Abstract: An attenuated feline recombinant herpesvirus 1 (FHV-1), which is prepared by identifying gene regions in the genome wherein inserted foreign genes can be expressed without affecting the replication of FHV-1 and has least two types of foreign nucleic acid sequences inserted thereinto, usable as a vector virus or a vaccine. In this attenuated recombinant FHV-1, at least two types of foreign genes are inserted in such a manner as allowing the expression into two different gene regions exerting no lethal effect on the proliferation of the virus in the feline herpesvirus 1 genome.
Type:
Grant
Filed:
October 5, 2001
Date of Patent:
November 20, 2007
Assignee:
Kyoritsu Seiyaku Corporation
Inventors:
Kazuo Kawakami, Masahiko Kishi, Masami Mochizuki