Patents Examined by Benjamin R Whatley
  • Patent number: 11506678
    Abstract: An automatic analysis apparatus and an operating method for the automatic analysis apparatus. At least two magnetic separation units are introduced, each magnetic separation unit operating independently and being used for performing magnetic separation cleaning on a reaction solution in a reaction cup. Each magnetic separation unit may be used for any magnetic separation cleaning step in a one-step test project or a multi-step test project, thereby significantly increasing the test speed and the test throughput of the automatic analysis apparatus.
    Type: Grant
    Filed: March 20, 2020
    Date of Patent: November 22, 2022
    Assignee: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Wentao Ju, Chongdong He, Jun Wang, Yanwen Weng, Chuanfen Xie
  • Patent number: 11504753
    Abstract: A cleaning module, a sample analyzer with the cleaning module and a cleaning method. Wherein, the cleaning module may include a disk body assembly and a cleaning assembly. The disk body assembly may include a disk body, the cleaning assembly and the disk body may move relatively, and the disk body and the cleaning assembly complete extraction of waste fluid and cleaning on a path of moving relatively.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: November 22, 2022
    Assignee: Shenzhen New Industries Biomedical Engineering Co., Ltd.
    Inventors: Liang Zhu, Shuai Tong, Wanguan Yi, Li Yin, Yi Hu, Dingping Ban
  • Patent number: 11506578
    Abstract: A smear system includes smear preparing apparatus that prepares a smear slide and a smear transporting apparatus that transports the smear slide to a smear-image capture apparatus. The smear preparing apparatus includes: a smear preparation part that smeares a sample on a slide; and a smear arrangement part that places smear slides in a smear container. The smear transporting apparatus includes: a smear-container transport part that transports the smear container with the smear slides; an identification-information acquisition part that acquires identification information on whether image capturing by the smear-image capture apparatus is necessary, from each of the smear slides accommodated in the smear container positioned on a transport path of the smear-container transport part; and a smear transfer part that transfers the smear slide whose image is to be captured to the smear-image capture apparatus on the basis of the identification information acquired by the identification-information acquisition part.
    Type: Grant
    Filed: July 28, 2017
    Date of Patent: November 22, 2022
    Assignee: SYSMEX CORPORATION
    Inventors: Takayuki Nakajima, Tetsuya Oda, Hiromi Onomichi, Kentaro Tsurumi, Seiya Shinabe
  • Patent number: 11506577
    Abstract: An automated tape transfer apparatus including a tape feed mechanism feeding a continuous length of an adhesive tape through the automated tape transfer apparatus and a tape applicator applying the adhesive tape to a cutting face of a sample block, wherein a section of the sample block is adhered to the adhesive tape after cutting of the section from the sample block. A slide station transfers the cut section from the adhesive tape to a slide.
    Type: Grant
    Filed: January 30, 2020
    Date of Patent: November 22, 2022
    Assignee: Clarapath, Inc.
    Inventors: Cong Zhang, Mark Fasciano, Partha P. Mitra
  • Patent number: 11506579
    Abstract: An assembly for forming a microchamber for an inverted substrate is disclosed. The assembly can include a body having a chamber formed therein. A dispensing cavity can be provided to supply a reagent to the chamber. A slide support structure can be configured to support the slide such that the tissue sample faces the chamber when the slide is mounted to the slide support structure. The chamber and the slide support structure can be dimensioned such that, when the reagent is supplied to the dispensing cavity, the reagent is drawn to the chamber by way of capillary forces acting on the reagent.
    Type: Grant
    Filed: March 23, 2020
    Date of Patent: November 22, 2022
    Assignee: BioGenex Laboratories, Inc.
    Inventor: Krishan L. Kalra
  • Patent number: 11498076
    Abstract: Methods of pre-heating a test vessel prior to transfer of the test vessel to an incubator may shorten an incubation cycle, ensure proper temperature of a test specimen in the test vessel, and/or improve testing accuracy and/or throughput in a bio-liquid specimen testing apparatus. The methods include providing a test vessel pre-heating apparatus having a receptacle sized to receive a test vessel therein and having at least one heating unit configured to heat by direct conduction at least one side of the test vessel. The methods also include heating at least one side of the test vessel via direct contact using the at least one heating unit. Specimen testing apparatus and test vessel pre-heating apparatus configured to carry out the method are described, as are other aspects.
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: November 15, 2022
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Paul Dulaff, Christopher Delametter
  • Patent number: 11498070
    Abstract: Microfluidic devices having a construct formed from perfluoropolyether and poly(ethylene glycol) diacrylate. The construct includes an inlet for receiving a continuous phase fluid, an inlet for receiving a dispersed phase fluid, and a plurality of channels extending through the construct. The plurality of channels are in fluid communication with both the inlet of the continuous phase fluid and the inlet of the dispersed phase fluid. The construct further includes a plurality of microdroplet generators configured to produce microdroplets, each of the microdroplet generators in fluid communication with the plurality of channels. Additionally, the construct includes an outlet formed in the construct and in fluid connection with the plurality of microdroplet generators.
    Type: Grant
    Filed: March 21, 2019
    Date of Patent: November 15, 2022
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Daeyeon Lee, David Issadore, Sagar Prasad Yadavali, Heon-Ho Jeong
  • Patent number: 11498068
    Abstract: A microfluidic device, a microfluidic detection assembly and a detection method for the microfluidic device. The microfluidic device includes a first substrate and a second substrate; the first substrate and the second substrate are oppositely arranged to define a channel between the first substrate and the second substrate, the channel is configured for liquid to flow, the first substrate includes a base substrate and a plurality of control assemblies which are arranged on the base substrate along an extending direction of the channel, each of the plurality of control assemblies includes: a first electrode, a second electrode and a plurality of coils, and the first electrode is configured to input currents into the plurality of coils, and the plurality of coils are connected in parallel to the second electrode.
    Type: Grant
    Filed: January 2, 2019
    Date of Patent: November 15, 2022
    Assignees: BEIJING BOE OPTOELECTRONICS TECHNOLOGY CO., LTD., Beijing BOE Technology Development Co., Ltd.
    Inventors: Wenliang Yao, Haochen Cui, Peizhi Cai, Yuelei Xiao, Fengchun Pang, Yue Geng, Le Gu, Nan Zhao, Hui Liao, Yingying Zhao, Chuncheng Che
  • Patent number: 11491481
    Abstract: A diagnostic tester for analysing a body fluid includes a test tape having test zones configured to receive the body fluid. The tester further includes a chamber configured to contain the test tape and a seal. The tester further includes an opening of the chamber which is at least partially bordered by the seal. The tester further includes a face on the chamber that borders the opening, at least part of the face being formed by the seal. The tester further includes a closing leaf spring sealed onto the face, the closing leaf spring shielding the opening from an environment outside the chamber. The tester further includes an exit gap formed between the closing leaf spring and the seal through which the test tape is configured to exit the chamber.
    Type: Grant
    Filed: June 2, 2018
    Date of Patent: November 8, 2022
    Inventor: Brandon Bransgrove
  • Patent number: 11491482
    Abstract: The present invention provides an extraction cassette, which includes an extraction module and a liquid receiving module. The liquid receiving module communicates with the extraction module. The liquid receiving module includes a receiving module body, a sample compartment, a sealing member, an alcohol compartment and a first path. The receiving module body includes a first side, a second side and a sample feeding hole. The sample compartment is formed on the receiving module body. The sample compartment communicates with the sample feeding hole, the sample compartment includes a first sample compartment connection hole and a second sample compartment connection hole. The sealing member is adapted to seal the sample feeding hole. The alcohol compartment is formed on the receiving module body. The alcohol compartment communicates with the first sample compartment connection hole of the first sample compartment via the first path.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: November 8, 2022
    Assignee: DELTA ELECTRONICS, INC.
    Inventors: Wei-Yu Chung, Song-Bin Huang, Shing-Lun Liu, Yu-Kai Kao, Yi-Chen Li
  • Patent number: 11480504
    Abstract: When the type is to be changed from serum (preceding sample) to urine (current sample), “serum” is set to a preceding type and “urine” is set to a measurement type at number 1 in a condition number. At condition number 1, the wash type is pattern 1, with washing performed once with detergent 1. Where the preceding sample is serum and the current sample is CSF, the condition number is 2 and the wash type is pattern 2, with washing performed twice using detergent 1 and once with detergent 2. Where the preceding sample is urine and the current sample is CSF, the condition number is 3 and the wash type is pattern 3, with washing performed once with detergent 1, once with detergent 2, and once with water. In the case of pattern 4, washing is performed three times with detergent 1.
    Type: Grant
    Filed: January 30, 2018
    Date of Patent: October 25, 2022
    Assignee: HITACHI HIGH-TECH CORPORATION
    Inventors: Naoto Suzuki, Yoshiaki Saito, Yoichi Aruga, Toshihide Orihashi, Kazuhiro Nakamura
  • Patent number: 11480526
    Abstract: A sample of water is tested for silica and phosphate content in a single apparatus. In the test method, a first sample of the water is colorimetrically analyzed in a reaction chamber using a “molybdenum blue” test in which silica and phosphate in the sample are complexed with a first reagent. The phosphate complexes are then optically inactivated by a second reagent and the color of the silica complexes is intensified with a third reagent. From this, the silica content is calculated. A further sample is colorimetrically analyzed without using the second reagent, so that a combined silica and phosphate content of the further sample is obtained. A value of the silica content is subtracted from the value of the combined silica and phosphate content, resulting in a phosphate content for the sample. The silica content and the phosphate content of the sample are reportable.
    Type: Grant
    Filed: January 21, 2020
    Date of Patent: October 25, 2022
    Assignee: Mettler-Toledo Thornton, Inc.
    Inventors: Robert Theriault, David Marsh, Anthony C. Bevilacqua, Jr.
  • Patent number: 11471883
    Abstract: A fluid chip suitable for a fluid device is disclosed in which an upper surface of a flow passage has another member bonded thereto. The disclosed fluid chip, in which a flow passage is formed, comprises a base material having a top surface forming at least a portion of a bottom surface of a flow passage, and a bonding member which is formed from an elastomer resin and an upper end surface of which is provided in a position higher than the top surface of the base material. The base material has a support post portion which projects from the top surface and defines the height of a side surface of the flow passage, and the support post portion of the base material is embedded in the bonding member.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: October 18, 2022
    Assignee: Enplas Corporation
    Inventors: Takumi Yamauchi, Nobuya Sunaga
  • Patent number: 11474118
    Abstract: A specimen transporting apparatus and method are provided, in which a specimen container having a non-printed region and a printed region on a side surface of the specimen container is rotated intermittently, each time through a certain angle, during a first rotation. Information printed on the printed region is read during the first rotation, and the location of the non-printed region is identified based on the success or failure of the reading. Next, a second rotation is performed, in which the specimen container is rotated continuously. The information printed on the printed region is read during the second rotation, and the location of the printed region is identified based on the success or failure of the reading. Accordingly, the location of an end portion of the printed region is identified, and the orientation of a specimen bar code is aligned relative to a transfer destination rack.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: October 18, 2022
    Assignee: Hitachi High-Tech Corporation
    Inventors: Shugo Okabe, Tatsuya Fukugaki
  • Patent number: 11474119
    Abstract: There is provided an automatic analysis device that can appropriately sort and discard expendable items. The automatic analysis device includes a common transport mechanism that transports a plurality of types of expendable items by common mechanism, a plurality of transport paths that is provided separately from the common transport mechanism, a type determination portion that determines the type of expendable item being transported by the common transport mechanism. The automatic analysis device controls to select one of a plurality of transport paths according to a determination result of the type determination portion and to transport the expendable items transported from the common transport mechanism via the selected transport path.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: October 18, 2022
    Assignee: HITACHI HIGH-TECH CORPORATION
    Inventors: Takahiro Kumagai, Takenori Okusa
  • Patent number: 11466268
    Abstract: A structured substrate includes a substrate body having an active side. The substrate body includes reaction cavities that open along the active side and interstitial regions that separate the reaction cavities. The structured substrate includes an ensemble amplifier positioned within each of the reaction cavities. The ensemble amplifier includes a plurality of nanostructures configured to at least one of amplify electromagnetic energy that propagates into the corresponding reaction cavity or amplify electromagnetic energy that is generated within the corresponding reaction cavity.
    Type: Grant
    Filed: December 21, 2020
    Date of Patent: October 11, 2022
    Assignee: ILLUMINA, INC.
    Inventors: M. Shane Bowen, Dajun Yuan
  • Patent number: 11467174
    Abstract: The purpose of the present invention is to constantly keep a state in a flow cell steady by filling a detection flow channel with a liquid. The configuration of the present invention for solving the aforementioned problem is as follows. Specifically, the present invention is an automatic analysis apparatus provided with a detection unit including a flow cell that accommodates a liquid serving as an analysis subject; a suction nozzle that is positioned upstream of the flow cell and that sucks the liquid to be introduced into the flow cell; a pump that is positioned downstream of the flow cell and that supplies the liquid to the flow cell; flow channels that connect the flow cell, the suction nozzle, and the pump; a power source; and a power-cutting instructing unit that gives an instruction to cut the power supply at least to the pump.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: October 11, 2022
    Assignee: Hitachi High-Tech Corporation
    Inventors: Yoshihiro Kabe, Yukinori Sakashita, Katsuhiro Kambara, Taku Sakazume, Tatsuya Fukugaki
  • Patent number: 11458234
    Abstract: A fluid cassette, for example, a blood treatment cassette having a cassette body embodied as a hard part and, optionally, a film which is connected to the hard part and at least partially covers the hard part, wherein the hard part comprises at least one first alignment device, and a second alignment device which are optionally arranged at first and second opposite sides of the fluid cassette or are attached thereon. The disclosure relates in addition to a blood treatment apparatus.
    Type: Grant
    Filed: September 30, 2019
    Date of Patent: October 4, 2022
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventor: Martin Lauer
  • Patent number: 11458476
    Abstract: An in-situ fecal specimen sampling device for stool tests, comprising: a sampling tube of a tube-like structure comprising an bottom with an opening; a sampling structure disposed inside the sampling tube is attached to the bottom of the sampling tube, and is an tube-like structure with a closed top end, an bottom end with opening and an stretchable soft body, which can insert a finger from the opening of the bottom outside the sampling tube and push forward and stretch the closed top end to beyond the sampling tube. The sample provider is able to collect the sample by placing the sampling structure onto the stool or inside the anus through the finger operated sampling structure by himself. All of the process can be finished during defecation process in-situ.
    Type: Grant
    Filed: October 17, 2019
    Date of Patent: October 4, 2022
    Inventor: Marvin Liu
  • Patent number: 11460377
    Abstract: Various embodiments directed to a work stand for holding a microscopic collection device for collecting a microscopic sample from a target surface, are provided. The work stand includes a first slit formed on a top surface of the work stand and capable of holding a first microscopic collection device comprising a first holding element and a first collection platform, wherein the first collection platform of the first microscopic collection device is perpendicular to the top surface. A second slit formed on the top surface of the work stand and capable of holding a second microscopic collection device comprising a second collection platform and a second holding element at an angle to the second collection platform perpendicular to the top surface of the work stand.
    Type: Grant
    Filed: March 17, 2020
    Date of Patent: October 4, 2022
    Assignee: THE MITRE CORPORATION
    Inventors: Michael Heath Farris, Kevin Robert Gemp, David Masters