Abstract: Phytosanitary composition for use especially in affording protection to plants from undesirable plant species. The composition is characterized in that it contains at least one benzamidic compound associated with at least one cyclodextrine to improve mobility in the ground and/or the biological afficacy of the benzamidic derivative. The invention also concerns a method of preparing the phytosanitary composition.
Abstract: There is disclosed a herbicidal composition containing (a) 2-?4-chloro-2-fluoro-5-(n-pentyloxycarbonylmethoxy)phenyl!-4,5,6,7-tetrahy dro-2H-isoindole-1,3-dione and (b) at least one selected from the group consisting of N-(phosphonomethyl)glycine, (2-amino-4-methylphosphinobutyryl)alanylalanine, DL-homoalanin-4-yl(methyl)phosphinic acid and salts thereof. Also disclosed is a method for controlling undesired weeds by application of the herbicidal composition.
Abstract: The invention also concerns a method of selectively inducing terminal differentiation of neoplastic cells and thereby inhibiting proliferation of such cells which comprises contacting the cells under suitable condition with an amount of the compound effect to selectively induce terminal differentiation.Moreover, the invention provides a method of treating a patient having a tumor characterized by proliferation of neoplastic cells which comprises administering to the patient an amount of the compound effective to selectively induce terminal differentiation of such neoplastic cells, thereby inhibiting their proliferation and suppressing oncogenicity.Lastly, the present invention provides a pharmaceutical composition comprising a pharmaceutically acceptable carrier and the compound in an amount effective less than an amount which would cause toxicity in the patient.
Type:
Grant
Filed:
June 7, 1995
Date of Patent:
September 16, 1997
Assignees:
The Trustees of Columbia University in the City of New York, Sloan-Kettering Institute for Cancer Research
Inventors:
Ronald Breslow, Paul A. Marks, Richard A. Rifkind
Abstract: A novel process is described for controlling sprouting in potato tubers by exposure of the tubers to an effective amount of anisic acid, coumaric acid, gallic acid, or mixtures thereof.
Type:
Grant
Filed:
July 26, 1995
Date of Patent:
June 3, 1997
Assignee:
The United States of America as represented by the Secretary of Agriculture
Inventors:
Edward C. Lulai, Paul H. Orr, Martin T. Glynn
Abstract: Herbicidal compositions containing 4-benzoylisoxazole compounds and antidotal compounds therefor to reduce injury to various crops, particularly corn, from the phytotoxic effects of 4-benzoylisoxazole herbicides when used alone or in combination with additional pesticidally active ingredients. Methods for reducing phytotoxicity or injury to crop plants, particularly corn crops, due to 4-benzoylisoxazole herbicides are also described.
Abstract: A method of treating a mammal with a neurodegenerative disease which is caused at least in part by the neurotoxic effects of the .beta.-amyloid protein. This method constitutes administering a metabotropic receptor agonist to such a mammal. In particular, the agonist trans-ACPD or 1S,3R-ACPD can be administered intravenously to treat a mammal with Alzheimer's disease.
Type:
Grant
Filed:
April 7, 1995
Date of Patent:
April 22, 1997
Assignee:
Cortex Pharmaceuticals, Inc.
Inventors:
David D. Eveleth, Judith A. Kelleher, Carl W. Cotman
Abstract: The invention provides compounds, several of which belong to a class having two or more nonpolar components connected by a polar group and having polar groups on the termini of the compound.The invention also concents a method of selectively inducing termini differentiation of neoplastic cells and thereby inhibiting proliferation of such cells which comprises contacting the cells under suitable condition with an amount of the compound effect to selectively induce terminal differentiation.Moreover, the invention provides a method of treating a patient having a tumor characterized by proliferation of neoplastic cells which comprises administering to the patient an amount of the compound effective to selectively induce terminal differentiation of such neoplastic cells, thereby inhibiting their proliferation and suppressing oncogenicity.
Type:
Grant
Filed:
April 17, 1995
Date of Patent:
March 4, 1997
Assignees:
Sloan-Kettering Institute for Cancer Research, The Trustees of Columbia Univeristy in the City of New York
Inventors:
Paul A. Marks, Richard A. Rifkind, Ronald Breslow, Branko Jursic
Abstract: The addition of DMSO to herbicidal compositions makes it possible to decrease the amount of active herbicidal agent required for desired activity without loss of effectiveness against target plants. The most preferred compositions for application to the plates contain 1-2.5% DMSO. However, in some instances, it may be advisable to use as much as 3% DMSO. The addition of the DMSO also results in increased stability to the composition.
Abstract: The invention relates to naphthalenesulfonic-pyrrolecarboxamido compounds of formula ##STR1## wherein n is zero or an integer of 1 to 3; R is a sulfonic acid residue; m is an integer of 1 to 3, or a pharmaceutically acceptable salt thereof, which are active as antiviral agents, in particular against Human Immunodeficiency Virus
Type:
Grant
Filed:
January 13, 1995
Date of Patent:
January 21, 1997
Assignee:
Farmitalia Carlo Erba S.r.L.
Inventors:
Nicola Mongelli, Giovanni Biasoli, Maria Grandi, Marina Ciomei, Maria C. Geroni
Abstract: An agent for preserving the freshness of plants containing 2"-O-glucosylisovitexin as an effective ingredient is disclosed. This agent is excellent in an effect of preserving the freshness of cut flowers and potted plants, and, moreover, is safe and has no problem of the pollution of the environment.
Type:
Grant
Filed:
May 30, 1995
Date of Patent:
December 31, 1996
Assignees:
Yoshihide Hagiwara, HIH Biocenter, Inc.
Abstract: A herbicidal composition comprising (i) N-phosphonomethylglycine or an agriculturally acceptable salt thereof in combination with (ii) paraquat or diquat or a mixture thereof and (iii) a herbicide which functions as a photosystem II inhibitor, for example diuron, chlortoluron, isoproturon, linuron, tebuthiuron, bentazone, oxadiazon, bromacil, ametryne, atrazine, cyanazine, hexazinone, metribuzin, simazine or terbuthylazine.
Abstract: There is provided a stable herbicidal composition comprising 1-{[o-(cyclopropylcarbonyl)-phenyl]sulfamoyl}-3-(4,6-dimethoxy-2-pyrimidin yl)urea in combination with one or more low-melting or liquid herbicides and alkaline white carbon.
Abstract: The present invention relates to a composition for enhancing synchrony of germination and emergence in plants and comprises an effective amount of a compound having the following general formula (I); ##STR1##
Type:
Grant
Filed:
March 31, 1993
Date of Patent:
May 21, 1996
Assignee:
National Research Council of Canada
Inventors:
Suzanne R. Abrams, Lawrence V. Gusta, Martin J. T. Reaney, Bruce E. Ewan
Abstract: Mixtures that use photoactive agents that inhibit the growth of algae are disclosed. The agents include concentrations of approximately at least 5% to approximately 50% TiO.sub.2, WO.sub.3, PtWO.sub.3 --Pt--WO.sub.3, or Pt--TiO.sub.2. The agents can be combined together, and/or each agent can be combined with various coatings such as but not limited to a cement or a polymer binder. The coatings and agents can be applyed to surfaces that are exposed to water such as but not limited to an aquarium, liners on the inner walls of swimming pools, drinking water tanks and the like. Further, applications can include using the novel surfacing agent as part of a solar water heater for both a home and a pool, wherein in the latter application the heater is connected between pool pumps and the pool so that when light is absorbed inside the heater, the surfacing agent becomes active for inhibiting the growth of algae. The photoactive agent can also be applied as a non-toxic algae-retardant marine paint.
Abstract: The present invention relates to a freshness retentive for cut flowers, which comprises a mixture of a silver compound and a primary amine and/or a nucleic acid-related substance and/or reaction products thereof. The silver compound is silver nitrate, silver acetate or silver phosphate; the primary amine is methylamine, ethylamine, monoethanolamine, tris(hydroxymethyl)aminomethane, 2-amino-2-methyl-1,3-propanediol, 2-amino-2-ethyl-1,3-propanediol, .alpha.-aminooxyacetic acid or aminoethoxyvinylglycine; and the nucleic acid-related substance is nucleic base, nucleoside, nucleotide, oligonucleotide, polynucleotide, purine derivative or pyrimidine derivative.The present freshness retentive for cut flowers demonstrates an extremely excellent effect on cut flowers highly sensitive to ethylene, e.g. carnation, Gypsophila elegans, sweet pea, etc., as well as on cut flowers low sensitive to ethylene, e.g. chrysanthemum, rose, orchid, etc., for their freshness retention.
Abstract: Disclosed are optically active secondary amine compounds and salts thereof having the general formula (I): ##STR1## a process for the preparation of the optically active secondary amine compounds and salts thereof, and the use of such compounds. Such compounds exhibit a high resolution power and hence are useful agents for optical resolution.
Abstract: Liquid herbicidal agents which contain a compound of the formula ##STR1## in the form of the racemate or of the L enantiomer, lower alkyl esters thereof or salts thereof with acids or bases (I) in combination with surfactants in the form ofa) alkyldimethyl-, fatty acid amidopropyldimethyl- or fatty acid amido ethyldimethylamine oxides orb) the betaine of coconut alkyldimethylaminoacetic acid or of coconut alkylaminopropionic acid orc) alkanesulfonates and mixtures thereof with fatty alcohol polyglycol ether sulfosuccinic acid monoesters or fatty alcohol polyglycol ether sulfates ord) alkylsulfosuccinic acid monoesters or fatty alcohol polyglycol ether sulfosuccinic acid monoesters and fatty alcohol polyglycol ether sulfosuccinic esters and their mixtures with fatty alcohol polyglycol ether sulfates ore) .alpha.
Type:
Grant
Filed:
December 1, 1992
Date of Patent:
February 13, 1996
Assignee:
Hoechst Aktiengesellschaft
Inventors:
Konrad Albrecht, Jean Kocur, Peter Langeluddeke
Abstract: The invention relates to herbicidal compositions which contain an effective amount ofA) one or more herbicides selected from the group comprising sulfonylureas and imidazolinones andB) one or more safeners selected from the group comprisingB1) phenyl-substituted imidazole-, imidazoline- and triazolecarboxylic acid derivatives and the benzyloxazolinecarboxylic acid derivatives and/orB2) quinolin-8-oxyalkanecarboxylic acid derivatives,with the exception of combinations of imidazolinones with compounds of the formula B2.The compositions are particularly suitable for protecting plants against phytotoxic secondary effects of sulfonylurea herbicides and imidazolinone herbicides. In the case of the imidazolinone herbicides, the invention also relates to a method of protecting corn plants, by applying post-emergence an effective amount of a quinolin-8-oxyalkanecarboxylic acid derivative together with the imidazolinone herbicide to the plants or the area under cultivation.
Abstract: Disclosed is an aromatic diamine compound represented by the formula (I) ##STR1## wherein R is H or CH.sub.3. Also disclosed is a bismaleimide compound represented by the formula (IV) ##STR2## wherein R is H or CH.sub.3, A resin forming composition comprising these compounds is also disclosed. The compounds are useful as raw materials for resins, and the resin forming composition and the resin can provide excellent heat resistance and impact resistance and low hygroscopicity.
Abstract: There are provided attracting and ingestion-stimulating agents for cockroach comprising as the active ingredient one or more compounds represented by the formula ##STR1## wherein R represents an amino group or an aminomethyl group. The attracting and ingestion-stimulating agents for cockroach exhibit a very potent attracting and ingestion-stimulating activity in the known species of house cockroach, both male and female.