Abstract: An intravenous (IV) coupling apparatus is disclosed for fluid delivery to a patient. The coupling includes a tube having an input end and an output end, wherein the input end includes a plurality of input connections configured to releasably couple to one or more input lines in communication with one or more fluid sources, and the output end includes a plurality of output connections configured to releasably couple to one or more output lines configured to deliver fluid to the patient. The coupling includes a plurality of lumens disposed within the tube substantially along the length of the tube, wherein each lumen couples one of the input connectors in fluid communication with a corresponding output connector such that an input line is in fluid communication with a corresponding output line when the input line and output line are connected to a corresponding input connector and output connector.

Abstract: The present invention provides a puncture needle set for combined spinal-epidural anesthesia comprising an epidural needle with a small guiding conduit on the pin and a groove on the outer wall and a spinal needle with a beaked tip. During anesthesia, first the epidural needle is punctured into the epidural space, then the epidural catheter is placed, afterwards the spinal needle is guided to enter into the groove on the needle peduncle by the small conduit on the pin of the epidural needle and slide into the epidural space, then let it go ahead deep into subarachnoid space. After medicine is injected, the spinal needle and the epidural needle are withdrawn in turn, at the same time the epidural catheter is left back.

Abstract: A limb wound treatment device is described having a first end, a second end and an interior therebetween for accommodating a treatment gas. The device can include a flexible housing that can be inflated. The first end can include an inflatable cuff seal for hermetically sealing against the limb being treated. The second end can include a closed end or an access port that is releasably sealed with a clamping mechanism. Further, the device can include a controller that can inflate that housing, inflate the cuff seal and provide treatment gas to the interior, in response to pressures within the cuff seal and the housing. Further, the device can accommodate different types of wound treatments, such as hyperbaric therapy, compression therapy or negative pressure therapy.

Abstract: This disclosure relates to drug delivery devices, systems, and methods. In some aspects, a drug delivery device includes an elongate member defining a fluid passage and an opening in fluid communication with the fluid passage, and a projection extending radially from the elongate member. A portion of the elongate member extending axially from the projection to a distal end of the elongate member has a length sufficient to allow the distal end of the elongate member to reach subdermal tissue of a patient when the elongate member is inserted into the patient and the projection is in contact with an outer surface of skin of the patient, and the opening is positioned at a location along the elongate member such that the opening is disposed within a dermis of the patient when the elongate member is inserted into the patient and the projection is in contact with the outer surface of the skin of the patient.

Abstract: A method and system for limiting a maximum dose that may be set in a drug delivery device. A dose setting mechanism, which is operable to be coupled to a medication cartridge, comprises a lock-out mechanism that prevents one from setting a dose greater than the medication in the cartridge. The lock-out mechanism comprises a rotatable shaft. A helical groove having a first pitch is provided along a first portion of the rotatable shaft and a second pitch provided along a second portion of the rotatable shaft. The first pitch is different from the second pitch. A third pitch may be provided on a third portion of the shaft. This third pitch is provided at the end of the second pitch and is preferably different than the second pitch. The lock-out mechanism further comprises a non-rotating member disposed on the helical groove of said shaft.

Abstract: Methods and devices for administration of substances into at least two compartments of skin for systemic absorption and improved pharmacokinetics, based on biphasic or bimodel kinetic profiling.

Abstract: An electrosurgical instrument for cutting tissue includes a blade assembly. The blade assembly includes a first electrode having a first pre-selected shape and a first distal edge, and a second electrode disposed in spaced relation relative to the first electrode. The second electrode includes a second pre-selected shape and a second distal edge, where the first distal edge and the second distal edge form an electrically conductive tissue cutting surface extending along the distal end of the instrument. The tissue cutting surface is adapted to connect to a source of electrosurgical energy such that the tissue cutting surface is capable of conducting electrosurgical energy through tissue adjacent thereto to effectively cut tissue.

Abstract: The technology disclosed herein pertains to wound healing electrodes and devices. The technology disclosed herein also pertains to electrode sets for electrically induced wound healing that can be adjusted to the wound size.

Abstract: Assemblies and methods of inserting a delivery catheter assembly into a working channel are disclosed. In accordance with some embodiments, a delivery catheter assembly is disclosed in which a tip protector sleeve is locked onto an elongated catheter sheath and slideable over a length of the elongated catheter sheath between a proximal-stop position and a distal-stop position along the elongated catheter sheath.

Abstract: An assistive device that couples a syringe and medicine bottle primarily for use by diabetics as a means of securing the syringe when sliding the bottle up to meet the syringe tip in order to fill the syringe with insulin, and then slide the bottle back out. The insulin may then be given as a shot to a patient.

Abstract: An infusion assembly is provided having a first outlet conduit adapted to be in fluid communication with a delivery site of a patient. The assembly further includes at least first and second fluid inlet conduits adapted to be in fluid communication with at least a first and second fluid reservoir, and an infusion switching device, including a housing and an internal valve assembly. The internal valve assembly is adapted for selective manipulation by a patient or caregiver. The valve assembly includes an off-setting, and first infusion setting, for initiating an infusion of a first fluid from a first fluid reservoir to a delivery site, and a second infusion setting for initiating an infusion of a second fluid from a second fluid reservoir to a delivery site.

Abstract: A housing component of a drug delivery device to accommodate a drive mechanism, wherein the drive mechanism is operable to interact with a piston of a cartridge containing a medicinal product to be dispensed by the drug delivery device. The housing component comprises at least one radially inwardly extending flange portion to be operably engaged with a piston rod of the drive mechanism, wherein that the flange portion is at least partially structurally strengthened.

Abstract: Some embodiments an infusion pump system can be used to determine a user's total insulin load (TIL) that provides an accurate indication of the insulin previously delivered to the user's body which has not yet acted. In particular embodiments, the TIL can account for both the bolus deliveries and the basal deliveries that have occurred over a period of time. Such information may be useful, for example, when the infusion pump is operated in conjunction with a continuous glucose monitoring device.

Abstract: Peristaltic pump assemblies in which the closing and opening of a pivoting or sliding door is coordinated with movement of the occlusion bed toward and away from the rotor assembly to engage and disengage tubing within the occlusion pathway are disclosed. Linkage mechanisms provided by the interaction of cam surfaces with rollers, as well as bar linkage mechanisms, are disclosed. The linkage mechanism, in addition to providing precise displacement of the occlusion bed, may also provide an over-center feature that enhances safety and pump operation when the door is in a closed position. Latching mechanisms and sensors may be incorporated. Control consoles incorporating such peristaltic pump assemblies are described. Adaptive components such as tubing cassettes routing aspiration and/or infusion tubing in a predetermined configuration to mate with occlusion pathways in aspiration and/or infusion pump assemblies provided in various types of medical devices and control consoles are also provided.

Abstract: The invention provides a system and method for percutaneous energy delivery in an effective, manner using one or more probes. Additional variations of the system include array of probes configured to minimize the energy required to produce the desired effect.

Abstract: A securement device (10) secures a medical article (12) to the body of a patient and prevents longitudinal movement of the medical article (12) relative to the securement device (10). The securement device (10) includes a base portion (50) that is disposed over at least a part of a securement piece (20). The securement piece (20) forms a channel (19) configured to receive at least a portion of the medical article (12). The device (10) includes at least one actuator (40). The at least one actuator (40) is coupled with the securement piece (20) and configured to move the securement piece (20) between open position and a closed position. When the securement piece (20) is in the open position, it can receive at least a portion of the medical article (12). When the securement piece (20) is in the closed position, it prevents the received medical article (12) from moving in the longitudinal direction relative to the securement device (10).

Abstract: A steerable multi-polar lead shaft assembly includes a core member extending longitudinally through the shaft assembly, a plurality electrically conductive elements disposed within the core member, a plurality of steering wires circumferentially distributed about the core member. A control mechanism for a steerable catheter, such as the steerable multi-polar lead assembly, includes a mounting portion adapted to engage a steerable shaft, a stem extending from the mounting portion, a swivel joint arranged at a proximal end of the stem, a control yoke rotatably mounted on the swivel joint, adapted to engage a plurality of steering wires of the steerable catheter, and a handle connected with the yoke, adapted for direct manipulation by a user.

Abstract: A universal device for securing a catheter on a patient includes a base which optionally has one or more locating elements for positioning or securing a catheter or catheter fitting of various shapes or sizes. The base optionally includes a recessed or flat receiving area defined by locating elements arranged to hold or receive a catheter or catheter fitting. Additional locating elements may be positioned elsewhere for receiving or holding a flange or wing of a catheter fitting. A cover is removably or permanently connected to the base and may optionally have one or more top openings for receiving tabs or extensions of a catheter fitting. The cover may optionally include one or more capture ridges for restraining a catheter or catheter fitting of various shapes or sizes on the base or on the retention plate. The cover may also include one or more tabs or contact bars.

Abstract: A medical fluid or dialysis system includes an auto-connection mechanism that connects connectors from the supply bags to dialysis cassette ports or cassette supply lines. The system provides for multiple, e.g., four, supply bags, which can be connected to a manifold of the auto-connection mechanism. Tip protecting caps that protect the supply line ends and cassette ports or cassette supply line ends are made to be compatible with the auto-connection mechanism. The auto-connection mechanism removes all the caps and connects the supply lines to the cassette. At least one roller occluder is provided that occludes the supply tubing prior to the tip protecting caps being removed. The roller occludes prevent medical dialysis fluid from spilling out of the supply lines between the time that the caps are removed and connection to the cassette is made.

Abstract: A device and method for safely securing a multilumen device to a tissue, organ or solid tumor within the body of a human during a diagnostic or therapeutic procedure is described. The device is capable of securing the tumor by touching or piercing its surface and providing a coolant to the distal tip. Cooling the tip forms a cryogenically induced region that tightly binds the tip to the tumor, temporarily sealing the entry-track of the instrument. The device further provides at least one injecting/aspirating lumen that can dispense or aspirate a fluid within the tumor, and an outer sheath or guide. Such construction allows injecting part or whole volume of the tumor while the cryogenically induced bond prevents back-flow of the injected substances through the entry-track.