Patents Examined by Arlen Soderquist
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Patent number: 12782301Abstract: A method of assessing the response of a reservoir rock to low salinity water includes obtaining a formation core sample of a reservoir rock from a reservoir. In addition, the method includes sequentially washing the formation core sample with a first series of solvents to form a first series of solvent extracts and an extracted formation core sample. Further, the method includes sequentially washing the extracted formation core sample with a second series of solvents to form a second series of solvent extracts and a cleaned formation core sample. The method also includes generating a series of mass spectra of the second series of solvent extracts. The relative abundance of the catecholamine-type structures (CTS) is determined using the series of mass spectra. Still further, the method includes subjecting the formation core sample to analysis by X-ray diffraction to generate a diffraction pattern. The relative abundance of kalonite is determined using the diffraction pattern.Type: GrantFiled: December 1, 2021Date of Patent: November 3, 2026Assignee: BP CORPORATION NORTH AMERICA INC.Inventors: Huang Zeng, Christianne Clare Wicking, Nathalia Tessarolo, John William Couves, Ian Ralph Collins
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Patent number: 12782362Abstract: The present invention provides improved cleavable biotin-containing isobaric tags for quantitative mass spectrometry proteomics, particularly useful in quantification of post-translational modifications (PTMs) and assessing cysteine containing proteins. The isobaric chemical tags, DiLeu-Biotin-Azide (DBA), consist of three “modules”: (1) a DiLeu reporter group for relative quantification using MS/MS; (2) a biotin moiety for selective enrichment via streptavidin beads; and (3) an azide functional group to enable biorthogonal click chemistry. The DBA tags could be used in a high-throughput quantitative pan-PTM analysis platform.Type: GrantFiled: June 14, 2023Date of Patent: November 3, 2026Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATIONInventors: Lingjun Li, Miyang Li, Min Ma
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Patent number: 12779460Abstract: An apparatus includes a housing including a hollow inside; a cover configured to cover the housing and support a portion of a biological cell on the cover; an opening formed through the cover and configured to expose at least a portion of the cell to the hollow inside of the housing; an electrode base disposed on a bottom of the housing; and one or more electrode rods arranged between the electrode base and the cover, and configured to support the cover, wherein the electrode base and/or the one or more electrode rods are arranged for sensing an electrical signal from at least another portion of the cell.Type: GrantFiled: May 16, 2023Date of Patent: November 3, 2026Assignee: Samsung Electronics Co., Ltd.Inventors: Jaechun Lee, Kitae Park, Chisung Bae
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Patent number: 12782243Abstract: An automated computer-controlled sampling system and related methods for collecting, processing, and analyzing agricultural samples for various chemical properties such as plant available nutrients. The sampling system allows multiple samples to be processed and analyzed for different analytes or chemical properties in a simultaneous concurrent or semi-concurrent manner. Advantageously, the system can process soil samples in the “as collected” condition without drying or grinding. The system generally includes a sample preparation sub-system which receives soil samples collected by a probe collection sub-system and produces a slurry (i.e. mixture of soil, vegetation, and/or manure and water), and a chemical analysis sub-system which processes the prepared slurry samples for quantifying multiple analytes and/or chemical properties of the sample. The sample preparation and chemical analysis sub-systems can be used to analyze soil, vegetation, and/or manure samples.Type: GrantFiled: May 3, 2024Date of Patent: November 3, 2026Assignee: Precision Planting LLCInventors: Todd Swanson, Dale Koch, Hayden Splechter, Timothy Schaefer
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Patent number: 12768834Abstract: An absorbent biogenic composition includes a mixture of a base material, a plant-based oil, and a plant-based pH indicator.Type: GrantFiled: August 8, 2025Date of Patent: October 20, 2026Assignee: Petfive Brands Holding LLCInventors: Pedro Eduardo Stevens Bastos, Gustavo Tallia Loducca, Isadora Duarte Sabater
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Patent number: 12761213Abstract: In certain embodiments, the present invention provides methods of identifying and treating a transplant recipient patient having transplantation tolerance induced by apoptotic donor leukocytes infused under cover of transient immunotherapy.Type: GrantFiled: April 16, 2020Date of Patent: October 13, 2026Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTAInventors: Bernhard J. Hering, Sabarinathan Ramachandran, Amar Singh
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Patent number: 12761221Abstract: The invention is in the field of coagulation diagnostics and relates to a method for detecting lupus anticoagulant.Type: GrantFiled: February 15, 2022Date of Patent: October 13, 2026Assignee: SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBHInventors: Norbert Zander, Carina Gerlach, Michael Timme, Regina Gebauer
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Patent number: 12761181Abstract: A field effect transistor, FET, gas sensor device (100) arranged to sense gas, and a method of sensing gas by a FET gas sensor device, are provided. The FET gas sensor device comprises at least one gate (110a, 110b), a source (120), a drain (130), and a semiconductor channel (140). The semiconductor channel and the gate(s) form a FET channel-gate coupling (150) by which an applied gate potential is arranged to control a current flowing through the semiconductor channel. The FET gas sensor device further comprises space(s) (200) arranged between the gate(s) and the semiconductor channel and configured to receive gas, whereby received gas is arranged to influence electrical property(ies) of the FET channel-gate coupling, and wherein the FET gas sensor device is arranged to sense gas based on the influenced electrical property(ies) of the FET channel-gate coupling.Type: GrantFiled: June 14, 2023Date of Patent: October 13, 2026Assignee: SWESENSI ABInventors: Zhen Zhang, Qitao Hu
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Patent number: 12760351Abstract: A biological indicator includes: a BI housing; a germinant container inside the BI housing and housing a germinant composition; a germinant releaser configured to release the germinant composition from the germinant container; a germinant releaser support supporting the germinant releaser and configured to bring the germinant releaser into contact with the germinant container upon application of a force to the germinant releaser support or the germinant container; a first spore carrier inside the BI housing, the first spore carrier having a plurality of spores deposited at a first surface thereof; and an imaging window at a first surface of the BI housing. A BI reader is configured to detect and quantify the presence of live spores in the BI, and includes an excitation source, a camera for capturing images of the spores over time, and a processor for analyzing the images to determine the presence of live spores.Type: GrantFiled: April 4, 2023Date of Patent: October 13, 2026Assignee: STERITEC PRODUCTS MFG. CO., INC.Inventors: Adrian Ponce, Kok-Hwee Ng, Darshan Yeliyur Siddegowda, Jenna Zimmerman, Dat Nguyen, Mitchell London, Jake Douglas Knickerbocker, Edward Macleod Perkins, Robert G. Waarts
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Patent number: 12754181Abstract: Embodiments of the present disclosure include methods and systems for detecting the presence of endotoxins in filters. For example, embodiments of the present disclosure are directed to methods and systems for improving in-process controls by detecting undesirable quantities of endotoxins in filters containing naturally-sourced materials prior to using those filters in the production of formulated drug substances.Type: GrantFiled: May 26, 2022Date of Patent: October 6, 2026Assignee: Regeneron Pharmaceuticals, Inc.Inventors: Nathan Mao, Annamarie Cruz, Bernhard Schilling, Scott Carver
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Patent number: 12699070Abstract: Systems and methods for a treatment of chemical sensors placed in a wellbore. A method may comprise providing a chemical sensor disposed in a sensing chamber, wherein the chemical sensor is on an optical fiber installed in a wellbore; optically interrogating the chemical sensor with the optical fiber; and pumping a treatment fluid through a fluid supply line and into the sensing chamber.Type: GrantFiled: April 26, 2022Date of Patent: August 4, 2026Assignee: Halliburton Energy Services, Inc.Inventors: John Laureto Maida, Jr., Michel Joseph Leblanc, Neal Gregory Skinner
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Patent number: 12656352Abstract: In the present invention, among blood metabolites, amino acids, organic compounds and oxylipins that were statistically significantly differentiated from the control group, were selected from type 2 diabetes patients. Specifically, asparagine, aspartic acid, glutamic acid, cysteine, lysine, citric acid, and uric acid, and 12-oxo ETE, 15-oxo ETE, 9-oxo ODE, and 20-carboxy leukotriene B4, which are oxylipins, were confirmed to have cutoff values of AUC>0.7. In addition, the blood metabolites showed a significant difference between a DME patient group and a non-DME patient group, and thus were confirmed to be usable for accurate diagnosis of DME.Type: GrantFiled: May 6, 2021Date of Patent: June 16, 2026Assignees: KONKUK UNIVERSITY INDUSTRIAL COOPERATION CORPORATION, UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITYInventors: Choon-Hwan Lee, Jeong-Taek Woo, Sang-Youl Rhee, Eun-Sung Jung
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Patent number: 12650381Abstract: The embodiments disclose an apparatus for testing organic plant materials for microbial contamination including machine-readable QR code identifiers associated with multiple facility testing locations, samples from each location are treated with microorganism-specific growth stimulator solutions and incubated locally in a portable incubator to accelerate microbial growth, a plurality of sensors and a camera, wirelessly coupled to a remote server, capture environmental data and images of the incubated samples, an artificial intelligence (AI) engine on the server analyzes the images and sensor data, correlates them to respective QR code identifiers, and compares them against a pattern recognition database to identify microbial contaminants, a mobile application displays AI-generated contamination reports, remediation recommendations, and a facility heat map identifying locations of recurrent infestations, a machine learning system continuously updates remediation determinations based on sensor feedback, an AI-eType: GrantFiled: July 22, 2025Date of Patent: June 9, 2026Inventor: Craig Ellins
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Patent number: 12636393Abstract: The present invention discloses an automated sterility testing assembly that has a needle holder sized and configured to selectively retain a needle fluidly coupled to a sterility testing filter. The holder is configured to move the needle in a first direction to pierce selected containers disposed on a carrier and to move the needle in a second direction opposite the first direction to remove the needle from the selected containers. The assembly includes a brace that braces the fluid containers during their respective piercings by the needle. Accordingly, the brace prevents the needle from moving the fluid containers out of the carrier.Type: GrantFiled: November 12, 2024Date of Patent: May 26, 2026Assignee: Automated Systems of Tacoma, LLCInventors: Jordan McDonald, Steven Ng, Michael Moore, Raul A. Passarini
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Patent number: 12631613Abstract: The present disclosure discloses an in situ U—Pb dating method for calcite, including: cutting a calcite sample to prepare an epoxy resin sample target; placing the sample in a laser ablation sample chamber, and adjusting a position of the sample in an optical axis direction; conducting line scanning ablation on the sample target, and measuring ion signal intensity data of 43Ca, 88Sr, 139La, and 238U; conducting two-dimensional (2D) element imaging to obtain a 2D element content distribution map; according to the 2D element content distribution map, determining a high-U analysis target area, conducting point ablation on the high-U target area, and measuring ion signal intensity data of 206Pb, 207Pb, and 238U; and after the element signal data is obtained, calculating 207Pb/206Pb and 238U/206Pb fractionation coefficients, correcting ratios of an unknown sample, constructing a Tera-Wasserbug diagram, and calculating age data and an initial Pb isotope (207Pb/206Pb) composition of the calcite sample.Type: GrantFiled: November 9, 2022Date of Patent: May 19, 2026Assignee: Institute of Geology and Geophysics, Chinese Academy of SciencesInventors: Shitou Wu, Yueheng Yang, Hao Wang, Lei Xu, Chao Huang, Liewen Xie
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Patent number: 12631654Abstract: The invention provides assays and methods for detecting and monitoring systemic inflammation. Particularly, the invention in embodiments thereof relates to the use of urinary biomarkers for non-invasive determination of the level of inflammation.Type: GrantFiled: December 10, 2020Date of Patent: May 19, 2026Assignees: ICHILOV TECH LTD., YEDA RESEARCH AND DEVELOPMENT CO. LTD.Inventors: Shani Shenhar-Tsarfaty, Shlomo Avraham Berliner, Ori Rogowski, Eyal Fisher, Adi Silberman, Yishai Levin
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Patent number: 12625141Abstract: A fluorescent dye, as well as a preparation method and uses thereof, wherein the fluorescent dye is sensitive and specific to viscosity and has low background fluorescence; it can also be used as a fluorescent activated and lighted probe used for fluorescent labeling, quantification or monitoring of protein, enzymes or nucleic acid.Type: GrantFiled: April 27, 2020Date of Patent: May 12, 2026Assignee: FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY LTDInventors: Linyong Zhu, Yi Yang, Dasheng Zhang, Xianjun Chen, Qiuning Lin, Ni Su
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Patent number: 12625123Abstract: The present invention relates to a device and a method for the analytical and/or sensory determination of the release of an active substance or several active substances from a release system. In particular, the present invention relates to a device and a method for determining the release of an active substance or active substances, in particular of an odiferous substance or flavoring or an odiferous substance or flavoring mixture, from a capsule or a precursor. Furthermore, the present invention relates to a device and a method for determining the properties of a release system, in particular of a capsule or a precursor. Ultimately, the present invention relates to the use of the device and method according to the invention for the analytical and/or sensory determination of the release of one or more active substances from a release system.Type: GrantFiled: November 27, 2019Date of Patent: May 12, 2026Assignee: SYMRISE AGInventors: Edison Diaz, Isabel Lanfermann, Katharina Michels, Marco Singer, Patrick Ostermann, Achim Schumann, Fabian Ude
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Patent number: 12618778Abstract: In a sulfur chemiluminescence detector (SCD) including a heating furnace 210 including a combustion tube 211 and a heating means 215 for heating the combustion tube 211, an inert-gas introduction tube 214 that has the front end inserted into an end portion on an inlet side of the combustion tube 211 and has the rear end into which an end portion on the outlet side of a column 140 of a gas chromatograph is inserted, and inert-gas supplying means 264, 221, and 251 for supplying inert gas into the inert-gas introduction tube 214 in a manner that the inert gas flows from the rear end to the front end are provided. The inert gas (for example, nitrogen) flowing through the inert-gas introduction tube 214 can prevent the end portion on the outlet side of the column 140 from being exposed to oxygen. In this manner, generation of column bleeding caused by a decomposition product of the liquid phase can be suppressed, so that a decrease in the sensitivity of the SCD can be suppressed.Type: GrantFiled: December 20, 2018Date of Patent: May 5, 2026Assignee: SHIMADZU CORPORATIONInventor: Takamasa Suzuki
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Patent number: 12618775Abstract: A solution is proposed for testing a luminescence imaging apparatus (105). A corresponding method (700) comprises acquiring (706) a photograph image and finding (708) a position of the testing device (110) in the photograph image. The 5method further comprises acquiring (706) a luminescence image and determining (734-736) a representation of sites of the testing device (110), each comprising at least one luminescence substance, in the luminescence image according to the position of the testing device (110) in the photograph image. The luminescence imaging apparatus (105) is then tested (754-772) according to the representation of the sites (330) in the 0luminescence image. A corresponding computer program (600) and a computer program product for implementing the method (700) are also proposed. Moreover, a testing device (110) for use in the method (700) is proposed.Type: GrantFiled: November 19, 2020Date of Patent: May 5, 2026Assignee: SurgVision GmbHInventors: Dmitry Bozhko, Maximilian Koch, Adrian Taruttis, Christian Aichinger, Jurek Nordmeyer-Massner