Patents Examined by Bradley R Spies
  • Patent number: 12246305
    Abstract: Aspects of the present disclosure relate to a method of regenerating a hydrophobic interaction chromatography column to which a load mass has been applied, the method comprising passing one or more column volumes of an alkaline solution through hydrophobic interaction media within the column, wherein the alkaline solution exhibits a pH of between about 10 and about 14, and a conductivity of between 0.5 mS/cm and about 10 mS/cm, wherein material bound to the hydrophobic interaction media is removed. In some cases, the alkaline solution may include sodium hydroxide at a concentration of between, e.g., about 0.1 mM and 10 mM.
    Type: Grant
    Filed: September 23, 2020
    Date of Patent: March 11, 2025
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Robert Stairs, James Reilly, John Mattila, Samantha Wadsworth
  • Patent number: 12246277
    Abstract: A sealing element (5) for a filter element (2) in a housing body (1) of a filtration device, preferably in a cross-flow filtration device. The sealing element (5) is of one-piece annular design and comprises a section for the sealing arrangement of the filter element (2) in the housing body (1) and a section for stop damping the filter element (2).
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: March 11, 2025
    Assignee: Bucher Unipektin AG
    Inventors: Ulrich Gans, Jürg Zuber, Bettina Mayer, Thomas Duss, Silvan Bruhin
  • Patent number: 12247553
    Abstract: A system for generating electricity and/or providing potable water. The system includes a subterranean shaft that extends into a geothermal reservoir and a volume of heat transfer fluid. Heat from the geothermal reservoir is transferred through a wall of the shaft and into the heat transfer fluid. The system includes a water intake conduit extending from the surface of the earth into the shaft interior. The water intake conduit includes proximal and distal ends and downward, return and upward portions. At least the return portion is positioned in the heat transfer fluid. Liquid water received through the proximal end of the water intake conduit moves downwardly along the downward portion and below the heat transfer fluid level. The liquid water is converted to steam via heat transfer from the heat transfer fluid through a wall of the water intake conduit. The steam moves upwardly along the upward portion of the water intake conduit and into the electrical generation stage, where electricity is generated.
    Type: Grant
    Filed: May 13, 2024
    Date of Patent: March 11, 2025
    Assignee: Stockton Geothermal Systems
    Inventor: Derric Juano
  • Patent number: 12245907
    Abstract: The disclosure relates to a dental debris separator having a housing in the upper region of which a drainage zone for removing particle-containing liquid from an air flow which is loaded with the liquid. The housing has an inlet for the loaded air flow, leading tangentially into the drainage zone. Downstream of the drainage zone a separation zone for removing the particles from the particle-containing liquid is provided in the housing, said separation zone descending from the drainage zone to the separation zone, the drainage zone having a curved flow path that is delimited on its lower side by a crown of baffle elements.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: March 11, 2025
    Inventor: Bruno Pregenzer
  • Patent number: 12246267
    Abstract: There is provided a chromatography system comprising a first valve in fluid connection to a first chromatography column and/or a second valve; the second valve in fluid connection to a second chromatography column and the first valve; wherein the first valve and the second valve are operable to provide: a mode that selectively allows a fluid to flow from the first chromatography column to the second chromatography column; and one or more modes that selectively allows the fluid to bypass the first chromatography column and/or the second chromatography column. Also disclosed is a method of capturing and/or purifying a target from a sample thereof. In one embodiment, an acidic protein, alpha-1 anti-trypsin (A1AT), is purified by a tandem column configuration using anion exchange chromatography, whereby a first chromatography column is added in between the sample pump and an injection valve, or replaced the sample loop of AKTA system.
    Type: Grant
    Filed: March 20, 2020
    Date of Patent: March 11, 2025
    Assignee: Agency For Science, Technology and Research
    Inventors: Zi Ying Zheng, Wei Zhang
  • Patent number: 12239110
    Abstract: A skimmer (1) for aquariums comprises a base (10) and a container (20) which is provided with at least two lateral connectors (21, 22) which comprise a main connector (22) and an auxiliary connector (21). The skimmer further comprises a cup (30), in which the foam is collected. The base comprises at least four openings, a first opening (11) and a second opening (12) opening inside the container (20) and being connected to a third opening (13) and a fourth opening (14), respectively, so that the skimmer can operate at least in two different configurations: a first single-pump configuration and a second double-pump configuration.
    Type: Grant
    Filed: November 19, 2020
    Date of Patent: March 4, 2025
    Assignee: SEACHEM LABORATORIES, INC.
    Inventors: Paolo Pettenon, Marco Pierobon, Federico Carraro, James A Rogers
  • Patent number: 12240771
    Abstract: A system for separating competing anions from per- and polyfluoroalkyl substances (PFAS) in a flow of water contaminated with PFAS and elevated levels of competing anions that includes a separation subsystem which receives the flow of water contaminated with PFAS and elevated levels of competing anions and separates competing anions from the PFAS and concentrates the PFAS to produce a treated flow of water having separated competing anions therein and a flow of water having a majority of PFAS therein. At least one anion exchange vessel having an anion exchange resin therein receives the flow of water having a majority of PFAS therein and removes PFAS from the water to produce a flow of treated water having a majority of the PFAS removed. The separation of competing anions by the separation subsystem increases the treatment capacity of the anion exchange resin to remove PFAS from the contaminated water.
    Type: Grant
    Filed: March 24, 2022
    Date of Patent: March 4, 2025
    Assignee: Emerging Compounds Treatment Technologies, Inc.
    Inventors: Steven E. Woodard, Michael G. Nickelsen, John C. Berry
  • Patent number: 12233383
    Abstract: Disclosed is a method of preparing a filtration membrane. The method includes providing a copolymer solution by dissolving a statistical copolymer in a mixture of a co-solvent and a first organic solvent, coating the copolymer solution onto a porous support layer to form a polymeric layer thereon, coagulating the polymeric layer on top of the support layer to form a thin film composite membrane, and immersing the thin film composite membrane into a water bath to obtain a filtration membrane. Also disclosed are a filtration membrane prepared by the method, and a process of filtering a liquid using the filtration membrane thus prepared.
    Type: Grant
    Filed: January 12, 2024
    Date of Patent: February 25, 2025
    Assignee: Trustees of Tufts College
    Inventors: Prity Bengani-Lutz, Ayse Asatekin Alexiou
  • Patent number: 12226557
    Abstract: The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.
    Type: Grant
    Filed: November 14, 2023
    Date of Patent: February 18, 2025
    Assignee: NxStage Medical, Inc.
    Inventors: Jeffrey H. Burbank, Dennis M. Treu, Daniel Joseph Rubery, Jr., Scott W. Newell, James M. Brugger, William J. Schnell, William K. Weigel, Steven A. White, Mark T. Wyeth, Jerome James, David Desouza, Joseph E. Turk, Jr., Garrett Casey
  • Patent number: 12227432
    Abstract: A filter cartridge, in particular gravity-operated filter cartridge, having a body portion with at least one water outlet and a head portion with at least one water inlet and at least one air outlet, the head portion being arranged on top of the body portion, the body portion and the head portion together forming a housing with an inner volume, the head portion having a lower rim defining a bottom opening of the head portion, the filter cartridge further having a mesh located in the inner volume and attached to the head portion along the lower rim, the mesh separating the inner volume into an upper volume defined by the mesh and the head portion and a lower volume defined by the mesh and the body portion, treatment media being arranged in the lower volume.
    Type: Grant
    Filed: July 10, 2020
    Date of Patent: February 18, 2025
    Assignee: BRITA SE
    Inventors: Phillip Bunnemann, Tobias Schuler, Falk Schuricht, Emre Oguz
  • Patent number: 12226724
    Abstract: A fluid filter for a motor vehicle includes a filter housing and a filter cartridge which is disposable in the filter housing. The filter housing has a housing pot and a covering element where the filter cartridge is connectable to the housing pot by rotating around a longitudinal axis of the filter cartridge. A holding element having a web is disposed on an end plate of the filter cartridge where the web protrudes from a wall of the holding element and where the wall is formed to be spiral shaped radially to the longitudinal axis. The web of the holding element is engageable behind a holding web in a mounting position of the filter cartridge where the holding web projects at a constant distance from a wall, formed to be spiral shaped radially to the longitudinal axis, of a counter bearing disposed on the housing pot.
    Type: Grant
    Filed: July 13, 2020
    Date of Patent: February 18, 2025
    Assignee: Daimler Truck AG
    Inventor: Eric Schumacher
  • Patent number: 12226721
    Abstract: A water filter buoy assembly includes a float, a frame for holding a filter, and at least one arm connecting the float to the frame.
    Type: Grant
    Filed: March 30, 2024
    Date of Patent: February 18, 2025
    Inventor: Christopher B Lewis
  • Patent number: 12227718
    Abstract: Surfactants capable of releasing and/or dissolving polymers to form water-soluble or water-dispersible polymer solutions are disclosed. In addition, polymer compositions containing a water-in-oil emulsion comprising the surfactant are provided and can be used, for example, in methods of dissolving a polymer. Also disclosed are detergent compositions and methods of cleaning articles and/or membranes using the surfactants herein. These surfactants and polymer compositions can be used in various industries including for water clarification, papermaking, sewage and industrial water treatment, drilling mud stabilizers, and enhanced oil recovery.
    Type: Grant
    Filed: November 6, 2023
    Date of Patent: February 18, 2025
    Assignee: Ecolab USA Inc.
    Inventors: Ashish Dhawan, Carter Martin Silvernail, Sukhwan Soontravanich, Ali Marie Bichler
  • Patent number: 12227442
    Abstract: Water treatment systems including electrically-driven and pressure-driven separation apparatus configured to produce a first treated water suitable for use as irrigation water and a second treated water suitable for use as potable water from one of brackish water and saline water and methods of operation of same.
    Type: Grant
    Filed: November 21, 2023
    Date of Patent: February 18, 2025
    Assignee: Evoqua Water Technologies LLC
    Inventors: Gary C. Ganzi, Frederick C. Wilkins
  • Patent number: 12226738
    Abstract: The present invention relates to a method for producing a porous membrane, the method being characterized in that a solvent system comprising 2-pyrrolidone and N-alkyl-2-pyrrolidone is used, wherein the content ratio of 2-pyrrolidone to N-alkyl-2-pyrrolidone in the solvent system is from 90%:10% to 10%:90%, based on mass %, and wherein N-alkyl-2-pyrrolidone is N-propyl-2-pyrrolidone and/or N-butyl-2-pyrrolidone. Furthermore, the present invention relates to a porous membrane obtainable by said method. Moreover, the present invention relates to the use of a specific solvent system for the production of a porous membrane.
    Type: Grant
    Filed: June 25, 2020
    Date of Patent: February 18, 2025
    Assignee: Sartorius Stedim Biotech GMBH
    Inventors: Jan Schwellenbach, Catharina Warnke, Sandra Otto
  • Patent number: 12226740
    Abstract: A macromolecule membrane structure (2) comprises a membrane (3) with water-channeling integral membrane proteins (IMPS) (1) and is coated, on a first surface, with a silica layer (4). The silica layer (4) stabilizes the macromolecule membrane structure (2) and the water-channeling IMPS (1) while maintaining the water-channeling function of the water-channeling IMPs (1). As a consequence of this stabilization, the macromolecule membrane structure (2) may be used in a filtration device (5) for various filtration operations, including water purification.
    Type: Grant
    Filed: February 26, 2020
    Date of Patent: February 18, 2025
    Assignee: Retein AB
    Inventors: Simon Isaksson, Martin Andersson
  • Patent number: 12220665
    Abstract: The disclosure provides tangential flow depth filtration (TFDF) systems which exhibit improved filter fluxes and process capacities and reduced fouling characteristics. The TFDF systems of the disclosure optionally utilize tubular depth filters (TDF). Methods are provided which include the passage of a non-laminar flow through at least a portion of a length of a TDF in a TFDF system.
    Type: Grant
    Filed: March 14, 2024
    Date of Patent: February 11, 2025
    Assignee: REPLIGEN CORPORATION
    Inventors: Michael Bransby, Derek Carroll, Philip Yuen, Ralf Kuriyel
  • Patent number: 12221362
    Abstract: A laser ablation and filtration process and apparatus wherein liquid containing hydrocarbons or other contaminants is purified. The liquid is exposed to laser energy at one or more selected wavelengths wherein the laser energy travels through the liquid and reaches the hydrocarbons or other contaminants and vaporizes, denatures, breaks down, neutralizes, renders inert and/or separates the hydrocarbons or contaminants from the liquid. A laser source is positioned in or on a vessel based on pre-set parameters to maximize exposure of the liquid to the laser energy, including sizing parameters, angle and inclination of the laser, retention time for the laser process to be applied and geometry of the containment for proper inclination. One or more collection chambers, which may include perforated membranes may be included to collect gases, separated hydrocarbons or contaminants and other by-products of the process. The vessel utilized may be submergible in water to pull or flow contaminated water therethough.
    Type: Grant
    Filed: August 7, 2023
    Date of Patent: February 11, 2025
    Inventors: Bartosz A. Dajnowski, Magdalena Dajnowski, Frank Richerand, Sr., Frank Richerand, II, Chuck Boutall
  • Patent number: 12214300
    Abstract: A sedimentation plate, a sedimentation assembly, and a sedimentation module are provided. The sedimentation plate includes a flat plate; a plurality of first rib plates arranged at intervals, parallel to each other, and perpendicular to a first surface of the flat plate; and a plurality of second rib plates arranged at intervals, parallel to each other, and perpendicular to a second surface of the flat plate. The first rib plates are perpendicular to the second rib plates. A water channel is formed between each two adjacent first rib plates. A mud channel is formed between each two adjacent second rib plates. The sedimentation assembly includes a plurality of sedimentation plates. The sedimentation module includes the sedimentation assembly.
    Type: Grant
    Filed: October 17, 2022
    Date of Patent: February 4, 2025
    Assignee: SHANDONG HOTONE ENVIRONMENTAL TECHNOLOGY CO., LTD.
    Inventors: Haofeng Luan, Shilian Mao, Jianmeng Du
  • Patent number: 12215460
    Abstract: In some embodiments, a method may include reducing the microbial load in contaminated water of water recycle loops. These water recycling loops may include pulp and paper mills, cooling towers and water loops, evaporation ponds, feedstock processing systems and/or non-potable water systems. The methods may include providing a peracetate oxidant solution. The peracetate solution may include peracetate anions and a peracid. In some embodiments, the peracetate solution may include a pH from about pH 10 to about pH 12. In some embodiments, the peracetate solution has a molar ratio of peracetate anions to peracid ranging from about 60:1 to about 6000:1. In some embodiments, the peracetate solution has a molar ratio of peracetate to hydrogen peroxide of greater than about 16:1. The peracetate solution may provide bleaching, sanitizing and/or disinfection of contaminated water and surfaces. The peracetate oxidant solution may provide enhanced separation of microbes from contaminated water.
    Type: Grant
    Filed: November 24, 2021
    Date of Patent: February 4, 2025
    Assignee: Clean Chemistry, Inc.
    Inventor: Wayne E. Buschmann