Abstract: A wearable injection device for subcutaneous injection of a therapeutic agent, wherein the dose is injected over a specified period of time after the device is activated.

Abstract: The present invention relates to an at least partly implantable system for injecting a substance into a patient's body. The system is provided with at least one infusion needle disposed at least partly within at least one housing with a tip end of the at least one infusion needle arranged for penetrating the at least one housing's outer wall, and at least one drive unit adapted for implantation inside the patient's body, the at least one drive unit being coupled to the at least one infusion needle and arranged for advancing and retracting the tip end of the at least one infusion needle so that the at least one infusion needle penetrates, upon advancement of the tip end thereof, said at least one housing's outer wall in at least one penetration area so as to allow for injecting the substance through said at least one penetration area via the at least one infusion needle.

Abstract: An exhaust tool (50) includes: a flexible body portion (51) extending over substantially an entire length of a cylindrical shaft (30, 90) of an incision energy device (e.g., ultrasonic coagulation incision device 10 or electrocautery device 80) having an energy generation portion (32) for incision provided at a tip thereof; a pair of holding portions (52) provided to the body portion (51) and configured to hold the cylindrical shaft (30, 90); and a flow path formation portion (54) forming therein a flow path (56) for mist generated from the energy generation portion (32). The exhaust tool (50) is allowed to be attached/detached to/from the cylindrical shaft (30, 90) by the pair of holding portions (52) being opened through bending of the body portion (51).

Abstract: Disclosed is a guidewire steering micro-robot. The guidewire steering micro-robot includes a guidewire, and a steering unit provided at an end portion of the guidewire, the steering unit including a magnetic body to control and steer a position of the guidewire by an external magnetic field.

Abstract: The present embodiments provide systems and methods suitable for delivering a therapeutic agent to a target site. In one example, the system comprises a container for holding the therapeutic agent, and a pressure source having pressurized fluid, wherein the pressure source is in selective fluid communication with at least a portion of the container. A catheter is placed in fluid communication with the container, and has a lumen sized for delivery of the therapeutic agent to a target site. A housing is configured to securely retain the container. The system further comprises a camera having a camera head coupled to the catheter, wherein the camera provides a visual image of the target site during delivery of the therapeutic agent.

Abstract: Medication delivery devices are provided having a dose delivery sensing capability. A sensed element is attached to a dose setting member of the device. The sensed element includes surface features radially-spaced from one another. A rotational sensor is attached to an actuator of the device. The rotational sensor includes a movable element that is contactable against the surface features. The rotational sensor is configured to generate a signal in response to the movement of the movable element over the surface features during their rotation. A controller is operatively coupled to the rotational sensor, and in response to receiving the generated signal, the controller is configured to determine a number of the surface features passing the movable element of the rotational sensor during dose delivery. The number can be associated with an amount of dose delivered. Sensing can be provided in a module or integrated in device.

Abstract: A fluid pumping system may comprise a pump and a fluid line state detector having, a receptacle, at sensor, and an illuminator. The system may further comprise a fluid transfer set including an output line for mating into the receptacle. The system may further comprise a controller in data communication with the fluid line state detector configured to power the illuminator and monitor an output signal of the sensor when the outlet line is in the receptacle to determine a dry tube light intensity value. The controller may be further configured to govern operation of the pump to prime the output line with fluid. The controller may be further configured to power the illuminator, monitor the output signal, and halt operation of the pump when the output signal indicates the light intensity value has dropped below a primed line threshold which is dependent upon the dry tube intensity value.

Abstract: An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.

Abstract: A transparent tubing is provided comprising a longitudinal axis having a center; an inner circumferential surface defining a fluid pathway therethrough for delivering a first medium having a first index of refraction m; an outer circumferential surface; at least one visual marker; and, at least one integrated lens disposed opposite from the at least one visual marker, the at least one integrated lens configured to direct light from the at least one visual marker for detecting a presence or an absence in the fluid pathway of a second medium having a second index of refraction n2, where n2 is different from the first index of refraction n1. A method of making transparent tubing having at least one integrated lens is also provided.

Abstract: Embodiments of the present invention are directed to the treatment of hypertension, diabetes, obesity, heart failure, end-stage renal disease, digestive disease, urological disease, cancers, tumors, pains, asthma, pulmonary arterial hypertension, and chronic obstructive pulmonary disease by delivering of an effective amount of formulations at desired temperature to target tissue. The formulations include gases, vapors, liquids, solutions, emulsions and suspensions of one or more ingredients. The temperature may enhance safety and efficacy of the formulations for the treatments. The amounts of the formulation and/or energy are effective to injury or damage the tissues to have a benefit of symptom relive.

Abstract: Pre-filled syringes, pharmaceutical compositions, and kits and methods relating to same allow for emergency administration of one or more drugs from prefilled glass syringes to a patient via a needleless connector. In preferred embodiments, the prefilled glass syringe has a drug volume of at least 5 mL, has a Luer-lock, and has a syringe tip with an internal channel that has a diameter of about 1.7 mm. Such syringes advantageously allow storage of emergency drugs without leaching of plastic materials and degradation, and substantially improve the safety profile where the syringe is attached to an IV line via a needleless connector.

Abstract: A surgical humidification system includes a source of gas flow and a humidifier that receives the gas flow and outputs a humidified gas to a delivery conduit. The delivery conduit has an outlet and a suitable interface, such as a diffuser, is connected to the outlet. The interface can be positioned near or within an open surgical cavity of a patient to supply the humidified gas to the cavity. The system also includes a pressure relief arrangement that operates to relieve pressure from the system above a normal operating pressure. The pressure relief arrangement can be located in a non-sterile portion of the system, such as upstream from the humidifier, for example.

Abstract: Disclosed is a safety syringe that comprises a needle sleeve (1), a needle base (3) and a core rod (2). First claws (34) on the needle base (3) are configured to clamp in a first groove (111) on an inner wall of the needle sleeve (1), one of a proximal end of the needle base (3) and a distal end of the core rod (2) is provided with second claws (33), and the other one thereof is provided with a position-limiting member; the second claws (33) are configured to abut against the position-limiting member along a slanted surface.

Abstract: Methods and devices for accurately pumping small quantities of liquid to a patient with a broad range of flow and low cost.

Abstract: Provided is an electrotherapy device suitably used in electroporation method, and specifically configured to inject medicine and the like into deep inside of the body. The electrotherapy device has an outer shaft having a lumen and extending in a distal-proximal direction; an inner shaft disposed in the lumen of the outer shaft; a needle tube fixed to the inner shaft; and at least one linear conductor having at least one electrode needle fixed to the inner shaft and having at least one conductive line connected to a proximal part of the electrode needle, the needle tube and the electrode needle configured to project or retract from a distal part of the outer shaft.

Abstract: An apparatus includes a body, and anchoring feature, and a guide feature. The body is sized and configured to be positioned on an eye of a patient. The anchoring feature is configured to secure the body to the eye of the patient. The guide feature is configured to guide a cannula into a scleral incision formed in the eye of the patient along a path that is substantially tangential relative to the eye of the patient. The guide feature is sized and configured to allow the cannula to pivot laterally through a range of angular motion at the scleral incision.

Abstract: A connector comprises a body having a tubing portion and a luer portion axially opposite the tubing portion and connected thereto, an internal passageway defined by an inner circumferential surface of the connector, the passageway extending axially between the tubing portion and the luer portion and in fluid communication therewith, a stopping mechanism disposed in the luer portion and configured to limit an extent of a fluid line disposed in the connector, and a retaining mechanism disposed in the tubing portion and configured to retain the fluid line in the connector.

Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device to deliver fluid to a user in accordance with an operating mode involves identifying a fluid type associated with the fluid currently onboard the infusion device from among a plurality of possible fluid types that is different from a previous type of fluid previously onboard the infusion device. The identified fluid type has pharmacokinetics characteristics that are different from pharmacokinetics characteristics associated with the previous fluid type. The method continues by updating one or more parameters referenced by a control module of the infusion device implementing the operating mode to reflect the pharmacokinetics characteristics associated with the identified fluid type and autonomously operating the infusion device to deliver the fluid of the identified fluid type to the user in accordance with the operating mode and the one or more updated control parameters.

Abstract: A medication delivery device includes an infusion pump system having a reservoir, a fluid path connected between the reservoir and an insertion mechanism, a plunger arranged inside the reservoir, and a pump drive mechanism coupled with the reservoir. The medication delivery device further includes a processing device configured to determine a user fill volume of a fluid medication by analyzing a location of the plunger inside the reservoir when a fill of the fluid medication is completed. The processing device is configured to determine the user fill volume of the fluid medication by sensing a pressure inside the reservoir.

Abstract: A dosing pump, in particular a microdosing pump, has a pump chamber in which a fluid inlet is provided at a first valve seat and a fluid outlet is provided at a second valve seat. A control element is coupled to an actuator to move the control element in order to vary the pump chamber in terms of volume. The control element is movably mounted by means of a flexure hinge.