Patents Examined by Andrew S Rosenthal
  • Patent number: 11123279
    Abstract: The present invention relates to cosmetic or personal care compositions comprising two or more compounds, each compound containing an allylic or partially allylic carbonylsubstructure having the following structure I: wherein Y is a second substructure immediately adjacent to the allylic or partially allyliccarbonyl substructure and is selected from one of the following groups consisting of (i) hydroxyl-based group including —OH or —C(?)—(OH); (ii)carbonyl-based group including —C(?)—C (?O)—CH3; (iii) N ether group, —O—; (iv) sultam group, —N(H)—S(?O)2—; (v) lactam group, —N(H)—C(?O)—; (vi) apolar group including cyclic structures based on menthol or carotenoids; (vii) secondary aldimine containing group including —N(H)—C(NH2)?N— or —N(H)—C(H)?N—; (viii) amine group, —NH2; (ix) secondary amine-based group, —N(H)—; and (x) amide-based group including —N(H)—C(?O)— or —N(H)—C(?O)—N(H)—, their derivatives, isomers, salts and/or combination thereof; and a cosmetically acceptable vehicle.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: September 21, 2021
    Assignee: AchromaZ Pte. Ltd.
    Inventors: Peter Samuel James Cheetham, Christoph Langwallner, Margit Langwallner, Wen Jue Amelia Tan
  • Patent number: 11123298
    Abstract: Provided herein in some embodiments are pharmaceutical compositions comprising a prostacyclin (PGI2) receptor agonist selected from 2-(((1r,4r)-4-(((4-chlorophenyl)(phenyl)carbamoyloxy)methyl)cyclohexyl)methoxy)acetic acid (Compound 1) and pharmaceutically acceptable salts, solvates, and hydrates thereof, as disclosed herein. In some embodiments the pharmaceutical compositions comprise a compound selected from 2-(((1r,4r)-4-(((4-chlorophenyl)(phenyl)carbamoyloxy)methyl)cyclohexyl)methoxy)acetic acid (Compound 1), and pharmaceutically acceptable salts, solvates, and hydrates thereof, in an amount equivalent to a therapeutically effective amount of Compound 1, the composition having a release rate by weight of the compound in an aqueous medium that is one or more of release rates (a), (b) and (c) as disclosed herein. The compositions of the present invention are useful in the treatment of PGI2 related disorders, such as those disclosed herein.
    Type: Grant
    Filed: April 16, 2019
    Date of Patent: September 21, 2021
    Assignee: ARENA PHARMACEUTICALS, INC.
    Inventors: Zezhi Jesse Shao, Raizza Berania Florida, Ching-Yuan Li, Lee Alani Selvey
  • Patent number: 11111362
    Abstract: Films for medical devices and/or packaging include polyethylene-poly(ethylene oxide) amphiphilic graft copolymers (PE-g-PEO) in their base polymer formulations of polyethylene and poly(ethylene oxide). The films may be treated to include a nitric-oxide releasing agent incorporated into the PE-g-PEO. Also, microbial agents for inclusion in medical devices are provided, which comprise: an olefin-poly(ethylene oxide) amphiphilic graft copolymer, wherein a portion of the poly(ethylene oxide) comprises end groups converted to a nitric oxide-releasing agent. The amphiphilic graft copolymer of the microbial agents may comprise a polyethylene-poly(ethylene oxide) amphiphilic graft copolymer (PE-g-PEO), a polypropylene-poly(ethylene oxide) amphiphilic graft copolymer (PP-g-PEO), or mixtures thereof.
    Type: Grant
    Filed: September 21, 2017
    Date of Patent: September 7, 2021
    Assignee: Becton, Dickinson and Company
    Inventors: Jianbin Zhang, Theresa Hermel-Davidock, Edward Bryan Coughlin
  • Patent number: 11110066
    Abstract: An implantable delivery device and method for utilizing the device to delivery a bioactive agent to a subject in need thereof is described. The device includes a pattern of structures fabricated on a surface of the device to form a nanotopography. A random or non-random pattern of structures may be fabricated such as a complex pattern including structures of differing sizes and/or shapes. The device may be located adjacent tissue such as an endovascular implant or a perivascular implant, and may deliver the bioactive agent without triggering an immune or foreign body response to the bioactive agent.
    Type: Grant
    Filed: October 16, 2012
    Date of Patent: September 7, 2021
    Assignee: SORRENTO THERAPEUTICS, INC.
    Inventors: Jeremy Ollerenshaw, Emily Reichart, Russell F. Ross
  • Patent number: 11103432
    Abstract: This invention relates to a topical, cosmetic or dermatological composition, comprising a 1,3 diglyceride having the general formula (I), in which the radicals R1 and R2 represent, independently of one another, a C13 to C40 saturated and linear alkyl radical, and at least one cosmetic or dermatological excipient for a topical application on the skin. This invention also relates to such a composition, or a 1,3 diglyceride having the formula (I), for its use in protecting the skin, in countering the weakening of the skin barrier and in preventing or reducing the penetration of exogenous molecules into the skin following a weakening of the skin barrier.
    Type: Grant
    Filed: April 8, 2020
    Date of Patent: August 31, 2021
    Assignee: PIERRE FABRE DERMO-COSMETIQUE
    Inventors: Daniel Redoules, Gwendal Josse
  • Patent number: 11083760
    Abstract: A formulated oral prebiotic edible composition useful for promoting a desired oral microbiota to treat a respiratory allergic condition and/or an oral and/or sinus infection condition in a subject in need of such treatment, the oral prebiotic including comprising L-arginine, the L-arginine including free individual molecules of L-arginine, the free individual molecules of L-arginine L present at a concentration of greater than about 0.1 wt %; a carrier, and a sugar comprising at least one of a monosaccharide and disaccharide; the composition in a configuration suitable to be maintained including being substantially dissolved within the oral cavity for over a period of at least about 1 minute to about an hour, the composition in an effective amount to thereby selectively promote an increased concentration of oral microbiota to thereby treat the respiratory and/or oral and/or sinus related allergy condition, the selected oral microbiota including Veillonella and Streptococcus.
    Type: Grant
    Filed: July 23, 2019
    Date of Patent: August 10, 2021
    Assignee: Knoze Jr. Corporation
    Inventor: Shunsheng Han
  • Patent number: 11083675
    Abstract: The disclosure relates to compositions for treating keratinous substrates, such as the hair, comprising monoethanolamine and at least one carboxylic acid, as well as systems and methods for treating keratinous substrates with the compositions.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: August 10, 2021
    Assignee: L'OREAL
    Inventors: Kimberly Dreher, Gérard Provot, Dariusz Danielski, Fabien Boulineau, Caroline Rahmouna Francoise Goget, Anthony Potin, Allison Chin, Michael DeGeorge, Mara Applebaum, Mary Abraam Soliman, Ashley Ann Figatner, Megan Pauker, Emmanuel Appiah-Amponsah
  • Patent number: 11083759
    Abstract: A method of selectively promoting a desired oral microbiota to treat an inflammation condition associated with an allergic reaction in a subject in need of such treatment including providing a composition including: at least one live bacterial population including lactic acid producing bacteria and lactic acid fermenting bacteria; and, an amino acid containing ingredient comprising L-arginine; at least partially removing a biofilm within an oral cavity of the subject; wherein the composition is contained within the oral cavity of the subject in an effective amount to selectively promote an increased concentration of selected oral microbiota comprising the lactic acid producing bacteria and the lactic acid fermenting bacteria to thereby treat the inflammation condition.
    Type: Grant
    Filed: July 8, 2019
    Date of Patent: August 10, 2021
    Assignee: Knoze Jr. Corporation
    Inventor: Shunsheng Han
  • Patent number: 11065344
    Abstract: Embodiments of the present disclosure describe a conjugate comprising a mesoporous nanoparticle having a plurality of pores, wherein the mesoporous nanoparticle is positively charged, wherein an active agent is disposed in the pore; and a plurality of metal nanoclusters, wherein the metal nanocluster has a negative charge, wherein a gate agent is attached to the metal nanocluster. Embodiments of the present disclosure also describe a method of using a conjugate comprising exposing a conjugate to microbes sufficient to release an active agent and treating the microbes with the released active agent. Embodiments of the present disclosure further describe a method of using a conjugate comprising exposing a conjugate to microbes and detecting a presence of the microbes.
    Type: Grant
    Filed: October 2, 2017
    Date of Patent: July 20, 2021
    Assignee: KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Shahad Alsaiari, Mohamed Amen Hammami, Niveen M. Khashab
  • Patent number: 11065368
    Abstract: The present invention provides, in certain aspects, medical graft products that incorporate multiple drug depots in and/or on the products. One such product is a sheet graft construct, for example for tissue support that includes a sheet graft material with a plurality of drug depots. The drug depots can be hardened deposits formed directly onto the sheet graft material and/or can be capable of eluting a drug for a minimum of 72 hours.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: July 20, 2021
    Assignees: Cook Biotech Incorporated, Cook Medical Technologies LLC
    Inventors: Rhonda Peck, Bhavin Shah, Umesh H. Patel, Krista Gearhart, Steven Charlebois, Keith Milner, Eric J. Rodenberg
  • Patent number: 11058112
    Abstract: This application relates to compositions for cleaning and disinfecting unclean surfaces that are contaminated, typically with bacteria, viruses, yeast and molds. Broadly speaking contaminated surfaces includes hard and soft surfaces such as those found in household environments, in industrial environments, and hospitals, as well as surfaces of food products such as fruits, vegetables and meat. Further, the compositions can be prepared with naturally occurring components that are classified as generally considered as safe (GRAS) by the US FDA and/or comply with National Organic Production (NOP) standards of the USDA and can therefore be used in situations where such a classification is required such as organic food production.
    Type: Grant
    Filed: August 17, 2019
    Date of Patent: July 13, 2021
    Assignee: Maria Beug-Deeb, Inc.
    Inventors: Maria U. D. Beug-Deeb, Thomas M. Deeb
  • Patent number: 11058774
    Abstract: The present invention provides methods for facilitating cleansing of the gastrointestinal tract of a patient prior to a diagnostic, surgical or therapeutic procedure. The methods can improve patient compliance, and thus, efficacy of the preparation. Specifically, the present methods make the gastrointestinal tract preparation composition palatable for the patient to consume. For example, for a patient preparing to undergo colonoscopy, the present methods make the bowel preparation solution taste significantly less salty.
    Type: Grant
    Filed: April 25, 2019
    Date of Patent: July 13, 2021
    Assignee: MSM Innovations, Inc.
    Inventors: Steven Gorelick, Michael Schiffman, Melody Olmstead, Adam Gorelick
  • Patent number: 11051515
    Abstract: The invention relates to 3-acyl-benzamides of formula (I) as herbicides. In formulae (I) X, Y, Z and Rx represent radicals such as alkyl, cycloalkyl and halogen.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: July 6, 2021
    Assignee: Bayer Aktiengesellschaft
    Inventors: Christian Waldraff, Arnim Koehn, Hartmut Ahrens, Ralf Braun, Hansjoerg Dietrich, Anu Bheemaiah Machettira, Christopher Hugh Rosinger, Elmar Gatzweiler, Elisabeth Asmus
  • Patent number: 11051826
    Abstract: Described herein are compositions comprising, a polymer; a non-physiological solution; and a visualization agent; wherein the polymer is soluble in the non-physiological solution and insoluble at physiological conditions. Methods of preparing the compositions are disclosed as well as methods of using these compositions to treat vascular conditions.
    Type: Grant
    Filed: June 17, 2019
    Date of Patent: July 6, 2021
    Assignee: MicroVention, Inc.
    Inventors: Aaron Baldwin, Ami Mehta, Jonathan Lam
  • Patent number: 11045493
    Abstract: Provided, inter alia, are synthetic melanin nanoparticles (MelNPs) useful for protecting keratinocytes from UV-damage and for treating melanin-defective diseases.
    Type: Grant
    Filed: July 11, 2017
    Date of Patent: June 29, 2021
    Assignee: The Regents of the University of California
    Inventors: Nathan C. Gianneschi, Yuran Huang, Yiwen Li
  • Patent number: 11040224
    Abstract: Provided is a water-in-oil cosmetic composition comprising one or more thickening agents selected from the group consisting of sodium polyacrylate starch, polyacrylate crosspolymer-6, xanthan gum and locust bean gum in an inner phase. The water-in-oil cosmetic composition of the present invention brings improvements to time-related changes in preparation stability by means of inner phase thickening controlling the flow properties of an aqueous phase, and controls the size of emulsified particles by means of inner phase thickening, and as a result the invention has outstanding thixotropic characteristics and outstanding initial spreadability and has outstanding durability and, in addition, the invention provides both a fresh-cream-like soft feel in use and a liquid-like light feel in use.
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: June 22, 2021
    Assignee: AMOREPACIFIC CORPORATION
    Inventors: Kyung Nam Kim, Kyung Ho Choi, Yeong Jin Choi
  • Patent number: 11040112
    Abstract: Compounds are provided having the following structure: or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1, R2, R3, L1, L2, G1, G2 and G3 are as defined herein. Use of the compounds as a component of lipid nanoparticle formulations for delivery of a therapeutic agent, compositions comprising the compounds and methods for their use and preparation are also provided.
    Type: Grant
    Filed: November 8, 2018
    Date of Patent: June 22, 2021
    Assignee: ACUITAS THERAPEUTICS, INC.
    Inventors: Steven M. Ansell, Xinyao Du
  • Patent number: 11040045
    Abstract: This invention relates to the use of the combination of 25-hydroxyvitamin D3 (“25-OH D3”) and antioxidants/anti-inflammatories (ascorbic acid, vitamin E and at least one carotenoid) to make a pharmaceutical, nutraceutical or food supplement which can ameliorate various problems observed in humans connected with polycystic ovarian syndrome and cardiovascular diseases. Pharmaceuticals, nutraceuticals and food supplements containing the 25-OH D3 and antioxidants/anti-inflammatories and premixes are also provided.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: June 22, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Shuen Ei Chen, Thau Kiong Chung, Daniel Raederstorff, Wolfgang Schalch
  • Patent number: 11033521
    Abstract: There is provided a convenient new treatment of Parkinson disease by a frequent administration of optimal levodopa doses mimicking a continuous intravenous or infusion treatment, thus mitigating motor complications; and a new carbidopa/levodopa pharmaceutical unit form providing said new treatment.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: June 15, 2021
    Assignee: AVION PHARMACEUTICALS, LLC
    Inventors: Thomas N Chase, Kathleen E. Clarence-Smith
  • Patent number: 11027049
    Abstract: Embodiments of the invention include bioactive agent eluting devices. In an embodiment the invention includes a bioactive agent delivery device including a substrate, a hydrophilic polymer disposed on the substrate, and a substantially amorphous bioactive agent disposed on the surface of the hydrophilic polymer. In an embodiment, the invention includes a method of making a bioactive agent delivery device including depositing a hydrophilic polymer on a substrate forming a hydrophilic surface and depositing a substantially amorphous bioactive agent on the hydrophilic surface. In an embodiment, the invention includes a bioactive agent-eluting catheter including a catheter shaft and an expandable balloon disposed on the catheter shaft. Other embodiments are included herein.
    Type: Grant
    Filed: May 31, 2018
    Date of Patent: June 8, 2021
    Assignee: Surmodics, Inc.
    Inventors: Ralph A. Chappa, Andrew G. Bach