Abstract: Image guided surgery includes capturing a primary modality image of a surgical field of a patient with a camera system, obtaining a secondary modality image of the surgical field registered to the primary image, generating a surgical guidance image based at least in part upon the secondary modality image, and projecting the surgical guidance image onto the patient. The surgical guidance image presents visual augmentations on or over the patient to inform a medical practitioner during a surgical procedure.

Abstract: An ultrasonic diagnostic imaging system acquires different kinds of pilot images showing different characteristics of a region of a body where shearwave measurements are performed. The pilot images are analyzed by a push pulse locator to adaptively generate push pulses at locations in the body which minimize or avoid shearwave travel through blood vessels, through regions of stiffness inhomogeneities in the body, or at times when shearwaves are adversely affected by tissue motion.

Abstract: A system and method for controlling the delivery of ultrasound energy to a subject is provided. In particular, such a system and method are capable of safely disrupting the blood-brain barrier. Ultrasound energy is delivered to produce cavitation of an ultrasound contrast agent at a selected pressure value. An acoustic signal is acquired following cavitation, from which a signal spectrum is produced. The signal spectrum is analyzed for the presence of harmonics, such as subharmonics or ultraharmonics. When subharmonics or ultraharmonics are present, the pressure value is decreased for subsequent sonications. If a previous sonication resulted in no subharmonics or ultraharmonics being generated, then the pressure value may be increased. In this manner, the blood-brain barrier can be advantageously disrupted while mitigating potentially injurious effects of the sonication.

Abstract: To correctly trace a target component even when a folded component is included in a Doppler waveform. The Doppler waveform is configured by a plurality of luminance distributions 54 arranged on a time axis. In each luminance distribution 54, a minimum luminance value located in the trough portion 54c between the target portion 54a and the folded portion 54b is specified. A search start point Pn is set based on the minimum luminance value. A trace point 60 is specified by searching from the search start point Pn to a base line 61 side.

Abstract: A surgical instrument navigation system is provided that visually simulates a virtual volumetric scene of a body cavity of a patient from a point of view of a surgical instrument residing in the cavity of the patient. The surgical instrument navigation system includes: a surgical instrument; an imaging device which is operable to capture scan data representative of an internal region of interest within a given patient; a tracking subsystem that employs electro-magnetic sensing to capture in real-time position data indicative of the position of the surgical instrument; a data processor which is operable to render a volumetric perspective image of the internal region of interest from a point of view of the surgical instrument; and a display which is operable to display the volumetric perspective image of the patient.

Abstract: Two or more learning images generated for a first subject or a second subject and one or more correct answer images generated for the second subject or a third subject are received. In a case where pixel values of corresponding pixels of the two or more learning images are synthesized by using a synthesis parameter value, the parameter value at which the synthesized pixel values are close to a pixel value of a corresponding pixel of the correct answer image is obtained. An image generated for the first subject and having the same type as the two or more learning images is received as an examination target image. A synthesized image desired by a user is generated by synthesizing pixel values of corresponding pixels of the two or more examination target images by using the synthesis parameter value.

Abstract: Methods and apparatus are configures to measure an eye without contacting the eye with a patient interface, and these measurements are used to determine alignment and placement of the incisions when the patient interface contacts the eye. The pre-contact locations of one or more structures of the eye can be used to determine corresponding post-contact locations of the one or more optical structures of the eye when the patient interface has contacted the eye, such that the laser incisions are placed at locations that promote normal vision of the eye. The incisions are positioned in relation to the pre-contact optical structures of the eye, such as an astigmatic treatment axis, nodal points of the eye, and visual axis of the eye.

Abstract: An ultrasound imaging apparatus includes: a probe configured to transmit ultrasound waves and detect echo signals; a display; and at least one processor configured to generate an ultrasound image based on the echo signals, wherein the at least one processor is further configured to obtain a three-dimensional (3D) medical image of a uterus, determine a target position for embryo transfer based on the 3D medical image, obtain a real-time ultrasound image of the uterus, identify the target position in the real-time ultrasound image, and control the display to display the real-time ultrasound image and information about the target position.

Abstract: High-quality magnetic resonance (MR) recordings are triggered with movements of an object, for example the heartbeat. In a method and apparatus for obtaining raw data reconstruction for an MR image, a spin-echo-based sequence is executed that includes applying a static magnetic field and applying a magnetization pulse train. A movement of the object to be imaged is detected and a target contrast for two tissue types of the object is prespecified. The repetition time of the pulse train is set in dependence on the movement of the object to be imaged, and the flip angle is set such that prespecified target contrast for the two tissue types is obtained at the set repetition time.

Abstract: A surgical instrument navigation system is provided that visually simulates a virtual volumetric scene of a body cavity of a patient from a point of view of a surgical instrument residing in the cavity of the patient, wherein the surgical instrument, as provided, may be a steerable surgical catheter with a biopsy device and/or a surgical catheter with a side-exiting medical instrument, among others. Additionally, systems, methods and devices are provided for forming a respiratory-gated point cloud of a patient's respiratory system and for placing a localization element in an organ of a patient.

Abstract: A method for providing artifact detection and visualization during ultrasound image collection is performed by a processor in an ultrasound system. The method includes receiving ultrasound image data from an ultrasound probe, detecting areas with artifacts in the ultrasound image data, classifying the areas with artifacts into one of a plurality of available artifact classes, generating an indication of the areas with artifact for an ultrasound-based image, wherein the indications include a designation of the artifact class, and presenting to an operator the ultrasound-based image and the indication of the areas with artifacts.

Abstract: A method includes receiving ultrasound echo signals produced in response to a pulsed ultrasound field interacting with anatomical tissue and flow of structure therein. The method further includes generating electrical signals indicative thereof. The method further includes beamforming the electrical signals producing beamformed data. The method further includes constructing a real-time image of the anatomical tissue with the beamformed data. The method further includes constructing a de-aliased color images of the flow with the beamformed data. The method further includes visually presenting the real-time image of the anatomical tissue with the de-aliased color images of the flow superimposed thereover.

Abstract: An apparatus can be used to generate acoustic imaging pulse sequences and receive corresponding echoes elicited by the acoustic imaging pulse sequences. An acoustic radiation force (ARF) pulse sequence can be generated to agitate a contrast medium in a tissue region between the acoustic imaging pulse sequences. A decorrelation between images corresponding to the received echoes can be determined. A weighting map can be applied to an image to weight a region of the image corresponding to a spatial location of the contrast medium using the determined decorrelation. In an example, the receiving of corresponding echoes elicited by the acoustic imaging pulse sequences can include receiving acoustic energy having a range of frequencies offset from a fundamental frequency associated with the acoustic imaging pulse sequences. An acoustic imaging pulse sequence can include a pulse having an inverted amplitude envelope with respect to another pulse included in the sequence.

Abstract: A digital topographic model of the luminal surface is generated by projecting an optical pattern on the luminal surface from the first location within the lumen. At least a portion of the projected pattern is detected from a second location within the lumen which is based apart from the first location. The dimensions of the luminal wall can be measured by triangulation in order to produce the digital topographic model of the body lumen.

Abstract: An imaging system (100) includes a subject support (114) that supports a subject in an examination region (106). The imaging system further includes a detector (112) that detects a signal traversing the examination region, generating an output indicative of the examination region. The imaging system further includes a subject motion sensing system (118) that includes an optical system (206, 208, 214) that detects motion of the subject in the examination region and generates motion data indicative thereof. The imaging system further includes a console (122) that controls at least one of data acquisition or reconstruction based on the motion data.

Abstract: Methods and systems of optically measuring systolic and/or diastolic blood pressure of a mammal having biological tissue are disclosed herein. In some embodiments, the system comprises an optical blood motion sensor, a gas-sealable inflatable cushion having a flexible and transparent (FOT) barrier section, and an optical blood motion sensor comprising a laser. When pressure (e.g. at least systolic pressure) illuminates the tissue, laser light may pass en route to the tissue through the FOT sealing barrier section of the gas-sealable inflatable cushion as well as cushion interior. In some embodiments, a rigid restrictor comprising an optically transparent section is provided, and laser light also passes through the optically transparent section of the rigid restrictor en route to the biological tissue.

Abstract: The invention features methods for detecting the hydration state or vascular volume of a subject using a device capable of nuclear magnetic resonance (NMR) measurement. The methods involve exposing a portion of a tissue of the subject in vivo to a magnetic field and RF pulse from the device to excite hydrogen nuclei of water within the tissue portion, and measuring a relaxation parameter of the hydrogen nuclei in the tissue portion, the relaxation parameter being a quantitative measure of the hydration state or vascular volume of the subject as a whole. The invention also features devices and computer-readable storage media for performing the methods of the invention.

Abstract: An ultrasound image processing apparatus (200) is disclosed for obtaining a biometric measurement of an anatomical feature of interest from a 3D ultrasound image.

Abstract: A method is for the characterization of plaque in a region of interest inside an examination subject by way of a plurality of image data sets. The image data sets have been reconstructed from a plurality of projection data sets, which have been acquired via a CT device using different X-ray energy spectra. The method includes: acquiring the image data sets, which include a plurality of pixels. Spectral parameter values are acquired on a pixel by pixel basis using at least two image data sets. Character parameter values are then acquired on a pixel by pixel basis to characterize plaques on the basis of the spectral parameter values. An analysis unit and a computed tomography system are also disclosed.

Abstract: A method to increase the reliability and clinical utility of diffusion tensor imaging (DTI) of traumatic brain injury (TBI) in single subjects and a semi-automated method of identifying and quantifying small hemorrhages using susceptibility-weighted images (SWI) of single subjects include storing an image template formed from control subjects, storing a brain image of the single subject, correcting for image acquisition differences of the control subjects and single subject, and performing regional analysis of the brain image of the single subject. The method may include analysis of fractional anisotropy values that are age-corrected between the control subjects and the single subject before performing voxel-based analysis (VBA), and a hybrid VBA and tract-based spatial statistical (TBSS) analysis with the VBA and TBSS results combined using a statistical calculation. The resulting combined DTI image may be further combined with an SWI image, FLAIR image, and/or T1 image of the single subject.