupled to the occlusive element (OC) and to the dilation-sensing element (VS).Type: GrantFiled: May 28, 2020Date of Patent: June 24, 2025Assignee: TRE ESSE Progettazione Biomedica S.r.l.Inventor: Gianni Plicchi
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Patent number: 12329513Abstract: An eye sensor, system and method for measuring fixational eye movements of an individual's eyeball (e.g., ocular microtremors and microsaccades) to provide a variable voltage biosignal for measuring the individual's brain stem activity. The eye sensor comprises a sensor mounted on the individual's closed or opened eyelid so as to be deflected by the fixational eye movements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the sensor to an amplifier located on the individual's skin where the biosignal is amplified. The amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician. A method for analyzing the biosignal to determine the brainstem activity of a patient.Type: GrantFiled: December 7, 2020Date of Patent: June 17, 2025Inventors: Michael Baltay, Clark B. Foster, Ciaran Bolger, Martin Acquadro, Bruce A. Rasmussen