Abstract: This invention relates to herbicidally active substituted benzisoxazole (or benzisothiazole) compounds and to the use of such compounds to control the growth of noxious plants, i.e., weeds.
Abstract: Dioxolobenzisoxazole derivatives of the formula ##STR1## wherein R.sub.1 is a phenyl group which may be substituted with a halogen atom, a lower alkyl group having 1-3 carbon atoms or a lower haloalkyl group, or a thienyl group; R.sub.2 is a hydrogen atom or a lower alkyl group having 1-4 carbon atoms; and X and Y which may be the same or different represent a hydrogen atom or a halogen atom, as well as non-toxic salts thereof wherein R.sub.2 is a hydrogen atom, a process for preparing the same and a pharmaceutical composition containing the same are disclosed.The derivatives have diuretic and uricosuric activities and, therefore, are useful as a drug for treating hyperuricemia or hypertension.
Type:
Grant
Filed:
March 18, 1986
Date of Patent:
March 22, 1988
Assignee:
Chugai Seiyaki Kabushiki Kaisha
Inventors:
Hiroshi Koga, Takashi Dan, Haruhiko Sato, Etsuro Onuma
Abstract: Compounds useful as antiviral agents are depicted in the formula: ##STR1## wherein: X is oxygen or NH, Y is hydrogen, iodo, fluoro, methyl or trifluoromethyl, Z is hydrogen or fluoro and Z' is fluoro; and the wavy line indicates that the group may be above or below the plane of the ring; and the pharmaceutically acceptable acid addition salts thereof.
Type:
Grant
Filed:
April 14, 1986
Date of Patent:
November 3, 1987
Assignee:
Syntex (U.S.A.) Inc.
Inventors:
Julien P. H. Verheyden, John C. Martin, G. V. Bindu Madhavan, Daniel P. C. McGee, Ernest J. Prisbe
Abstract: A class of new cephem compounds is now provided, which is useful as antibacterial agent and is represented by the general formula (I) ##STR1## wherein R.sup.1 is methyl group or carboxymethyl group and R.sup.2 is carboxyl group or a protected carboxyl group, and a pharmaceutically acceptable salt or ester thereof.