Patents Examined by Brad Gordon
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Patent number: 10953367Abstract: The present invention relates to a method of concentrating an aqueous solution by low pressure under a zero osmotic pressure difference condition, and more particularly to a method of concentrating a solute-containing aqueous solution by low pressure under a zero osmotic pressure difference condition. When the method of the present invention is used, there are advantages in that energy consumption is low, and an aqueous solution can be concentrated until it can reach the maximum solute concentration or a solute concentration of 100%, without having to use an extraction solvent. In addition, there is an advantage in that the need to use a separate osmotic pressure draw solution is eliminated.Type: GrantFiled: July 25, 2016Date of Patent: March 23, 2021Assignee: LAB TO MARKET INC.Inventor: Ho Nam Chang
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Patent number: 10946343Abstract: The present disclosure relates to improved semipermeable membranes based on acrylonitrile copolymers for use in dialyzers for the extracorporeal treatment of blood in conjunction with hemodialysis, hemofiltration or hemodiafiltration. The present disclosure further relates to methods of producing such membranes.Type: GrantFiled: July 28, 2016Date of Patent: March 16, 2021Assignee: GAMBRO LUNDIA ABInventor: Benjamin Malard
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Patent number: 10946345Abstract: Hydrophobic hollow-fiber membrane made from a vinylidene fluoride polymer with a wall and a wall thickness, an outer surface on its outer side, an inner surface on its inner side and facing its lumen and adjacent to the inner surface a supporting layer having a structure that is substantially isotropic across the wall thickness, the supporting layer extending over at least 80% of the wall thickness and comprising pores having an average diameter of less than 1 ?m, and wherein the hollow-fiber membrane has pores on its outer surface and on its inner surface, characterized in that the vinylidene fluoride polymer has a weight-average molecular weight MW in the range from 550 000 to 700 000 daltons and a polydispersivity greater than 3.0; the pores in the outer and in the inner surface are formed like islands and have a maximum ratio of their longitudinal extension to the transverse extension of 10; the porosity lies in the range from 50 to 90 vol.Type: GrantFiled: May 22, 2014Date of Patent: March 16, 2021Assignee: EM Innovative Properties CompanyInventors: Oliver Schuster, Quan Huang, Ngoc-Phung Duong, Karl Bauer, Wolfgang Ansorge
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Patent number: 10940254Abstract: The invention relates to an apparatus for extracorporeal blood treatment that comprises a device 1 for providing fresh dialysate and a drain 2 for used dialysate, a balancing device 4 for balancing fresh dialysate and used dialysate, an ultrafiltration device 15, and a dialyser 3 that is divided into a blood chamber 6 and a dialysate chamber 7 by a semi-permeable membrane 5. The invention further relates to a method for operating such an apparatus for extracorporeal blood treatment. The apparatus according to the invention is based on the use of the ultrafiltration device 15 of the blood treatment apparatus for raising the liquid level in the air separation device 12 on the secondary side of the dialysate system I. In the apparatus according to the invention, the ultrafiltration device 15 is designed such that the ultrafiltration device can be operated not only in an ultrafiltration mode, but also in a ventilation mode.Type: GrantFiled: January 4, 2017Date of Patent: March 9, 2021Assignee: Fresenius Medical Care Deutschland GmbHInventor: Jurgen Hacker
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Patent number: 10918999Abstract: In a cell-capturing filter including a metal porous membrane, degradation over time is determined earlier. A cell-capturing filter includes a metal porous membrane having a plurality of through-holes that penetrate between two principal surfaces facing each other. The metal porous membrane is made of an alloy of nickel and an element selected from the group consisting of gold, platinum, and palladium, or a metal containing nickel as a main component. A metal containing copper as a main component is attached to a part of either one of the principal surfaces of the metal porous membrane. By checking a state change of the metal containing copper as a main component, degradation over time of the metal porous membrane can be determined earlier.Type: GrantFiled: October 31, 2018Date of Patent: February 16, 2021Assignee: MURATA MANUFACTURING CO., LTD.Inventors: Masaru Banju, Wataru Yamamoto, Junko Watanabe, Takashi Kondo
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Patent number: 10912877Abstract: The present invention relates to an apparatus for the extracorporeal removal of protein-bound toxins from blood comprising at least one blood purification apparatus, in particular at least one dialysis machine, hemofilter or adsorber, as well as at least one means for generating a field in the blood purification apparatus and/or in an element in flow communication with the blood purification apparatus, in particular in a line section connected to the blood purification apparatus, wherein the means comprises at least two strip conductors which are arranged on at least two preferably oppositely disposed sides of the blood purification apparatus or of the element such that the field is preferably predominantly generated within the blood purification apparatus or preferably predominantly within the element.Type: GrantFiled: July 20, 2015Date of Patent: February 9, 2021Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBHInventors: Anselm Fabig, Ulrich Tschulena, Sonja Steppan
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Patent number: 10898865Abstract: This invention relates to an asymmetric composite membrane containing a polymeric matrix and carbon nanotubes within a single membrane layer, where the carbon nanotubes are randomly oriented within the polymeric matrix and the composite membrane is formed by phase inversion. This invention also relates to a method for producing the composite membrane which includes: coating a surface with a film of a polymer solution containing a polymeric matrix and carbon nanotubes dissolved in at least one solvent; immersing the coated surface in a non-solvent to affect solvent/non-solvent demixing resulting in phase inversion to form a carbon nanotube-containing membrane; and optionally, removing the carbon nanotube-containing membrane from the surface. The invention also relates to a desalination method using the composite membrane.Type: GrantFiled: January 31, 2013Date of Patent: January 26, 2021Assignee: AMERICAN UNIVERSITY IN CAIRO (AUC)Inventors: Nouran Ashraf Abdel Hamied El Badawi, Amal Mohamed Kamal Esawi, Adham Ramzy Ramadan
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Patent number: 10898861Abstract: Disclosed are methods of preparing antifouling coatings on reverse osmosis membranes with initiated vapor deposition or oxidative vapor deposition. The coatings enhance the stability and lifetime of membranes without sacrificing performance characteristics, such as permeability or salt retention.Type: GrantFiled: July 20, 2018Date of Patent: January 26, 2021Assignee: Massachusetts Institute of TechnologyInventors: Minghui Wang, Karen K. Gleason, Peter Kovacik
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Patent number: 10898862Abstract: This repair method for a hollow fiber membrane module is a method for repairing a leaking section occurring in the hollow fiber membrane module, the repair method having a repair step for using a repair adhesive that hardens due to a composite curing function that comprises a moisture-curing function and a photo-curing function, to repair the leaking section.Type: GrantFiled: June 15, 2012Date of Patent: January 26, 2021Assignee: Mitsubishi Chemical CorporationInventors: Noritaka Shibata, Takashi Hinenoya, Takahiro Mori, Toshinori Tanaka
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Patent number: 10888822Abstract: The present invention provides a separation membrane having excellent separation performance and permeation performance, having high membrane strength, and mainly including a cellulose-based resin. The present invention relates to a separation membrane containing a cellulose ester and having a tensile elasticity of 1,500 to 6,500 MPa.Type: GrantFiled: September 30, 2015Date of Patent: January 12, 2021Assignee: Toray Industries, Inc.Inventors: Gohei Yamamura, Koichi Takada, Ryuichiro Hiranabe, Hiroki Tomioka
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Patent number: 10889796Abstract: A metallic porous membrane that classifies cell aggregates includes a membrane section having a first principal surface for capturing the cell aggregates, a second principal surface opposing the first principal surface, and a plurality of through-holes communicating with the first principal surface and the second principal surface.Type: GrantFiled: August 28, 2018Date of Patent: January 12, 2021Assignee: MURATA MANUFACTURING CO., LTD.Inventors: Takashi Kondo, Masaru Banju, Junko Watanabe, Makoto Hasegawa, Tamio Mizukami
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Patent number: 10870083Abstract: A polyvinylidene fluoride (PVDF) casting membrane solution is shaped as a flat sheet membrane by thermally induced phase separation (TIPS), the PVDF membrane is defluorinated with an alkaline potassium permanganate solution, and then the carbon chain is extended with glycidyl methacrylate (GMA) as the graft monomer, and finally the nucleophilic substitution is carried out between melamine and GMA to produce a chelating microfiltration membrane for capturing and enriching heavy metals with high flux and high capacity.Type: GrantFiled: June 15, 2017Date of Patent: December 22, 2020Assignee: NANJING UNIVERSITYInventors: Fuqiang Liu, Yanhong Zhang, Li Song, Wei Zhao, Changqing Zhu, Chen Ling, Aimin Li
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Patent number: 10870607Abstract: An inorganic membrane filtration article and methods for making the same. The membrane filtration article includes a sintered flow-through ceramic honeycomb with a plurality of partition walls defining a plurality of open channels from an inlet end of the honeycomb to an outlet end of the honeycomb. The honeycomb is formed from a cordierite composition with low-sodium and/or low-potassium content for enhanced filtration performance.Type: GrantFiled: October 27, 2016Date of Patent: December 22, 2020Assignee: Corning IncorporatedInventors: Curtis Robert Fekety, Yunfeng Gu, Yanxia Ann Lu, Zhen Song
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Patent number: 10857277Abstract: Apparatuses, systems, and methods for the performance of kidney replacement therapy having or using a dialyzer, control components, sorbent cartridge, and fluid reservoirs configured to be of a weight and size suitable to be worn or carried by an individual requiring treatment are disclosed. The system has a controlled compliance dialysis circuit, where a control pump controls the bi-directional movement of fluid across a dialysis membrane. A first sorbent cartridge is provided for use in a portable treatment module having activated carbon and zirconium oxide. The system also provides for the monitoring of an inlet and outlet conductivity of a sorbent cartridge containing urease to provide a facility to quantify or monitor the removal of urea by a detachable urea removal module.Type: GrantFiled: August 15, 2012Date of Patent: December 8, 2020Assignee: Medtronic, Inc.Inventors: Thomas D. Kelly, SuPing Lyu, Bryant J. Pudil, Thomas E. Meyer
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Patent number: 10858624Abstract: A filter for filtering nucleated cells that includes a body containing at least either a metal or a metal oxide as its main component; and plural through holes, each of which have a shape other than a square shape, formed therein. A longitudinal diameter of an inscribed ellipse within each of the through holes is smaller than a size of a nucleus of each of the nucleated cells to be filtered. The inscribed ellipse of the through hole is an ellipse that abuts all sides that define an opening of the through hole.Type: GrantFiled: February 26, 2018Date of Patent: December 8, 2020Assignee: MURATA MANUFACTURING CO., LTD.Inventors: Masaru Banju, Junko Watanabe, Takashi Kondo, Seiichi Matsumoto
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Patent number: 10858623Abstract: Compositions and methods are provided for removing viral contaminants from a chemically defined cell culture medium. Compositions provided herein are resistant to or exhibit reduced fouling by one or more components in a chemically defined cell culture medium.Type: GrantFiled: September 30, 2015Date of Patent: December 8, 2020Assignee: EMD Millipore CorporationInventors: Antoni Peters, Philip M. Goddard
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Patent number: 10851241Abstract: Multicomponent copolymers including two or more types of repeat units is presented. In one example, the multicomponent copolymer includes at least one repeat unit AC having a structure (I), at least one repeat unit DC having a structure (II), and at least one repeat unit BC having a structure (III) or (V). The multicomponent copolymer may be cross-linked via a cross-linking agent. A polymer blend including the multicomponent copolymer or a cross-linked copolymer and a second polymer is also provided. The multicomponent copolymer may be a random or a block copolymer. The structural units of the multicomponent copolymers provide improved, tunable properties, such as improved biocompatibility and hydrophilicity, protein fouling, and mechanical properties, to the copolymers and/or the membranes fabricated from the copolymers.Type: GrantFiled: May 15, 2018Date of Patent: December 1, 2020Assignee: Cytiva Sweden ABInventors: David Moore, Matthew Jeremiah Misner, Hongyi Zhou, Patrick McCloskey, Matthew Rainka
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Patent number: 10835665Abstract: A manually openable clamping holder for releasably fixing a single-use medical device to a medical treatment apparatus has a sensor for detecting the position of the clamping jaws of the clamping holder. With the clamping holder, the correct equipping of a medical treatment apparatus with the appropriate single-use device can be monitored economically and with simple operation.Type: GrantFiled: November 8, 2011Date of Patent: November 17, 2020Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBHInventor: Nicolas Beisser
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Patent number: 10752526Abstract: A method of decreasing the concentration of certain contaminants in liquids by the chemical reduction of the contaminant using a hydride. A suitable reactor is charged with the contaminated liquid. An amount of catalyst and then an amount of hydride are added to the reactor. The hydride reacts with the contaminant in the liquid, chemically reducing and thus destroying a portion of the contaminant and thereby reducing the concentration of the contaminant in the liquid. Additional hydride can be added to further reduce the concentration to meet a desired level.Type: GrantFiled: March 15, 2013Date of Patent: August 25, 2020Assignee: Bluflow Technologies, Inc.Inventors: William A. Farone, Shane L. Palmer, Miguel A. Rivera, Christian Taylor, Dwayne Chong
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Patent number: 10737011Abstract: An apparatus for extracorporeal treatment of blood including a filtration unit, a blood withdrawal line, a blood return line, an effluent fluid line, a dilution fluid line connected to the blood withdrawal line, and a dialysis fluid line. Pumps act on the fluid lines for regulating the flow of fluid. A control unit sets initial values for a fluid flow rate(s) through the lines and periodically executes a flow rate update procedure to adjust the fluid flow rate(s) to deliver a set dose (Dset) in a reference time interval.Type: GrantFiled: September 8, 2011Date of Patent: August 11, 2020Assignee: GAMBRO LUNDIA ABInventor: Dominique Pouchoulin