Abstract: Provided is a digital stethoscope capable of outputting a heart sound data and/or a therapeutic data. The digital stethoscope includes a housing, a physiological data acquisition unit configured to acquire the heart sound data, a therapeutic data unit providing the therapeutic data and an output unit configured to output heart sound data and/or therapeutic data, wherein the physiological data acquisition unit and the therapeutic data unit are provided within the housing.

Abstract: Respiratory function can be preserved and/or enhanced in patients with a respiratory insufficiency using a photoceutical applied by a photoceutical medical device to at least one primary inspiratory muscle and/or a lung. At least one site on a body of a patient can be selected for delivery of the photoceutical to the muscle(s); and the photoceutical can be applied at the at least one site by the photoceutical medical device for a time period from a first start time to a first end time to treat the at least one primary inspiratory muscle and/or the lung of the patient to preserve and/or enhance the respiratory function. The photoceutical can include a light signal with at least one delivery scheme (e.g., superpulsed, pulsed. and/or continuous) and one or more wavelengths.

Abstract: Disclosed in an accessory circuit for a modular energy system. The accessory circuit includes an accessory port configured to receive an accessory, a power supply, a processor, an isolation barrier configured to electrically isolate the processor and the power supply from the accessory port. A flexible serial communication interface is coupled between the processor and the accessory port. The flexible serial communication interface is configured to support multiple communication protocols. A presence detection circuit is coupled between the accessory port and the processor. The presence detection circuit is configured to detect presence of an accessory connected to the accessory port.

Abstract: An atrial flutter identification method includes placing a catheter comprising multiple electrodes in a coronary sinus (CS) of a heart of a patient, so that some of the electrodes overlap a left atrium (LA) of the heart and some of the electrodes overlap a right atrium (RA) of the heart. Intra cardiac (IC) electrophysiological (EP) signals are acquired with the electrodes. Respective signal-stability measures are estimated over the signals acquired by the electrodes overlapping the LA and over the signals acquired by the electrodes overlapping the RA. When one of the signal-stability measures is above a first threshold while the other of the signal-stability measures is below a second threshold, an atrium is indicated, that corresponds to a highest among the signal-stability measures as a source of atrial flutter.

Abstract: In various embodiments electrical stimulators are provided for transcutaneous and/or epidural stimulation. In certain embodiments the stimulator provides one or more channels configured to provide one or more of the following stimulation patterns: i) monophasic electrical stimulation with a DC offset; ii) monophasic electrical stimulation with charge balance; iii) delayed biphasic electrical stimulation with a DC offset; iv) delayed biphasic electrical stimulation with charge balance; v) amplitude modulated dynamic stimulation; and/or vi) frequency modulated dynamic stimulation.

Abstract: This disclosure is directed to devices, systems, and techniques for delivering electrical stimulation. In some examples, a system includes processing circuitry configured to: receive information representative of a bioelectric brain signal recorded from a brain of a patient; and determine, based on the information, at least one pathological frequency of the bioelectric brain signal. Additionally, the processing circuitry is configured to select, based on the at least one pathological frequency, a sequence of pulse bursts at a pulse burst frequency, the sequence of pulse bursts at least partially defining electrical stimulation deliverable to an area of a brain of a patient, wherein adjacent pulse bursts within the sequence comprise different intra-burst pulse frequencies; and control a medical device to deliver the electrical stimulation comprising the sequence of pulse bursts to the area of the brain of the patient.

Abstract: Embodiments described herein relate to systems, devices, and methods for monitoring brain activity and delivering electrical brain stimulation to a patient. In some embodiments, a system can deliver responsive electrical stimulation in a closed-loop manner and can offer real-time or near real-time monitoring of induced neurophysiological effects. After detecting a targeted brain pattern (i.e., an epileptic seizure), the system may deliver high-intensity ultra-short electrical stimulation impulses non-invasively or minimal-invasively to diminish or stop the neural oscillations underlying the epileptic seizure. The stimuli are delivered in time and space, relative to the emerging seizure rhythm patterns, such that they diminish or terminate the seizure. The system may include an implantable device including one or more electrodes electrically coupled to one or more processors.

Abstract: A device for surgery that accommodates multiple different implements. The implements may be exchanged or changed out for one another over the course of a surgery in a manner that does not require disengagement of the device from a surgical site. As a result, the need to re-insert the device into the patient and other hazards associated with multiple trips into the surgical site may be minimized. In one embodiment, the device includes cannula architecture to avoid use of a separate cannula at the surgical site.

Abstract: A leadless biostimulator, such as a leadless pacemaker, including a header assembly having a monolithic controlled release device (MCRD) for therapeutic agent elution, is described. The MCRD is in fluid communication with a space between an insulator and an electrode of the header assembly to elute therapeutic agent into the space when the leadless biostimulator is implanted. The therapeutic agent can elute through the space around the electrode to provide controlled elution of the therapeutic agent to a surrounding environment. The electrode can extend longitudinally through the insulator cavity to a distal tip that provides a stable surface area and controlled impedance for pacing a target tissue. Other embodiments are also described and claimed.

Abstract: The present disclosure provides a transcutaneous energy transfer system (TETS), having an implantable receiving coil in communication with an implantable controller and a hermetically sealed package encased by the implantable receiving coil. The hermetically sealed package including a plurality of tuning capacitors, at least one temperature sensor, scavenging circuitry configured to scavenge power from the plurality of tuning capacitors, and a temperature measuring circuit in communication with the at least one temperature sensor and the scavenging circuitry. The at least one temperature sensor being configured to measure a temperature of the hermetically sealed package and the temperature measuring circuit being configured to transmit the measured temperature to the implantable controller.

Abstract: A method is provided for performing electromagnetic radiation therapy on a subject. The method comprises providing a device which emits electromagnetic radiation, wherein the electromagnetic radiation includes a first portion that oscillates between at least first and second distinct states, and a second non-oscillatory portion; and illuminating the subject with the electromagnetic radiation.

Abstract: Methods, Apparatuses, and Systems of operating a laser atherectomy system to perform an endoscopic atherectomy procedure within a vessel at a therapeutic region of an anatomical condition by use of an atherectomy laser device coupled to an ultrasound imaging probe. The atherectomy laser device operates to generate photoacoustic signals from a light source of the atherectomy laser device to for guidance within the vessel and to characterize tissue about the therapeutic region by delivery of pulsed wavelengths within the vessel, and to perform operations of tissue ablation directed to the anatomical condition. This enables guidance of the atherectomy laser device by feedback from the viewing of photoacoustic images based on photoacoustic signals generated the atherectomy laser device and created in response to changes in acoustic intensity due to changes of optical wavelength monitored by the ultrasound imaging probe.

Abstract: A physiological monitoring system can use physiological wearable monitors to collect and/or detect various parameters, such as cough, wheeze, heart rate, skin temperature, activity, respiration rate, skin impedance, electro-cardiogram data, blood pressure, galvanic skin response, and the like. One or more of these parameters, or other such parameters, may be used in methods in the fields of lung cancer, physiotherapy, monitoring disabled or challenged individuals, monitoring end of life conditions, monitoring breathing gas usage, monitoring patients and individual wellness, data acquisition, athletic sports monitoring, athletic sports entertainment, virtual reality feedback, telemedicine, hospital aid, illness detection and its severity, and public service, as examples. Such methods can use data from one or more wearable devices with the appropriate data processing to present the user or healthcare provider with the appropriate analysis.

Abstract: A system, a wearable device, and a method are provided which can increase the accuracy of physiological metrics while detecting if the patient ingested digital medicine and/or improve performance of the wearable device. The wearable device can comprise machine executable instructions that when executed by the processor, cause the processor to perform various algorithms, such as, for example, at least one of a step count algorithm, a body angle algorithm, a heart rate algorithm, a peak finder algorithm, an adaptive thresholding algorithm, a heart rate variability algorithm, a R-R cleaning Algorithm, a deltaR-R cleaning algorithm, a merge twin interval algorithm, a split tall intervals algorithm, an absorb short intervals algorithm, a bimodal detection algorithm, and a resting algorithm.

Abstract: Methods and systems for proving spinal cord stimulation (SCS) for treating pain in a patient are described. Embodiments of the described methods and systems can provide sub-perception SCS that has a fast wash-in time by using stimulation parameters that activate surround inhibition in the patient. Measuring retrograde potentials evoked by the stimulation can be performed to facilitate choosing the best stimulation parameters, in particular, the best stimulating electrode contact configurations for activating surround inhibition. For example, peripheral electrodes may be placed at the center of the patient's pain (within a local receptive field (LRF), with respect to the patient's pain center) and within an area surrounding the patient's pain center (within a surrounding receptive field (SRF), with respect to the patient's pain center). Retrograde evoked potentials measured and the SRF and/or the LRF can be used to guide the selection of the stimulation parameters.

Abstract: Systems and methods are directed to influencing organ function by stimulating the dorsal root ganglion. Systems include at least one electrode to deliver electrical stimulation to the dorsal root ganglion to activate afferent nerves innervating at least one organ, and computing apparatus comprising one or more processors operably coupled to the at least one electrode to control the electrical stimulation.

Abstract: A system and method for noninvasive sleep monitoring are disclosed. The system includes an in-ear biosensor system (“biosensor system”) and a data analysis system. The biosensor system includes at least one earbud placed at or within an ear canal of an individual. The earbud includes an acoustic sensor that detects biosignals including infrasonic and audible signals from the individual in the ear canal. A controller board of the biosensor system collects and forwards the biosignals to the data analysis system. The data analysis system analyzes the biosignals to identify and monitor physiological information of the individual during sleep. The physiological information includes sleep stages, sleeping position information, sleep events including snore, breathing cessation and bruxism events, and sleep disorders, in examples. The system can also induce changes to the physiological information during sleep using external stimuli to improve a quality of sleep.

Abstract: Provided is an electrocardiogram lead guide system. The electrocardiogram lead guide system may include: an electrocardiograph attached to a part of a body of a patient and acquiring posture information and electrocardiogram signals using a plurality of sensors; and a user terminal providing guide information for guiding the attachment direction of the electrocardiograph based on the posture information.

Abstract: An apparatus for medical treatment includes a probe including multiple electrodes and configured to be inserted in a body cavity of a patient so as to bring the multiple electrodes into contact with tissue in the body cavity. A processor is configured to assess one or more individual contact quality indicators with respect to the contact between each of the multiple electrodes and the tissue, to compute one or more global contact quality measures based on the individual contact quality indicators of the multiple electrodes, to compare the one or more global contact quality measures to a predefined global contact quality criterion, and to display on a display screen an icon indicating whether the global contact quality measures satisfy the predefined global contact quality criterion.

Abstract: Systems and methods are provided for monitoring a wellness of a user. A wellness-relevant parameter representing the user is monitored at a portable device over a defined period to produce a time series for the wellness-relevant parameter. A first set and a second set of either cognitive assessment data or psychosocial assessment data are obtained for the user at respective first and second times in the defined period. A value is assigned to the user via a predictive model according to the time series for the wellness-relevant parameter, the first set of either cognitive assessment data or psychosocial assessment data, and the second set of either cognitive assessment data or psychosocial assessment data.