Patents Examined by Arlen Soderquist
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Patent number: 11662301Abstract: Disclosed are a mine dust real-time detection system based on double-photoacoustic spectrometry and a detection method. The mine dust real-time detection system based on double-photoacoustic spectrometry includes a first sampling unit, a first photoacoustic detection cavity, a second sampling unit, a second photoacoustic detection cavity, a signal unit and a processing unit; the first sampling unit is used for sampling in respective, the first photoacoustic detection cavity provides a photoacoustic effect field to substances sampled by the first sampling unit, the second sampling unit is used for sampling in respective, the second photoacoustic detection cavity provides the photoacoustic effect field to substances sampled by the second sampling unit, the signal unit is used for providing a laser signal, and the processing unit is used for collecting and processing a photoacoustic signal.Type: GrantFiled: November 10, 2022Date of Patent: May 30, 2023Assignee: Anhui University of Science and TechnologyInventors: Huawei Jin, Lei Fang, Haowei Wang
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Patent number: 11656235Abstract: The subject invention provides materials and methods for single-step detection of target molecules in a sample. The methods and assays of the subject invention employ a dye-displacement strategy, in which aptamers complexed with a cyanine dye for sensitive and rapid detection of targets of interest. In the presence of a target, aptamer-target binding liberates the non-covalently bound aptamer-binding dye, resulting in optical changes that can be observed spectrophotometrically or with the naked eye. The methods and assays of the subject invention enable the colorimetric detection of targets of interest regardless of their structure, sequence, target-binding affinity, and physicochemical properties of their targets.Type: GrantFiled: August 7, 2021Date of Patent: May 23, 2023Assignee: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEESInventors: Yi Xiao, Obtin Alkhamis, Haixiang Yu
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Patent number: 11639917Abstract: The present invention relates to a dianhydride analysis method, which can reliably analyze a dianhydride having high reactivity and low solubility. In addition, the present invention can analyze the structure of impurities by separating the impurities on the basis of having a similar retention time in HPLC analysis, and can analyze the purity of the dianhydride with or without chromophores.Type: GrantFiled: September 23, 2019Date of Patent: May 2, 2023Inventors: Joon Seok Lee, So Yeon Kim, Bumgyu Choi, Byoung Hyoun Kim
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Patent number: 11624725Abstract: In various embodiments of the present disclosure, a molecular electronics sensor array chip comprises: (a) an integrated circuit semiconductor chip; and (b) a plurality of molecular electronic sensor devices disposed thereon, each of said sensor devices comprising: (i) a pair of nanoscale source and drain electrodes separated by a nanogap; (ii) a gate electrode; and (iii) a bridge and/or probe molecule spanning the nanogap and connecting the source and drain electrodes, wherein the molecular electronic sensor devices are organized into an electronically addressable, controllable, and readable array of sensor pixels.Type: GrantFiled: January 27, 2017Date of Patent: April 11, 2023Assignee: Roswell Blotechnologies, Inc.Inventors: Barry L. Merriman, Paul W. Mola, Chulmin Choi
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Patent number: 11598761Abstract: The present invention relates to a device (1) for measuring the oxidation stability and/or the thermal stability of any type of fuel, including diesel fuel, by miniaturization of the test system by use of a microfluidic technique. The physical phenomena to which fuels are subjected are reproduced by the microchannels (12) of the microfluidic chip (7), which comprise a representation of at least one of the fuel injection and the fuel circulation for a drive system, an internal-combustion engine or an aircraft reactor for example.Type: GrantFiled: August 30, 2018Date of Patent: March 7, 2023Assignee: IFP ENERGIES NOUVELLESInventors: Maira Alves Fortunato, Laurie Starck, Aurelie Mouret, Christine Dalmazzone, Nicolas Pannacci
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Patent number: 11598707Abstract: A medical analyzer and coagulation profiler performs various interrogations on specimens. A motor with reduction gearing moves and a video camera observes the samples, the cartridges or parts thereof. Changes in images are compared and recorded with a central processor that controls a display. Power supply, temperature controller, motor and gearing are mounted in a box which attaches to a smartphone. The smartphone provides the video camera, illumination and central processor that control the movement, temperature and display. The device makes testing simpler for small hospitals, clinics, ambulances, remote locations and individuals and controls a number of parallel or serial devices operating simultaneously or sequentially. A cartridge insertion actuates a circular motion to generate a blood profile based on changes. Change is analyzed with a video camera and processor such as in a smartphone and is plotted to show an amplitude and time. A smartphone provides a specific movement pattern.Type: GrantFiled: August 10, 2020Date of Patent: March 7, 2023Assignee: iFirst Medical Technologies, Inc.Inventors: Luke B. Joseph, Thomas A. Hasling
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Patent number: 11592425Abstract: Provided is a field-flow-fractionation apparatus that is configured to supply a carrier fluid to a waste fluid chamber through a fluid supply flow path at a flow rate higher than a set flow rate of a flow rate adjusting part at a timing between an end of analysis of a sample and a start of analysis of a subsequent sample, thereby forming a flow of the carrier fluid from the waste fluid chamber to the separation channel. Accordingly, the sample adhering to a separation membrane is separated from the separation membrane and is discharged from the outlet port.Type: GrantFiled: January 30, 2020Date of Patent: February 28, 2023Assignee: Shimadzu CorporationInventors: Yukio Oikawa, Shigeyoshi Horiike
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Patent number: 11573164Abstract: A method for determining properties of different cation exchange sites in a rock core sample, at a preserved state of the rock core sample may include providing a rock core sample that includes a plurality of indigenous exchangeable cations adsorbed onto the cation exchange sites, a plurality of cation exchange sites occupied by a crude oil, and one or more fluids occupying pore spaces in the rock core sample; subjecting the rock core sample to a plurality of coreflooding steps, the plurality of coreflooding step displacing the plurality of indigenous exchangeable cations, the crude oil, and the one or more fluids in at least three separate coreflooding steps to render the rock core sample clean of native components; determining an amount of indigenous exchangeable cations adsorbed onto the cation exchange sites; subjecting the rock core sample clean of native components to a plurality of coreflooding steps to determine a total amount of exchangeable cations adsorbed onto the cation exchange sites when the roType: GrantFiled: April 27, 2020Date of Patent: February 7, 2023Assignee: SAUDI ARABIAN OIL COMPANYInventor: Quan Chen
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Patent number: 11559806Abstract: The present invention generally relates to the manipulation of species using acoustic waves such as surface acoustic waves. In some aspects, a channel such as a microfluidic channel may be provided having two or more outlets, and acoustic waves applied to species within the channel to determine which outlet the species is directed to. For instance, surface acoustic waves may be applied to a species such as a cell or a particle to deflect it from the channel into a groove or other portion that directs it to a different outlet. In some cases, surprisingly, this deflection of species may be in a different direction than the incident acoustic waves on the channel. Other embodiments of the present invention are generally directed to kits including such systems, techniques for producing such systems, or the like.Type: GrantFiled: August 25, 2016Date of Patent: January 24, 2023Assignee: President and Fellows of Harvard CollegeInventors: David A. Weitz, Warren Lloyd Ung, Thomas Franke
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Patent number: 11525779Abstract: An object is to measure absorbance of aqueous cosmetic materials that have not heretofore been studied for absorbance measurement, and particularly to form a uniform layer of thin film in order to ensure accurate measurement without causing these aqueous cosmetic materials, which are O/W emulsions, to undergo phase separation during measurement. As a means for achieving the foregoing, an absorbance measurement method is provided, wherein an absorbent aqueous composition is applied on the surface of a substrate, which surface has been plasma treated, arc-discharge treated, or corona-discharge treated, to achieve a contact angle with pure water of 0 to 70.0 degrees, and the applied absorbent aqueous composition is measured for absorbance.Type: GrantFiled: August 31, 2017Date of Patent: December 13, 2022Assignee: KEIO UNIVERSITYInventors: Kouichi Asakura, Akihiro Kuroda
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Patent number: 11493449Abstract: When an operation receiver receives an operation for starting automatic start-up processing, a display controller causes a display to display a first direction image indicating a working order of a plurality of objects to be controlled, sequentially changes a display mode of a status image corresponding to an object that has worked to a first mode, and changes a display state of each of a plurality of operation images to an operable first state or an inoperable second state. When the operation receiver receives an operation for starting automatic stop processing, the display controller causes the display to display a second direction image indicating a stopping order of the plurality of objects in a reversed manner of the first direction image, sequentially changes a display mode of a status image corresponding to an object that has stopped to a second mode.Type: GrantFiled: August 13, 2019Date of Patent: November 8, 2022Assignee: Shimadzu CorporationInventors: Takuya Isoi, Yasuhiro Kimoto
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Patent number: 11486830Abstract: The present invention provides a method for determining a sensitivity to ultraviolet light non-invasively and immediately. A method for determining a UV sensitivity is provided involving: a step of irradiating the skin of a test subject with ultraviolet light to determine the UV sensitivity using the amount of biophotons to be detected within a specific period after the irradiation, wherein 50% or more of the specific period overlaps a period from 1 to 3 minutes after the irradiation.Type: GrantFiled: December 28, 2018Date of Patent: November 1, 2022Assignee: KAO CORPORATIONInventors: Yu Gabe, Shinya Kasamatsu, Osamu Osanai, Katsuya Takeda, Yoko Nakajima
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Patent number: 11484614Abstract: Water-based formulations comprising an indicating composition dispersed in water are described. The water-based indicating compositions include an organic Bi(III) compound, a sulfur source, a carbonate salt, and strontium hydroxide. Formulations further including a resin and/or an acidic additive are also described.Type: GrantFiled: June 25, 2020Date of Patent: November 1, 2022Assignee: 3M Innovative Properties CompanyInventors: Wensheng Xia, Sarah J. Davis
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Patent number: 11480523Abstract: A testing device (10) for testing the level of a selected chemical in central heating system water in a central heating system circuit comprises: a sample chamber (14) for holding a sample of central heating system water to be tested, the sample chamber (14) being connectable (12) to the central heating system circuit to allow fluid to pass between the central heating system circuit and the sample chamber (14); means (16) for controlling filling of the sample chamber (14) with central heating system water from the central heating system circuit, and emptying of the sample chamber (14); at least one valve (18) for isolating the sample of central heating system water from the heating circuit during testing; and optical testing apparatus including a light source (20) and a detector (22), for measuring an optical property of the sample of central heating system water isolated within the sample chamber (14) and thereby making a determination as to whether or not the level of the selected chemical in the water is gType: GrantFiled: July 27, 2018Date of Patent: October 25, 2022Assignee: ADEY HOLDINGS (2008) LIMITEDInventors: Mukash Jassal, Simon Downie
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Method for identifying a biomarker indicative of a reduced drug response using a thermal shift assay
Patent number: 11480578Abstract: The present invention concerns a method for identifying and using a biomarker, or creating a proteome profile, indicative of a reduced response to a drug in a patient involving a thermal shift assay on a sample. The method comprises the steps of a) heating a sample from a patient b) separating soluble from insoluble protein, c) analysing either or both the soluble and insoluble protein fractions of step b) to determine the melting temperature.Type: GrantFiled: March 25, 2015Date of Patent: October 25, 2022Assignee: PELAGO BIOSCIENCE ABInventors: Daniel Martinez Molina, Par Nordlund -
Patent number: 11474040Abstract: A process of utilizing a water-sensitive fluorophore for moisture content evaluation in a hygroscopic polymer includes forming a blend that includes a hygroscopic polymer resin and a water-sensitive fluorophore. The process includes forming pellets having a particular geometry from the blend, determining fluorescence properties of at least one of the pellets, and determining moisture content of at least one of the pellets. The process also includes generating a calibration curve for the particular pellet geometry by correlating the fluorescence properties with the moisture content. The process further includes providing the calibration curve for non-destructive moisture content evaluation of a material derived from the pellets.Type: GrantFiled: April 18, 2019Date of Patent: October 18, 2022Assignee: International Business Machines CorporationInventors: Eric J. Campbell, Sarah K. Czaplewski-Campbell, Joseph Kuczynski, Timothy J. Tofil
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Patent number: 11474099Abstract: The invention relates to a novel method for diagnosing the sulfur nutrition state of a plant by measuring the content of certain mineral nutrients in the leaves.Type: GrantFiled: February 3, 2017Date of Patent: October 18, 2022Assignees: AGRO INNOVATION INTERNATIONAL, UNIVERSITE DE CAEN BASSE NORMANDIEInventors: Elise Sorin, Mustapha Arkoun, Florence Cruz, Jean-Claude Yvin, Anne Maillard, Sylvain Diquelou, Philippe Etienne, Alain Ourry
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Patent number: 11474088Abstract: The present invention relates to a method for determining the origin of glutamic acid in a sample and, in a broader sense, relates to a method for determining the origin of an amino acid. The present invention makes it possible to measure the stable isotope ratio, with a considerably higher accuracy than that of conventional methods, by measuring the ?13C of glutamic acid (amino acid) by elemental analysis-stable isotope ratio mass spectrometry (EA-IRMS) and measuring the ?15N by gas chromatography-stable isotope ratio mass spectrometry (GC-IRMS). In addition, the present invention makes it possible to determine the origin of glutamic acid (amino acid) by comparing the stable isotope ratio of the glutamic acid (amino acid) whose origin is unclear with the stable isotope ratio of glutamic acid (amino acid) whose origin is clear.Type: GrantFiled: January 31, 2018Date of Patent: October 18, 2022Assignee: NISSIN FOODS HOLDINGS CO., LTD.Inventors: Masaharu Tanaka, Yoichi Yatsukawa, Kazuhiro Kobayashi, Soichi Tanabe, Mitsuru Tanaka
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Patent number: 11474032Abstract: A scale composition determination device (10) determines that Fe2O3 has been generated in the outermost layer of a scale (SC) in the case where at least one of spectral emissivities at one wavelength and the other wavelength that are measured by radiometers for spectral emissivity measurement (21a, 21b) is not within a predetermined range including spectral emissivities of FeO at one wavelength and the other wavelength, and determines that Fe2O3 has not been generated in the outermost layer of the scale (SC) in the case where all of the spectral emissivities at one wavelength and the other wavelength that are measured by the radiometers for spectral emissivity measurement (21a, 21b) is within the predetermined range including the spectral emissivities of FeO at one wavelength and the other wavelength.Type: GrantFiled: April 25, 2018Date of Patent: October 18, 2022Assignee: NIPPON STEEL CORPORATIONInventors: Masato Sugiura, Hiroshi Tanei, Shuichi Yamazaki, Yasumitsu Kondo
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Patent number: 11454619Abstract: Systems for quantifying one or more target analyte concentrations in a process solution are provided and can be used, for example, in methods for quantifying a target analyte concentration. These systems and methods include continuous and batchwise automated titration methods that use titration chemistries to measure the target analyte concentration in the process solution using a multiwavelength detector. The methods provide for efficient and robust automated titration methods for a variety of target analytes and can include methods that analyze more than one analyte and that provide for a dynamic range for measurement of more than one target analyte concentration.Type: GrantFiled: April 9, 2019Date of Patent: September 27, 2022Assignee: Ecolab USA Inc.Inventors: Paul R. Kraus, John Wilhelm Bolduc, Robert J. Ryther