Patents Examined by Bo Pneg
  • Metabolically activated recombinant viral vectors and methods for their preparation and use
    Patent number: 8093054
    Abstract: Recombinant viral vectors, especially parvovirus vectors such as adeno-associated virus (AAV) vectors; capable of enhanced expression of heterologous sequences, and methods for their construction and use, are provided. The vectors have a structure, or are capable of rapidly adopting a structure, which involves intrastrand base pairing of at least one region in a heterologous sequence.
    Type: Grant
    Filed: October 22, 2010
    Date of Patent: January 10, 2012
    Assignee: Genzyme Corporation
    Inventor: Barrie J. Carter