Abstract: A nasal spray containing an aqueous solution or a fluid with an anxiolytic or anticonvulsant substance, wherein the nasal spray is characterized in that with the nasal spray, two sprays with each an equivalent, defined volume of the aqueous solution or liquid of the active agent, can be intranasally administered to a patient. The nasal spray allows for an administration, independent of the spatial orientation of the nasal spray in any position of the patient (standing upright, sitting, lying or in any intermediate position). The nasal spray can be used directly without prior activation. It is apparent from the nasal spray whether a spray or even a second spray has been made with the nasal spray. A spray can be administered one-handed by the patient or a third person. The active agent is midazolam or a salt thereof.

Abstract: This disclosure relates to a nasal cannula without nostril prongs. The nasal cannula may be used together with an oxygen delivery system, such as a portable oxygen concentrator, or another type of breathing device such as a continuous positive airway pressure (CPAP) machine. In an example, a nasal cannula includes a tube configured to connect to an oxygen supply, and a fitting configured to connect to the tube. The fitting includes a single discharge port having a first section configured to be situated inferior to a first nostril of a user and a second section configured to be situated inferior to a second nostril of the user. Further, the fitting does not include nostril prongs. Because the fitting does not include nostril prongs, patient comfort is dramatically increased relative to prior designs.

Abstract: Disclosed are methods for measuring and controlling the gas temperature in medical procedures. In embodiments of the disclosed methods a gas is supplied to a patient using a gas supply device and a supply line. A heating system heats the gas using a heating wire prior to the gas being provided to the patient. A controller electrically controls the heating power of the heating wire based on an estimated value of a temperature at an exit of the heating system obtained from a mathematical estimation system, wherein a resistance of the heating wire is an input variable of the mathematical estimation system.

Abstract: Some embodiments provide for an inspiratory limb for a breathing circuit that includes a first segment that comprises a first heater wire circuit and a second segment that comprises a second heater wire circuit. The inspiratory limb can include an intermediate connector that includes a connection circuit that electrically couples the first heater wire circuit to the second heater wire circuit. The inspiratory limb can be configured to operate in two modes wherein, in a first mode, electrical power passes through the first electrical connection to provide power to the first heater wire circuit without providing power to the second heater wire circuit, and in a second mode, electrical power pass through the first electrical connection to provide power to both the first heater wire circuit and the second heater wire circuit.

Abstract: Provided is a system comprising an inhaler. The inhaler comprises a use determination system. The use determination system is configured to determine a parameter relating to airflow during a use of the inhaler by a subject. The use determination system also assigns a time to the use. The system also comprises a user interface, and a processing module. The processing module is configured to determine inhalation information from the parameter, and control the user interface to issue a notification that the inhalation information is available. The notification is issued at a notification time. The processing module is configured to implement a deliberate time delay such that the notification time is delayed relative to the time assigned to the use.

Abstract: A method for controlling a ventilator to provide variable volume (VV) with average volume assured pressure support (AVAPS), including: producing a VV target volume using a VV distribution function; producing a volume error Verror that is the difference between the VV target volume and a measured volume of the previous breath; scaling the volume error Verror; producing a VV target difference as the difference between VV target volume and the VV target volume of the previous breath; producing a modified volume error by adding the VV target difference to the scaled volume error Verror; producing a delta pressure support ?PS based upon the modified volume error and a dynamic compliance; and producing a current pressure support value based upon the delta pressure support ?PS and the pressure support value of the previous breath.

Abstract: An anesthetization gas mask for a small animal includes a first mask part providing an inlet for an anesthetization gas and a second mask part for transmitting the anesthetization gas. The first and the second mask part define an anesthetization volume for receiving an animal's mouth part. The second mask part transmitting the anesthetization gas is movably connected to the first mask part having the inlet for an anesthetization gas. The anesthetization gas mask is geometrically constructed such that a movement of the first mask part from a working position to a blocking position relative to the second mask part blocks the passage of anesthetization gas into the anesthetization volume. This anesthetization gas mask has a valve function integrated in the mask system itself, so that anesthesia gas is not spilled when not in use and with a fixed geometry so that the extraction is always present when handled.

Abstract: A patient interface comprises a support structure and a seal-forming structure. The support structure is arranged to support the sealing portion and is configured to connect to the frame. The sealing portion comprises textile and is attached to the support structure along an outer perimeter of the sealing portion such that in use the sealing portion may be in tension due to reactive stress of the support structure and/or a resilient stretch characteristic of the textile such that the sealing portion exerts a force against the patient's face.

Abstract: A humidifier heater base assembly has a heater plate with a thermally conductive portion and a perimeter portion around a perimeter of the heater plate. A resilient member has an inner part attached to the perimeter portion and an outer part adapted to provide a resilient perimeter flange around at least part and preferably the whole of the perimeter portion. The resilient member fixes the heater base to the humidifier by the resilient perimeter flange such that the heater plate and the inner part can move relative to the humidifier in a direction substantially transverse to the general plane of the heater plate. At least a portion of the resilient perimeter flange remains stationary relative to the humidifier.

Abstract: A patient interface pad with good comfort, configured to supply pressurized gas to an airway, includes a support section, an elastic section, and a comfort section. The support section and the elastic section together form a complete patient interface pad; the material of the comfort section includes foam, fabric, or a composite of both; the comfort section has different three-dimensional shapes and is connected to the patient interface pad to form the patient interface pad; the disclosure also discloses a manufacturing method for the patient interface pad with good comfort, as well as the connection method between the comfort section and the patient interface pad which is through an adhesive.

Abstract: A patient interface comprises a seal-forming structure including a textile membrane and a support structure to support the textile membrane. The seal-forming structure may have a varying construction in order to accommodate different regions and the varying contours of the patient's face to ensure a robust and comfortable seal. An air impermeable layer of the textile membrane may have a thickness that varies in different portions of the textile membrane and/or different regions of the cushion assembly. Further, the seal-forming structure may include an underlying cushion, and an arrangement of the textile membrane and the underlying cushion and/or the configuration of the underlying cushion may vary in different regions of the cushion assembly to optimize patient comfort and the effectiveness of the seal in different regions of the patient's face.

Abstract: A patient interface cushion and specifically a patient interface cushion with fabric, configured to supply pressurized breathing gas to the nasal and oral airways of a user. The patient interface cushion includes a rigid part, configured to support the elastic part, featuring a first opening and a second opening; The elastic part, configured to provide an attachment surface for the fabric part, featuring a third opening in communication with the second opening and a fourth opening allowing the user's nose and mouth to enter the internal cavity of the elastic part. The fabric part, configured to form a sealing area between the lower lip area and the nasal bridge area, featuring a first surface partially connected to the elastic part, a second surface sealing at least a portion of the user's face, and also having an inner edge and an outer edge.

Abstract: A patient interface assembly with optimized connection methods and improved air-tightness. The patient interface assembly forms a complete channel to deliver positive pressure air when connected with an air supply tube and a ventilator. The patient interface assembly includes a patient interface pad, a frame, an elbow assembly, and a quick-release connector. The patient interface pad is fixedly connected to one end of the elbow assembly. The frame is positioned between the elbow assembly and the patient interface pad. The other end of the elbow assembly is connected to the quick-release connector. By reducing the connection steps between parts, the air-tightness of the patient interface assembly is enhanced, and the patient interface assembly is adaptable to various types of frames.

Abstract: Positive airway pressure (“PAP”) systems and methods are provided which supply a patient with a range of pressures for treatment when the patient is determined to be asleep, and an awake pressure for use when the patient is determined to be awake, the awake pressure configured for the comfort of the patient. The awake pressure is configured to be lower than the lower bound of the pressure range and can be a therapeutic or sub-therapeutic pressure. The PAP systems and methods disclosed herein advantageously allow for the pressure range to be tailored for effective treatment of sleep disordered breathing while allowing the awake pressure to be set for the comfort of the patient. This can advantageously increase both the efficacy of the treatment of SDB and patient compliance with the treatment.

Abstract: The breathing assistance apparatus of the present invention includes a manifold that is provided with or retrofittable to gases supply and humidifying devices. The manifold allows gases from an oxygen concentrator to be combined with the flow through a gases supply and humidifying device, most usually air. The combined output of oxygen and other breathing gases (air) is then humidified. The breathing assistance apparatus and manifold of the present invention provides a safe method to add oxygen to the input air stream of a gases supply and humidifying device and reduces the amount of accumulation of oxygen within the gases supply device, reducing fire risk should sparking occur within the device.

Abstract: A ventilator system includes a ventilator and a host. The ventilator comprises a ventilation drive configured to drive ventilation gas from a gas source to a patient and a patient interface section configured to guide inspiratory gas along an inspiratory path from the ventilation drive to a patient connection, and guide expiratory gas along an expiratory path from the patient connection out of the ventilator. The patient interface section is configured to releasably connect to the ventilation drive. The ventilator is configured to removably connect to the host such that at least one of the inspiratory path and the expiratory path are diverted through the host when the ventilator is removably connected to the host.

Abstract: A respiratory treatment device includes a housing enclosing a chamber, a chamber inlet configured to receive a flow of air into the chamber, a first chamber outlet configured to permit the flow of air to exit the chamber, and a second chamber outlet configured to permit the flow of air to exit the chamber. A vane mounted within the chamber is configured to rotate between a first position where the flow of air is directed to exit the chamber through the first chamber outlet, and a second position where the flow of air is directed to exit the chamber through the second chamber outlet. A blocking member disposed on the vane is moveable relative to the chamber inlet between a closed position where the flow of air through the chamber inlet is restricted, and an open position where the flow of air through the chamber inlet is less restricted.

Abstract: An inhalation system including a fluid transfer member, a valve member, a cartridge assembly, and a mouthpiece, and a method of use thereof are provided. The valve member connects to an open end of the fluid transfer member. The cartridge assembly, positioned within the valve member, includes a substance holder and an absorbent member accommodated within a cartridge for containing and absorbing an inhaling substance. When the valve member connects to a vaporizer, the vaporizer heats the absorbent member to vaporize and release an inhaling fluid into the fluid transfer member. When the valve member connects to the mouthpiece, the valve member receives and transfers the inhaling fluid vapor from the fluid transfer member to a user's mouth via the mouthpiece. The locking mouthpiece assembly allows authentication of the user prior to releasing the inhaling fluid to the user's mouth.

Abstract: A clear, soft and malleable plastic constructed face mask is provided that has an elastic strap that is used to secure the mask onto a patient's face. The mask comprises of a malleable aluminium strip on the top for easy molding of the mask around the patient's nose; a front opening covered with a paper filter; and two side openings covered with a paper filter. The mask provides supplemental oxygen through connection to a Y-shaped respiratory/ventilator circuit or standard oxygen tubing. The mask also allows the patient to breathe comfortably without a supplemental oxygen source. It has ribbed tubing for gas sampling. The mask allows a health care employee to visualize breathing on the clear plastic material. The mask provides filtration of aerosolized contaminants.

Abstract: A nostril-shielding nasal mask includes a body including a top portion provided with an arcuate anterior section and arcuate posterior section engaged therewith, a hinge attached to the top portion, a bottom portion attached to the hinge and including a apertures aligned with the nostrils of the user, a scented and/or odor neutralizing air filter removably inserted into the bottom portion, and fasteners attached to the top portion and the bottom portion wherein the fasteners are configured to maintain the top portion and the bottom portion directly abutted against the nose bridge of the user and the nostrils of the user. The fasteners maintain the bottom portion at a first raised, non-operating position and a second lowered, operating position. The arcuate anterior section is engaged with the bottom portion when the bottom portion is disposed at the second lowered, operating position.