Abstract: Intravascular devices and systems include a flexible elongate member having a component configured to detect a physiological condition of a patient when the flexible elongate member is in a vasculature of the patient. The probe may also include a connector junction non-rotatably and permanently secured to the proximal portion of the flexible elongate member. The connector junction may be sized for grasping by a health care provider and for rotation to rotate the flexible elongate member when the flexible elongate member is in a vasculature of the patient. The connector junction may include a slack chamber to accommodate slack in a conductor that may be utilized when the flexible elongate member is introduced through tortious vasculature.

Abstract: A method for attenuation correcting a PET image of a target includes locating a radiopaque structure by MRI scan of the target; fitting a model of the radiopaque structure to the MRI scan image; and correcting attenuation of the PET image based on the fitted model.

Abstract: An embryo transfer catheter or other medical device has a shaft extruded with two layers. The outer layer is relatively thick and contains gas bubbles sufficient to increase the visibility of the catheter under ultrasound observation but with a density that allows material within the catheter to be viewed by the eye. The inner layer is relatively thin and is free of bubbles so that it provides a smooth bore to the catheter.

Abstract: A non-invasive variable depth ultrasound treatment method and system comprises a variable depth transducer system configured for providing ultrasound treatment to a patient. An exemplary variable depth transducer system can comprise a transducer configured to provide treatment to more than one region of interest, such as between a deep treatment region of interest and a superficial region of interest, and/or a subcutaneous region of interest. The variable depth transducer can comprise a transduction element having a piezoelectrically active layer, matching layers and/or other materials for generating radiation or acoustical energy. The variable depth transducer may be configured to operate at moderate frequencies within the range from approximately 750 kHz to 20 MHz or more. In addition, the transduction element may be configured with a variable depth device comprising one or more materials configured to allow for control and focusing/defocusing of the acoustic energy to more than one region of interest.

Abstract: The fluorescent light phantom device 1 is provided with: a phantom support 10 having fluorescent light phantom containers 1b, 1c, 1d and 1e; and fluorescent light phantoms 12, 13, 14 and 15 which are constituted of a medium that reproduces at least one of light scattering and light absorption of an object to be measured and a fluorescent coloring matter contained in the medium of a predetermined concentration and are stored in the fluorescent light phantom containers 1b, 1c, 1d and 1e.

Abstract: Computerized information acquisition and processing apparatus. In one embodiment, the apparatus includes an ingestible (e.g., swallowable) computerized device that includes a video apparatus, digital processor apparatus, and a wireless interface. A non-ingestible portion of the system communicates with the ingestible device via the wireless interface and, using computer software and algorithms, processes video data generated by the ingestible device relating to the intestinal tract of a living subject, so as to enhance the speed and/or accuracy of review by a physician or other individual. In one variant, the algorithmic processing by the non-ingestible apparatus includes one or more of: (i) color intensity analysis; (ii) artifact shape analysis; and/or (iii) inter-frame similarity analysis. In another variant, the ingestible device is configured to compress the data using the processor apparatus prior to transmission over the interface to conserve wireless bandwidth.

Abstract: Disclosed herein are a medical imaging apparatus and a method of providing medical images which may more accurately quantify elasticity of tissues. The medical imaging apparatus includes a display unit displaying an elastic image in which different colors are mapped according to strain values of tissues within an object, and a controller, when a target area containing lesion tissues and a reference area containing normal tissues are set in the elastic image, calculating a representative target area value representing strain values of the target area and a representative reference area value representing strain values of the reference area, and displaying a color reference area, expressing distribution of the representative reference area value in the reference area in color, through the display unit.

Abstract: A system and method for automatic registration of medical images includes accessing image data of a subject and plurality of elongated fiducial markers arranged in an asymmetrical orientation and analyzing the image data to detect the elongated fiducial markers by applying a line filter to treat the elongated fiducial markers as lines within the image data. The system and method also includes matching the elongated fiducial markers within the image data to a model of the elongated fiducial markers, registering the image data with a coordinate system based on the matching, and generating a report indicating at least the registered image data.

Abstract: A minimally invasive applicator device for treatment of intervertebral tissue containing at least one target nerve includes an insertion device having a proximal end and a distal end for insertion into the intervertebral tissue containing at least one target nerve, an ultrasound transducer device coupled to the distal end of the insertion device, and an external RF power generator electrically that provides power to the ultrasound transducer device. The ultrasound transducer device includes an array of a plurality of transducer crystals which are all aligned along a line defined by an axis enclosed by each of the plurality of transducer crystals disposed sequentially and longitudinally adjacent each other along the axis to form a customized flexible array along the applicator device. Ultrasound radiative output treatment outward from the axis of the transducer crystals allows for treatment of the intervertebral tissue containing at least one target nerve.

Abstract: A system includes a parameter generation system to determine at least one parameter for an injection procedure (for example, a parameter of an injection protocol or an imaging system parameter), the parameter generator system includes a physiologically based pharmacokinetic model to model propagation of a contrast medium injected into a patient including at least one of a non-linear saturation term in a peripheral venous compartment, at least one configurable transport delay term through at least one compartment, or an adaptation to model volumetric flow rate of blood and an effect thereof on the propagation of contrast medium after injection of contrast medium ceases. The physiologically based pharmacokinetic model can, for example, be discretizable.

Abstract: Disclosed are a radio frequency (RF) coil assembly and a magnetic resonance imaging (MRI) apparatus using the RF coil assembly. The RF coil assembly includes a plurality of coils, and a plurality of distributed connecting elements to connect a first coil and a second coil of the coils. Each of the connecting elements is set to one of a short state and an open state. Isolation between the first coil and the second coil may vary depending upon the state of each of the connecting elements.

Abstract: The present invention provides improved medical devices equipped with a visualization device for intubation, ventilation, drug delivery, feeding and continuous remote monitoring of a patient. The present invention also provides methods for rapid and accurate placement of a medical device in a patient and continuous real time monitoring, including a remote monitoring, of the patient after the placement.

Abstract: Described are methods, systems, and apparatus, including computer program products for examining a blood vessel wall. The blood vessel wall is illuminated with near-infrared light. Reflected near-infrared light from the blood vessel wall is received. A reflectance spectrum based on the reflected near-infrared light from the blood vessel wall is determined. Whether the reflectance spectrum is indicative of a presence of a lipid core plaque (LCP) by applying an LCP classifier to the reflectance spectrum is determined. A thickness of an LCP cap is determined by applying an LCP cap thickness classifier to the reflectance spectrum if the reflectance spectrum is indicative of the presence of the LCP. Indicia of the thickness of the LCP cap are displayed.

Abstract: An implantable magnetic relaxation sensor is provided that comprises superparamagnetic nanoparticies functionalized with one or more agents that bond with a biomarker of interest. The sensor is configured for minimally-invasive implantation into a human or animal, and is configured to indicate the implanted sensor's cumulative exposure to the biomarker of interest by analysis using magnetic resonance relaxometry.

Abstract: An ultrasound probe connected to various diagnostic apparatuses and a method of operating the ultrasound probe. The includes transmitting an ultrasound signal to an object and receiving a response signal reflected from the object; acquiring information regarding a diagnostic apparatus connected to the ultrasound probe; determining a type of data that may be processed by the diagnostic apparatus based on the information regarding the diagnostic apparatus; generating transmission data corresponding to the determined type of data from the response signal; and transmitting the transmission data to the diagnostic apparatus.

Abstract: Systems and methods are provided for determining a right ventricular transit time for a patient. An echodense contrast is injected into a patient. A first representative region, representing the right ventricle of the patient, is selected. A second representative region, representing the bifurcation of the main pulmonary artery, is selected. Respective first and second time series of intensity values for the first and second representative regions are generated via echocardiography. The right ventricular transit time is determined from the first and second time series of intensity values. The right ventricular transit time is displayed to a user.

Abstract: An ultrasonographic system includes an electronic memory to store a table that relates subject information to a plurality of frequencies, and a frequency setting unit that sets the examination frequency to one of the frequencies stored in the table. The frequency setting unit sets the examination frequency based on selection of subject information from the table, and the examination frequency is used to perform ultrasound examination on the subject according to the selected information.

Abstract: A surgical imaging device and method configured to be inserted into a surgical site. The surgical imaging device includes a plurality of prongs. Each one of the prongs has an image sensor mounted thereon. The image sensors provide different image data corresponding to the surgical site, thus enabling a surgeon to view a surgical site from several different angles. The prongs may be moveable between a first position, suitable for insertion through a small surgical incision, and a second position, in which the prongs are separated from each other. In addition, the prongs may be bendable.

Abstract: Disclosed is an ultrasonic diagnostic apparatus including a main body, at least one input/output unit coupled to one side of the main body to input data to the main body or to output data transmitted from the main body, and a connection unit to connect the input/output unit and the main body to each other. The connection unit includes plural first connection members, each of which is connected at one end thereof to the main body and at the other end thereof to at least a portion of the input/output unit and has a variable length to move the input/output unit relative to the main body, and at least one second connection member coupled to the first connection members and at least one of the main body or the input/output unit so as to come into contact with the same at a point to support load of the input/output unit.

Abstract: A system and method for detecting a tissue property. The system comprises a first unit positioned outside a patient body and a second unit positioned inside the patient's body. The first unit includes a first housing, and a magnetic field source supported by the first housing. The second unit includes a second housing, a pressure sensor supported by the second housing, a localization module supported by the second housing, a controller, and a power source. The pressure sensor is configured to detect an indentation force applied to the tissue, and the second unit is configured to wirelessly transmit the indentation force data and localization data to a computer to generate a volumetric stiffness map for the tissue.