Abstract: A technology for efficiently discharging a bubble present in a fluid in a chamber is provided. There is provided a bubble discharging method carried out in a chamber including a microchip that includes at least one well or through hole to divide a space into a first space and a second space, the bubble discharging method including a pressurizing step of applying a positive pressure to a fluid in the chamber, and a valve opening/closing step of operating a valve for opening/closing a first flow path connected to the first space and/or a second flow path connected to the second space.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for processing recycled concrete aggregate (RCA).

Abstract: In one embodiment, a biological sample analyzer has a housing having at least one outer wall that defines a cavity therein, an air intake, and an air exhaust. A plenum is disposed within the cavity and has at least one plenum wall that defines an air duct therein. A receptacle, which can support a consumable holder containing a biological sample, is disposed within the internal cavity. At least a portion of the receptacle is supported within the air duct such that an air gap is defined between the receptacle and the at least one plenum wall. A heater applies heat to the consumable holder so as to heat the consumable holder when the consumable holder is supported by the receptacle. A fan forces air along a path that extends from the air intake, through the air gap, and to the air exhaust so as to cool the heater.

Abstract: A method for identification of characteristic components in a Kai-Xin-San by thin-layer chromatography (TLC) is provided, belonging to the technical field of pharmaceutical raw material detection and traditional Chinese medicine quality control. The method only needs to prepare two test solutions to simultaneously identify six characteristic components in the Kai-Xin-San, namely ginsenoside Rb1, ginsenoside Re, tenuifolin, ?-asarone, dehydrotumulosic acid, and pachymic acid. An automatic TLC spotting instrument can ensure even sampling and flat chromatographic bands and the silica gel G thin-layer plates after spotting are placed in the steam of the optimized developing solvent to allow pre-saturation.

Abstract: Disclosed are a method for the quantitative determination of an analyte in a test item using a NMR spectrometer, wherein the deuterated solvent used to dissolve the analyte is used as the internal standard, and specific reference substances for use in the method according to the invention. Further described is a method for determining the degree of deuteration of a deuterated compound.

Abstract: An autosampler includes an imaging portion configured to move in a horizontal plane direction and a vertical direction while maintaining a positional relationship with a needle. The imaging portion is configured to image a tip of the needle and top surfaces of from a position obliquely above the tip of the needle so that the tip of the needle, a top surface of a vial directly below the tip of the needle, and a top surface of a nearby vial are within a visual field. A distance between the tip of the needle and a target position is measured utilizing a visual field image of the imaging portion, and the tip of the needle is made to reach a target position based on the measured distance.

Abstract: Methods are provided for detecting the amount of one or more HRT panel analytes (i.e., estrone (E1), estrone sulfate (E1s), 17?-estradiol (E2a), 17?-estradiol (E2b), estradiol sulfate (E2s), estriol (E3), equilin (EQ), 17?-dihydroequilin (EQa), 17?-dihydroequilin (EQb), Equilenin (EN), 17?-dihydroequilenin (ENa), 17?-dihydroequilenin (ENb), and ?8,9-dehydroestrone (dE1)) in a sample by mass spectrometry. The methods generally involve ionizing one or more HRT panel analytes in a sample and quantifying the generated ions to determine the amount of one or more HRT panel analytes in the sample. In methods where amounts of multiple HRT panel analytes are detected, the amounts of multiple analytes are detected in the same sample injection.

Abstract: The invention relates to the detection of methylmalonic acid (MMA). In a particular aspect, the invention relates to methods for detecting derivatized methylmalonic acid (MMA) by mass spectrometry.

Abstract: Devices and systems for droplet generation and methods for generating droplets are described. In an embodiment, the devices and systems include a capillary configured to eject a droplet, such as in response to a voltage applied to an end of the capillary. In an embodiment, the devices and systems include a moveable stage configured to carry a multi-well plate and move the stage relative to the capillary such that the ejected droplet is selectively received by a well of the multi-well plate carried by the moveable stage.

Abstract: This disclosure provides systems, apparatuses, and methods for liquid transfer and performing reactions. In one aspect, a system includes a liquid transfer device having a housing having a pipette tip and a plunger assembly; and a reaction chamber, wherein the housing of the liquid transfer device is configured to sealably engage with the reaction chamber. In another aspect, a liquid transfer device including a housing having a pipette tip; and a plunger assembly disposed within the housing and the pipette tip, wherein a portion of the plunger assembly is configured to engage a fluid reservoir such that the plunger assembly remains stationary relative to the fluid reservoir and the housing moves relative to the plunger assembly.

Abstract: Disclosed is a specimen measurement method for measuring platelet aggregation of a specimen, and the specimen measurement method includes: automatically preparing a diluted reagent solution that contains a platelet-aggregating reagent diluted with a diluent; preparing a measurement sample that contains a predetermined concentration of the platelet-aggregating reagent, from the diluted reagent solution and the specimen; and performing optical measurement of the measurement sample.

Abstract: An airborne silica detection system provides a chemiluminescence reaction for quantitative assessment of silica on an automated basis. A prefilter allows reaction to be sensitive to particle sizes relevant to chronic respiratory diseases.

Abstract: Methods for determining protein and/or peptide concentration or molecular parameter, such as the extinction coefficient, and uses thereof.

Abstract: The embodiments disclose a portable microbial test kit including a plurality of organic materials configured to be processed for preservation and prevention of mold, bacteria infestations, rot, and decay and reduce and prevent any degradation, a storage facility, a plurality of hardware, and a plurality of equipment configured for storage and monitoring of the plurality of organic materials, wherein the hardware and the equipment are configured to monitor the condition of the organic materials during storage, a plurality of components coupled to the hardware and the equipment configured to electronically monitor the condition of the organic materials during storage, at least one electronic device coupled to the plurality of hardware and the plurality of equipment configured to report electronically the condition of the organic materials to the facility and customer, and a system coupled to the at least one electronic device configured for customers to automatically reorder hardware and equipment.

Abstract: An automatic analyzer includes a flow cell detector, a nozzle that is connected to the flow cell detector by a flow path and aspirates or discharges liquid, a reservoir that is provided with a table and a table driving mechanism that rotates or moves the table up and down, and a cleaning tank that is disposed on the table. A position of the nozzle is fixed, and a cleaning water discharge port discharges cleaning water used for cleaning the nozzle at an angle ? with respect to a plane perpendicular to a central axis of the nozzle. An upper part of a side wall of the cleaning tank is continuous with an upper discharge unit at a side facing a discharge outlet provided in the reservoir and a spatula-shaped part projects outward of the cleaning tank at a side facing the upper discharge unit.

Abstract: In an embodiment, the claimed invention includes an oral-fluid collection and testing device that. is simple to operate. The device includes a body assembly and a cap assembly that are easy to handle by a user. A collection sponge projects from an end of the body assembly for absorbing the oral fluid of a donor, A cap assembly is easily aligned with the body assembly by way of visual alignment indicators on both the body and the cap. Once the cap is aligned with the body, a user simply pushes the cap onto the ‘body, which causes a first stage fluid, flow. More specifically, a buffer fluid is released from the cap and mixes with the oral fluid collected on the sponge—After waiting a short time* the cap is rotated, then pushed again, causing a second-stage fluid flow in which the sponge is compressed such that the buffer fluid/oral fluid exits the sponge and flows toward a. pair of test strips.

Abstract: A medical analyzer and coagulation profiler performs various interrogations on specimens. A motor with reduction gearing moves and a video camera observes the samples, the cartridges or parts thereof. Changes in images are compared and recorded with a central processor that controls a display. Power supply, temperature controller, motor and gearing are mounted in a box which attaches to a smartphone. The smartphone provides the video camera, illumination and central processor that control the movement, temperature and display. The device makes testing simpler for small hospitals, clinics, ambulances, remote locations and individuals and controls a number of parallel or serial devices operating simultaneously or sequentially. A cartridge insertion actuates a circular motion to generate a blood profile based on changes. Change is analyzed with a video camera and processor such as in a smartphone and is plotted to show an amplitude and time. A smartphone provides a specific movement pattern.

Abstract: A handheld medical analyzer works with different disposable application cartridges to perform a variety of interrogations on specimen samples. One application includes attaching a biological microelectromechanical systems (BioMEMS) cartridge that generates blood coagulation profiles indicative of particular forms of coagulation disorders. The device makes coagulopathy testing simpler for small hospitals, clinics, ambulances, remote locations and individuals and permits for a larger number of parallel or serial devices operating simultaneously. One insertion of a cartridge actuates an oscillating circular motion to generate a blood coagulation profile based on a change in rotational motion as blood coagulates in a sample. Change in rotational motion is analyzed through a video camera such as in a smartphone and is plotted to show an amplitude over time. Actuation of the BioMEMS can be achieved by magnetic actuation of a motor controlled by an iPhone or a smart phone to provide a specific rotational pattern.

Abstract: Provided is a method for separating and detecting various hemoglobins including abnormal hemoglobins and thalassemia markers. A method for analyzing hemoglobins, comprising separating hemoglobins in a sample by cation exchange chromatography, wherein an eluent having a pH of 8.1 or more and an osmotic pressure of 40 mOsm/kg or less is used for separation of the hemoglobins.

Abstract: A composition includes a functionalized fluorescent dye. The functionalized fluorescent dye includes an isothiocyanate-containing compound functionalized with a functional group. The functional group includes a primary amine. The functionalized fluorescent dye can be mixed with a fluid to form a tracer fluid for tracing fluid flow in a subterranean formation.