Patents Examined by Bethany Barham
  • Copolymers useful as rheology modifiers and home and personal care compositions comprising said copolymers
    Patent number: 9439848
    Abstract: The present invention relates to aqueous personal care, household care, and/or fabric care compositions comprising the instant copolymers. Also disclosed are methods for the rheological modification of aqueous personal care, household care, and/or fabric care compositions comprising the instant copolymers.
    Type: Grant
    Filed: August 27, 2009
    Date of Patent: September 13, 2016
    Assignee: BASF SE
    Inventors: Keith Graham, David Normington, Howard R. Dungworth, John M. Plonka
  • Methods and compositions for reducing Shiga toxin induced toxicity in mammals
    Patent number: 9439438
    Abstract: Manganese compositions effective in reducing Shiga toxin-induced toxicity in mammals infected with Shiga toxin-producing bacteria such as E. coli O157:H7 are described. Manganese compositions described herein can be combined with antibiotic therapy as manganese can block the toxic effects of Shiga toxin released from dying bacteria.
    Type: Grant
    Filed: January 18, 2012
    Date of Patent: September 13, 2016
    Assignee: Carnegie Mellon University
    Inventors: Adam D. Linstedt, Somshuvra Mukhopadhyay
  • Reinforced absorbable multilayered hemostatis wound dressing
    Patent number: 9439997
    Abstract: The present invention is directed to a reinforced absorbable multilayered hemostatic wound dressing comprising a first absorbable nonwoven fabric, a second absorbable woven or knitted fabric, thrombin and/or fibrinogen.
    Type: Grant
    Filed: April 10, 2006
    Date of Patent: September 13, 2016
    Assignees: Ethicon, Inc., Omrix Biopharmaceutical, Inc.
    Inventors: Anne Jessica Gorman, Sanyog Manohar Pendharkar, Guanghui Zhang, Liliana Bar, Israel Nur, Roberto Meidler
  • High strength chitin composite material and method of making
    Patent number: 9433698
    Abstract: The present invention is directed to a composite laminar material with high mechanical strength and methods of fabricating the material. The invention also provides a method of attaching a medical implant device to tissue.
    Type: Grant
    Filed: August 30, 2011
    Date of Patent: September 6, 2016
    Assignee: President and Fellows of Harvard College
    Inventors: Donald E. Ingber, Javier Gomez Fernandez
  • Compositions and methods to modulate the rate of EBIS production from dithiocarbamate fungicides
    Patent number: 9426985
    Abstract: New compositions and methods are described for modulating the rate of conversion of ethylene bisdithiocarbamate fungicides, such as mancozeb, into ethylene bis-isothiocyanate sulfide (EBIS).
    Type: Grant
    Filed: December 27, 2013
    Date of Patent: August 30, 2016
    Assignee: Dow AgroSciences LLC
    Inventors: Min Zhao, Lei Liu, J. Todd Mathieson, Robert J. Ehr, Maria E. Rodriguez Rosas
  • Deposition from surfactant systems
    Patent number: 9421401
    Abstract: The invention presented in this application relates to a fragrance deposition system for high surfactant applications such as shampoo and body wash. The system will provide a long lasting release of the fragrance and is more efficient at low levels and does not deposit particles that can cause adverse properties.
    Type: Grant
    Filed: April 12, 2010
    Date of Patent: August 23, 2016
    Assignee: AKZO NOBEL CHEMICALS INTERNATIONAL B.V.
    Inventors: Christine Puglisi, Daniel B. Solarek
  • Anterior segment drug delivery
    Patent number: 9421126
    Abstract: A therapeutic system comprises an ocular insert placed on a region outside an optical zone of an eye. The ocular insert comprises two structures: a first skeletal structure and a second cushioning structure. The first structure functions as a skeletal frame which maintains positioning of the implant along the anterior portion of the eye and provides support to the second, cushioning structure. This first structure maintains the attachment of the therapeutic system to the anterior portion of the eye for at least thirty days. In some embodiments the first structure remains a constant size and shape, e.g. a ring shape, a ring with haptics, or a curvilinear ring that is confined to and restrainingly engages the inferior and superior conjunctival fornices so as to retain the implant within the tear fluid and/or against the tissues of the eye.
    Type: Grant
    Filed: June 1, 2011
    Date of Patent: August 23, 2016
    Assignee: ForSight Vision5, Inc.
    Inventors: Yair Alster, Eugene de Juan, Jr., Cary J. Reich, Stephen Boyd, David Sierra, Jose D. Alejandro, K. Angela Macfarlane, Douglas Sutton
  • Methods of using polymeric compositions containing IR-emitting absorbing additives
    Patent number: 9421162
    Abstract: Polymeric compositions containing additives having properties of emission and/or absorption of radiation in the long infrared region, and articles shaped therefrom are produced, including yarns and textile articles such as fabrics or knits; such additives include organic additives or inorganic fillers which have a capacity for absorption/emission of radiation in the infrared region, in a wavelength range of from 2 ?m to 20 ?m, and also a polymeric substrate, with the proviso that the inorganic fillers may be selected from among oxides, sulfates, carbonates, phosphates and silicates, and such inorganic fillers having an average particle size of less than 2 ?m.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: August 23, 2016
    Assignee: RHODIA POLIAMIDA E ESPECIALIDADES LTDA
    Inventors: Thomas Canova, Dany Bizaroli De Mendonca, Tarcis Cordeiro Bastos
  • Pharmaceutical formulations
    Patent number: 9415013
    Abstract: Disclosed herein are pharmaceutical compositions comprising a plurality of first beads each comprising: a core; a first layer comprising pilocarpine or a pharmaceutically acceptable salt thereof; and a second layer comprising a first polymer. Also disclosed are pharmaceutical compositions comprising a plurality of second beads each comprising: a core; and a first layer comprising tolterodine or a pharmaceutically acceptable salt thereof. Further disclosed are pharmaceutical formulations comprising: a) a plurality of the first beads; b) a plurality of the second beads; or c) a plurality of the first beads and a plurality of the second beads.
    Type: Grant
    Filed: April 1, 2011
    Date of Patent: August 16, 2016
    Assignee: TheraVida, Inc.
    Inventors: Mehdi Paborji, Robert V. Tuohy, III, Peter R. P. Freed, Roger S. Flugel
  • Compositions and methods for treatment of neoplastic disease
    Patent number: 9415061
    Abstract: The present invention is concerned with immunostimulant compositions, in particular compositions comprising microparticulate form of murmyl dipeptide, and their use in the treatment of neoplastic disease.
    Type: Grant
    Filed: April 1, 2009
    Date of Patent: August 16, 2016
    Assignee: Innate Immunotherapeutics Limited
    Inventors: Frank B Gelder, Gillian Alison Webster
  • Cosmetic sponge and method for providing a cosmetic sponge
    Patent number: 9403953
    Abstract: This invention relates to a cosmetic sponge and a method of providing a cosmetic sponge incorporating a non-denatured collagen and other additives for skin care, cleaning, and cosmetic application.
    Type: Grant
    Filed: October 2, 2012
    Date of Patent: August 2, 2016
    Assignee: Diversified Global Technologies, LLC
    Inventor: Wayne Celia
  • Core-shell particle formulation for delivering multiple therapeutic agents
    Patent number: 9402918
    Abstract: A core-shell particle formulation for delivering multiple therapeutic agents is disclosed. More particularly, core-shell particle formulation configured to independently release therapeutic agents from the core and the shell. Moreover, the core-shell particle bearing therapeutic agents enables treatment against the diseases such as cancer, inflammatory and auto-immune diseases.
    Type: Grant
    Filed: August 21, 2014
    Date of Patent: August 2, 2016
    Assignee: Amrita Vishwa Vidyapeetham
    Inventors: Manzoor Koyakutty, Parwathy Chandran, Archana P. R., Shantikumar Nair
  • Macroporous 3-D scaffolds for tissue engineering
    Patent number: 9402710
    Abstract: Macroporous 3-D tissue engineering scaffold comprising elastomeric cross-linked polymer units and interconnected macropores containing living cells are produced by step of: in a mixture of the cells and elastomeric polymer units comprising activatable crosslinking groups, activating the crosslinking groups to form the scaffold.
    Type: Grant
    Filed: July 16, 2013
    Date of Patent: August 2, 2016
    Assignee: THE BOARD OF TRUSTEES FOR THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Fan Yang, Li-Hsin Han, Xinming Tong
  • Broad spectrum root canal filing composition for endodontric usage
    Patent number: 9399003
    Abstract: Disclosed is dental root canal filling (intracanal medicament) compositions that are effective against resistant root canal infections caused by Enterococcus faecalis and Vancomycin-resistant Enterococci.
    Type: Grant
    Filed: September 17, 2012
    Date of Patent: July 26, 2016
    Inventor: Rajdeep S. Pavaskar
  • Nanoscale platinum compounds and methods of use thereof
    Patent number: 9393227
    Abstract: The invention is directed to biocompatible conjugated polymer nanoparticles including a copolymer backbone, a plurality of sidechains covalently linked to said backbone, and a plurality of platinum compounds dissociably linked to said backbone. The invention is also directed to dicarbonyl-lipid compounds wherein a platinum compound is dissociably linked to the dicarbonyl compound. The invention is also directed to methods of treating cancer or metastasis. The methods includes selecting a subject in need of treatment for cancer or metastasis and administering to the subject an effective amount of any of the nanoparticles, compounds, or compositions of the invention.
    Type: Grant
    Filed: February 4, 2010
    Date of Patent: July 19, 2016
    Assignee: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventors: Shiladitya Sengupta, Abhimanyu Paraskar, Shivani Soni, Sudipta Basu, Poulomi Sengupta
  • High drug load buprenorphine microspheres and method of producing same
    Patent number: 9393211
    Abstract: A sustained release microsphere formulation with a high drug load may be formed by a continuous oil-in-water emulsion process by combining an organic dispersed phase with an aqueous continuous phase. The dispersed phase may include an encapsulating polymer, a primary solvent, such as dichloromethane, a pharmaceutically effective amount of an active agent having a solubility relative to the dispersed phase, and a co-solvent, such as benzyl alcohol, which is capable of increasing the solubility of the active agent relative to the dispersed phase. The continuous phase may include an aqueous solution of polyvinyl alcohol and water.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: July 19, 2016
    Assignee: Oakwood Laboratories LLC
    Inventors: Tracy Richey, Bagavathikanun Chithambara Thanoo
  • Chitosan derivatives for inactivation of endotoxins and surface protection of nanoparticles
    Patent number: 9393262
    Abstract: The present disclosure provides a polymer comprising a derivative of chitosan, wherein the derivative is zwitterionic, as well as methods of using the polymer. In addition, the present disclosure provides a nanoparticle structure comprising a derivative of chitosan and a dendrimer, as well as methods of utilizing the nanoparticle structure.
    Type: Grant
    Filed: September 27, 2012
    Date of Patent: July 19, 2016
    Assignee: PURDUE RESEARCH FOUNDATION
    Inventors: Yoon Yeo, Gaurav Bajaj, Peisheng Xu, Karen Liu, Eun Jung Cho
  • Process of preparing a crosslinked gel
    Patent number: 9393189
    Abstract: The subject of the present invention is a process of preparing a crosslinked gel of at least one polysaccharide or one of its salts, including at least the steps consisting in: a) providing, at a temperature below 35° C., an aqueous gel including at least one polysaccharide in an uncrosslinked form together with at least one difunctional or multifunctional epoxy crosslinking agent; b) maintaining the mixture of step a) at a temperature below 35° C. for at least one hour; c) stimulating the crosslinking reaction of the mixture obtained after step b), and if need be; d) recovering said crosslinked gel formed.
    Type: Grant
    Filed: December 6, 2011
    Date of Patent: July 19, 2016
    Assignee: TEOXANE
    Inventors: Stephane Meunier, Francois Bourdon
  • Direct inkjet fabrication of drug delivery devices
    Patent number: 9381154
    Abstract: In some aspects of the present application, a method of forming one or more layers of at least a portion of a drug delivery device (DDD) is described. The method can include providing a substrate; providing one or more DDD components that are dissolved or dispersed in one or more pharmaceutically compatible phase change inks; ejecting, by one or more nozzles, a first portion of the one or more pharmaceutically compatible phase change inks to form a first layer on the substrate; and ejecting, by the one or more nozzles, a second portion of the pharmaceutically compatible phase change inks to form a second layer over the first layer.
    Type: Grant
    Filed: June 9, 2011
    Date of Patent: July 5, 2016
    Assignee: Xerox Corporation
    Inventors: Jing Zhou, Shu Chang
  • Micro-particles, blood-substitute and method for forming same
    Patent number: 9381162
    Abstract: A method for forming micro-particles is provided. The method includes the steps of: —providing a first solution which includes at least an anion; —providing a second solution which includes at least a cation; —mixing the first solution with the second solution in presence of at least a first compound for forming porous templates, wherein the porous templates are formed by precipitation of a salt which includes the anion and the cation and wherein the first compound is at least partially incorporated in the porous templates; and—at least partially cross-linking the first compound in the porous templates.
    Type: Grant
    Filed: July 14, 2008
    Date of Patent: July 5, 2016
    Assignee: CC-Ery GmbH
    Inventors: Hans Bäumler, Radostina Georgieva