Abstract: A system for predicting adoption of a prescribed treatment plan by an individual includes a data repository, a memory storing instruction, and a control system to execute the instructions. The data repository is communicatively coupled to a network and includes a plurality of storage devices storing data. The control system receives at least a portion of the data stored in the data repository. The at least a portion of the data is associated with the individual. The control system uses the machine learning adoption prediction algorithm to process the received at least a portion of the data to determine a likelihood that the individual will adopt the prescribed treatment plan. Based at least in part on (i) the prescribed treatment plan and (ii) the determined likelihood that the individual will adopt the prescribed treatment plan, the control system generates a personalized treatment adoption plan for the individual.

Abstract: Representative methods, apparatus and systems are disclosed for providing concurrent electrical stimulation and electrical recording in a human or non-human subject, such as for neuromodulation, with the apparatus coupleable to an electrode array. A representative apparatus is typically an integrated circuit including: stimulation circuits, recording circuits, and blocking circuits responsive to control signals to block the stimulation voltage or current on an electrode from a corresponding recording circuit, while other recording circuits may simultaneously record electrical signals from other electrodes and generate recorded data.

Abstract: An implantable neurostimulator for delivering one or more stimulation pulses to a target region within a patient's body. The implantable neurostimulator including a housing and an energy storage feature. There is also a lead coupled to the hermetic housing and a plurality of electrodes located proximate to a distal end of the lead. The neurostimulator includes stimulation circuitry that includes an adjustable resistance element. A voltage of the electric signal derived from the energy storage feature and a resistance of the adjustable resistance element are both adjusted based on a measurement of a value indicative of a tissue impedance of the target region to provide a desired value of a stimulation current for the one or more stimulation pulses.

Abstract: An apparatus for delivering tumor treating fields to a subject's body. The apparatus comprises: a plurality of electrically coupled electrode elements to be located on a subject's body and able to deliver tumor treating fields to the subject's body, wherein at least one electrode element of the plurality of electrically coupled electrode elements comprises a dielectric layer, the dielectric layer has a first surface to face the subject's body and a second surface opposite the first surface, and at least one of the first surface and the second surface of the dielectric layer is a non-planar surface.

Abstract: The disclosure provides systems and methods for treating obstructive sleep apnea using an inertial measurement unit (IMU) comprising an accelerometer and a gyroscope, wherein the IMU is configured to detect chest and/or abdominal movement by a patient during the inspiration and expiration stages of a respiratory cycle and to generate positional data based on the detected movement. Positional data generated by the IMU is used by an implanted stimulation system to determine when to deliver electrical stimulation to a nerve which innervates an upper airway muscle, such as the hypoglossal nerve, to treat sleep apnea.

Abstract: The invention provides personalized laser probes for use in laser systems, wherein each laser probe includes one or more characteristics tailored to a given user to thereby improve performance of and outcome of a laser treatment procedure.

Abstract: It is an object to provide a device for estimating a plurality of mental/nervous system diseases by the voice analysis, the device being capable of estimating either major depression or bipolar disorder. Furthermore, there are provided an estimation device including an extraction means for extracting an acoustic feature amount that is not affected by a location where voices are acquired, and a method for operating the estimation device.

Abstract: The lead implanted in a body to apply electrical stimulation to body organs may include: an electrode wire having one end provided as an insertion portion to be inserted into a body and the other end provided as an interface portion for connection with an external device to transmit a stimulation signal: a plurality of first electrodes in the insertion portion; a plurality of second electrodes on the interface portion; and a plurality of signal lines interconnecting the first electrodes and the second electrodes, wherein the insertion portion of the electrode wire includes a plurality of support portions on which the first electrodes are respectively disposed and a plurality of stretchable portions between the support portions and expandable and contractible, and further includes an operation unit for pushing or pulling each support portion in a longitudinal direction of the electrode wire to adjust a position of the support portion.

Abstract: A cardiac assist device with an expandable cup (4) having a transport state and an operational state, the expandable cup comprising a plurality of inflow apertures (5), and an outflow nozzle (6), and an inflatable balloon (8) positioned inside the expandable cup (4). A catheter assembly (3) is connected to the inflatable balloon (8) during operation, and a control unit (2) is connected to the catheter assembly (3). The control unit (2) is arranged to operate the inflatable balloon (8) with a frequency of more than 100 beats per minute.

Abstract: The present technology is generally directed to methods for addressing a patient's sleep apnea. At least some of the methods can include one or more of percutaneously inserting an implantable signal delivery device at an insertion point on the patient's neck, moving the signal delivery device in a medial-to-lateral direction toward an ansa cervicalis nerve of the patient, and implanting the signal delivery device at a target location at least proximate to the ansa cervicalis nerve. The signal delivery device can include at least one electrode positioned to deliver a modulation signal to tissue at least proximate to the target location, such as a portion of the ansa cervicalis nerve. In some embodiments, delivery of the modulation signal can induce caudal traction in the patient and thereby address the patient's sleep apnea.

Abstract: Disclosed is an adjustable cryoablation needle, comprising a needle rod (3), a front-segment heat-insulated tube (1), a rear-segment heat-insulated tube (2), and an gas inlet structure (7) penetrating the needle rod (3) and the front-segment heat-insulated tube (1), wherein the needle rod (3) can move relative to the rear-segment heat-insulated tube (2) in the axial direction of the rear-segment heat-insulated tube (2) so as to adjust a first axial distance between the front end of the rear-segment heat-insulated tube (2) and the front end of the needle rod (3); and the front-segment heat-insulated tube (1) can move relative to the rear-segment heat-insulated tube (2) in the axial direction of the rear-segment heat-insulated tube (2). The adjustable cryoablation needle can prevent the inconvenience caused by a doctor selecting the model of the cryoablation needle.

Abstract: Treatment device for ultrasonic treatment and high frequency treatment procedure is equipped with an ultrasonic transducer including piezoelectric elements converting electrical power into ultrasonic vibrations. The treatment device includes a transmission rod with a treatment probe and jaw for clasping objects. The transmission rod includes one or more features for damping, to minimize or prevent excess vibrations and to, among other things, decrease frictional heat caused by the friction between the damping features and the transmission rod arising from attenuating the ultrasonic vibrations.

Abstract: Described herein are devices and methods for performing ablation using ablation catheters with one or more patterned and textured active areas. An ablation catheter includes a proximal section, a distal section, and a sheath coupled between the distal section and the proximal section. The distal section includes an active area with a patterned, textured surface that is configured to apply radiofrequency (RF) energy, cryogenic cooling, or laser energy output to a portion of target tissue, such that the portion of target tissue is ablated. The patterned, textured surface of the active area is configured to maintain contact between the target tissue and the active area.

Abstract: A WCD system is configured to monitor various characteristics of the WCD system including about the patient. The information collected by the WCD is generally referred to as “patient information.” The WCD system is further configured to transmit certain of the patient information to different recipients based on predetermined profiles with which one or more of the recipients is associated. In various embodiments, different sets or subsets of the patient information may be sent to different recipients.

Abstract: The present disclosure relates to mapping catheters, and in particular to mapping catheters having thin film electrodes used in sensing electrical activity within a patient. Particularly, aspects of the present disclosure are directed to a medical device having a hollow core, a balloon disposed over at least a portion of the hollow core, and a flexible framework having one or more thin film elements formed on at least a portion of the balloon. The one or more thin film elements comprise a plurality of mapping electrodes.

Abstract: Described herein are methods for monitoring or modulating an immune system in a subject; treating, reducing or monitoring inflammation; monitoring blood pressure; treating hypertension; or administering or adjusting a therapy for inflammation or hypertension in a patient by electrically stimulating the splenic nerve or detecting splenic nerve activity using an implanted medical device. Also described herein are implantable medical devices for performing such methods. The implanted medical device includes an ultrasonic transducer configured to receive ultrasonic waves and convert energy from the ultrasonic waves into an electrical energy that powers the device, two or more electrodes in electrical communication with the ultrasonic transducer that are configured to electrically stimulate a splenic nerve or detect a splenic nerve activity, and optionally a splenic nerve attachment member.

Abstract: Embodiments of the present disclosure provide a method and apparatus for filtering and surgical procedures. An exemplary apparatus includes an evacuation tube having a filter, a long axis and a hollow conduit extending through the long axis, the hollow conduit fluidly connecting a tube inlet and a tube outlet, the filter located within the hollow conduit operable to remove particles from a flow passing through the hollow conduit from the tube inlet to the tube outlet.

Abstract: Variable amplitude signals for neurological therapy, and associated systems and methods are disclosed. A representative method includes activating automatic delivery of an electrical therapy signal to a patient's spinal cord region at a frequency in a frequency range between 1.5 kHz and 100 kHz, via at least one signal delivery contact carried by an implanted signal delivery device. The delivery can include repeatedly and automatically delivering the electrical therapy signal at each of multiple therapy signal amplitudes to the at least one signal delivery contact, without the therapy signal generating paresthesia in the patient. The foregoing process can be used as a screening tool to screen responders from non-responders in the context of a non-paresthesia-generating therapy, and/or can be used during long-term treatment, for example, for chronic pain.

Abstract: A mask instrument includes a flexible mask and a controller. The flexible mask includes a first flexible layer, a second flexible layer, a plurality of functional layers located between the first flexible layer and the second flexible layer, and a plurality of electrodes electrically connected with the plurality of functional layers. The flexible mask is electrically coupled with the controller via the plurality of electrodes. The second flexible layer comprises at least one hole at a position corresponding to the plurality functional layers, and at least one portion of the plurality of functional layer is exposed out of the second flexible layer from the at least one hole. A method for using the mask instrument is further provided.

Abstract: Featured are intravaginal devices and methods of using the devices to observe the state of an individual's pelvic floor muscles in order to diagnose, treat, or prevent pelvic floor disorders (e.g., pelvic organ prolapse and incontinence) and their accompanying symptoms and methods of using the devices to treat or prevent vaginal disorders (e.g., skin laxity) in a subject using an energy transmitter (e.g., a radiofrequency transmitter).