Abstract: Immunoassays are performed with two different ligands tagged with two different tagging constituents which are independent of each other and the two tagged ligands are immunologically bound together. The two different ligands may be detected independently through their independent tagging constituents for quality control, internal calibration (standardization), determination of viability and shelf life and the like.

Abstract: A novel glycopeptide is disclosed, which consists of a sugar moiety having a structural formula ##STR1## and a peptide moiety linking to the sugar moiety through N-glycoside bond. The glycopeptide is isolated from organs of normal animals, especially kidney, or urine from healthy human being, and has a biological activity of inducing lesions of kidney in animals. The lesions of kidney induced by an injection of the glycopeptide are very similar to spectrum of human glomerulonephritis. Accordingly, an experimental model for study on human glomerulonephritis is established.

Abstract: The present invention is a stabilized Romanowsky type stain solution. The stain solution which comprises azures, Methylene Blue and an eosin dye in methanol solution, is stabilized by the addition thereto of a stabilizing amount of a combination of dimethylamine hydrochloride and a second amine of the formula R.sub.2 NH.sub.2.sup.+ Cl.sup.- or R.sub.3 NH.sup.+ Cl.sup.- where R is ethyl, n-propyl or n-butyl.

Abstract: A diagnostic reagent for hepatitis A antibody is prepared by adhering hepatitis A antibody to a surface by non-specific adsorption followed by specific coupling of hepatitis A antigen to the antibody. This reagent is useful in an in vitro assay for hepatitis A antibody.

Abstract: Hybrid cell line for production of monoclonal antibody to an antigen found on all normal human helper T cells. The hybrid is formed by fusing splenocytes from immunized CAF.sub.1 mice with P3X63Ag8U1 myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.

Abstract: A reagent for the enumeration of oral gram-negative bacteria, such as Bacteriodes melaninogenicus, Capnocytophaga sp. and Eikenelia corrodens, by an indirect fluorescent antibody method is provided which utilizes an unlabelled antiserum to oral gram-negative bacteria and a fluorescent conjugated antibody obtained by immunizing an animal of a different species than the antiserum with .gamma.-globulin of an animal of the same species as the antiserum. A sample containing oral gram-negative bacteria to be enumerated is treated with the antiserum and the reaction product obtained is then treated with the fluorescent conjugated antibody to enumerate the bacteria in the sample by observing under a fluorescent microscope.

Abstract: The invention relates to a therapeutic mixture for treating bacterial and viral infections and exterminating parasites in human and animal host; comprises a therapeutically effective mixture consisting of cysteine sodium salt, and disodium sulfite, which in conjunction perform after injection a permanent reducing action liberating charged hydrogen, and charged aminothiopropionic acid radical, which are biologically active neutralizing and transforming bacteria and viruses, and kill the parasites.

Abstract: The invention relates to a therapeutic mixture for treating bacterial and viral infections and exterminating parasites in human and animal host; comprises a therapeutically effective mixture consisting of mercaptoacetic sodium salt, and disodium sulfite, which in conjunction perform after injection a permanent reducing action liberating charged hydrogen, and charged thioacetic radical, which are biologically active neutralizing and transforming bacteria and viruses, and kill parasites.

Abstract: The invention relates to a therapeutic mixture for treating bacterial and viral infections and exterminating parasites in human and animal host; comprises a therapeutically effective mixture consisting of mercaptolactic sodium salt, and dipotassium hydrosulfate, which in conjunction perform after injection a permanent reducing action liberating charged hydrogen, and charged thiolactic radical, which are biologically active neutralizing and transforming bacteria and viruses, and kill the parasites.

Abstract: A method for performing multiple, simultaneous in vitro diagnostic tests is provided. The method utilizes a solid phase device comprising a receptacle and an insert. The receptacle has one or more fixed components immobilized on its inner surface. The insert has one or more fixed components--different from those immobilized on the receptacle--immobilized on its surface which is in contact with a fluid sample when inserted therein. The test is performed by placing a fluid sample, having two or more mobile components reactive with the fixed components, into the receptacle and in contact with the insert for a period of time and measuring the changes which are a function of the concentration of the mobile components.

Abstract: New method for treating cardiac arrhythmia by administering cetiedil to a patient.

Abstract: A method of determining affective illness (i.e. mood disorders) involves serological testing. The serotonin uptake of the patient's blood platelets is determined and compared with a standard blood platelet serotonin uptake characteristic of a particular type of affective illness to determine the patient's type of affective illness. A method of treating a patient having a particular affective illness is provided which includes treating the patient with an effective amount of at least one drug which is effective in treating persons having the same blood platelet serotonin uptake as the patient.

Abstract: Novel hemostatic agent comprises equine arterial fibrillar collagen in a carrier. The agent is useful for the aggregation of platelets for clinical diagnostic tests and for the clotting of blood, such as for controlling bleeding in warm blooded species. The fibrillar collagen is obtained by extracting homogenized equine arterial tissue with aqueous solutions followed by extensive dialysis.

Abstract: An improved method of determining the nature of a substance by fluoroscence spectroscopy wherein a fluorescent marker is coupled to the molecules of the substance comprises the use of a marker having a longer period of fluorescence than those of possible sources of noise and by employing an exciting radiation pulse of short duration so that the fluorescence of the marker is detected after the objectionable sources of fluorescence have ceased; the marker including a fluorescent lanthanide chelate complex.

Abstract: A carcinostatic and immunostimulating agent containing a lysophospholipid and a phospholipid. Said carcinostatic and immunostimulating agent is useful for the treatment of cancerous diseases of the mammals including human being. This disclosure concerns such a carcinostatic and immunostimulating agent and a process for preparing the same as well as a method for treating the cancerous diseases by using said agent.

Abstract: A lectin is covalently bonded to an immunological conjugate such as an antibody-antigen or its equivalent. Then, the lectin-conjugate is isolated from the reaction product mixture by one of a number of alternative techniques involving one or more of the following types of reaction; (1) reversible reaction of the lectin with an insolubilized sugar to isolate lectin from the remainder of the mixture, (2) reaction of one immunological component (e.g., antibody) bonded to the lectin with an insolubilized corresponding component (e.g., antigen) to separate the antibody components from the remainder of the reaction mixture, and (3) filtration of the reaction components to separate on the basis of product molecular weight, size and/or shape of the components.

Abstract: A method of increasing the quantity of circulating high density lipoproteins and clearing cholesterol from certain tissues, comprising administering to a human an effective amount of a compound of the formula ##STR1## where X is H, OH, ##STR2## or NH.sub.2 ; R and R' identical or different are H, CH.sub.3 or C.sub.2 H.sub.5 ; m is zero or 1; and A is selected from the group comprising (CH.sub.3).sub.3 C--, Y--C.sub.6 H.sub.4 --, Y--C.sub.6 H.sub.4 --O--C(CH.sub.3).sub.2 --, Y--C.sub.6 H.sub.4 --C(CH.sub.3).sub.2 --, Y--C.sub.6 H.sub.4 --C(O)--C.sub.6 H.sub.4 --, Y--C.sub.6 H.sub.4 --(CH.sub.2).sub.n -- and Y--C.sub.6 H.sub.4 --O--(CH.sub.2).sub.n --, where n is an integer from 1 to 6 and Y is H, CH.sub.3, OCH.sub.3 or Cl.The present invention is a division of our copending application Ser. No. 114,423, filed Jan. 22, 1980, now U.S. Pat. No. 4,309,364.

Abstract: A bath additive or shower gel, comprising 20 to 70% by weight of a detergent blend (consisting of 10 to 90% by weight of an amine C.sub.8-18 fatty alcohol sulphate (optionally ethoxylated) and a metal or ammonium ethoxylated C.sub.8-18 fatty alcohol sulphate) and 20 to 60% by weight of a cosmetically acceptable oil, gives improved oil deposition.

Abstract: Pharmacologically acceptable chemotactic agents when applied to gingival crevices cause the migration of crevicular fluid containing crevicular leucocytes into the said gingival crevice.A quantitative correlation has been found between the amount of crevicular fluid migrating into the crevice and the crevicular fluid migrating into the crevice and the crevicular leucocytes contained therein after chemotactic challenge.It has further been shown that the amount of fluid and leucocytes migrating into said crevice gave a predictable relationship to the migratory activity of leucocytes obtained from the same subject when measured by conventional in vitro means.A rapid, convenient and simple method is thus provided for detecting certain diseases involving leucocyte migratory activity abnormalities for example diabetes mellitus and periodontosis.

Abstract: Hybrid cell line for production of monoclonal antibody to an antigen found on normal human monocytes and granulocytes. The hybrid is formed by fusing splenocytes from immunized BALB/cJ mice with P3X63Ag8U1 myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.