Abstract: A syringe adapter includes a housing having a first end and a second end with the first end configured to be secured to a first container, a cannula having a first end and a second end with the second end positioned within the housing, and a collet having a first end and a second end with at least a portion of the collet received within the housing. The collet includes a body defining a passageway, a seal member received by the passageway, and an arcuate, resilient locking member connected to the body of the collet. The collet is movable from a first position where the locking member is open to receive a mating connector to a second position where radially outward movement of the locking member is restricted.

Abstract: A multi-stage system for warming blood that enables safe and rapid blood transfusions in the field. The first stage of the system is a rapid blood warming device that heats blood quickly from cold storage to body temperature. This stage may use a high-energy power source, such as AC power, that is available in a facility such as a hospital. The second stage is a portable heated blood transport device into which heated blood bags are placed for transportation to a patient. This device keeps the blood bags warm using battery power. Because blood bags are pre-heated with the rapid warming device, the transport device can be lightweight and portable. An optional third stage is a transfusion temperature regulating device that boosts the final temperature of blood just before it enters the patient. All three devices may have sensors and controllers that maintain blood temperature within desired ranges.

Abstract: A heat exchanger for a blood circulation circuit includes a hollow fiber membrane layer having a plurality of laminated hollow fiber membranes 31. Each of the hollow fiber membranes 31 has a barrier layer 5 having a hydrogen peroxide barrier property, and the barrier layer 5 has an oxygen permeability coefficient of 6 cc·cm/m2·24 h/atm or less at 25° C.

Abstract: A dual chambered syringe includes: an inner barrel defining a first inner chamber, the inner barrel having an apertured stopper at its distal end, the inner barrel being open at its proximal end; a shaft adapted to fit within the inner barrel, the shaft having a distal end which is engageable with the aperture of the stopper; a device for controlling engaging and disengaging of the distal end of the shaft with the aperture of the stopper; an outer barrel concentric with the inner barrel defining a second inner chamber, the outer barrel having a distal end for receiving and dispensing fluids and a proximal end into which the distal end of the inner barrel is insertable into the second inner chamber; the apertured stopper engages the second inner chamber of the outer barrel and selectively prevents or permits the passage of fluids between the outer barrel second chamber and the inner barrel first chamber; the inner barrel having an engageable surface on its outside surface; and, the outer barrel having operativ

Abstract: The present disclosure is for the patients who are not capable of going to the bathroom and not able to urinate physically, and being confined to bed; it relates to a waste disposal unit as functional underpants enabling the disposal of solid-liquid wastes of said patients in an autoregulatory manner, providing a full-hygienic cleaning for the person by means of adhering and contacting methods, and separately designed for males and females.

Abstract: An ophthalmic solution discharging apparatus is described. The ophthalmic solution discharging apparatus comprises: a base portion comprising a cylindrical base for receiving and removably engaging a dropper of an ophthalmic solution container; a head portion comprising a micro nozzle portion through which ophthalmic solution is discharged, a shield portion that cylindrically surrounds the micro nozzle portion, the shield portion comprising a wall containing an opening for viewing a portion of the micro nozzle portion during discharge; a neck portion that connects the base portion and the head portion; and an internal cavity portion defined by the base, head and neck portions and comprising a (1) container engagement portion for receiving and removably engaging the ophthalmic solution container, and (2) a funnel portion for transporting and discharging ophthalmic solution through the micro nozzle portion at a lesser volume than would otherwise be discharged by the dropper of the ophthalmic solution container.

Abstract: The device of the present invention includes a dual chamber gas exchanger that is configured for increased flexibility and scalability for many clinical applications. The dual chamber oxygenator can be configured and used in various applications, such as in a heart-lung machine for cardiopulmonary support during cardiothoracic surgery, in an extracorporeal membrane oxygenation (ECMO) circuitry, as a respiratory assist device for patients with lung failure, and the like. The dual chamber gas exchanger features two sweep gas flow paths and two gas exchange membrane bundles enclosed in a housing structure with various blood flow distribution and gas distribution mechanisms. The gas exchanger includes an outer housing, an intermediate housing, two gas exchange fiber bundles, a blood inlet, a blood outlet, two gas inlets, two gas outlets, two gas distribution chambers and an optional heat exchanger.

Abstract: A dressing assembly for use with a reduced pressure treatment system, the dressing assembly develops a directed force under reduced pressure. The directed force may be a radial force or a closing force. The dressing assembly includes a shaped dressing bolster having a shaped extremity that is operable to evenly deliver the radial force and to distribute reduced pressure. Numerous shapes may be used for the shaped extremity. The dressing assembly may further include an over-drape to assist in creating a seal over the shaped dressing bolster and against a portion of a patient's epidermis.

Abstract: A pulmonary artery (PA) via trans-septal to left atrial (LA) percutaneous dual lumen cannulation system which reduce the pressure of the right ventricle provides drainage of pulmonary artery blood with bypassing the lung while return the blood to the Left Atrium (LA) without the need for thoracotomy for a wearable pump less extra corporeal lung assist (pECLA) to remove CO2, pump less extra corporeal membrane oxygenation (ECMO), para-corporeal pump driven CO2 removal, extra corporeal CO2 removal (ECCO2R) pump driven, para-corporeal pump driven membrane oxygenation, or extra corporeal membrane oxygenation (ECMO) with extra-corporeal pump. By establishing percutaneously a shunt with a dual lumen cannula between PA and LA using the PA-LA pressure gradient as the driving force for the blood flow through the drainage lumen, CO2 removal device, or oxygenator and return cannula lumen in the vascular system.

Abstract: An apparatus for tissue therapy may include a sequentially-collapsing tissue interface for use with negative pressure. The apparatus may include a first manifold and a second manifold fluidly coupled to the first manifold through a constricted fluid path. A fluid conductor may fluidly couple the second manifold to the first manifold. The fluid conductor may constrict fluid flow between the first manifold and the second manifold. The apparatus may include a negative-pressure source fluidly coupled to the first manifold in some embodiments. A controller may be configured to operate a negative-pressure source to provide negative pressure to a tissue interface in a therapy sequence adapted to propagate a wave in the tissue site. Such motion may be particularly advantageous or beneficial for a variety of conditions, including lymphedema, edema, or venous insufficiency.

Abstract: Systems and methods are provided for determining an estimated risk of arrhythmia during or after dialysis based on changes in serum potassium concentration of a patient and an amount of fluid removed from the patient during dialysis. The systems and methods allow for a determination of a risk that arrhythmia will occur due to the changes in potassium and fluid volume of a patient during dialysis, and for optimizing a dialysis prescription in order to minimize the risk of arrhythmia.

Abstract: An apparatus for providing dialysis is described. The apparatus is a patch which provides structural support to a blood vessel, such as vein or fistula. The patch provides a location for puncturing the blood vessel with a needle, either at the puncture site or on the back side to prevent the needle from going through the blood vessel. The patch may also be palpated, allowing health care provider to easily locate a preferred puncture site.

Abstract: A female catheter assembly for a discrete and comfortable solution to female urinary incontinence includes a collection unit having a partially cylindrical collection area and an inner band coupled around a perimeter of the collection area. The collection area is configured to cover from above a user's vagina to a user's perineum. A cover extends from a right side, a top side, and a left side of the inner band and an outer band is coupled to a perimeter of the cover. An inner surface of the collection unit has an adhesive coupled from the inner band to the outer band. The collection area has a drain aperture adjacent a bottom side. A hose extends from a drain port coupled to the drain aperture to a collection bag. A release tube is coupled to a lower aperture of the collection bag and a clamp is selectively engageable with the release tube.

Abstract: An object is to provide a blood purifying device and an access flow rate measuring method enabling easy and accurate measurement of an access flow rate of an access vessel. A blood purifying device includes a flow rate calculating unit calculating the access flow rate of an access vessel based on an initial blood indicator for blood distributed through a vein side circuit and flowing through the access vessel of a patient, the flow rate distributed through measuring means when a pump is reversed to cause the priming solution to flow out from an artery side circuit, and a blood indicator for the blood diluted with the priming solution which is obtained when the pump is reversed to dilute, with the priming solution, the blood distributed through the vein side circuit.

Abstract: A cannula for the circulation of a fluid in an artery, includes a main lumen conveying a volume of fluid towards a first distal end; an accessory lumen including at least one inner portion arranged inside the main lumen, including: a proximal end situated downstream from the proximal end of the main lumen so as to capture a fraction of the flow of fluid entering the main lumen; a bent portion modifying the direction of flow of the fluid flow captured by the accessory lumen with respect to the direction of flow of the fluid emerging from the first end; a second distal end situated upstream from the first distal end of the main lumen, emerging on a side opening of the cannula so as to direct the captured fraction of liquid in the modified direction of flow.

Abstract: Systems and methods for delivering multiple ocular implants to reduce intraocular pressure are disclosed. The ocular implants can be implanted at multiple sites within a single human eye without requiring removal of the delivery apparatus from the eye. A system for delivering multiple ocular implants can include a plurality of implants, an external housing, and an introducer assembly. The external housing can provide access to an implant singulation actuator and an implant delivery actuator. The introducer assembly can comprise an auto-retracting introducer portion. The delivery apparatus can include an infinite activation mechanism/portion and/or a manual singulation mechanism/portion.

Abstract: A method and apparatus are disclosed for dressing a wound. The apparatus comprises an absorbent layer for absorbing wound exudate, a liquid impermeable, gas permeable filter layer over the absorbent layer, a cover layer comprising at least one orifice and a first liquid and gas permeable transmission layer underlying the absorbent layer. The transmission layer is in fluid communication with the filter layer.

Abstract: A heat exchanger for an oxygenator device has multiple hollow fiber membranes that each have a hollow portion through which a heat medium passes, wherein the fibers are wound as a cylinder body. Each of the hollow fiber membranes follows a path between opposing ends of the cylinder body which is tilted with respect to a central axis of the cylinder body and is wound around the central axis of the cylinder body, wherein a tilt angle ? with respect to the central axis ranges from 22° to smaller than 67°, and wherein a constituent material of each of the hollow fiber membranes has a Young's modulus E ranging from 2.6 GPa to 0.07 GPa. During winding, the hollow fiber membranes are stretched according to a stretching rate between 0.5% and 3.0% and then fixed at the ends to maintain the stretching.

Abstract: Systems, devices and methods for draining and analyzing bodily fluids are disclosed in which a drainage assembly is configured to prevent negative pressure build-up. The drainage assembly generally includes a catheter which may include a drainage lumen, a reservoir, a venting mechanism in fluid communication with the drainage lumen and a positive pressure lumen, and a controller. The venting mechanism may further include a valve which is configured to maintain a closed position, as well as a vent in fluid communication with the valve, where the venting mechanism is configured to inhibit wetting of the vent from fluid within the drainage lumen.

Abstract: A method and apparatus are disclosed for dressing a wound. The apparatus comprises an absorbent layer for absorbing wound exudate, a liquid impermeable, gas permeable filter layer over the absorbent layer, a cover layer comprising at least one orifice and a first liquid and gas permeable transmission layer underlying the absorbent layer. The transmission layer is in fluid communication with the filter layer.