Abstract: Implantable devices for spinal cord and peripheral nerve injury are described. The implants include a three-dimensional printed structure having stem cells disposed therein. Also disclosed are methods of treating neuronal injuries with the disclosed implants.

Abstract: A stemless prosthetic shoulder joint may include a prosthetic humeral head and a stemless base. The stemless base may include a collar and an anchor extending from the collar intended to anchor the base into the proximal humerus. The base may include a proximal collar having a proximal surface and a bone-engaging surface opposite the proximal surface. The collar may have a superior portion and an inferior portion, the superior portion defining an arc shape and the inferior portion defining a substantially triangular shape.

Abstract: A reverse shoulder system can include, for example, a glenoid baseplate comprising a longitudinal axis, the glenoid baseplate further including a stem and a central channel within a sidewall of the stem. The stem can include a longitudinal axis. The longitudinal axis of the glenoid baseplate can be angled with respect to the longitudinal axis of the stem, wherein the longitudinal axis of the glenoid baseplate is not perpendicular with respect to the longitudinal axis of the stem. Other components including a glenosphere, tools, and methods of use are also disclosed.

Abstract: A bioabsorable stent is disclosed. The stent is made of a polymer and/or non-polymer material and has an elongated body having a proximate end, a distal end, and at least one open channel formed on the exterior surface of the elongated body to provide fluid communication between the proximal end and the distal end. Also disclosed is a bioabsorable stent having an elongated center rod having a proximate end and a distal end and a plurality of leaflets extending outward from the center rod and forming channels between two neighboring leaflets to provide fluid communication between the proximal end and the distal end.

Abstract: A low profile balloon expandable artificial prosthetic heart valve, particularly aortic, for transcatheter implantation comprises a valve frame of cylindrical structure. The cuff made of the polymer material is inseparably integrated with the frame so that the valve frame in the supporting section is embedded or sewn into and covered from the internal side and from the outside with the cuff material, which folded into the interior section of the frame and in the frame valve section is formed into valve leaflets in bicuspid or tricuspid configuration and in the said section it is attached to the frame and to the frame posts, and the cuff material excess is led into the longitudinal openings in the posts.

Abstract: A tibial spacer paddle comprises a spacer block comprising opposing bearing surfaces, an alignment slot extending into the spacer block; and a handle extending from the spacer block. The spacer block can include feet for passively engaging the femur or pegs for actively engaging a femoral component so that the spacer block is linked to the femur while the tibia rotates. A tibial spacer system comprises a provisional component having an alignment tab extending from a body and an alignment indicator located on the body, a femoral component and a pin extending from the femoral component. The pin can engage the alignment tab so that the provisional component is linked to the femur while the tibia rotates. In addition to or alternatively to the alignment tab and pin, the provisional component can include a tibial plate that can be rotationally connected to the provisional component.

Abstract: A modular reverse shoulder prosthesis, comprising: a stem (110) comprising a tapered body (111) and a first annular housing (112); a tray (120) comprising a dome element (121) for insertion into the first annular housing (112), and further comprising a second annular housing (122); a liner (130) comprising an engaging element (131) for at least partial insertion into the dome element (121), and further comprising a joint concave element (132) configured for coupling with the second annular housing (122). The second annular housing (122) of the tray (120) comprises a raised edge (123) configured to support the joint concave element (132) and which defines an overall outline having a different development in height at least in diametrically opposite portions (123a; 123b) of the tray (120).

Abstract: A surgical implant with recesses adapted to capture fixation medium that extravasates during implantation. The implant includes an elongated stem having a distal tip configured for insertion into an implant receiving area of a patient. A collar having recesses for capturing extravasating fixation medium is attached on the stem. The collar can be fixed to the stem by a separable collar-engagement feature or the collar can be fixed to the stem via structures on the stem.

Abstract: Disclosed herein is an implant. The implant can include a body and a plurality of fixation members. The body can define an articular surface and a bone engaging surface opposite the articular surface. The bone engaging surface can define a groove that separates a first section of the bone engaging surface from a second section of the bone engaging surface. The plurality of fixation members can extend from the bone engaging surface.

Abstract: A tandem modular endograft includes a main elongate tubular graft body having at least one circumferential inflatable channel disposed towards a proximal portion of the graft body wall and a plurality of circumferential inflatable channels disposed towards a distal portion of the graft body wall. A proximal expansion anchor is disposed at or secured to a proximal neck portion of the graft body wall. First and second elongate tubular stent-graft extensions may be percutaneously disposed into a distal end of the tubular graft body. In combination, proximal portions of the first and second stent-graft extensions are conformable to a shape of the open lumen of the main graft body.

Abstract: A humeral implant system, for example, includes an implant and a cutting guide system. The implant is a spherical wedge having an elongated curved upper surface having a first edge and a spaced apart second edge, a first surface having a curved upper edge joined to the first edge of the elongated curved upper surface, and a second surface having a curved upper edge joined to the second edge of the elongated curved upper surface. A lower edge of the first surface is joined to a lower edge of the second surface. The first surface and the second surface are disposed at an angle. The cutting system has a body having a first guide and a second guide for resecting a cutout in a humeral head, in which the cutout has a first surface and a second surface corresponding to the first surface and the second surface of the implant.

Abstract: A method of treating midface volume deficit in a person is provided. The method generally includes administering a dermal filler, such as a hyaluronic acid based dermal filler, in a sequence of injections that enhance effectiveness and/or duration of the filler. The method may include initially introducing a volume of the filler into at a zygomaticomalar region of the face prior to introducing one or more additional volumes of the filler into the anteromedial region and the submalar region, such that the duration of effectiveness of the treatment is improved, and less filler is required to achieve a desired correction.

Abstract: An implant includes a body including a substrate and a bone interfacing lattice disposed on the substrate. The bone interfacing lattice includes at least two layers of elongate curved structural members. In addition, the at least two layers of elongate curved structural members include a first layer adjacent the substrate and a second layer adjacent the first layer. Also, the first layer has a first deformability and the second layer has a second deformability, wherein the second deformability is greater than the first deformability. Further, one or more of the elongate curved structural members may have a spiraling geometry.

Abstract: An implantable vein frame is contemplated in which two ring members are rigidly joined in spaced axial alignment via one or more interconnecting members. One of the one or more interconnecting members defines a protruding region that acts upon the implant placed within the frame and/or the vein that the vein frame is placed within to define a sinus region. The implant is placed within and scaffolded by the vein frame, and the vein frame is subsequently inserted within a vein via a venotomy, or interposed between two vein segments via vein interposition graft. The vein frame acts to support the structural integrity of the implant, and to scaffold and anchor the implant in place with the vein.

Abstract: A contoured biological tissue for a bioprostheses, such as a cardiac/vascular patch or a bioprosthetic heart valve, and methods of contouring the tissue, are described. A predetermined pattern is provided on the tissue, comprising a plurality of ridges or depressions that are configured to facilitate cellular migration in a first direction and discourage cellular migration in a second direction. The biological tissue can be used in connection with a bioprosthetic heart valve comprising a biological tissue leaflet structure coupled to a supporting frame.

Abstract: Methods, systems and devices for pre-operatively planned shoulder surgery guides and implants. Pre-operative planning methods for designing glenoid implants and prostheses, particularly with patient-specific augmentation, based on considerations of multiple factors affecting the outcome of shoulder surgery. Methods of using surgery guides and implants, including adaptive glenoid implants, in patients undergoing shoulder surgery.

Abstract: Surgical constructs, assemblies, kits and methods of tissue fixation are disclosed. Glenoid augmentation is conducted with one or more soft tissue grafts placed on the anterior glenoid to fill a glenoid defect. Knotted or knotless suture anchors can deliver and fixate the soft tissue graft within the glenoid bone defect. Suture anchors can also secure the native ligament to the soft tissue graft and provide stability to the shoulder joint. Soft suture anchors can deliver and fixate a soft tissue graft within the bone defect. The native soft tissue can be repaired over top of the soft tissue graft into its anatomical position.

Abstract: A set of tools for installation of a stem implant into a bone comprises a stem-shaped priming tool (1) having a distal tip (32) and a plurality of cutting teeth (31) along a length thereof and a plurality of stem-shaped broaches (2, 3, 4, 5, 6) of different size. Each of the broaches have a distal tip (32) and a plurality of cutting teeth (31) along a length thereof. The priming tool (1) is shorter than, has more cutting teeth (31) per unit length, and has a sharper distal tip (32) than the smallest broach.

Abstract: A fitting ring can be provided that is attachable to an edge of a liner for an acetabular shell. The fitting ring can include an alignment portion shaped or configured to engage a lip portion of the acetabular shell as the liner is inserted into the acetabular shell to center the liner and correct any pivoting of the liner relative to the acetabular shell. A driving force can be applied to the liner to drive the liner into the acetabular shell while the fitting ring guides the liner as the liner is inserted into the acetabular shell. Driving the liner into the acetabular shell can also cause the fitting ring to disengage from the liner.

Abstract: Methods are described herein for delivering a replacement valve to a native valve location. In one method, ventricular anchors of the replacement valve are released and allowed to reverse orientation while positioned in the atrium of a human heart. After reversing orientation, the ventricular anchors extend in a generally proximal direction. The ventricular anchors can then be advanced through the annulus into the ventricle and then moved back toward the atrium to capture native valve leaflets between the main body and the ventricular anchors of the replacement valve. In one modification, the ventricular anchors are allowed to reverse orientation at a level adjacent the annulus. The implantation methods described herein are preferably performed via a transseptal delivery approach or a transapical delivery approach.