Patents Examined by Angela D. Sykes
  • Patent number: 7912540
    Abstract: An article of clothing is provided for selectively destroying dividing cells in living tissue formed of dividing cells and non-dividing cells. The dividing cells contain polarizable intracellular members and during late anaphase or telophase, the dividing cells are connected to one another by a cleavage furrow. The article of clothing includes insulated electrodes to be coupled to a generator for subjecting the living tissue to electric field conditions sufficient to cause movement of the polarizable intracellular members toward the cleavage furrow in response to a non-homogeneous electric field being induced in the dividing cells. The non-homogeneous electric field produces an increased density electric field in the region of the cleavage furrow. The movement of the polarizable intracellular intracellular members towards the cleavage furrow causes the breakdown thereof which adversely impacts the multiplication of the dividing cells.
    Type: Grant
    Filed: June 14, 2006
    Date of Patent: March 22, 2011
    Assignee: Standen Ltd.
    Inventor: Yoram Palti
  • Patent number: 7664546
    Abstract: A posture detection system includes an implantable device and a patient-external respiratory therapy device coupled via a communications channel. At least one of the implantable device and the patient-external respiratory therapy devices includes a posture detector. Posture information is transferred between the implantable device and the patient-external respiratory therapy device. The posture information may be used in connection with sleep detection or to modify therapy delivered by the implantable cardiac device and/or the patient-external respiratory therapy device.
    Type: Grant
    Filed: September 15, 2004
    Date of Patent: February 16, 2010
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Jesse W. Hartley, Jeffrey E. Stahmann, Kent Lee, Quan Ni
  • Patent number: 7660632
    Abstract: A method of treating sleep disordered breathing in a patient includes the steps of monitoring the patient for a pre-inspiratory drive signal indicative of the breathing cycle by sensing electroneurogram activity of a hypoglossal nerve of the patient; and electrically stimulating the hypoglossal nerve of the patient following each detection of the pre-inspiratory drive signal. An implantable apparatus for stimulating a hypoglossal nerve of a patient for the treatment of sleep disordered breathing includes an electrode positioned at least partially around the hypoglossal nerve with a monitoring contact and a stimulation contact and a controller operatively coupled to the monitoring contact and the stimulation contact. The monitoring contact monitors the electroneurogram activity of the hypoglossal nerve for a pre-inspiratory drive signal indicative of the onset of inspiration and sends a signal to the controller which in turn causes the stimulating electrode to electrically stimulate the hypoglossal nerve.
    Type: Grant
    Filed: June 28, 2007
    Date of Patent: February 9, 2010
    Assignee: RIC Investments, LLC
    Inventors: Todd Kirby, Erik K. Witt
  • Patent number: 7650187
    Abstract: An assembly for wireless energy communication to an implanted device comprises an external belt (7) accommodating a wearer control (1) followed by controller (2), a battery pack (4), an inverter (3), a transmission coil (8) connected in parallel by a plurality of capacitors, and an infrared transceiver 9. Provided furthermore is an implanted device comprising a receiver coil (11) having the same dimensions as the transmission coil (8), a rectifier following said receiver coil (11), an infrared transceiver (10) followed by a controller and an sensor assembly (17) assigned thereto as well as a battery pack (16) for powering said implanted device via an energy manager (14).
    Type: Grant
    Filed: November 17, 2004
    Date of Patent: January 19, 2010
    Assignee: Deutsches Zentrum für Luft-und Raumfahrt e.V.
    Inventors: Robin Gruber, Thomas Schmid
  • Patent number: 7650184
    Abstract: An implantable lead includes a tubular polymer body having a plurality of wire conductors embedded or carried within the inner tube body. A ring contact, e.g., a platinum ring contact, is electrically and mechanically connected to at least one of the plurality of wires at at least one end of the tubular body. In one embodiment, ring contacts are attached at both ends of the tubular body. In another embodiment, a lumen passes longitudinally through the length of the lead body.
    Type: Grant
    Filed: November 30, 2006
    Date of Patent: January 19, 2010
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventor: Jeryle L. Walter
  • Patent number: 7647108
    Abstract: Methods and systems involve selecting lead configurations in a pulse generator capture verification system. Capture threshold data is collected from at least one alternative electrode configuration. The capture threshold data from the at least one alternative electrode configuration is compared with capture threshold data collected using a primary electrode configuration. A pacing electrode configuration is selected based on the comparison. Backup safety pacing is provided using the primary electrode configuration.
    Type: Grant
    Filed: September 30, 2004
    Date of Patent: January 12, 2010
    Assignee: Cardiac Pacemakers, Inc.
    Inventor: Scott M. Freeberg
  • Patent number: 7647106
    Abstract: It has been discovered that a change in posture that results in an increase in orthostatic stress, when followed by a withdrawal of sympathetic nervous activity, may indicate a future onset of vasovagal syncope (VVS). The invention is directed to devices and techniques for early detection of an episode of VVS so that therapies may be applied in advance of the episode to prevent the episode from occurring. Detection of a posture transition triggers a device such as an implanted pacemaker to determine an indicator of an autonomic nervous system activity of the patient. As a function of this determination, the device estimates a probability that the patient will experience VVS. When the probability exceeds a threshold, preventative therapy may be applied to address the VVS and to reduce the risk that the patient will faint.
    Type: Grant
    Filed: April 23, 2003
    Date of Patent: January 12, 2010
    Assignee: Medtronic, Inc.
    Inventors: Nathalie Virag, Rolf Vetter, Richard Sutton
  • Patent number: 7647113
    Abstract: In a method of implanting an electrode of an electronic stimulator device into an external urinary sphincter of a male patient, a first incision is made in the perineum of the patient between the anus and the scrotal-perineal junction. A distal end of a stimulation lead is then fed through the first incision, through the perineal membrane and into the external urinary sphincter. The distal end includes the electrode. In one embodiment of the method, a second incision is made in the abdomen of the patient. In one embodiment, the second incision is made lateral to and cephalad to the pubis bone of the patient. Next, a proximal end of the stimulation lead is fed from the first incision to the second incision. In one embodiment, the proximal end of the stimulation lead is coupled to a control unit of the electronic stimulator device. Electrical signals are generated using the control unit and the electrical signals are delivered to the external urinary sphincter through the stimulation lead and the electrode.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: January 12, 2010
    Assignee: AMS Research Corporation
    Inventors: Alan G. Wirbisky, Andrew P. VanDeWeghe
  • Patent number: 7641635
    Abstract: A method of non-delaminably bonding a non-porous thermoplastic elastomer to a substrate by heating a bilayer of the elastomer and the substrate for a predetermined time and a product obtained by the method. Methods for producing non-delaminable conduits and non-delaminable kink-resistant conduits constructed of biocompatible elastomers and substrates, and products produced by these methods are taught. Methods, products, and articles of manufacture relating to non-delaminable monofilament supported kink-resistive conduits that may be used as inflow conduits in left ventricular assist devices for treatment of heart failure are also provided.
    Type: Grant
    Filed: September 11, 2001
    Date of Patent: January 5, 2010
    Assignee: Edwards Lifesciences Corporation
    Inventors: Donald T. Shannon, Chris Kuo, Benita Tu, Mike Randall
  • Patent number: 7643884
    Abstract: A surgical needle assembly for penetrating soft and hard tissues of a patient includes a handle assembly removably coupled to the needle assembly. The needle assembly is electrically coupled to an electrical signal source. The surgical tool includes an electrically conductive portion in communication with an un-insulated distal end of the needle assembly, and an insulated portion extending from the distal end to the handle assembly.
    Type: Grant
    Filed: January 31, 2005
    Date of Patent: January 5, 2010
    Inventors: John D. Pond, Jr., William Keith Adcox
  • Patent number: 7640054
    Abstract: A method of generating a template in an implantable medical device for implantation within a patient, and a processor readable medium for performing the method, that includes generating a template from collected events corresponding to the patient, delaying the generation of the template for a first predetermined time period in response to the template not being generated within a predetermined number of collected events, determining whether the template is valid, and monitoring the template to determine whether the template is an accurate representation of the patient.
    Type: Grant
    Filed: May 26, 2006
    Date of Patent: December 29, 2009
    Assignee: Medtronic, Inc.
    Inventors: Lev A. Koyrakh, Eugene Davydov, Jeffrey M. Gillberg, Jian Cao
  • Patent number: 7611471
    Abstract: The invention provides a method and apparatus for analysing a heart signal from a beating heart, the method comprising: collecting the heart signal, performing a cluster analysis of the signal to identify the first heart sound and the second heart sound, determining an energy envelope for each of a plurality of regions in the signal, determining the area of each of the energy envelopes, and classifying features in the signal by an analysis incorporating at least the areas, whereby one or more characteristics of the heart can be determined.
    Type: Grant
    Filed: May 28, 2002
    Date of Patent: November 3, 2009
    Assignee: HD Medical Inc.
    Inventor: Arvind Thiagarajan
  • Patent number: 7613520
    Abstract: A system and method for treating auditory dysfunction by somatosensory system stimulation. The system and/or method comprises a probe and a device to stimulate the probe. The probe has a stimulation portion subcutaneously implanted in communication with a predetermined spinal cord site. The stimulation portion of the probe may be implanted externally to the spinal cord, or may be implanted epidurally. The stimulation portion may be a laminotomy, paddle, surgical, or multiple electrode lead. The device to stimulate the probe may also be implanted subcutaneously.
    Type: Grant
    Filed: October 20, 2005
    Date of Patent: November 3, 2009
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventor: Dirk De Ridder
  • Patent number: 7613519
    Abstract: A system and/or method for treating auditory dysfunction by somatosensory system stimulation. The system and/or method comprises a probe and a device to stimulate the probe. The probe has a stimulation portion implanted in communication with a predetermined peripheral nerve site. The stimulation portion of the probe may be implanted in contact with a peripheral nerve dorsal root ganglia, cranial nerve or dermatome area, for example C2 dermatome area or a trigeminal dermatome area. The stimulation portion may be a laminotomy, paddle, surgical, or multiple electrode lead. The device to stimulate the probe may be implanted subcutaneously or transcutaneously.
    Type: Grant
    Filed: October 20, 2005
    Date of Patent: November 3, 2009
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventor: Dirk De Ridder
  • Patent number: 7580745
    Abstract: A cardiac rhythm management system modulates the delivery of pacing and/or autonomic neurostimulation pulses based on heart rate variability (HRV). An HRV parameter being a measure of the HRV is produced to indicate a patient's cardiac condition, based on which the delivery of pacing and/or autonomic neurostimulation pulses is started, stopped, adjusted, or optimized. In one embodiment, the HRV parameter is used to adjust a maximum tracking rate in an atrial tracking pacing mode.
    Type: Grant
    Filed: January 18, 2005
    Date of Patent: August 25, 2009
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Joseph M. Pastore, Rodney W. Salo, Gerrard M. Carlson, Andrew P. Kramer, Jiang Ding, Yinghong Yu
  • Patent number: 7580749
    Abstract: A system is described. The system includes a lithium battery, a charge storage capacitor electrically connected to the lithium battery, a first device, and at least one second device. The first device is electrically connected to the lithium battery and is powered by the lithium battery. The at least one second device is attached to the charge storage capacitor and adapted to read a rate of charge storage in the charge storage capacitor or to calculate the rate of charge storage by measuring both a time of charging and a charge stored or added to the charge storage capacitor during the time of charging.
    Type: Grant
    Filed: July 18, 2007
    Date of Patent: August 25, 2009
    Assignee: Cardiac Pacemakers, Inc.
    Inventor: Michael J. Lyden
  • Patent number: 7574263
    Abstract: A method and apparatus for adjusting a visual image provided to a patient. In one embodiment, an image may be presented to the patient to obtain the patient's subjective perception of the image, and the patient may either manipulate the image to obtain a desired adjustment, or guide a clinician performing the adjustment. In another embodiment, the clinician may make objective observations of, for example, the position of an electrode array on the patient's retina, and make adjustments accordingly. The adjustment may be a spatial adjustment comprising a re-mapping performed to decreases image distortion resulting from differences in the patient's perception of stimulation of different areas of the retina. Such distortion may result from differences between the patient's perception of stimulation falling within the macula, and stimulation falling within the periphery surrounding the macula. The adjustment may also compensate for translations or rotations of the electrode array on the retina.
    Type: Grant
    Filed: January 31, 2003
    Date of Patent: August 11, 2009
    Assignee: Second Sight Medical Products, Inc.
    Inventors: Robert J. Greenberg, Richard Williamson
  • Patent number: 7571003
    Abstract: A device for carrying out a cosmetic method or treating skin ageing and the method comprising the following steps: a) connecting an electronic device, able to generate high frequency electric current waves having a distorted sinusoidal wave form by the presence of harmonics, to one or more electrodes of essentially laminar shape; b) applying said one or more electrodes on the skin surface in the area to be treated; c) activating said electronic device in order to transfer said current waves to said one or more electrodes and to maintain said device activated for a predetermined time; d) deactivating said device and removing the electrodes form the contact with the treated area.
    Type: Grant
    Filed: April 8, 2004
    Date of Patent: August 4, 2009
    Assignee: Telea Electronic Engineering S.r.l.
    Inventor: Gianantonio Pozzato
  • Patent number: 7571011
    Abstract: An implantable electrode and method for manufacturing the electrode wherein the electrode has a strong, adherent surface coating of iridium oxide or titanium nitride on a platinum surface, which demonstrates an increase in surface area of at least five times when compared to smooth platinum of the same geometry. The iridium oxide coating may be formed on platinum by a physical deposition process, such as sputtering. The process of electroplating the iridium oxide surface coating is accomplished by voltage control processes. A gradient coating of iridium oxide ranging in composition from essentially pure platinum to essentially pure iridium oxide is produced by sputtering.
    Type: Grant
    Filed: September 5, 2003
    Date of Patent: August 4, 2009
    Assignee: Second Sight Medical Products, Inc.
    Inventors: Dau Min Zhou, Robert J. Greenberg, Neil H. Talbot
  • Patent number: 7569020
    Abstract: In a method and apparatus for measuring the ejection fraction in a mammalian heart, the opening and closing of a heart valve is sensed with an implanted sensor, and a pre-ejection period is measured as a function of the sensed opening and closing of the heart valve. The ventricular ejection time also is measured, and the ejection fraction is determined as a function of the measured pre-ejection period and the ejection time.
    Type: Grant
    Filed: June 19, 2006
    Date of Patent: August 4, 2009
    Assignee: St. Jude Medical AB
    Inventors: Kjell Norén, Nils Holmström