Abstract: The present invention provides a liquid composition for defoliation of crop plants comprising a metal chlorate and alkali metal halide. The invention also provides a process for preparing the liquid composition for defoliation of crop plants and a method of defoliating crop plants.

Abstract: The invention provides antibiotic combination therapies for treating an A. baumannii infection in a subject. The combination therapies include rifabutin and a second antibiotic, such as colistin and cefiderocol.

Abstract: The present invention relates to a powder mixture, in particular for the remineralization of teeth, a powder jet device, in particular for application in the field of dentistry, a use of the powder mixture for producing a means for the remineralization of teeth 5 and to a method for the remineralization of teeth, and a use of a powder mixture in a dental apparatus. The powder mixture comprises a deposition powder which is designed to adhere to tooth surfaces.

Abstract: In one aspect, a method of treating smokeless tobacco addiction comprising administering to an individual in need thereof a pharmaceutical composition comprising nicotine, a therapeutically effective amount of cannabidiol, and a pharmaceutically acceptable vehicle therefor. In some aspects, the composition is administered transmucosally, such as in an oral dosage form or nasal spray. In other aspects, the composition is administered transdermally. In another aspect, a chewable gum contains nicotine in at least a base portion and cannabidiol in at least an outer portion thereof.

Abstract: A non-sticky body surface patch is provided, which is attachable on a body surface to add a look of fullness to the body surface, exhibits excellent followability to skin deformation, and imposes little burden on body surfaces and thus is widely applicable to body surfaces. The non-sticky body surface patch includes a silicone rubber having a thickness in the range from 50 to 600 ?m, wherein the silicone rubber consists of a silicone rubber composition having a rubber hardness of 20 or less measured with a Type A durometer as defined in JIS K6249 standard.

Abstract: 5-alkylthio-7-[(4-arylbenzyl)amino]-1(2)H-pyrazolo[4,3-d]pyrimidine derivatives of formula I that are effective inhibitors of kinases and exhibit strong antiproliferative and proapoptotic properties on lymphoma cells. Derivatives in the treatment of blood hyperproliferative diseases, such as Non-Hodgkin lymphomas are also disclosed.

Abstract: An oral care composition comprising zinc phosphate, stannous fluoride, arginine or lysine and an organic acid buffer system, as well as methods of using the same.

Abstract: An object is to provide a cosmetic composition that: has a high soft focus effect, a high skin beautifying effect, and a high moisture retaining effect; is safe; and enables reduction in environmental impact. Yeast cell wall particles retaining shapes of yeast cell walls and having an average particle diameter ranging from 1 to 25 ?m are prepared and blended in a cosmetic composition.

Abstract: The present invention relates to an amphiphilic block copolymer composition which provides enhanced stability to a micelle formed by an amphiphilic block copolymer in an aqueous phase.

Abstract: A method for modulating metabolism is provided which includes the step of providing a consumable composition including an extract containing a compound of Formula I to a subject in need thereof thereby modulating the subject's metabolism and addressing the underlying pathogenesis of metabolic disorders, such as nonalcoholic fatty liver disease, nonalcoholic steatohepatitis and type II diabetes mellitus.

Abstract: Methods of producing supramolecular structures using molecular recognition and methods of controlling the size of the nanoparticles produced to form discrete particles. Pharmaceutical formulations of the supramolecular structures for viral infections treatments. Supramolecular nanoparticles may comprise combinatorial carboxylated cobalamins; combinatorial carboxylated dipyridamoles; and basic amino acid polypeptides. The supramolecular nanoparticles are dynamic self-organizing soluble nanostructures which have a plurality of binding components, organic cores, and terminating components. The binding components include combinatorial carboxylated cobalamins with binding regions. The organic cores include combinatorial carboxylated dipyridamole adapted to bind to the combinatorial carboxylated cobalamins such that the organic cores can provide a mechanical structure for the self-organizing soluble nanostructures and a first type of inclusion complexes.

Abstract: A pain relief device and method or system to aid in the resolution of pain in a body including at least one layer of PVDF film and at least one other layer for directional purposes, as well as a polarizing layer. The device can be packaged in various ways.

Abstract: A pain relief device and method or system to aid in the resolution of pain in a body including at least one layer of PVDF film and at least one other layer for directional purposes, as well as a polarizing layer. The device can be packaged in various ways. Also described is a device that uses a combination of LED bulbs, polymer based materials and a near field accelerator to provide pain relief.

Abstract: A unit multiparticulate dosage form for delivering one or more basic, active pharmaceutical ingredients into the body in need of such medications to achieve target PK (pharmacokinetics) profiles is described. The dosage form comprises one or more multicoated drug particles (beads, pellets, mini-/micro-tablets) having a barrier coating and a lag-time coating. Each Timed Pulsatile Release (TPR) bead population exhibits pre-determined lag-time followed by differing release characteristics. The composition and thickness of the barrier coating, composition and thickness of the lag-time coating, ratio of IR beads to one or more TPR bead populations and total dose may be varied depending on the alkalinity, pH-dependent solubility and elimination half-life of the active ingredients to achieve target PK profiles (suitable for a once or twice daily dosing regimen) in patients in need of such medications.

Abstract: The present invention relates to a comprising (A) an active ingredient which is hardly soluble in water, but soluble in a C1-4 lower alcohol that may contain 30 vol % or less water, (B) polyvinyl alcohol having a saponification rate of 55-99%, and (C) a non-ionic surfactant, wherein the (A) active ingredient has a mean particle size of 10-300 nm, and a process thereof.

Abstract: Plant-based medicinal compounds or nutritional supplements in various carrier combinations are described. The carriers can include N-acylated fatty amino acids, penetration enhancers, and/or various other beneficial carriers. The plant-based composition/carrier combinations can create administration benefits.

Abstract: At present, the most prevalent pharmaceutical dosage forms, the oral immediate-release tablets and capsules, are granular solids. The problem of such solids is that their microstructure and properties are not predictable from physical models. As a consequence, product development and manufacture are resource-intensive and time-consuming, and quality control is statistical by testing instead of by design. Furthermore, the range of the drug release rate, and the variety of active ingredients that can be processed to a functional product, are limited in such dosage forms. Presented herein, accordingly, is a fibrous dosage form suitable for immediate-release applications prepared by a predictable liquid-based process. The fibrous dosage form includes a drug-containing solid comprising a three dimensional structural network of one or more drug-containing fibers.

Abstract: Provided is a repellent material capable of maintaining a stable repelling effect for a long period of time. A pest repellent material of the present invention includes porous particles including primary particles forming pores and aggregating, and an insect repellent component present in the pores. The primary particles contain silica as a component, and in an infrared absorption spectrum of the pest repellent material, a ratio (I1/I2) of the maximum absorbance (I1) at 3730 to 3750 cm?1 to the maximum absorbance (I2) at 1160 to 1260 cm?1 is 0.005 or less. A contact angle of the porous particles with water is greater than 90°, and the contact angle of the porous particles with the insect repellent component is 1° to 90°. It is preferred that 2 to 5 ml of the insect repellent component is contained based on 1 gram of the porous particles.

Abstract: Methods of treatment of NTM lung infections using formulations of liposomal ciprofloxacin. Specific liposome formulations and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.

Abstract: The present invention relates to the compound [2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl]ethanoate (Nitazoxanide) or 2-hydroxy-N-(5-nitro-2-thiazolyl)benzamide (Tizoxanide) for treating cholestatic and fibrotic diseases.