Abstract: In certain embodiments, the present invention provides methods of identifying and treating a transplant recipient patient having transplantation tolerance induced by apoptotic donor leukocytes infused under cover of transient immunotherapy.

Abstract: The invention is in the field of coagulation diagnostics and relates to a method for detecting lupus anticoagulant.

Abstract: A field effect transistor, FET, gas sensor device (100) arranged to sense gas, and a method of sensing gas by a FET gas sensor device, are provided. The FET gas sensor device comprises at least one gate (110a, 110b), a source (120), a drain (130), and a semiconductor channel (140). The semiconductor channel and the gate(s) form a FET channel-gate coupling (150) by which an applied gate potential is arranged to control a current flowing through the semiconductor channel. The FET gas sensor device further comprises space(s) (200) arranged between the gate(s) and the semiconductor channel and configured to receive gas, whereby received gas is arranged to influence electrical property(ies) of the FET channel-gate coupling, and wherein the FET gas sensor device is arranged to sense gas based on the influenced electrical property(ies) of the FET channel-gate coupling.

Abstract: A biological indicator includes: a BI housing; a germinant container inside the BI housing and housing a germinant composition; a germinant releaser configured to release the germinant composition from the germinant container; a germinant releaser support supporting the germinant releaser and configured to bring the germinant releaser into contact with the germinant container upon application of a force to the germinant releaser support or the germinant container; a first spore carrier inside the BI housing, the first spore carrier having a plurality of spores deposited at a first surface thereof; and an imaging window at a first surface of the BI housing. A BI reader is configured to detect and quantify the presence of live spores in the BI, and includes an excitation source, a camera for capturing images of the spores over time, and a processor for analyzing the images to determine the presence of live spores.

Abstract: Embodiments of the present disclosure include methods and systems for detecting the presence of endotoxins in filters. For example, embodiments of the present disclosure are directed to methods and systems for improving in-process controls by detecting undesirable quantities of endotoxins in filters containing naturally-sourced materials prior to using those filters in the production of formulated drug substances.

Abstract: Systems and methods for a treatment of chemical sensors placed in a wellbore. A method may comprise providing a chemical sensor disposed in a sensing chamber, wherein the chemical sensor is on an optical fiber installed in a wellbore; optically interrogating the chemical sensor with the optical fiber; and pumping a treatment fluid through a fluid supply line and into the sensing chamber.

Abstract: In the present invention, among blood metabolites, amino acids, organic compounds and oxylipins that were statistically significantly differentiated from the control group, were selected from type 2 diabetes patients. Specifically, asparagine, aspartic acid, glutamic acid, cysteine, lysine, citric acid, and uric acid, and 12-oxo ETE, 15-oxo ETE, 9-oxo ODE, and 20-carboxy leukotriene B4, which are oxylipins, were confirmed to have cutoff values of AUC>0.7. In addition, the blood metabolites showed a significant difference between a DME patient group and a non-DME patient group, and thus were confirmed to be usable for accurate diagnosis of DME.

Abstract: The embodiments disclose an apparatus for testing organic plant materials for microbial contamination including machine-readable QR code identifiers associated with multiple facility testing locations, samples from each location are treated with microorganism-specific growth stimulator solutions and incubated locally in a portable incubator to accelerate microbial growth, a plurality of sensors and a camera, wirelessly coupled to a remote server, capture environmental data and images of the incubated samples, an artificial intelligence (AI) engine on the server analyzes the images and sensor data, correlates them to respective QR code identifiers, and compares them against a pattern recognition database to identify microbial contaminants, a mobile application displays AI-generated contamination reports, remediation recommendations, and a facility heat map identifying locations of recurrent infestations, a machine learning system continuously updates remediation determinations based on sensor feedback, an AI-e

Abstract: The present invention discloses an automated sterility testing assembly that has a needle holder sized and configured to selectively retain a needle fluidly coupled to a sterility testing filter. The holder is configured to move the needle in a first direction to pierce selected containers disposed on a carrier and to move the needle in a second direction opposite the first direction to remove the needle from the selected containers. The assembly includes a brace that braces the fluid containers during their respective piercings by the needle. Accordingly, the brace prevents the needle from moving the fluid containers out of the carrier.

Abstract: The present disclosure discloses an in situ U—Pb dating method for calcite, including: cutting a calcite sample to prepare an epoxy resin sample target; placing the sample in a laser ablation sample chamber, and adjusting a position of the sample in an optical axis direction; conducting line scanning ablation on the sample target, and measuring ion signal intensity data of 43Ca, 88Sr, 139La, and 238U; conducting two-dimensional (2D) element imaging to obtain a 2D element content distribution map; according to the 2D element content distribution map, determining a high-U analysis target area, conducting point ablation on the high-U target area, and measuring ion signal intensity data of 206Pb, 207Pb, and 238U; and after the element signal data is obtained, calculating 207Pb/206Pb and 238U/206Pb fractionation coefficients, correcting ratios of an unknown sample, constructing a Tera-Wasserbug diagram, and calculating age data and an initial Pb isotope (207Pb/206Pb) composition of the calcite sample.

Abstract: The invention provides assays and methods for detecting and monitoring systemic inflammation. Particularly, the invention in embodiments thereof relates to the use of urinary biomarkers for non-invasive determination of the level of inflammation.

Abstract: A fluorescent dye, as well as a preparation method and uses thereof, wherein the fluorescent dye is sensitive and specific to viscosity and has low background fluorescence; it can also be used as a fluorescent activated and lighted probe used for fluorescent labeling, quantification or monitoring of protein, enzymes or nucleic acid.

Abstract: The present invention relates to a device and a method for the analytical and/or sensory determination of the release of an active substance or several active substances from a release system. In particular, the present invention relates to a device and a method for determining the release of an active substance or active substances, in particular of an odiferous substance or flavoring or an odiferous substance or flavoring mixture, from a capsule or a precursor. Furthermore, the present invention relates to a device and a method for determining the properties of a release system, in particular of a capsule or a precursor. Ultimately, the present invention relates to the use of the device and method according to the invention for the analytical and/or sensory determination of the release of one or more active substances from a release system.

Abstract: In a sulfur chemiluminescence detector (SCD) including a heating furnace 210 including a combustion tube 211 and a heating means 215 for heating the combustion tube 211, an inert-gas introduction tube 214 that has the front end inserted into an end portion on an inlet side of the combustion tube 211 and has the rear end into which an end portion on the outlet side of a column 140 of a gas chromatograph is inserted, and inert-gas supplying means 264, 221, and 251 for supplying inert gas into the inert-gas introduction tube 214 in a manner that the inert gas flows from the rear end to the front end are provided. The inert gas (for example, nitrogen) flowing through the inert-gas introduction tube 214 can prevent the end portion on the outlet side of the column 140 from being exposed to oxygen. In this manner, generation of column bleeding caused by a decomposition product of the liquid phase can be suppressed, so that a decrease in the sensitivity of the SCD can be suppressed.

Abstract: A solution is proposed for testing a luminescence imaging apparatus (105). A corresponding method (700) comprises acquiring (706) a photograph image and finding (708) a position of the testing device (110) in the photograph image. The 5method further comprises acquiring (706) a luminescence image and determining (734-736) a representation of sites of the testing device (110), each comprising at least one luminescence substance, in the luminescence image according to the position of the testing device (110) in the photograph image. The luminescence imaging apparatus (105) is then tested (754-772) according to the representation of the sites (330) in the 0luminescence image. A corresponding computer program (600) and a computer program product for implementing the method (700) are also proposed. Moreover, a testing device (110) for use in the method (700) is proposed.

Abstract: A point of use analyte detection and quantification system for chemical applications is provided. Related methods are also provided.

Abstract: A corrosion rate estimation device for estimating a corrosion rate of a metal disposed in a predetermined environment includes an input unit that inputs water component information including information such as water content (time), temperature, conductivity, soil type, and the like, a corrosion rate estimation model configured to receive the water component information related to a water component contained in the predetermined environment as an input, and estimate the corrosion rate of the metal disposed in the predetermined environment from the water component information, and an output unit that outputs the estimated corrosion rate of the metal to the outside. The corrosion rate estimation model is generated using, for example, a machine learning algorithm such as a random forest, a neural network, or RNN (LSTM).

Abstract: Provided is a method for analyzing the content of D-lactic repeating units (D content) in polylactic acid that has a feature that the D content in polylactic acid can be quickly and accurately analyzed by using NMR data of polylactic acid and hypothetical polylactic acid without special chemical treatment for polylactic acid.

Abstract: This invention provides, among other things, methods for determining the average number of first polymers covalently attached to protein-first polymer conjugates in a solution.

Abstract: Disclosure herein are methods for determining whether or not an immunoglobulin is present above the polyclonal background level in a biological sample, and methods for determining whether an immunoglobulin contains a kappa or lambda light chain. These methods are useful for screening biological samples for the presence or absence of monoclonal gammopathy, and for diagnosing and monitoring monoclonal gammopathy in a subject.