Abstract: Described herein are methods, devices, and systems that identify ventricular sensed (VS) events from a signal indicative of cardiac electrical activity, such a far-field EGM or ECG signal, and monitor for an arrythmia and/or perform arrythmia discrimination based on the VS events. Beneficially, such embodiments reduce the probability of double-counting of R-wave, or more generally, of oversensing VS events, and thereby provide for improved arrythmia detection and arrythmia discrimination.

Abstract: The present invention relates to a system and method, in which a distal end of an electrode is implanted in an organ, such as a pituitary gland, for intermittent electrical stimulation thereof and a proximal end of the electrode is provided with a connection plug, a distal end of which can be attached to a bone adjacent the organ, such an anterior wall of the sphenoid sinus/vomer, and a proximal end of which can be reversibly connected electrically to a wire that is connected electrically to a source of electrical stimulation for the organ.

Abstract: A system and method is provided for improving the patient outcome for a subject having an aneurysm. The method includes determining that the subject has the aneurysm, positioning a vagus nerve stimulation system on the subject, the vagus nerve stimulation system being configured to provide an electrical stimulation to the vagus nerve of the subject. Stimulating the vagus nerve of the subject with the vagus nerve stimulation system to at least one of: prevent further growth of the aneurysm; decrease the likelihood that the aneurysm ruptures; and decrease effects of rupture, when the aneurysm of the subject ruptures.

Abstract: A wearable blood analyte measurement device includes a casing defining an appendage-receiving bore and having an interior volume. A plurality of magnets is within interior volume. The magnets produce a magnetic field in the bore. A nuclear magnetic resonance (NMR) transceiver is supported by the casing and positioned to emit radiofrequency (RF) pulses to and receive NMR signals from the bore. An electronics assembly is within the interior volume and in communication with the NMR transceiver. A power source is in the interior volume and powers the NMR transceiver and the electronics assembly.

Abstract: A device comprises a treatment system to treat scalp or hair; one or more sensors configured to detect at least one spatial condition selected from device contact with scalp or hair, device distance to scalp or hair, and device location in relation to scalp or hair; a controller configured to send instructions to adjust the treatment system based on the detected spatial condition of the device.

Abstract: Apparatus and techniques described herein can include delivery of a surgical laser beam for tissue excision or to facilitate hemostasis. The surgical laser beam can be generated, for example, using an ultrafast laser source. Such an approach can provide non-invasive treatment in relation to, for example, aerodigestive anatomy, such as for treatment of laryngeal, oropharyngeal, bronchial, and oral cavity tissues. Other generally available laser sources and their associated treatments may present various drawbacks making them less suitable for treatment for laryngeal, pharyngeal or bronchial pathologies, and use of the apparatus and techniques described herein can address such drawbacks.

Abstract: A Circadian Rhythm Monitoring and Regulation (CMR) system and method that includes: a novel non-obtrusive wearable system for increasing the health and productivity of warfighters or other individuals that are disrupted by excessive, abnormal shifts in work or flights across multiple time zones. The CMR system is based on advanced sensor and software technology and models of human circadian system phototransduction and a circadian stimulator oscillator developed by applicants. It measures circadian misalignment and provides lighting suggestions for circadian rhythm maintenance and realignment.

Abstract: In some examples, a laser-based ophthalmological surgical system (hereinafter “system”) includes a therapeutic radiation source configured to emit therapeutic radiation at a first intensity during a therapeutic portion and to emit probe radiation with a second intensity which is less than the first intensity during a probe portion. The system may also include one or more optical elements configured to direct the therapeutic portion and the probe portion into an eye of a patient and to collect reflected radiation from the eye of the patient. The reflected radiation may be indicative of dynamics of microbubbles in the cells of the eye of the patient.

Abstract: A method for treating a subject is provided. The method includes performing surgery on the subject such as, for example, a carotid endarterectomy. Light therapy is administered to the subject as an adjuvant to the surgery.

Abstract: A system and method of displaying neonatal health information are disclosed. In one aspect, the method includes receiving data characterizing a start of an APGAR timer; receiving a time value associated with a current time of the APGAR timer; receiving and displaying on an electronic display a plurality of time windows and a corresponding plurality of target values, each of the plurality of target values representing a predetermined blood oxygen threshold value in connection with a corresponding one of the plurality of time windows; receiving and displaying on an electronic display a measured blood oxygen level value; and highlighting, on the electronic display, a first of the plurality of target values and a corresponding first of the plurality of time windows when the time value associated with the current time of the APGAR timer reaches a first time value.

Abstract: The invention is directed to a light source device comprising a light emitting element for emitting a blue light having a wavelength ranging from 435 to 500 nm, the light source device being configured to provide the blue light to at least one cell at a transmitted fluence ranging from 0.01 to 18. J/cm2 to promote or induce growth and proliferation of the cell and wherein the light emitting element has a power density ranging from 0.05 to 30 mW/cm2. The invention is also directed to a light source assembly comprising a product adapted to be in contact with the skin or a wound and a light source device connected to the product for providing blue light to at least one skin cell, preferably of the wound.

Abstract: A lighting arrangement for providing visible light and radiation in another spectrum that is medically beneficial is provided. The lighting arrangement comprises a light source adapted to emit visible light; a radiation source adapted to emit radiation in a predetermined spectrum, and a driver circuit adapted to provide a first driving current that is pulsed and has a duty cycle of not greater than 20%. The predetermined spectrum is preferably in the range 760-1400 nm. The lighting arrangement is adapted to provide the first driving current to the radiation source but not the light source. Corresponding method and products employing such lighting arrangement are also provided.

Abstract: A medical marking device, consisting of a radiotransparent plate having a first plurality of radiopaque elements embedded therein in a first predefined pattern and a second plurality of optical reflectors positioned on a surface in proximity to the plate in a second predefined pattern. The device also includes a sigmoid mounting arm having a first end connected to the radiotransparent plate and a second end containing one or more fastening receptacles.

Abstract: According to an embodiment of the present disclosure, a light outputting device for scalp care includes a dome-shaped outer case defining an appearance, an inner case formed inside the outer case, and a plurality of light sources disposed in a space between the outer case and the inner case, wherein the plurality of light sources include a plurality of first laser light sources, and the optical outputting device includes a plurality of light guide mechanisms arranged corresponding to the plurality of first laser light sources to distribute laser light emitted from the first laser light sources apply the laser light toward the inner case.

Abstract: A non-invasive continuous blood sugar level monitoring apparatus integrated with a real-time health support system. The blood sugar levels and other vital physiological information of the user can also be tracked wirelessly through the apparatus. The apparatus has an integrated real-time alert and reminder feature for notifying the user during medication and unusual physiological conditions. An automated diet and lifestyle recommendation solution is integrated into the device to help the user maintain healthy blood sugar and blood pressure levels. The low-powered the telemetry device is used for communicating the stored physiological information of the user and the computed results between the network of devices.

Abstract: Aligner systems and methods including a sequence of aligners having energy-delivering elements. For example, first and second aligners of the sequence of aligners may include first and second polymer shells that have shapes for applying respective first and second local forces to first and second regions of a dental arch to move one or more first teeth and one or more second teeth, respectively. The first and second aligners may also include corresponding first and second heating elements that are arranged to heat first and second target regions of the dental arch associated with moving the one or more first teeth and one or more second teeth, respectively. Heat energy from the first and second heating elements may improve an outcome of respective first and second stages of a treatment plan.

Abstract: Apparatus and techniques described herein can include delivery of a surgical laser beam for tissue excision or to facilitate hemostasis. The surgical laser beam can be generated, for example, using an ultrafast laser source. Such an approach can provide non-invasive treatment in relation to, for example, aerodigestive anatomy, such as for treatment of laryngeal, oropharyngeal, bronchial, and oral cavity tissues. Other generally available laser sources and their associated treatments may present various drawbacks making them less suitable for treatment for laryngeal, pharyngeal or bronchial pathologies, and use of the apparatus and techniques described herein can address such drawbacks.

Abstract: Systems, eye-mountable devices, and methods that facilitate chronotherapeutic treatment of primary open-angle glaucoma are provided which enable therapeutic products to be delivered to the eye in a controlled manner only when desired. According to one embodiment, an eye-mountable device comprises a substrate having an eye-mounting surface for positioning on an eye of a patient, a sensor that obtains a plurality of measurements representative of a condition of the eye of the patient over a period of time, a therapeutic agent delivery assembly coupled, and a processor for executing a temporal model of a therapeutic agent delivery in communication with the sensor and the therapeutic agent delivery assembly. The processor receives the plurality of measurements and activates the therapeutic agent delivery assembly to administer a first amount of a drug to the eye of the patient based on the temporal model associated with the plurality of measurements.

Abstract: The present disclosure describes a sleep staging system. The sleep staging system comprising: one or more sensors configured to generate output signals conveying information related to one or more breathing parameters of subject; and one or more physical computer processors operatively connected with the one or more sensors, the one or more physical computer processors configured by computer readable instructions to: determine, based on the output signals, one or more breathing features of individual breaths of the subject; determine a distribution of the one or more breathing features over one or more time windows; detect presence of a breathing event based on the output signals; determine sleep states of the subject with a sleep stage classifier model based upon the distribution of the breathing features and the one or more breathing events; and provide feedback indicating the sleep states.

Abstract: A catheter system for treating a treatment site within or adjacent to a blood vessel within a body of a patient, the treatment site having a proximal region and a distal region, includes an energy source, a guide shaft, and an energy guide. The energy source generates energy. The guide shaft is positionable adjacent to the treatment site. The energy guide receives energy from the energy source. The energy guide is movably coupled to the guide shaft. The energy guide includes a guide distal end that is configured to be positioned adjacent to the treatment site. The guide distal end of the energy guide is selectively movable relative to the guide shaft and adjacent to and between the proximal region and the distal region of the treatment site while the energy guide receives energy from the energy source.