Abstract: A coated granule, a solid dispersion, a composition, and a preparation for oral masking, which improve the taste masking effect of vortioxetine hydrobromide, and improve the patient adherence and compliance.

Abstract: A spreading device, a powder-like mixture composition and a method tor spreading the composition for control or prevent forest pathogens on tree stumps are disclosed.

Abstract: The present technique pertains to a method of preparation of a succinylated collagen-fibrinogen hydrogel and a succinylated collagen-fibrinogen hydrogel prepared thereby. The method of preparation of a succinylated collagen-fibrinogen hydrogel according to the present technique can produce a collagen-based bio-substance in a simple process, wherein collagen can be prevented from being entangled and an improvement can be brought about in hydrophilicity, cell growth rate, cell compatibility, and cell diffusion capability, whereby the collagen-based bio-substance exhibits excellent biocompatibility in vivo.

Abstract: The present invention relates to a two-stage sintering method for preparing a porous biphasic calcium phosphate ceramic from calcium-containing biological waste, wherein hydroxyapatite prepared from calcium-containing waste is mixed with a foaming agent to prepare a bone graft material having medicinal use through two-stage sintering.

Abstract: A method of producing a multi-layered functionalised graphene oxide paper, comprises the steps of providing an aqueous suspension of oxidised graphene oxide flakes, size reducing the oxidised graphene oxide flakes in the suspension to provide an aqueous suspension of particulate oxidised graphene oxide having an average particle size of less than 1 ?m and drying the aqueous suspension in a vessel to provide a multi-layered graphene oxide material. The multi-layered graphene oxide material is annealed to provide a multi-layered reduced graphene oxide material, before surface grafting functional groups to the surface of the multi-layered reduced graphene oxide material by reacting the material with a functional group precursor in the presence of plasma. The use of a graphene oxide material to treat bone defects, and as an energy storage device, is also described.

Abstract: Disclosed is method for the preparation of an amylose/carotenoid complex including the steps of a) heating a first composition in powder form including amylose or one of its derivatives, so that this amylose changes to amorphous form; and b) mixing the first composition obtained at the end of step a) with a second composition in powder form including at least one carotenoid-type pigment so as to enable the heating of the mixture between 30 and 70° C. to allow the passage to the V conformation of the amylose or one of its derivatives during the complexation of the latter with the carotenoid type pigment, until a homogeneous powders mixture is obtained; compositions which can be obtained by such a method as well as the use of such compositions in the fields of printing, writing, tattooing or make-up.

Abstract: Printed delivery devices are disclosed herein. The printed delivery devices may include a layer formed from a water-soluble, printable composition. The water-soluble, printable composition may include purified water, pullulan, and vegetable glycerin. The printed delivery device may also include a support substrate made from polyester and/or polyolefin. The first layer may be printed on the support substrate.

Abstract: The present disclosure relates to amine hydrofluorides and mixtures of these amine hydrofluorides, and to a process for the preparation of these amine hydrofluorides and their use in oral hygiene compositions.

Abstract: An ibuprofen controlled-release tablet and a method for preparing same are provided. The controlled-release tablet is composed of a drug-containing immediate-release layer and a drug-containing sustained-release layer, wherein a mass of ibuprofen in the drug-containing sustained-release layer is greater than a mass of ibuprofen in the drug-containing immediate-release layer, and a ratio of the mass of the ibuprofen in the drug-containing sustained-release layer to the mass of the ibuprofen in the drug-containing immediate-release layer is ?7. The tablet of the present disclosure has an effective analgesic effect for 24 h after administration.

Abstract: A high dose rapidly dispersing three-dimensionally printed dosage form comprising a high dose of water soluble drug in a porous matrix that disperses in water within a period of less than about 15 seconds is disclosed. Also disclosed are methods of preparing the dosage form and of treating a condition, disease or disorder that is therapeutically responsive to the drug.

Abstract: The present invention is directed to methods of treating nasal and/or ophthalmic diseases, symptoms, or disorders that are therapeutically responsive to corticosteroid therapy by delivering aqueous solution formulations comprising a corticosteroid to nasal and ophthalmic tissues. The invention is also directed to methods, systems, devices, and compositions for delivering aqueous solution formulations comprising a corticosteroid and an antihistamine to nasal and ophthalmic tissues.