Abstract: The present invention relates to benzoxazinones of formula I: ##STR1## or stereoisomeric forms or mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, methods of using the same for treating viral infection or as an assay standard or reagent, and intermediates and processes for making the same.
Type:
Grant
Filed:
October 21, 1998
Date of Patent:
October 31, 2000
Assignee:
DuPont Pharmaceutical Company
Inventors:
Joseph Marian Fortunak, Rodney Lawrence Parsons, Jr.
Abstract: Pyrrolopyrimidines of formula (I) in which R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and A have the meanings given in the description, and their acid-addition salts and metal salt complexes are very highly suitable for combatting vegetable and animal pests.Novel pyrrolopyrimidines of formula (Ia) in which R.sup.6, R.sup.7, R.sup.8, R.sup.9, R.sup.10 and Z have the meanings given in the description, and their acid-addition salts and metal salt complexes, and a process for their production.
Type:
Grant
Filed:
December 11, 1998
Date of Patent:
August 15, 2000
Assignee:
Bayer Aktiengesellschaft
Inventors:
Dietmar Kuhnt, Klaus-Gunther Tietjen, Hermann Uhr, Robert Markert, Ralf Tiemann, Klaus Stenzel, Stefan Dutzmann, Christoph Erdelen, Ulrike Wachendorff-Neumann