Abstract: The present invention relates to a method to prevent a premature LH surge. The method employs the administration of the gonadotropin releasing hormone antagonist ganirelix in an amount between 0.125-1 mg in combination with exogenous FSH. The method can be used in the treatment of women undergoing controlled ovarian superovulation.
Type:
Grant
Filed:
December 20, 1999
Date of Patent:
November 25, 2003
Assignee:
Akzo Nobel NV
Inventors:
Bernadette Maria Julia Louise Mannaerts, Herman Jan Tijmen Coelingh Bennink, Everardus Otto Maria Orlemans