Abstract: A device for shaping and cutting a bone graft comprises a main body extending along a longitudinal axis from a lower end to an upper end and having inside it a housing for the insertion of the bone graft to be shaped, an upper opening located at the upper end for the insertion of the bone graft into the housing, a lower support designed to support the bone graft, and an upper surface defining a cutting plane placed at the upper end and containing said upper opening, wherein the cutting plane is inclined with respect to the longitudinal axis by an angle ranging between 90° and 30°, preferably between 90° and 60°.

Abstract: Unicompartmental tibial components are described herein. A first unicompartmental component (10) comprises a plate (12) having a bearing surface (18) and an opposing surface (22) that is configured to be secured to a proximal end of a patient's tibia, wherein the plate further comprises an anterior end (24), an outer side (25), a posterior end (26) and an inner side (27), wherein a mediolateral width W of the plate is defined between the outer and inner sides, and a longitudinal anteroposterior axis (28) extends between the anterior and posterior ends approximately one third of the width of the plate (i.e. ? W) from the lateral side, and defines a longitudinal axis length L of the plate. A first elongate peg (14) protrudes from the opposing surface in the anterior portion, the first elongate peg defining a first peg axis (32). A second elongate peg (16) protrudes from the opposing surface in the anterior portion, the second elongate peg defining a second peg axis (34).

Abstract: In one embodiment of the present disclosure, an implant system for securing tissue to bone, including a first fixation member releasably engaged to a first inserter, the first fixation member having a throughbore adapted to accept a filament therethrough and a cannulation extending from a proximal end of the first fixation member to a distal end of the first fixation member, the first inserter positioned through the cannulation and having a distal tip extending distally beyond the distal end of the first fixation member, and a second fixation member releasably engaged to a second inserter different from the first inserter, the second fixation member having a size capable of being positioned within the bonehole.

Abstract: An implantable prosthetic valve can include a radially expandable and collapsible annular frame comprising an inflow end and an outflow end and a plurality of struts forming a plurality of cells, where each of the plurality of cells defines an opening in the frame. A leaflet structure can be positioned within the frame and secured thereto. A plurality of sealing members can be secured to the plurality of struts of the frame, where each sealing member of the plurality of sealing members includes two opposite sides that are not secured to the frame to allow blood to flow through each sealing member along a path formed between the frame and the sealing members.

Abstract: A medical device for treating a heart valve insufficiency, with an endoprosthesis which can be introduced into a patient's body and expanded to secure a heart valve prosthesis in the patient's aorta. In an embodiment, the endoprosthesis has a plurality of positioning arches configured to be positioned with respect to a patient's aorta and a plurality of retaining arches to support a heart valve prosthesis. The endoprosthesis includes a first collapsed mode during the process of introducing it into the patient's body and a second expanded mode when it is implanted.

Abstract: A split type precisely-anchorable transcatheter valve-in-ring system comprises a split transcatheter valve-in-ring anchoring stent (10) and a transcatheter artificial biological valve-in-ring (20), wherein the shape and structure of the transcatheter valve-in-ring anchoring stent (10) are matched with the real structure of the annuloplasty ring and supravalvular and infravalvular tissues after three-dimensional reconstruction based on imaging data of a patient who have undergone valve failure after implantation of a annuloplasty ring (30), the transcatheter valve-in-ring anchoring stent (10) is firstly delivered to the patient's failed annuloplasty ring for release, deformation and alignment with the supravalvular and infravalvular tissues of the failed annuloplasty ring; the transcatheter artificial biological valve-in-ring (20) is delivered to the transcatheter valve-in-ring anchoring stent (10) for release, the stent of the transcatheter artificial biological valve-in-ring (20) deforms and expands to the f

Abstract: A cement restrictor inserter instrument (130) comprises an inserter (131) having a handle (132) at a proximal end, a cement restrictor attachment formation (137) at a distal end for releasably attaching a cement restrictor (150), a shaft (136) extending from the proximal end to the distal end and a stop (138) on the shaft and between the proximal end and the distal end; and a body (140) having a shape corresponding to the shape of an orthopaedic prosthetic implant, a spacer (142), a visible depth guide feature (190) and a releasable attachment mechanism by which the body is releasably attachable to the shaft, and wherein the spacer is configured to position the visible depth guide feature at a fixed position relative to the inserter when the spacer abuts the stop corresponding to a target cement restrictor position when the visible depth guide feature is aligned with a feature of a bone of a patient in which the cement restrictor is to be inserted.

Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein. A dual-wireform support frame including an upper and a lower wireform permits expansion of the valve by one or two valve sizes, for example, with a 2-mm gap between each valve size. The lower wireform has a relatively shallow undulation so that it may stretch apart by a small amount and then prevent further expansion of the valve.

Abstract: A reverse shoulder system can include, for example, a glenoid baseplate comprising a longitudinal axis, the glenoid baseplate further including a stem and a central channel within a sidewall of the stem. The stem can include a longitudinal axis. The longitudinal axis of the glenoid baseplate can be angled with respect to the longitudinal axis of the stem, wherein the longitudinal axis of the glenoid baseplate is not perpendicular with respect to the longitudinal axis of the stem. Other components including a glenosphere, tools, and methods of use are also disclosed.

Abstract: The present invention relates to a deformable body formed of at least 20% by volume of a polymer material in which individual polymer backbones have a plurality of functional groups capable of cross-linking to form a cross-link; said polymer material provided in a first less-cross-linked configuration; wherein said polymer material, upon application of a suitable stimuli, said stimuli causes cross-linking of said functional groups to form cross-linking between said polymer backbones such that said polymer material is in a second more-crosslinked configuration.

Abstract: A method for producing a composite demineralized bone matrix composition using a one-step process is described. The composite demineralized bone matrix composition is produced from the biologically-derived bone. In addition, the composite demineralized bone matrix composition contains bone minerals according to the original composition proportion in the bone and may provide a bone mineral content condition that is closest to that in an environment in which in vivo bone formation occurs. In addition, the composition contains a bone morphogenetic protein (BMP-2), and thus enables a stable and excellent bone formation effect to be derived.

Abstract: A collapsible and expandable prosthetic atrioventricular valve may include an outer stent, an inner stent, and a plurality of prosthetic leaflets mounted within the inner stent. The outer stent may have an atrial disc, a ventricular disc, and a plurality of posts coupling the atrial disc to the ventricular disc. A plurality of connectors may extend between the inner stent and the outer stent to couple the inner stent to the outer stent. The outer stent may be devoid of metal in a space circumferentially extending between adjacent ones of the plurality of posts. The space may extending approximately one half, approximately one third, or approximately one fourth of a circumference of the outer stent.

Abstract: This disclosure relates to systems, devices, and processes for performing a reverse shoulder arthroplasty using one or more patient-specific shoulder implants and can include a baseplate implant and a humeral stem implant, both of which can be designed and 3D-printed. In various embodiments, the baseplate includes a fixation member (e.g., a post) and a taper. In at least one embodiment, the fixation member and the taper can each be at any location and protrude from the baseplate at any angle. In at least one embodiment, the system includes a patient-specific pin guide and trial, which have features corresponding to those of the baseplate.

Abstract: Implantable devices including conduits that have markings along the length of the conduit are described herein.

Abstract: The acute and chronic devices and methods described herein include a body lumen fluid flow modulator including an upstream flow accelerator and a downstream flow decelerator. The fluid flow modulator preferably includes one or more openings that define a gap/entrainment region that provides a pathway through which additional fluid from a branch lumen(s) is entrained into the fluid stream flowing from the upstream flow accelerator to the downstream flow decelerator. Delivery devices including a sheath and inner assembly also are provided for delivering the flow modulator to the body lumen. The delivery device may maintain the flow modulator in its collapsed, delivery state upon retraction of the sheath for ease of readjustment within the body lumen prior to full deployment of the flow modulator within the body lumen.

Abstract: A transcatheter valve prosthesis including a tubular stent includes an interior skirt or skirt portion is coupled to and covers an inner circumferential surface of the stent, and an exterior skirt or skirt portion is coupled to and covers an outer circumferential surface of the stent. A prosthetic valve component is disposed within and secured to the interior skirt or skirt portion. The interior and exterior skirts or skirt portions may overlap to form a double layer of skirt material on the stent, or may be portions of a skirt that do not overlap such that only a single layer of skirt material covers the stent. When the stent is in at least the compressed configuration, at least one endmost crown may be positioned radially inwards with respect to the remaining endmost crowns formed at the inflow end of the stent in order to accommodate the exterior skirt.

Abstract: A prosthetic heart valve includes a radially collapsible and expandable stent, a cuff and leaflets sutured thereto. The heart valve extends axially between an inflow end and an outflow end and the stent includes a layout of struts and nodes having a hybrid combination of vertical struts and oblique struts in the form of diamond-shaped and half diamond-shaped cells. The layout of the structure is configured to preserve a low cell density of material used in the stent to reduce the stent profile while in a collapsed state and to improve the deployment accuracy of the stent into the native valve annulus.

Abstract: A prosthetic heart valve includes a collapsible and expandable annular frame. The frame includes a plurality of rows of hexagonal cells. Each of the hexagonal cells is defined by six struts, including: two opposing side struts extending parallel to each other, a first pair of angled struts extending from respective first ends of the side struts and converging to intersect with each other, and a second pair of angled struts extending from respective second ends of the side struts and converging to intersect with each other. The prosthetic heart valve can also include a valvular structure with a plurality of leaflets. The prosthetic heart valve can further include a sealing member.

Abstract: A system and method of remote guidance and alignment for endovascular fenestration of a vascular prothesis placed intraluminally that includes a flexible magnetic guide sheath having a magnetic distal end. An implantable magnetic stent for intraluminal placement in proximal end of a target artery providing magnetic guidance outside the endovascular aortic stent graft prothesis for accurate aperture formation in the vascular prothesis for subsequent placement of covered branch stents thereto.

Abstract: This disclosure relates to orthopaedic implant systems and methods for restoring functionality to a bone and/or joint. The implant systems disclosed herein may include a taper connection between components. A hydraulic actuation device may be utilized to separate the components at the taper connection. A method of disassembling orthopaedic components is also disclosed.