Abstract: A waste management appliance includes a tubular body having a proximal end and a distal end, a cowl fastened to the tubular body at a first circumferential location in a vicinity of the proximal end, a balloon provided within the cowl, and an inflation lumen opening to an interior of the balloon and extending toward the distal end of the tubular body. The cowl extends outside of the tubular body to a second circumferential location spaced from the first circumferential location and is fastened to the tubular body at the second circumferential location. The balloon is inflatable to a desired extent within the cowl by injecting a predetermined amount of fluid into the balloon via the inflation lumen; the cowl restrains inflation of the balloon beyond the desired extent in the event of an injection of more than the predetermined amount of fluid into the balloon.

Abstract: The invention comprises an enema device configured for fluid delivery and evacuation management—which includes a retaining component for retaining a part of the enema device within the rectum, coupled with a collection component for collecting stool or liquid discharge received from the rectum. The device may additionally include a fluid delivery component to enable delivery of enema fluid to the colon, and/or a withdrawal component to support safe removal of the device from the patient.

Abstract: An apparatus for administering a drug onto an ocular surface of a subject, the apparatus including a probe holding means for holding a probe within the apparatus. The probe has a first part being made of a bio-compatible material, and a second part being made of a magnetic material, the first part having a proximal end connected to the second part and a distal end opposite to the proximal end, wherein the distal end of the first part is employed to carry the drug. The apparatus also has an induction coil and control circuit, wherein the control circuit controls the induction coil to produce a first magnetic force and a second magnetic force, in an alternating manner, to release the probe in a first direction and to retract the probe in a second direction, respectively, wherein, when released in the first direction, the probe administers the drug from the distal end of the first part upon touching the ocular surface of the subject.

Abstract: A packaged, sealed container system for stable storage of a formulation of an oxygen-sensitive pharmaceutical compound, the packaged, sealed container system comprising a primary container including therein a formulation of an oxygen-sensitive pharmaceutical compound, a secondary outer container comprising a first flexible sheet layer, an opposing second flexible sheet layer, and a seal disposed along a common peripheral edge of the first and second flexible sheet layers, such that the primary container is disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. An oxygen scavenger is also disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. The oxygen scavenger is in fluid communication with the contents of the primary container.

Abstract: Systems and methods are provided for a bodily fluid management system for pumping bodily fluid such as lymph. The bodily fluid management system may include an implantable pump with a rotor having a magnetic portion and inlet and outlet tubes that connect to a fluid chamber. The fluid chamber has a volume that can be selectively reduced or increased via the rotor. The rotor is designed to periodically open and close kinking valves at each of the inlet and outlet tube to permit bodily fluid to enter the fluid chamber during an intake cycle and exit the fluid chamber during a discharge cycle. The magnetic portion of the rotor may be caused to rotate by an external controller that is positioned outside of the body and adjacent to the pump. The external controller may have a magnet that magnetically interfaces with the rotor to cause the rotor to rotate.

Abstract: A liquid transfer device is provided for mixing a medicament additive contained within a vial with an infusion liquid contained within an infusion liquid container to form a medicated infusion liquid. The liquid transfer device includes a trifurcated connector body defining a barrel at a first end thereof, an IV spike at a second end thereof and a vial adapter lumen with a vial adapter secured thereto at a third end thereof. A plunger having an IV port is slidably engaged with the barrel to form a syringe integrated with the device. The syringe enables the device to flush out the flow path between the IV port and the IV spike connected to the medicated infusion liquid, and any residual unmixed medicament additive therein, after combining the medicament additive with the infusion liquid.

Abstract: The present disclosure provides methods and apparatus for administration of ophthalmic treatments into a patient's eye. Apparatus may include a wire form with a horizontal upper frame, temples that rest on or hook over the ears, nose pads, and semi-circular receivers to accept the tip of an eye drop-dispenser bottle. In some examples, distance sensing apparatus and signaling capabilities may be present to support the administration of ophthalmic treatments. In some examples, the apparatus may be enhanced for the purposes of aiding the application of eyedrops by a deep upper horizontal frame that rests on the forehead to prevent the apparatus, and thereby the eye dropper bottle, from approaching the eye too closely.

Abstract: Systems, methods, and apparatuses for irrigating a tissue site are described. The system can include a tissue interface and a sealing member configured to be placed over the tissue site to form a sealed space, and a negative-pressure source fluidly coupled to the sealed space. The system includes an irrigation valve having a housing, a piston disposed in the housing, a fluid inlet to fluidly couple a fluid inlet chamber to a fluid source, and a fluid outlet to fluidly couple a fluid outlet chamber to the sealed space. A piston passage extends through the piston and fluidly couples the fluid inlet chamber and the fluid outlet chamber, and a biasing member is coupled to the piston to bias the irrigation valve to a closed position. The negative-pressure source is configured to move the piston between the closed position and an open position to draw fluid to the sealed space.

Abstract: A device for collecting and processing bone fragments comprises a housing and a filter element disposed in the housing. The filter element at least partially defines a collection chamber for the collection of a composition comprising bone fragments. An inlet cap is releasably coupled to either the housing or to the filter element and configured to receive the composition. The inlet cap includes a body, an inlet port extending from the body and configured to be coupled to a surgical tool, and a spout extending from the body opposite the inlet port. The spout includes an injection port extending into the collection chamber of the filter element. A outlet cap is releasably coupled to the housing and is configured to be coupled to a vacuum source.

Abstract: In one aspect, a combinatorial drug delivery device is provided for delivering a predetermined selection of drug components. The device includes a plurality of modules, each including: a body having an interior volume; a spike plate movably disposed in the interior volume, the spike plate having a protruding cannula and first and second ports. The device also includes a base tray which includes: a framework defining a plurality of wells, each of the wells formed to insertingly receive one of the modules; for each of the wells, first and second inlet ports formed to interface with the first and second ports of the module being received in the respective well; passageways to connect certain wells with adjacent wells to permit fluid flow therebetween. For each of the wells, the spike plate of the respective module being maintained in a stationary position with the module being inserted into the well.

Abstract: A suction device is shown and described. The suction device includes a body, an input port configured to receive a flow of matter, a suction port, and a suction lumen that couples the suction port to the input port. In some embodiments the suction device is configured to couple with a surgical instrument for use in a surgical procedure.

Abstract: A barrier for use in negative pressure wound therapy can include a base layer and surface structures. The barrier can be used to reduce or prevent tissue ingrowth. A method of using a negative pressure wound therapy system can include positioning a perforated barrier in a wound. After positioning the perforated barrier in the wound, positioning a pad in the wound on top of the perforated barrier, positioning a seal on top of the wound to at least partially seal the perforated barrier and the foam in the wound, and applying negative pressure wound therapy to the wound.

Abstract: A device is disclosed that secures a capsule and accommodates puncturing of the capsule and extraction of a medication. The device includes a cavity that receives and secures the capsule. The device includes at least one opening that provides access to the cavity for extraction of the capsule contents.

Abstract: Systems and methods are provided for a bodily fluid management system for pumping bodily fluid such as lymph. The bodily fluid management system may include an implantable pump with a rotor having a magnetic portion and inlet and outlet tubes that connect to a fluid chamber. The fluid chamber has a volume that can be selectively reduced or increased via the rotor. The rotor is designed to periodically open and close kinking valves at each of the inlet and outlet tube to permit bodily fluid to enter the fluid chamber during an intake cycle and exit the fluid chamber during a discharge cycle. The magnetic portion of the rotor may be caused to rotate by an external controller that is positioned outside of the body and adjacent to the pump. The external controller may have a magnet that magnetically interfaces with the rotor to cause the rotor to rotate.

Abstract: An eye drop applicator includes an applicator body with a top cavity, a bottom cavity, and a dispensing channel connecting the bottom cavity with the top cavity such that a fluid can selectively flow through the dispensing channel to the top cavity. The top cavity includes an opening at a top end of the applicator body, and the bottom cavity includes a bottom opening at a bottom end of the applicator body. The bottom cavity may receive a portion of an applicator container within the bottom cavity to assemble the eye drop applicator with the applicator container containing the fluid to be dispensed.

Abstract: The present invention relates to transdermal therapeutic systems (TTS) for the transdermal administration of solifenacin.

Abstract: A packaged, sealed container system for stable storage of a formulation of an oxygen-sensitive pharmaceutical compound, the packaged, sealed container system comprising a primary container including therein a formulation of an oxygen-sensitive pharmaceutical compound, a secondary outer container comprising a first flexible sheet layer, an opposing second flexible sheet layer, and a seal disposed along a common peripheral edge of the first and second flexible sheet layers, such that the primary container is disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. An oxygen scavenger is also disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. The oxygen scavenger is in fluid communication with the contents of the primary container.

Abstract: The invention presents a universal eyedrop adapter designed for efficient and hygienic eye drop administration. The adapter features a one-way valve at the top to prevent backflow, a reduced internal lumen to minimize drop wastage, and a controlled flow design for precise dispensing. The base incorporates spiral grooves for a secure fit and to prevent outflow. Constructed with an antimicrobial material, the adapter is bug-resistant, ensuring a clean application process. The ergonomic design includes a bent angle and a rounded tip to mitigate the risk of eye injury. The administration process involves attaching the adapter to most eyedrop containers, cleaning it and the receiving periorbital region with a sterile wipe, squeezing to dispense a drop at the rounded tip, and then touching the lateral canthus. The user blinks to utilize surface tension and a lateral-to-medial movement, bringing the drop onto the ocular surface.

Abstract: Multi-dose preservative-free ocular fluid delivery devices are provided. The fluid delivery device includes a fluid dispensing system and a fluid package for storing a liquid therein and supplying said liquid to the dispensing system. The dispensing system comprises an elongated chamber which includes a check valve which defines a frontal closure to the chamber. The valve is normally closed and hermetically seals the chamber. The dispenser includes a vibration motor that induces oscillations to the chamber and to the fluid within. The oscillations of the chamber impart momentum to the fluid stored in the chamber which in turn imparts force that cyclically opens the valve to dispense streams or liquid droplets. Fluid is dispensed only when the motor oscillates while otherwise the valve is hermetically closed. The fluid package can be made collapsible to remove the need to vent it.

Abstract: A urine collection device includes a collection member extending from a proximal end to a distal end. The proximal end includes an opening that provides access to an internal cavity of the collection member. The internal cavity includes a first chamber in fluid communication with a second chamber. The urine collection device includes a spacer in the second chamber, a first attachment member extending from a bottom wall of the collection member at the proximal end, a second attachment member extending from a top wall of the collection member at the proximal end, and an outlet for egressing urine from the internal cavity of the collection member. The first attachment member defines an aperture. The collection member is suitable to (i) direct urine from the first chamber to the second chamber and (ii) direct the urine in the second chamber distally toward the outlet.