Patents Examined by Arlen Soderquist
  • Patent number: 12140550
    Abstract: A photoluminescent material can be applied to part of a substrate as part of substrate inspection. The photoluminescent material includes a conjugated polymer having a coiled macroscopic molecular shape and a meta-linkage or an ortho-linkage. The substrate is imaged using an inspection system. The conjugated polymer can be, for example, poly(m-phenylene ethynylene) (PPE) or poly(para-phenylene vinylene) (PPV).
    Type: Grant
    Filed: January 25, 2023
    Date of Patent: November 12, 2024
    Assignee: KLA Corporation
    Inventors: Jinsang Kim, Grace Chen
  • Patent number: 12130266
    Abstract: A jet injector for a GC that includes a body, a skirt extending away from the body; and a bore that extends through the skirt and the body to create an inlet and an outlet for the jet injector.
    Type: Grant
    Filed: May 20, 2022
    Date of Patent: October 29, 2024
    Assignee: AGILENT TECHNOLOGIES, INC
    Inventors: Edward D. Mroz, Heng He
  • Patent number: 12130295
    Abstract: Disclosed are methods and systems to determine a subject's metabolic vulnerability index (MVX) score using at least one defined mathematical model of risk. The methods comprise evaluating various biomarkers to distinguish various health risks. In one embodiment, the method comprises evaluating biomarkers to determine a relative risk of premature all-cause mortality. The model may include NMR-derived measurements of GlycA, S-HDLP, branched chain amino acids (BCAAs), ketone bodies, total serum protein, and citrate in at least one biosample of the subject.
    Type: Grant
    Filed: October 22, 2021
    Date of Patent: October 29, 2024
    Assignee: LipoScience, Inc.
    Inventors: James D. Otvos, Irina Y. Shalaurova
  • Patent number: 12130236
    Abstract: What is disclosed is a method for creating a database for determining a virtual reference value for a light transmission aggregometry measurement, comprising the following steps: a. providing platelet-rich plasma “PRP” (17) of a reference blood sample; b. performing a light transmission measurement with a first light wavelength and a second light wavelength (14), different from the first, on the PRP (17) of the reference blood sample; c. providing platelet-poor plasma “PPP” of the reference blood sample; d. performing a light transmission measurement on the PPP in order to determine a PPP reference value; e. assigning the measurement result of step d to the measurement results of step b in a database; f. repeating steps a to e for a plurality of reference blood samples. The database obtained using this method makes it possible to determine a virtual reference value that is an excellent estimate of the PPP reference value.
    Type: Grant
    Filed: July 22, 2022
    Date of Patent: October 29, 2024
    Assignee: Kommanditgesellschaft Behnk Elektronik GmbH & Co.
    Inventor: Christian Radon
  • Patent number: 12123884
    Abstract: An automatic analyzer is capable of normally maintaining a device condition and exhibiting a stable performance by automatically monitoring a cleaning implementation situation using a wash rack. The automatic analyzer includes an analysis unit, a rack loading unit into which at least a sample rack that holds the sample and a wash rack that holds a cleaning liquid are loaded. A transportation mechanism transports the sample rack and the wash rack to the analysis unit. A management control unit causes the wash rack to be transported to an analysis unit, causes a cleaning operation of the analysis unit by the cleaning liquid held by the wash rack, and causes stopping of the sample analysis operation of the analysis unit to which the wash rack has been transported until a performance of the analysis unit is determined to be normal based on the cleaning operation.
    Type: Grant
    Filed: November 14, 2019
    Date of Patent: October 22, 2024
    Assignee: HITACHI HIGH-TECH CORPORATION
    Inventors: Kenichi Yagi, Masafumi Miyake, Sayaka Asada
  • Patent number: 12117424
    Abstract: A jet injector for a GC that includes a body, a skirt extending away from the body; and a bore that extends through the skirt and the body to create an inlet and an outlet for the jet injector.
    Type: Grant
    Filed: January 13, 2020
    Date of Patent: October 15, 2024
    Assignee: AGILENT TECHNOLOGIES, INC.
    Inventors: Edward D. Mroz, Heng He
  • Patent number: 12111327
    Abstract: The automatic analyzer is capable of performing other operations concurrently with a maintenance operation and notifying a user when a user action is required in executing maintenance and displaying guidance. Automatic analyzer includes analysis modules and that analyze a sample, a display device that displays information related to maintenance in the analyzer including the analysis modules and, and an overall management computer that controls a constant display area to be displayed on a display screen of the display device, in which when there is a need to notify a user of a maintenance status at a timing when the maintenance in the analyzer is executed in a background and a screen other than a maintenance screen is displayed on the display device, the overall management computer displays notification information on the screen including global areas and of the display device.
    Type: Grant
    Filed: November 13, 2019
    Date of Patent: October 8, 2024
    Assignee: HITACHI HIGH-TECH CORPORATION
    Inventors: Satoru Chida, Masashi Akutsu, Chikook Ha, Satoshi Yokotsuka
  • Patent number: 12085560
    Abstract: Provided is a biochemical reaction substrate which can achieve higher test sensitivity and shorter testing time in an allergy test, which can also reduce a required amount of blood or the like needed as a specimen and decrease the number of test steps, thereby facilitating performance of the test, and which is to be used in an allergy test in which infection risk of the test staff is reduced.
    Type: Grant
    Filed: February 1, 2019
    Date of Patent: September 10, 2024
    Assignee: NIPPON CHEMIPHAR CO., LTD.
    Inventors: Kenji Uemura, Norio Tanimoto, Mai Egami, Takahiro Mataki, Yumi Konishi, Motoe Shimizu, Shigenori Takahashi, Koji Sakaguchi
  • Patent number: 12070745
    Abstract: A separation container for extracting a portion of a sample for use or testing and method for preparing samples for downstream use or testing are provided. The separation container may include a body defining an internal chamber. The body may define an opening, and the body may be configured to receive the sample within the internal chamber. The separation container may further include a seal disposed across the opening, such that the seal may be configured to seal the opening of the body, and a plunger movably disposed at least partially inside the internal chamber. The plunger may be configured to be actuated to open the seal and express the portion of the sample.
    Type: Grant
    Filed: June 30, 2022
    Date of Patent: August 27, 2024
    Assignee: BIOMERIEUX, INC.
    Inventors: Christopher S. Ronsick, Mark S. Wilson, John D. Walsh
  • Patent number: 12061194
    Abstract: Embodiments described herein may be useful in the detection of analytes. The systems and methods may allow for a relatively simple and rapid way for detecting analytes such as chemical and/or biological analytes and may be useful in numerous applications including sensing, food manufacturing, medical diagnostics, performance materials, dynamic lenses, water monitoring, environmental monitoring, detection of proteins, detection of DNA, among other applications. For example, the systems and methods described herein may be used for determining the presence of a contaminant such as bacteria (e.g., detecting pathogenic bacteria in food and water samples which helps to prevent widespread infection, illness, and even death). Advantageously, the systems and methods described herein may not have the drawbacks in current detection technologies including, for example, relatively high costs, long enrichment steps and analysis times, and/or the need for extensive user training.
    Type: Grant
    Filed: December 8, 2021
    Date of Patent: August 13, 2024
    Assignee: Massachusetts Institute of Technology
    Inventors: Timothy Manning Swager, Hadley Sikes Johnson, Qifan Zhang, Eric Alexander Miller, Lukas Zeininger, Ki-Joo Sung, Kosuke Yoshinaga
  • Patent number: 12000853
    Abstract: An automated computer-controlled sampling system and related methods for collecting, processing, and analyzing agricultural samples for various chemical properties such as plant available nutrients. The sampling system allows multiple samples to be processed and analyzed for different analytes or chemical properties in a simultaneous concurrent or semi-concurrent manner. Advantageously, the system can process soil samples in the “as collected” condition without drying or grinding. The system generally includes a sample preparation sub-system which receives soil samples collected by a probe collection sub-system and produces a slurry (i.e. mixture of soil, vegetation, and/or manure and water), and a chemical analysis sub-system which processes the prepared slurry samples for quantifying multiple analytes and/or chemical properties of the sample. The sample preparation and chemical analysis sub-systems can be used to analyze soil, vegetation, and/or manure samples.
    Type: Grant
    Filed: January 7, 2021
    Date of Patent: June 4, 2024
    Assignee: Precision Planting LLC
    Inventors: Todd Swanson, Dale Koch, Hayden Splechter, Timothy Schaefer
  • Patent number: 11988608
    Abstract: A method for determining the presence of an acidic sulfide species in a liquid sample of an industrial or environmental material. The method includes the step of contacting the sample or an extract thereof with a composition including a metal complex dye compound in which the electromagnetic absorption spectrum of the metal complex dye compound changes upon reaction with an acidic sulfide species.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: May 21, 2024
    Assignee: INNOSPEC LIMITED
    Inventor: Philip Maltas
  • Patent number: 11988601
    Abstract: A method and process for determining the propensity of elastomeric articles to discolor or stain is provided. The elastomeric articles tested are generally crosslinked elastomeric articles containing accelerators, such as carbamates. Residual carbamates can cause staining when contacted with metal ions, such as copper. Tests are disclosed for determining the propensity of the elastomeric articles to stain or discolor. The process can include remediation steps for preventing future articles from staining.
    Type: Grant
    Filed: June 8, 2020
    Date of Patent: May 21, 2024
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Priyadarshini Gadgil, Alison S. Bagwell, Maurice Thompson, Zamsari Bin Zakaria, Sumsuriya Beraheng
  • Patent number: 11982667
    Abstract: Provided is a platelet aggregation capacity analyzer including a blood coagulation system-analyzing unit that analyzes a platelet aggregation capacity based on measurement data during a coagulation process of a platelet-containing sample, and an output control unit that controls an output of results analyzed by the blood coagulation system-analyzing unit, in which the blood coagulation system-analyzing unit analyzes the platelet aggregation capacity of the platelet-containing sample based on the barb of measurement data during the coagulation process with a platelet aggregation inhibitor added to the platelet-containing sample and measurement data during the coagulation process without a platelet agonist or the platelet aggregation inhibitor added to the platelet-containing sample.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: May 14, 2024
    Assignee: SONY CORPORATION
    Inventors: Aya Fuchigami, Seungmin Lee, Yoshihito Hayashi, Kenzo Machida
  • Patent number: 11971392
    Abstract: The present disclosure describes a field flow fractionator (FFF). In an embodiment, the FFF includes a spacer including a core, and a coating covering the core. In an embodiment, the FFF includes a spacer including a core, and a coating covering the core, a bottom block including pins, and a top block including mating holes to receive the pins, where the spacer is configured to be positioned between the top block and the bottom block. In an embodiment, the FFF includes a spacer including a core including an opening, a top side, and a bottom side, a first coating covering the top side, and a second coating covering the bottom side, a top block configured to press on the first coating along a first periphery of the opening, and a bottom block configured to press on the second coating along a second periphery of the opening.
    Type: Grant
    Filed: June 25, 2020
    Date of Patent: April 30, 2024
    Assignee: Wyatt Technology, LLC
    Inventors: Steven P. Trainoff, Jeremy W. Jarrett
  • Patent number: 11971427
    Abstract: Provided is an automated analysis device capable of a more accurate determination of the sizes of bubbles included in a liquid. The automated analysis device includes a detection unit which detects bubbles included in a liquid, an internal standard solution syringe which executes a first liquid supply operation in which a liquid is supplied via the detection unit, a diluent syringe, a sipper syringe, solenoid valves, and a control device which determines whether the size of the bubbles detected during the first liquid supply operation is normal or not based on the operation speed of the liquid supply unit, and controls the operation of the liquid supply unit according to the determination.
    Type: Grant
    Filed: March 10, 2020
    Date of Patent: April 30, 2024
    Assignee: HITACHI HIGH-TECH CORPORATION
    Inventors: Akinao Fujita, Takushi Miyakawa, Tetsuji Kawahara
  • Patent number: 11959046
    Abstract: A method of creating a protective coating on an alkali metal hydroxide-containing solid is provided. The method includes providing carbon dioxide to an alkali metal hydroxide-containing solid and allowing the alkali metal hydroxide and carbon dioxide to react thereby forming a carbonate or bicarbonate-containing layer on the exterior of the solid wherein the carbonate or bicarbonate-containing layer is non-hygroscopic and water soluble, and wherein greater than 80% of the hydroxide in the hydroxide-containing solid does not react with the carbon dioxide, and further wherein the alkali metal hydroxide-containing solid is substantially free of lithium hydroxide. A method of testing for the presence of carbonate-containing coating on an alkali metal hydroxide containing solid is also provided. The method includes exposing the coated solid to 95 weight percent ethanol, collecting the ethanol effluent and testing the effluent for alkali metal hydroxide.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: April 16, 2024
    Assignee: ECOLAB USA INC.
    Inventors: Kim R. Smith, Mark P. Peterson, Keith E. Olson
  • Patent number: 11953444
    Abstract: Disclosed are a zero-power detecting sensor of a chemical substance and a sensing method. As light is irradiated to the detecting sensor including a graphene, a light absorbing layer, and an electrode stacked, the chemical substance is detected without power.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: April 9, 2024
    Assignee: Korea University Research and Business Foundation
    Inventors: Chulho Lee, Haeli Park
  • Patent number: 11953486
    Abstract: The present invention relates to a sensor (1) for sensing organic carbon in a liquid (L), comprising: a container (2) having an interior space (20) for receiving the liquid (L), a photodetector (3), and a light source (4) configured to emit ultraviolet light (5) so that the ultraviolet light (5) travels along an optical path (P) through liquid (L) residing in the interior space (20) and is absorbable by carbon bonds of organic molecules in the liquid (L).
    Type: Grant
    Filed: July 19, 2020
    Date of Patent: April 9, 2024
    Assignee: SENSIRION AG
    Inventors: Raffaele Di Giacomo, Matthias Streiff, Michael Merz, Nicolas Moeller
  • Patent number: 11946278
    Abstract: A cuvette for treating and characterizing water via ultrasonic waves and optical measurements comprises at least one ultrasonic transducer for treating said water by introducing at least one ultrasonic pulse into the water. The at least one ultrasonic pulse either varies parameters of the water, and/or moves and repositions particles within the water. The cuvette further comprises a spectrometry device for measuring spectral components of light and at least one light source for irradiating the water with irradiation light.
    Type: Grant
    Filed: August 6, 2019
    Date of Patent: April 2, 2024
    Assignee: MAYTRONICS LTD.
    Inventors: Alex Rachman, Ben Lewis, Shay Peretz