Patents Examined by Andrew Wans
  • Nucleozymes
    Patent number: 6140491
    Abstract: Nucleozymes containing ribonucleotides and deoxyribonucleotides or nucleic acid analogues are described herein. The nucleozymes have catalytic activity and are significantly more resistant to degradation than their all-RNA ribozyme counterparts. Also described are methods for preparing the nucleozymes along with methods of using nucleozymes, e.g., as therapeutic agents.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: October 31, 2000
    Assignee: Ribozyme Pharmaceuticals, Inc.
    Inventors: Nassim Usman, Alexander Rich, Robert J. Cedergren, Jean-Pierre Perreault, Jing-Hua Yang