Abstract: The present invention relates to a composition comprising particles of a polymer that is surface-stabilized with a stabilizer, the polymer of the particles being a C1-C4 alkyl (meth)acrylate polymer; the stabilizer being an isobornyl (meth)acrylate polymer chosen from isobornyl (meth)acrylate homopolymer and statistical copolymers of isobornyl (meth)acrylate and of C1-C4 alkyl (meth)acrylate present in an isobornyl (meth)acrylate/C1-C4 alkyl (meth)acrylate weight ratio of greater than 4, at least one hydrocarbon-based oil and at least one mineral thickener chosen from optionally modified clays and optionally modified silicas, or mixtures thereof. The invention also relates to a process for making up and/or caring for keratin materials, in which said composition is applied.
Type:
Grant
Filed:
December 17, 2015
Date of Patent:
April 14, 2020
Assignee:
L'OREAL
Inventors:
Roshanak Debeaud, Hong Li, Stephane Douezan, Sylvie Manet, Veronique Ferrari
Abstract: The present invention relates to hair care compositions comprising malodor reduction compositions and methods of using such hair care compositions. Such hair care compositions comprising the malodor control technologies disclosed herein provide malodor control without leaving an undesirable scent and when perfume is used to scent such compositions, such scent is not unduly altered by the malodor control technology.
Type:
Grant
Filed:
March 23, 2017
Date of Patent:
April 7, 2020
Assignee:
The Procter and Gamble Company
Inventors:
Stacy Renee Hertenstein, Judith Ann Hollingshead, Jennifer Anne Corder, James Anthony Staudigel
Abstract: A granulation formulation of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide or pharmaceutically acceptable salt thereof, which is adapted for reconstitution with an aqueous vehicle, and associated oral suspension.
Type:
Grant
Filed:
August 22, 2018
Date of Patent:
March 24, 2020
Assignee:
Novartis AG
Inventors:
Gossett Augustus Campbell, Helen Richardson, Peter A. Williams
Abstract: The present invention provides a coprocessed excipient composition and a method of producing the same. The coprocessed excipient comprises vinyl lactam derived polymer and a deagglomerated coprocessing agent. The coprocessing agent is fumed silica, colloidal silica or silicon dioxide. The coprocessed excipient is prepared by a continuous process and has a Brookfield cohesion of less than 0.12 kPa, a bulk density of at least 0.249 gram/milliliter and a flow property as measured by Johanson flow rate number increase from 1.1 to 5.0 fold.
Type:
Grant
Filed:
March 12, 2014
Date of Patent:
March 24, 2020
Inventors:
Divya Tewari, Yevgeniya A. Titova, Brad Beissner, Thomas Durig
Abstract: The invention thus relates to the cosmetic use of a siliceous material that may be obtained by hydrolysis and condensation, in the presence of water, of at least one tetraalkoxysilane of formula (I) below: Si(OR2)4 (I) and of an alkyltrialkoxysilane of formula (II) below: R1Si(OR2)3 (H) in which: R1 denotes a C7 to C20 alkyl group, optionally interrupted in its chain with an O or S atom or with an NH group or a carbonyl group (CO), R2 denotes a C1-C4 alkyl group. Preferentially, the siliceous material is present in a composition comprising a cosmetically acceptable medium. The invention also relates to a cosmetic process for treating human body odour, in particular underarm odour and optionally human perspiration, which consists in applying to human keratin materials the said siliceous material or a composition containing the same in a cosmetically acceptable medium.
Abstract: The present invention is directed to a process for producing inorganic particulate material, the material obtainable by such process, a modified release delivery system comprising the material and the use of the material for the administration of a bioactive agent.
Type:
Grant
Filed:
November 8, 2016
Date of Patent:
March 3, 2020
Assignee:
Merck Patent GmbH
Inventors:
Mario Maio, Eugenia Breininger, Karin Cabrera Perez, Ulrich Lang, Benjamin Peters, Thomas Puchert, Christoph Saal, Michael Schulz
Abstract: Disclosed is a fiber elasticity conserving hair relaxer composition having an alkalinity of at least pH 12 comprising a fiber elasticity conserving amount of at least one hair fiber elasticity conserving agent selected from the group consisting of poly-organosiloxanes containing, per molecule, at least one siloxyl unit substituted with at least one group having one or more of a sterically hindered piperidinyl functional group. The composition substantially ameliorates the loss of hair fiber elasticity that frequently occurs during the hair relaxing step of a process for relaxing the natural curl of hair under such strongly alkaline conditions.
Abstract: The performance of a mammal, manifested as a reduced oxygen uptake (VO2) during physical exercise, can be enhanced by administering to said mammal a non-toxic amount of nitrate and/or nitrite. Liquid, semi-solid and solid snack and food products and nutritional supplements, such as sport drinks are made available.
Abstract: As disclosed herein, novel compositions including steroid hormones, such as trimegestone (TMG) and progesterone (P4), provide treatments for term and preterm labor with significant effects on the delay of delivery. Delay and block of delivery occurs when both P4 and TMG are administered late in gestation in pregnant rat and guinea pig animal models. TMG exhibits remarkable drug efficacy, achieving the same inhibition as P4, but at much lower doses. These hereto unknown effects of TMG on the processes of cervical ripening and uterine contraction provide a novel approach for extending pregnancy term, including reducing a likelihood of preterm and/or term labor, along with improved methods of administration. Other diseases and/or conditions may be treated with TMG, such as dysmenorrhea or luteal insufficiency for sustaining pregnancy.
Type:
Grant
Filed:
September 15, 2017
Date of Patent:
February 11, 2020
Assignee:
Dignity Health
Inventors:
Robert E. Garfield, Shao-Qing Shi, Leili Shi
Abstract: A composition is provided, including an emulsion of an aqueous phase in a lipophilic phase, wherein the composition includes water, more than 8 wt % butylene glycol, one or more nonionic polysaccharides, and one or more lipophilic materials. The composition may be prepared by a method including the steps of a) mixing the one or more lipophilic materials with an aqueous mixture including water, the one or more nonionic polysaccharides, and the butylene glycol at a temperature in a range from 30 to 70° C. until homogeneity is reached; b) cooling the product of step a) to room temperature; and optionally c) adding ethanol and/or aluminum starch octenylsuccinate to the product of step b) with mixing. A method of caring for a keratin material in an animal includes applying an effective amount of the composition to the keratin material.
Abstract: The present invention relates to a method of manufacturing an orally disintegrating dosage form which masks a bitter or unpleasant taste. A composition including a ratio of excipients and a coated active substance prevents a coating layer on the active substance from being destroyed during manufacture.
Type:
Grant
Filed:
July 20, 2015
Date of Patent:
February 4, 2020
Assignee:
CHOONGWAE PHARMA CORPORATION
Inventors:
Mikyoung Hahn, Jin-Woo Choi, Dae-Hyeon Kim
Abstract: A new modus and a new regimen of administration of divalent iron relates to therapy of hyposideremia, at the same time reducing toxic side effects. New formulations containing divalent iron compounds are adapted to release iron for intrabuccal absorption, preferably by sublingual absorption, that achieve these objects.
Abstract: A hair color which achieves excellent texture consistently from during plain rinsing in the treatment with the hair color to the dry state after the treatment is provided includes a hair cosmetic composition containing (A) one or more cationic polymers, (B) one or more cationic surfactants with a counter ion which is chlorine or an alkyl sulfate, (C) one or more selected from hydrocarbon oils, ester oils, waxes and vegetable oils, (D) one or more nonionic surfactants and (E) one or more selected from oleyl alcohol and oleic acid.
Abstract: A crosslinked polyorganosiloxane is obtained from the free radical-initiated addition polymerization of polymerizable polyorganosiloxane containing at least two free radical polymerizable groups.
Type:
Grant
Filed:
June 7, 2016
Date of Patent:
December 24, 2019
Assignee:
Momentive Performance Materials Inc.
Inventors:
Zhimin Xing, Yun Huang, Sigfredo Gonzalez, Benjamin Falk, Anne Dussaud
Abstract: The present invention relates to a composition, preferably a cosmetic composition, in particular for coating keratin fibres such as the eyelashes, comprising: —an aqueous phase, —a lamellar phase L? formed by an aqueous phase-structuring surfactant system, said surfactant system comprising a content of surfactant(s) of greater than or equal to 15% by weight relative to the total weight of the composition, —at least one (poly)oxyalkylenated hydrophilic polymer present in a content of greater than or equal to 3% by weight of solids relative to the total weight of the composition, the hydrophilic polymer(s) having a weight-average molecular mass Mw ranging from 1500 to 500 000 g/mol. The present invention also relates to a process for coating keratin fibres.
Abstract: An antiseptic composition suitable for use on skin and wounds comprising a source of an antimicrobial agent and an agent which disrupts biofilms. More, particularly the invention relates to a composition capable of providing effective antimicrobial activity while at the same time avoiding wound and skin irritation and retardation of wound healing.
Type:
Grant
Filed:
December 7, 2016
Date of Patent:
December 3, 2019
Assignee:
ConvaTec Technologies Inc.
Inventors:
Steven L. Percival, Phillip G. Bowler, David Parsons
Abstract: There is provided the use of compounds of formula I wherein R1, R2, R3 and X have meanings given in the description, for the preparation of a medicament for killing clinically latent microorganisms. There is also provided the use of compounds of formula I for treating microbial infections, as well as certain compounds of formula I per se.
Type:
Grant
Filed:
May 30, 2017
Date of Patent:
December 3, 2019
Assignee:
HELPERBY THERAPEUTICS LIMITED
Inventors:
Petra Helga Beck, Marc Barry Brown, David Edward Clark, Anthony Coates, Hazel Joan Dyke, Yanmin Hu, Derek John Londesbrough, Keith Mills, Thomas David Pallin, Gary Patrick Reid, Gerlinda Stoddart
Abstract: The present invention relates to mesoporous silica coated nanoparticles comprising a metal oxide nanoparticle core; and a mesoporous silica shell encapsulating metal oxide core; wherein said mesoporous silica shell and the metal oxide core are not in full contact. The nanoparticles of the invention are useful as diagnostic and therapeutic agents.
Type:
Grant
Filed:
July 28, 2015
Date of Patent:
December 3, 2019
Assignee:
Regents of the University of Minnesota
Inventors:
Christy L. Haynes, Katherine Rose Hurley, Samuel Michael Egger
Abstract: Described herein are oral abuse deterrent pharmaceutical compositions, methods for making the same, and methods for treating pain by administering the pharmaceutical composition to a subject in need thereof. In particular, an oral abuse deterrent pharmaceutical composition comprising a soft capsule and a controlled release matrix comprising oxycodone are described.
Type:
Grant
Filed:
October 27, 2017
Date of Patent:
November 19, 2019
Assignee:
Patheon Softgels, Inc.
Inventors:
Justin Hughey, Saujanya Gosangari, Chue Hue Yang
Abstract: The present invention relates to a hair styling composition with high amount of waxes and fatty compounds, use, and kit-of-parts thereof. It has been found out that a composition comprising one or more fatty substances, one or more wax components, one or more specific anionic surfactants and one or more styling polymers provides satisfactory styling effect on coarse hair and has satisfactory storage stability.