Patents Examined by Aradhana Sasan
  • Patent number: 10736866
    Abstract: Modified release formulations of gamma-hydroxybutyrate having improved dissolution and pharmacokinetic properties are provided, and therapeutic uses thereof.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: August 11, 2020
    Assignee: Flamel Ireland Limited
    Inventors: Claire Mégret, Hervé Guillard, Jean-François Dubuisson
  • Patent number: 10729673
    Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.
    Type: Grant
    Filed: January 30, 2020
    Date of Patent: August 4, 2020
    Assignee: Crititech, Inc.
    Inventors: Michael Baltezor, Joseph Farthing, Jake Sittenauer, Jahna Espinosa, Samuel Campbell, Matthew McClorey, Julia K. Fischer, Mark D. Williams, Gary E. Clapp
  • Patent number: 10729646
    Abstract: Described herein are methods for reducing the risks of exposure to air pollutants, comprising nasally administering to a subject in need thereof a composition that counteracts the effects of one or more air pollutants, wherein the composition is adapted for nasal administration. In some embodiments the composition comprises an agent that binds to one or more air pollutants, wherein the agent comprises one or both of nonporous silicon dioxide and porous silicon dioxide and/or the composition provides a physical barrier between one or more air pollutants and internal nasal surfaces. Also described are nasal compositions comprising an agent comprising one or both of nonporous silicon dioxide and porous silicon dioxide, a lipophilic or partly lipophilic vehicle, and a surfactant, wherein the composition is adapted for nasal administration. The compositions also may comprise other agents, such as an immunosuppressant. Also described are methods of making and using the compositions.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: August 4, 2020
    Assignee: M ET P PHARMA AG
    Inventor: Claudia Mattern
  • Patent number: 10729138
    Abstract: The present invention discloses a method for controlling surface-inhabiting pests in an aquatic system, in particular cyanobacteria and harmful algal blooms (HABs), comprising spreading on the surface of the aquatic system a buoyant composition comprising a water disinfectant, preferably an oxidizing compound, and a floating agent. The invention further relates to compositions and methods for their preparation and use.
    Type: Grant
    Filed: September 1, 2018
    Date of Patent: August 4, 2020
    Inventors: Sergei Braun, Moshe Harel
  • Patent number: 10722458
    Abstract: Chewable sustained release compositions and their methods of production are provided. The sustained release compositions contain amphipathic lipids and matrix-forming polymers, which are used to encapsulate various drugs and active ingredients. The chewable sustained release compositions can maintain their sustained release properties even after being fragmented into a plurality of pieces.
    Type: Grant
    Filed: May 31, 2013
    Date of Patent: July 28, 2020
    Assignee: Pegasus Laboratories, Inc.
    Inventors: Scott A. Howard, Troy Purvis
  • Patent number: 10722475
    Abstract: The invention relates to methods and materials for extending a circulating half-life of a protein. The method comprises conjugating a protein with a polymerizable acryloyl group and encapsulating the protein with a layer of poly(2-methacryloxyloxyethyl phosphorycholine) (pMPC). The layer of pMPC comprises a plurality of 2-methacryloxyloxyethyl phosphorycholine monomers (MPC) polymerized with a N,N?-methylenebisacrylamide (BIS) crosslinker.
    Type: Grant
    Filed: November 20, 2015
    Date of Patent: July 28, 2020
    Assignee: The Regents of the University of California
    Inventors: Yunfeng Lu, Yang Liu, Jing Wen, Gan Liu
  • Patent number: 10710791
    Abstract: The invention relates to a hair treatment process comprising the application to the hair of a composition comprising at least one fatty substance using an aerosol device comprising: —a container containing the composition and one or more propellants, it being possible for the propellant(s) to be present in the composition or, in the container, separate from the composition, —a means for dispensing said composition comprising: —a body (3) that is open at its two opposite axial ends, —an engaging part (10) that is open at its two opposite axial ends, at least partially defining a dispensing orifice (12).
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: July 14, 2020
    Assignee: L'OREAL
    Inventors: Nadia Smail, Lionel Aubert, Nicolas Albisetti
  • Patent number: 10704012
    Abstract: A method for formulating a cleaning composition contains the step of coating a granular absorbent material with a coating agent to produce a coated absorbent material and mixing the coated absorbent material with a sanitation agent, wherein the coated absorbent material absorbs the sanitation agent to form the cleaning composition. The resulting cleaning composition may be used for cleaning up pathogens or hazardous materials. The cleaning composition may also function as a liquefiable dry cleaning powder for public areas in response to bodily fluid incidents. A coating method of a non-toxic bio static film on a high surface area solid is disclosed.
    Type: Grant
    Filed: June 12, 2018
    Date of Patent: July 7, 2020
    Assignees: Morehouse School of Medicine, DevMar Products, LLC, Innovative Envirornmental Companies
    Inventors: Walter Hawkins, Sharon W. Reynolds, James W. Lillard, Jr.
  • Patent number: 10695285
    Abstract: The invention relates to an anti-pollution complex comprising an aqueous extract of Calendula, an oily extract of Calendula and an aqueous extract of Lilium candidum, to a cosmetic topical composition comprising such an anti-pollution complex and to a cosmetic process to protect the skin from the harmful effects of pollution, in particular from the harmful effects of exhaust gases and heavy metals.
    Type: Grant
    Filed: November 26, 2015
    Date of Patent: June 30, 2020
    Inventor: Jacques Leclere
  • Patent number: 10695291
    Abstract: Disclosed is an optimized pharmaceutical formulation for the treatment of inflammatory conditions of the esophagus. A pharmaceutical formulation in the form of an orodispersible effervescent tablet is stable, easy to produce, and can be used without dissolving same in a liquid. It is not necessary to drink anything with the tablet as this would reduce the time that the budesonide solution remains in the affected regions of the esophagus. The effervescent tablet of the invention surprisingly resulted in an unexpectedly high rate of histological remission in patients with active eosinophilic esophagitis.
    Type: Grant
    Filed: June 17, 2019
    Date of Patent: June 30, 2020
    Assignee: Dr. Falk Pharma GmbH
    Inventors: Roland Greinwald, Ralph Mueller, Markus Proels, Rudolf Wilhelm
  • Patent number: 10688041
    Abstract: Particles, compositions, and methods that aid particle transport in mucus are provided. The compositions and methods may include, in some embodiments, modifying the surface coatings of particles including pharmaceutical agents that have a low water/aqueous solubility. In some embodiments, a surface coating includes a synthetic polymer having pendant hydroxyl groups on the backbone of the polymer, such as poly(vinyl alcohol) (PVA). Such compositions and methods can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for administration routes involving the particles passing through a mucosal barrier.
    Type: Grant
    Filed: May 3, 2013
    Date of Patent: June 23, 2020
    Assignee: Kala Pharmaceuticals, Inc.
    Inventor: Alexey Popov
  • Patent number: 10688217
    Abstract: The present disclosure provides amine-modified polymer foams, which may be used for wound dressing materials. For example, the modified materials can include a covalently attached molecule comprising free amine groups. Such amine groups can be used, for instance, to conjugate biologically active polypeptides and/or linkers. Methods for using modified polymers are also provided.
    Type: Grant
    Filed: December 4, 2017
    Date of Patent: June 23, 2020
    Assignee: KCI Licensing, Inc.
    Inventors: Douglas Philip Hanson, James Courage
  • Patent number: 10682302
    Abstract: Disclosed are compositions and methods for their use that can be used individually or in combination. The compositions have the ability to treat a wide range of skin and skin conditions, and particularly men's skin.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: June 16, 2020
    Assignee: Mary Kay Inc.
    Inventors: Ricky Mendoza, Barbara Durkee, Greg Norman, Geetha Kalahasti
  • Patent number: 10682439
    Abstract: A three-dimensional porous polyurethane scaffold for repairing central nerve injuries and a preparation method are disclosed. The scaffold includes three-dimensional porous polyurethane, wherein the compression modulus of the three-dimensional porous polyurethane is 0.001-10.0 MPa and the pore diameter is 10-200 ?m. The three-dimensional porous polyurethane scaffold has an efficient central nerve repair function without additionally inoculating functional cells or factors and can partially restore the original nerve function of tested animals, the preparation method is simple and it has a great prospect of application.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: June 16, 2020
    Inventors: Hong Tan, Fang Fang, Jiehua Li, Yanchao Wang, Yingke Wu, Qiang Fu, Feng Luo
  • Patent number: 10675488
    Abstract: Disclosed are an acne removal composition, a skin care product and a preparation method thereof, wherein the acne removal composition is made from Garcinia mangostana L pericarp, thyme and Fructus aurantii.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: June 9, 2020
    Inventors: Wenjuan Deng, Guangrong Liu, Jian Tang
  • Patent number: 10675236
    Abstract: The present invention relates to a composition for cleansing and conditioning keratin fibres, in particular human keratin fibers such as the hair, comprising one or more anionic surfactants, one or more nonionic surfactants in a content of at least 3% by weight relative to the total weight of the composition, one or more amphoteric surfactants in a content of at least 3% by weight relative to the total weight of the composition, one or more particular cationic polymers and one or more amphoteric polymers. The invention also relates to a process for cleansing and conditioning keratin fibres and also to a use involving said composition.
    Type: Grant
    Filed: September 1, 2016
    Date of Patent: June 9, 2020
    Assignee: L'OREAL
    Inventors: Estelle Mathonneau, Marie-Florence D'Arras
  • Patent number: 10668106
    Abstract: The invention relates to an encapsulating chamber for secreting cells, comprising a closed shell made of a semi-permeable membrane, said membrane comprising at least one layer of porous biocompatible polymer, and one layer of non-woven biocompatible polymer.
    Type: Grant
    Filed: July 10, 2018
    Date of Patent: June 2, 2020
    Assignee: DEFYMED
    Inventors: Richard Bou Aoun, Severine Sigrist, Stefan Sproll
  • Patent number: 10660840
    Abstract: The present invention relates to a topical composition and more particularly a topical composition for antimicrobial benefit. According to the present invention there is provided a topical composition comprising Niacinamide and picolinamide wherein the molar ratio of Niacinamide to picolinamide is from 1:20 to 20:1.
    Type: Grant
    Filed: October 4, 2016
    Date of Patent: May 26, 2020
    Assignee: CONOPCO, INC.
    Inventors: Amitabha Majumdar, Mruthyunjaya Swamy Mathapathi
  • Patent number: 10653811
    Abstract: Articles are treated with a reduced amount of a halo active aromatic sulfanomide compound of Formula (I): wherein R1, R2, R3, R4, and R5 are independently selected from hydrogen, COOR?, CON(R?)2, alkoxy, CN, NO2, SO3R?, halogen, substituted or unsubstituted phenyl, sulfonamide, halosulfonamide, and substituted or unsubstituted C1-C12 alkyl; R? is hydrogen, an alkali metal, an alkaline earth metal, substituted C1-C12 alkyl, or unsubstituted C1-C12 alkyl; and R? is hydrogen or substituted or unsubstituted C1-C12 alkyl, where the two R? groups in CON(R?)2 may be independently selected; X is halogen; M is an alkali or alkaline earth metal; and n is the number of water molecules per molecule of the sulfonamide compound. The compound effectively suppresses odors pre-use, in use, and post-use for extended periods of time.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: May 19, 2020
    Assignee: Rem Brands, Inc.
    Inventors: David J. Schneider, Laura G. Kiely
  • Patent number: 10653597
    Abstract: The present invention relates to an antimicrobial composition and more particularly an antimicrobial composition for leave-on applications. The present invention discloses an antimicrobial composition comprising; a) 0.01 to 2% by weight of thymol; b) 0.01 to 2% by weight of terpineol; and c) 0.1 to 2% by weight of a cationic phospholipid complex.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: May 19, 2020
    Assignee: CONOPCO, INC.
    Inventors: Anindya Dasgupta, Qiong Gu, Kevin David Hermanson, Teanoosh Moaddel, Neha Salgaonkar, Bo Shen, Qiang Qiu