Abstract: In an example system, multi-sensor motion data that reflects the motion of a user over a period of time is received as recorded by a plurality of motion sensors on wearable devices, specific changes are determined in the data by, firstly, quantifying it using a two-dimensional data transform; secondly, extracting an anomalous area; and thirdly, calculating a number of the anomaly's properties, and the results are input into a machine learning model to detect that the user fell. The machine learning model processes the anomaly's properties and evaluates the current state of the user's activity by classifying the properties against a state space previously calculated by analyzing historical activities of daily living. Depending on a two-dimensional transform implemented, the machine learning model detects when the user falls, as well as potentially allows predicting that the user will suffer a fall in advance of the actual event, aiming at solving the stroke prediction problem.

Abstract: Methods for the diagnosis, prognosis, patient stratification and prediction of pharmacological response in patients afflicted by psychiatric disorders based on electroretinography (ERG) parameters are described.

Abstract: Wearable uroflowmetry systems having wearable uroflowmeters are disclosed. A disclosed example uroflowmetry system comprises a wearable uroflowmeter including: a funnel portion having an end configured to secure the funnel portion against a person, an outlet opposite the end, and a funnel configured to capture urine excreted by the person when the end is secured against the person, and to direct the captured urine into the outlet; a fluid passage portion having an opening configured to receive the urine from the outlet of the funnel portion, and a fluid channel to pass the received urine along a length of the fluid passage portion; and a measuring portion having a sensor in the fluid channel configured to collect one or more measurements of the urine as the urine passes the sensor, the measurements representative of at least one of a property of the urine, or a flow characteristic of the urine.

Abstract: The neural health or state of a subject is assessed. A recording is obtained of a compound action potential arising in neural tissue of the subject. The recording is processed to determine whether a profile of the recorded compound action potential is anomalous, such as by exhibiting doublets, peak broadening or deformation, or other anomaly. An indication is output regarding the neural state of the subject based on determined anomalies in the recorded compound action potential.

Abstract: Pressure monitoring methods and systems for warning a patient or caregiver that soft tissue pressure has exceeded some predetermined level that over time would necessitate moving the patient to prevent or at least reduce a risk of soft tissue damage. The methods and systems entail the use of a pressure sensing unit adapted to be applied to or near a surface of the patient's body, and a sensor associated with the sensing unit to generate electrical outputs corresponding to soft tissue pressure sensed at the surface. The electrical outputs are wirelessly monitored over a preselected time period to generate a cumulative output signal based on the electrical outputs and corresponding to whether or not the soft tissue pressure has exceeded a predetermined pressure level during the preselected time period. An alarm is generated if the cumulative output signal exceeds a predetermined cumulative threshold until the soft tissue pressure drops below the predetermined pressure level.

Abstract: An evaluation apparatus includes a display; a gaze point detection unit configured to detect a position of a gaze point of a subject; a display controller configured to display an evaluation image including a main target image, sub target images, and an instruction information to gaze at the main target image; a region setting unit configured to set determination regions for the sub target images; a determination unit configured to determine whether the gaze point is present in the determination regions based on the position of the gaze point; an arithmetic unit configured to measure an arrival time from a predetermined time to a first arrival time of the gaze point at the determination regions based on a result of the determination unit; and an evaluation unit configured to obtain an evaluation data of the subject based on an average or a total value of the arrival times.

Abstract: A processing system is configured to obtain data indicating answers of a user of one or more hearing instruments to a questionnaire. Additionally, the processing system is configured to determine an initial audiogram based on the answers. Furthermore, the processing system is configured to perform an initial fitting of the one or more hearing instruments based on the initial audiogram.

Abstract: A biliary diagnostic device comprises a tubular body comprising an outer wall and an internal lumen, and a biliary diagnostic sensor comprising for analyzing biological matter in contact with the tubular body. A method of guiding an endoscope to a bile duct comprises inserting the endoscope into a duodenum, engaging a sensor with biological matter, electrically analyzing biological matter with the sensor to identify an electrical parameter, identifying liver bile in the biological matter from the electrical parameter, and guiding the endoscope through the duodenum based on the bile. A method of identifying biological matter comprises engaging a medical device sensor with biological matter in a bile duct, electrically analyzing biological matter with the sensor to identify an electrical parameter, identifying biological matter from a liver, pancreas or gall bladder from the electrical parameter, and outputting indicia of the biological matter to a user of the medical device.

Abstract: An intraocular pressure (IOP) includes a transmission film component, which is in direct contact with intraocular aqueous humor and configured to sense pressure fluctuations in the intraocular aqueous humor; a reflective film component set on an inner side of the transmission film component; and an adhesion layer component set on an inner layer of the reflective film component and configured to connect to an attachment device. An enclosed space formed by the reflective film component and the transmission film component constitutes a resonance chamber, which is filled with a filling medium. When a pressure in the intraocular aqueous humor is changed, the transmission film component is deformed, resulting in a change in a near-infrared (NIR) spectrum reflected by the reflective film component; the IOP is detected according to the change of the NIR spectrum.

Abstract: An intravascular system includes at least one pressure-sensing instrument sized and shaped for introduction into a vessel of a patient; a processing unit in communication with the pressure-sensing instrument, the processing unit configured to: obtain proximal pressure measurements for at least one cardiac cycle of the patient while the pressure-sensing instrument is positioned proximal of a stenosis of the vessel; obtain distal pressure measurements while the pressure-sensing instrument is positioned distal of the stenosis; select a diagnostic window within a cardiac cycle by identifying a change in sign of a slope associated with the proximal and/or distal pressure measurements, wherein the diagnostic window encompasses only a portion of the cardiac cycle of the patient; calculate a pressure ratio between the distal and proximal obtained during the diagnostic window; and output the calculated pressure ratio to a display device in communication with the processing unit.

Abstract: A method of operating an information processing apparatus may include collecting gait information of a walking assistance apparatus; determining a gait feature of a user of the walking assistance apparatus based on the collected gait information; and controlling the walking assistance apparatus by determining a gait group of the user based on the determined gait feature.

Abstract: Provided is a lancet which comprises: a housing provided with an inner sleeve guiding portion and a first needle core guiding portion; an inner sleeve provided inside the housing, wherein the front end of the inner sleeve has an inner sleeve needle outlet, and the inner sleeve is provided with a second needle core guiding portion; a needle core adapted to move axially along the first needle core guiding portion; a spring provided inside the housing to drive the needle core, wherein the inner sleeve guiding portion has a radial rotation angle at a rotation guiding section thereof away from the inner sleeve needle outlet; by pressing towards the inside of the housing, the inner sleeve is guided by the rotation guiding section to rotate such that the first needle core guiding portion is aligned with the second needle core guiding portion in the radial direction.

Abstract: A psychophysical method, system, and apparatuses to characterize visual symptoms. A method may include presenting one or more stimuli to a patient indicating one or more visual symptoms. The patient may produce one or more responses to the stimuli. A determination of a measure of visual symptoms of the patient may be made utilizing a Bayesian method based on the responses.

Abstract: The present invention relates to a collecting device (1) for sampling at least one specimen from bodily cavities of humans and animals, comprising: —an elongated flattened pouch (20) having: an open end (200), a top side (201) opposed to the open end (200), situated at a proximal end (101) of the collecting device (1), and two lateral sides (202, 204); and—two creasing means (32, 34), each having a fixed end (301), which is fixed inside the pouch (20) at or in the vicinity of said top side (201) and a free end (303), which protrudes freely through said open end (200), configured such that upon pulling the free ends (303) of the two creasing means (32, 34) in opposite directions, the short side (201) of the pouch (20) is brought closer to the open end (200) while the pouch (20) adopts a creased shape (22).

Abstract: A soleus contraction measurement system includes a sensor configured to measure rotational movement when positioned on a user's foot with an X-axis oriented laterally across the user's foot, a Y-axis oriented parallel to the user's foot, a Z-axis orthogonal to the X-axis and the Y-axis, and a positive X-axis rotational movement corresponding to an increasing ankle angle, and a memory storing computer-executable instructions for controlling a processor to: measure an X-axis rotational movement, identify a positive X-axis rotational movement as a plantarflexion and a negative X-axis rotational movement as an ankle dorsiflexion, deem the plantarflexion a performed soleus contraction when the plantarflexion is immediately followed by the ankle dorsiflexion for two consecutive cycles of plantarflexion and ankle dorsiflexion, and cause performance information regarding the performed soleus contractions to be communicated.

Abstract: A system for monitoring at least presence of a bioanalyte. The system comprises: a substrate having a skin contact surface, a microneedle outwardly protruding from the skin contact surface, a sensing complex positioned in the microneedle, and a circuit attached to the substrate. The sensing complex can comprise a nanostructure modified by a functional moiety covalently attached thereto, and an affinity moiety effective to react specifically with the bioanalyte to produce a reaction product. The circuit can apply voltage to the nanostructure and monitor changes in an electrical property of the nanostructure responsively to reaction between the reaction product and the functional moiety.

Abstract: Provided are a heart physiological parameter measurement method, device and terminal, and a computer storage medium. The method comprises: respectively obtaining back vibration information and shoulder vibration information of an object to be measured in a supine state by means of one or more shoulder vibration sensitive sensors and back vibration sensitive sensors; respectively generating first hemodynamic related information and second hemodynamic related information on the basis of the back vibration information and the shoulder vibration information, the second hemodynamic related information comprising right shoulder second hemodynamic related information generated from right shoulder vibration information; determining a reference AVC time point of an AVC event on the basis of the first hemodynamic related information; and determining an AVC feature point of the AVC event on the basis of the reference AVC time point and the right shoulder second hemodynamic related information.

Abstract: The embodiments disclose a method including receiving, with a first memory device, user profile data including demographics from at least from two persons, receiving specimen samples of personal tissue and pelvic fluid from the at least two persons, analyzing, with a first processor, the specimen samples to identify test results including hormones, infectious diseases, PH levels and genetic disorders, comparing, with a second processor, the test results to determine any correlation information with predetermined medical conditions data, converting, with a third processor, the correlation information into recommendation data for each person, and transmitting, with a platform communication device, the recommendation data to each person via a respective wellness app operating on a mobile device of each person.

Abstract: A tri-point tissue-collection needle configured similarly to a fine-needle-aspiration needle is configured to excise intact tissue cores for collection. The distal tip is configured with three beveled points separated by cutting edges, where a single longer/more distal point is trailed by and circumferentially separated from a symmetrical pair of points, providing a bilaterally symmetrical needle cannula distal end. A stylet may be provided through a lumen of the needle during introduction into a patient body, where the distal end surface of the stylet may be configured to complement the tri-point needle end configuration.

Abstract: Exemplary embodiments relate to systems, methods, and apparatus to objectively assess binocular dysfunction for screening, diagnoses, and evaluation of vision/oculomotor function before, during, and after various forms of therapeutic interventions. Systems and methods diagnose and assess binocular dysfunction objectively and automatically, can render a visual stimulus on one or more displays, and can control accommodative and proximal vergence stimulation of a user's eyes.