Patents Examined by B. Burns
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Patent number: 5451702Abstract: A process for preparing substituted aromatic amines is provided which comprises contacting a nucleophilic compound and an azo containing compound in the presence of a suitable solvent system, reacting the nucleophilic compound and the azo containing compound in the presence of a suitable base and a controlled amount of protic material at a temperature of about 10.degree. C. to about 150.degree. C. in a confined reaction zone wherein the molar ratio of protic material to base is 0:1 to about 5:1 and reducing the product of the reaction of the nucleophilic compound and the azo containing compound under conditions which produce the substituted aromatic amine. In another embodiment, the substituted aromatic amines of the invention are reductively alkylated to produce alkylated diamines or substituted derivatives thereof.Type: GrantFiled: April 26, 1993Date of Patent: September 19, 1995Assignee: Monsanto CompanyInventors: Michael K. Stern, Brian K-M Cheng
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Patent number: 5430188Abstract: A process for the preparation of 2-alkyl-6-methyl-N(1'-methoxy-2'-propyl)-aniline by catalytic reductive alkylation wherein at least one mole equivalent of methoxyacetone is reacted with one mole equivalent of 2-alkyl-6-methyl-aniline in a liquid medium without an additional solvent, in the presence of a platinized carbon catalyst and hydrogen and in the presence of an acid cocatalyst under a hydrogen pressure of between 2.times.10.sup.5 and 1.times.10.sup.6 Pa at a temperature between 20.degree. and 80.degree. C., characterized in that the reaction mixture contains water from the beginning of the reaction and after the hydrogenation, base is added, the reaction mixture is filtered to separate the catalyst and the title compound recovered from the filtrate. The process is particularly useful for the preparation of N-substituted chloracetanilide herbicides.Type: GrantFiled: December 15, 1993Date of Patent: July 4, 1995Assignee: Ciba-Geigy CorporationInventors: Rolf Bader, Peter Flatt, Paul Radimerski
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Patent number: 5405878Abstract: Compositions for treating contact lenses, particularly rigid, gas permeable contact lenses, comprise a quaternary nitrogen-containing ethoxylated alkyl glucoside.Type: GrantFiled: June 18, 1993Date of Patent: April 11, 1995Assignee: Wilmington Partners L.P.Inventors: Edward J. Ellis, Jeanne Y. Ellis
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Patent number: 5399761Abstract: A method for the preparation of a 2-hydroxyarylaldoxime which comprises reacting hydroxylamine with a 2-hydroxyarylaldehyde, said reaction being performed in the presence of a compound of a metal of Group II, Group III, Group IVA or Group VIA of the Periodic Table and/or under such conditions that the 2-hydroxyarylaldehyde is at least partially in the form of a salt and/or complex of a metal of Group II, Group III, Group IVA or Group VIA of the Periodic Table.Type: GrantFiled: August 19, 1993Date of Patent: March 21, 1995Assignee: Zeneca LimitedInventor: Daniel Levin
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Patent number: 5399767Abstract: A process for producing 3,5-difluoroaniline, which comprises reacting a benzonitrile compound of the formula (I): ##STR1## wherein each of X.sub.1, X.sub.2 and X.sub.3 is hydrogen, chlorine, bromine or a cyano group, provided that at least one of X.sub.1 to X.sub.3 is a cyano group, with a mineral acid for hydrolysis and decarboxylation to obtain an aniline compound of the formula (II): ##STR2## wherein each of X.sub.4, X.sub.5 and X.sub.6 is hydrogen, chlorine or bromine, provided that at least one of X.sub.4 to X.sub.6 is hydrogen, and in the case of a compound of the formula (II) wherein X.sub.4, X.sub.5 and X.sub.6 are not simultaneously hydrogen, reacting such a compound with hydrogen in a presence of a catalyst for reduction to obtain 3,5 -difluoroaniline.Type: GrantFiled: February 8, 1994Date of Patent: March 21, 1995Assignee: Ishihara Sangyo Kaisha Ltd.Inventors: Rikuo Nasu, Motohiko Hamaguchi
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Patent number: 5399768Abstract: The present invention relates to a method of preparing 4,6-diaminoresorcinol from 1,2-dichloro-3,5-dinitrobenzene comprising the steps of:(a) contacting 1,2-dichloro-3,5-dinitrobenzene with a hydroperoxide in the presence of anhydrous base to form 2,3-dichloro-4,6-dinitrophenol;(b) contacting 2,3-dichloro-4,6-dinitrophenol with a hydroxy-containing compound to form 2-chloro-4,6-dinitroresorcinol; and(c) converting 2-chloro-4,6-dinitroresorcinol to 4,6-diaminoresorcinol, which is isolated as a salt or other stabilized form thereof,Type: GrantFiled: December 23, 1993Date of Patent: March 21, 1995Assignee: The Dow Chemical CompanyInventors: Zenon Lysenko, Richard G. Pews
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Patent number: 5393781Abstract: Method of controlling the zebra mussel by direct contact with peracetic acid or indirectly by application to an environment where control is desired. The biofouling of environments, such as fresh water intakes, conduits and storage systems of power and water treatment systems, and of processing streams of industrial plants, is thereby reduced or eliminated.Type: GrantFiled: July 8, 1993Date of Patent: February 28, 1995Assignees: FMC Corporation, The Research Foundation of the State University of New YorkInventors: Alexander M. Vegega, Claudio E. Manissero
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Patent number: 5371290Abstract: A process for the preparation of N,N-dialkylarylamines (I) by reacting arylamines (II) with alcohols (IIIa) or dialkyl ethers (IIIb) in the presence of an oxygen acid of phosphorus or in the presence of an ammonium salt thereof as catalyst, comprises reacting the oxygen acid of phosphorus with an arylamine (IV) before the reaction is commenced. The invention also relates to the regeneration of the catalyst by occasionally interrupting the reaction and treating the catalyst phase at from 100.degree. to 300.degree. C. with steam or water.Type: GrantFiled: January 31, 1994Date of Patent: December 6, 1994Assignee: BASF AktiengesellschaftInventors: Peter Reuter, Willi A. Weber, Hans Diem
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Patent number: 5360805Abstract: Compounds of the formula IV for use as local anaesthetica and analgetica, as well as a method for their preparation, their pharmaceutical preparations and their use.Type: GrantFiled: July 12, 1993Date of Patent: November 1, 1994Assignee: Aktiebolaget AstraInventors: Anna-Lena Ask, Rune V. Sandberg
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Patent number: 5348976Abstract: The present invention provides a condensed heterocyclic derivative represented by a formula: ##STR1## wherein R.sup.1 represents a lower alkyl group, an alkenyl group, or the like, R.sup.2, R.sup.3, R.sup.4, R.sup.5, and R.sup.6 independently represent a hydrogen atom, a lower alkyl, or the like, W is represented by --OC(O)--, --SC(O)--, or the like, and Z represents a 2-indolyl group or the like. The present invention also provides an agricultural or horticultural fungicide which comprises an amount of the condensed derivative known to be effective as a fungicide. The agricultural or horticultural fungicide according to the present invention exhibits a superior control effect for downy mildew and late blight, without harm to nonfungal, photosynthesizing plants.Type: GrantFiled: September 7, 1993Date of Patent: September 20, 1994Assignees: Kumai Chemical Industry Co., Ltd., Ihara Chemical Industry Co., Ltd.Inventors: Masaru Shibata, Shigekazu Ito, Jun-etsu Sakai, Shigeru Hayashi
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Patent number: 5292765Abstract: A method for reducing adverse effects of neurotoxic injury, which comprises administering to a patient susceptible to neurotoxic injury an effective amount, sufficient to reduce the injury, of a compound having an indolactam V ring system. Particularly preferred are compounds having ring stereochemistry as indicated in the following formula: ##STR1## The indicated substituents show preferred locations of substituents; preferred substituents are defined in the specification.Type: GrantFiled: November 27, 1991Date of Patent: March 8, 1994Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Dennis W. Choi, Dean M. Hartley
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Patent number: 5270287Abstract: N-Aryl tetrahydrophthalimides are useful as cotton defoliants nd desiccants.Type: GrantFiled: October 19, 1992Date of Patent: December 14, 1993Assignee: Valent U.S.A. CorporationInventor: Billy R. Corbin, Jr.
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Patent number: 5246968Abstract: A compound having glutamate receptor inhibitor activity represented by the formula: ##STR1## where R represents a hydrogen atom or a group of the formula: ##STR2## m and n each represents an integer of 3 or 4 and p represents an integer of 0 or 1, or a salt thereof is provided. The compounds are useful for an insecticide.Type: GrantFiled: June 30, 1992Date of Patent: September 21, 1993Assignees: Takeda Chimical Industries, Ltd., Tokyo Metropolitan Institute for NeurosciencesInventors: Terumi Nakajima, Yoshio Aramaki, Tadashi Yasuhara, Tsutomu Higashijima, Nobufumi Kawai, Akiko Miwa, Masanori Yoshioka
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Patent number: 5202488Abstract: A method of dehydrogenating 3-amino-2-cyclohexene-1-one with a supported palladium or palladium-platinum catalyst in a solvent in the presence of base to produce 3-aminophenol and its use directly without purification to produce 3,4'-oxydianiline.Type: GrantFiled: April 15, 1991Date of Patent: April 13, 1993Assignee: E. I. du Pont de Nemours and CompanyInventor: Stephen E. Jacobson
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Patent number: 5173105Abstract: An herbicide compound of the formula ##STR1## wherein R is halogen, C.sub.1 -C.sub.2 alkyl, C.sub.1 -C.sub.2 alkoxy, nitro; cyano; C.sub.1 -C.sub.2 haloalkyl, or R.sup.a SO.sub.n -- wherein n is 0 or 2 and R.sup.a is C.sub.1 -C.sub.2 alkyl;R.sup.1 is hydrogen or C.sub.1 -C.sub.4 alkyl;R.sup.2 is hydrogen or C.sub.1 -C.sub.4 alkyl; orR.sup.1 and R.sup.2 together are alkylene having 2 to 5 carbon atoms;R.sup.3 is hydrogen or C.sub.1 -C.sub.4 alkyl;R.sup.4 is hydrogen or C.sub.1 -C.sub.4 alkyl; orR.sup.3 and R.sup.4 together are oxo;R.sup.5 is hydrogen or C.sub.1 -C.sub.4 alkyl;R.sup.6 is hydrogen or C.sub.1 -C.sub.4 alkyl; orR.sup.5 and R.sup.6 together are alkylene having 2 to 5 carbon atoms;R.sup.7 and R.sup.8 independently are (1) hydrogen; (2) halogen; (3) C.sub.1 -C.sub.4 alkyl; (4) C.sub.1 -C.sub.4 alkoxy; (5) trifluoromethoxy; (6) cyano; (7) nitro; (8) C.sub.1 -C.sub.4 haloalkyl; (9) R.sup.b SO.sub.n -- wherein n is the integer 0, 1 or 2; and R.sup.b is (a) C.sub.1 -C.sub.4 alkyl; (b) C.sub.1 -C.sub.Type: GrantFiled: February 5, 1991Date of Patent: December 22, 1992Assignee: Imperial Chemical Industries PlcInventor: Christopher G. Knudsen
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Patent number: 5145977Abstract: There is disclosed a herbicide composition in which a postemergent herbicide is activated by the inclusion of a silicone glycol adjuvant consisting essentially of (i) a silicone glycol having an average structure ##STR1## wherein Me denotes a methyl radical, and (ii) a silicone glycol dispersant compound for component (i). When compared to similar prior art silicone glycol adjuvants not having an acetoxy terminated glycol chain, the compositions of the present invention provide enhanced rainfastness in the control of weeds, particularly velvetleaf plants.Type: GrantFiled: February 26, 1990Date of Patent: September 8, 1992Assignee: Dow Corning CorporationInventors: Lenin J. Petroff, David J. Romenesko, Bradley C. Bahr
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Patent number: 5126659Abstract: A method for establishing a test mode in an electronic module (10) having an internal fault detector (26) that limits the current in an output transistor (Q1) when an abnormal signal level appears at an output pin (16). An abnormal signal level is intentionally established on the output pin to enable the fault detector, and such enablement is sensed to trigger the test mode within the module. Apparatus for implementing this method in a voltage regulator is also disclosed.Type: GrantFiled: July 13, 1990Date of Patent: June 30, 1992Assignee: Motorola, Inc.Inventor: Arthur J. Edwards
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Patent number: 5103169Abstract: Field Effect Transistors are used to replace mechanical relays and to minimize the distance a Device Under Test (DUT) must drive a signal path to the receiver, to minimize insertion losses in critical paths to the DUT, and generally increase reliability in integrated test systems by eliminating the need for relays to test integrated circuits.Type: GrantFiled: November 15, 1989Date of Patent: April 7, 1992Assignee: Texas Instruments IncorporatedInventors: Dale A. Heaton, James E. Bartling
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Patent number: 5077314Abstract: A method is disclosed for the containment and controlled release of and the substantial reduction of the leaching from the site of application of agricultural chemicals. In the disclosed method, the agricultural chemicals are applied to the soil dispersed in an aqueous gel-forming composition. Novel compositions of the agricultural chemicals dispersed in aqueous gel-forming compositions are also disclosed.Type: GrantFiled: May 25, 1990Date of Patent: December 31, 1991Assignee: Pfizer Inc.Inventors: Judson C. Philips, Hazen L. Hoyt, IV, Christopher A. Macri, Wesley L. Miller, John J. O'Neill
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Patent number: 5059240Abstract: 2,3-substituted 1,8-naphthyridines of the general formula I ##STR1## where: R is hydrogen or C.sub.1 -C.sub.4 -alkyl (n=1 or 2)R.sup.1 is amino or substituted amino,XR.sup.5, where X is oxygen or sulfur and R.sup.5 is hydrogen, C.sub.1 -C.sub.12 -alkyl, C.sub.1 -C.sub.4 -alkoxycarbonyl-((C.sub.1 -C.sub.4)-alkyl, C.sub.5 -C.sub.8 -cycloakyl, substituted or unsubstituted phenyl, substituted or unsubstituted phenyl-(C.sub.1 -C.sub.3)-alkyl,halogen,isothiorhonium halide,C.sub.1 -C.sub.12 -alkyl,C.sub.1 -C.sub.4 -alkoxycarbonyl-C.sub.1 -C.sub.4 -alkyl,substituted or unsubstituted phenyl or phenyl-(C.sub.1 -C.sub.3)-alkyl,R.sup.2 is C.sub.1 -C.sub.4 -alkyl, cyano, carboxyl or a group ##STR2## where X is oxygen or sulfur,B is C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.6 -alkoxy or alkylthio, amino, mono- or dialkylamino, where each alkyl radical is of 1 to 4 carbon atoms, morpholino, piperidyl, chlorine, bromine or substituted or unsubstituted phenyl,D is C.sub.1 -C.sub.4 alkyl or NH.sub.2 andR.sup.6 is hydrogen, C.Type: GrantFiled: March 1, 1990Date of Patent: October 22, 1991Assignee: BASF AktiengesellschaftInventors: Helmut Hagen, Juergen Pfister, Hans Ziegler, Bruno Wuerzer, Karl-Otto Westphalen