Abstract: An extracorporeal blood heating and cooling system that is connectable to an oxygenator of a cardiopulmonary bypass system, the heating and cooling system comprising: a heater-cooler unit; a coolant flow circuit that is configured to pass coolant through the heater-cooler unit and the oxygenator; and a cardioplegia coolant circuit that is configured to pass coolant through the heater-cooler unit and a cardioplegia heat exchanger; wherein when the heating and cooling system is in a purging mode, the coolant flow circuit and the cardioplegia coolant circuit contain temperature-controlled coolant having a trisodium phosphate concentration of about 1-35 millimole/liter; wherein when the heating and cooling system is in a coolant mode, the coolant flow circuit and the cardioplegia coolant circuit contain temperature-controlled coolant having a trisodium phosphate concentration of about 1-10 millimole/liter; and wherein when the heating and cooling system is in the coolant mode or the purging mode, a first and seco

Abstract: A combination hanger arm extension and pump cover device can be used with an instillation unit. The device includes a body portion that has a first end and a second end. A hook extends from the first end, and a tab extends from the body proximate the hook. A panel is disposed proximate the second end. A substantially rectangular sleeve extends at least partially through the body. The sleeve is disposed between the first and second end.

Abstract: A plasmapheresis bowl for the separation and collection of plasma includes a core and a feed tube that increase the bowl efficiency and reduce foaming within the plasma. The core may have a cylindrical body and a ledge located within the interior of the core. The ledge extends radially inward from the core and defines, at least partially, a collection chamber within the plasmapheresis bowl. The core also has ribs that extend above the top of core body and create flow paths that allow fluid to enter the interior of the cylindrical body and collection chamber. The feed tube has a flow path extending through it that fluidly connects an inlet port on the plasmapheresis centrifuge. A first skirt member on the feed tube has a smooth angled surface that helps to reduce foaming.

Abstract: Methods, devices, and systems for laser eye surgery generally make use of a console that interchangeably accepts multiple types of eye treatment cassettes. The cassettes enable one or both of displacement-based or vacuum-based aspiration. The console and the cassette may communicate to establish the functionality of the installed cassette by utilizing a component indigenous to the operation of the cassette. A dual-mode cassette may include a separable holding tank for enabling vacuum-based aspiration. A displacement-based pump may be provided to drain the holding tank while the vacuum system continues to aspirate fluids. A vacuum sensor for controlling the flow of aspirated fluids may have three ports for communicating with a handpiece, a displacement-based pump, a vacuum-based pump, or an irrigation source. The handpiece may be vented during vacuum-based aspiration by opening a vent valve interposed between the handpiece and the vacuum source.

Abstract: A monitoring device implements a monitoring method that comprises: activating a first monitoring technique that operates to detect the disruption and generate a corresponding alarm signal while a second monitoring technique is deactivated, obtaining at least one of a first count of false alarms generated by the primary monitoring technique and a second count of false alarms generated by the second monitoring technique if activated, and selectively, based on at least one of the first and second counts, activating the second monitoring technique to operate, instead of or jointly with the first monitoring technique, to detect the disruption and generate the corresponding alarm signal. The monitoring device may be connected to or part of an apparatus for blood treatment and operable to detect a disconnection of an extracorporeal blood circuit from a vascular system of a patient, e.g. a venous-side disconnection.

Abstract: A catheter pump assembly is provided that includes an elongate polymeric catheter body, a cannula, and a tubular interface. The elongate polymeric catheter body has a proximal end and a distal end. The cannula has an expandable portion disposed distally of the elongate polymeric catheter body. The cannula can also have another tubular portion that is proximal to the distal portion. The tubular interface has an outer surface configured to be joined to the tubular portion of the cannula and an inner surface. The inner surface is disposed over the distal end of the elongate polymeric catheter body. The tubular interface has a plurality of transverse channels extending outward from the inner surface of the tubular interface. An outer surface of the elongate polymeric catheter body projects into the transverse channels to mechanically integrate the elongate polymeric catheter body with the tubular interface.

Abstract: Connection pads for coupling fluid-instillation and negative pressure wound therapy (NPWT) apparatuses to wound dressing, and methods and wound dressings for breaching a drape after coupling a wound dressing to a fluid-instillation and/or NPWT apparatus.

Abstract: The present invention provides gastrointestinal devices for limiting transfer and contact of material across luminal walls along a segment of the gastrointestinal tract (e.g., at the duodenum and/or upper jejunum). Devices of the invention include a gastrointestinal sleeve, an anchor, and a flange for attachment to a luminal wall proximal to the pyloric orifice. The invention also provides methods of use associated with such gastrointestinal devices, including methods for delivery, removal, and treatment of metabolic disorders, such as type 2 diabetes, non-alcoholic steatohepatitis, non-alcoholic fatty liver disease, obesity, and related comorbidities thereof by implanting gastrointestinal devices.

Abstract: An object of the invention is to improve the diffusibility of body fluid such that the body fluid can be quickly absorbed. The sanitary napkin 1 represented by FIG. 3 includes an absorbing body 4 with a highly water-absorbent polymer 12 interposed between an upper layer sheet 10 disposed on the skin side and a lower layer sheet 11 disposed on the non-skin side. The upper layer sheet 10 has a plurality of first protrusions 14 forming first space parts 13 that are to be filled with the highly water-absorbent polymer and that expand to the skin side, and a plurality of second protrusions 16 forming second space parts 15, each of which having a smaller volume than each of the first space part 13, that are to be filled with the highly water-absorbent polymer and that expand to the skin side.

Abstract: A menstrual device includes a cup and an extractor. Within the cup is a hollow projection having a channel which communicates with a guide. A blunt tip of the extractor is guided by the guide and received in the hollow projection. The extractor further includes a helical section proximal to the blunt tip which is configured to securely engage the cup from within the hollow projection. A handle portion of the extractor facilitates advancement of the blunt tip and extraction of the extractor together with the cup, once the two are engaged with each other. In a specific embodiment, the guide has a free end with a larger opening than an opposite end which is adjacent the cup, to better guide the blunt tip into the hollow projection. The hollow projection can have a frictional surface or threading for the engagement to the helical portion of the extractor.

Abstract: Provided is a medication dispenser configured to discharge a liquid state medication stored therein by a pumping operation in a predetermined amount in a drop state and prevent a noise occurrence during medication discharge, and having a bacteria infiltration prevention function, wherein a flow path member and a second check valve are mounted in a liner, the second check valve is composed of a hemispherical cylinder mounted in an elevation space of the liner, having an open upper part, and of which a diameter decreases toward a lower end and includes a variable part in which the hemispherical cylinder is vertically variable and an opening and closing protrusion configured to perform supply and blocking of a flow path.

Abstract: The invention relates to an apparatus for carrying out an extracorporeal blood treatment in which a substitution fluid is administered to the patient, wherein the apparatus comprises an extracorporeal blood circuit and a substitution line opening into the extracorporeal blood circuit, wherein the substitution line has a pump for conveying substitution fluid into the extracorporeal circuit, wherein at least two, and preferably more than two, containers for the provision of a substitution fluid are connected separately and at the intake side of the pump to the substitution line, and wherein at least one pressure valve is arranged between the pump and at least one of the containers, said pressure valve allowing a flow of substitution fluid to the pump on an exceeding of an opening pressure.

Abstract: Drainage of body fluid from a first area of the body to a target area of the body can be accomplished by interconnecting an artificial non-blood fluid conduit with the venous and/or lymphatic system of the body. For example, an artificial non-blood fluid conduit can be inserted into the eye to fluidly interconnect the anterior chamber with a venous structure, such as an anterior ciliary vein, or lymphatic in a target location of the eye. The outflow end of the conduit can be positioned adjacent to and/or cannulated within the venous structure or lymphatic. Further, the conduit can optionally have an angiogenic material for stimulating growth of new blood vessels in the target location to fluidly interconnect the venous structure or lymphatic with the anterior chamber using the non-blood fluid conduit.

Abstract: The present invention regards an applicator device for the preparation and application of at least one medical substance, preferably a coloured liquid, comprising: a hollow chamber having a hosting end and an opposite distal end in communication with means for contact with the patient; a cartridge slidingly inserted into said hollow chamber, containing at least one first medical substance, and having a first end external to the hollow chamber, and a second end completely inserted into the hollow chamber; a breaking means positioned at the distal end, capable of establishing a fluid communication between the internal of the cartridge and the means for contact with the patient; said second end being sealed by a filled double layer closure system containing at least one second substance, preferably coloured, mixable and/or soluble with the first medical substance contained in the cartridge.

Abstract: A device and method for treating a wound of a patient with negative pressure is provided. The device comprises a pump chamber that has at least one moveable side of the chamber. The moveable side moves between an intake stroke and an exhaust stroke upon application of an electrical potential. Fluid is drawn into the pump chamber during the intake stroke and expelled from the pump chamber during the exhaust stroke. The pump system may have a magnetic or a piezoelectric element that drives the movement of the pump chamber side.

Abstract: Controllers for dry eye treatment apparatus and methods are described herein which generally comprise a patch or strip affixed to the skin of the upper and/or lower eyelids to deliver heat to the one or more meibomian glands contained within the underlying skin. The treatment strip or strips include one or more strips configured to adhere to an underlying region of skin in proximity to one or both eyes of a subject such that the one or more strips allow for the subject to blink naturally without restriction from the one or more patches. A controller is in communication with the one or more strips and is programmable to monitor a temperature of the one or more strips to provide a treatment therapy above a threshold temperature of, e.g., 39° C., and below a maximum temperature of, e.g., 48° C., over a treatment period of 12 minutes.

Abstract: Absorbent cores comprising a core wrap which comprises a liquid permeable substrate layer, the core containing from about 87% to about 100% of superabsorbent polymer and having a funnel-shaped swelling chamber. The area of the core is at least twice the area of the swelling chamber, and the core contains a water responsive immobilizing agent to immobilize the superabsorbent polymer prior to water insult. The funnel-shaped swelling chamber is a portion of the absorbent core containing superabsorbent polymer and delimited by continuous permanent seals. Two permanent continuous seals form first opposing funnel wall segments, wherein first opposing funnel wall segments collectively comprise a first chamber angle about 20° to about 120°, the first chamber angle being the sum of angles formed by each first opposing wall segment with respect to the longitudinal axis.

Abstract: A soft tip applicator attaches to a syringe for spreading expressed liquid from the syringe onto a surface, such as skin. A detachable hollow microneedle assembly supports transdermal injection of syringe contents.

Abstract: A canister for use in administering reduced pressure to a tissue site includes a center body, a first end cap, and a second end cap. The center body includes a first end, second end, and a number of fluidly separate body conduits. The first end cap is connected to the first end of the center body and includes a number of return conduits fluidly connecting one body conduit to another. The first end has a port for receiving a conduit in fluid communication with the tissue site. The second end cap is connected to the second end of the center body and includes a number of return conduits fluidly connecting one body conduit to another. The second end cap has a port for receiving a conduit in fluid communication with a reduced pressure source. The fluid connection between the body conduits and the return conduits creates a continuous, tortuous pathway.

Abstract: A plasmapheresis device includes a column or other flow mechanism in which plasma flows following separation of the plasma from cellular components like blood cells, platelets and the like. The column includes a moiety, such as an antibody, which selectively binds to galectin-3. By removing galectin-3 from the blood stream of a mammal by at least 10%, improvements in the treatment of inflammation, suppression of the formation of fibroses, and a variety of cancer treatments can be effected or improved. The device provides for multiple columns to remove a variety of elements but includes one which selectively removes galectin-3 from the blood flow. Other agents may be added to the plasma before recombination with the cellular components of the blood, and before returning the recombined flow to the patient.