Abstract: Treatment with a cyclooxygenase-2 inhibitor and a leukotriene B4 receptor antagonist is described as being useful in reducing recipient rejection of transplanted organs and for treatment of autoimmune diseases.
Type:
Grant
Filed:
July 10, 2003
Date of Patent:
November 28, 2006
Assignee:
Pharmacia Corporation
Inventors:
Susan A Gregory, Peter G. Isakson, Gary Anderson
Abstract: Disclosed are pharmaceutical compositions comprising brimondine and timolol for topical ophthalmic delivery and a method of treatment comprising administering said composition when indicated for glaucoma and associated conditions such as elevated intraocular pressure in the eyes of humans.
Type:
Grant
Filed:
April 19, 2002
Date of Patent:
April 18, 2006
Assignee:
Allergan, Inc.
Inventors:
Chin-Ming Chang, Gary J. Beck, Cynthia C. Pratt, Amy L. Batoosingh
Abstract: The invention relates to compositions in the form of a powder or granules containing L-ascorbic acid and/or a pharmaceutically acceptable salt thereof, and pectin in a quantity within the range of about 0.1 to about 10% by weight.
Type:
Grant
Filed:
December 15, 2000
Date of Patent:
December 13, 2005
Assignee:
DSM Nutritional Products Inc.
Inventors:
Chyi-Cheng Chen, Bruno Leuenberger, Denise Voelki
Abstract: An antibiotic SF2487 substance having the formula (I) or a salt thereof possesses an antimalarial activity against the proliferation of malarial parasites and is therefore useful as an antimalarial drug.
Type:
Grant
Filed:
April 26, 2001
Date of Patent:
September 6, 2005
Assignee:
Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
Abstract: This invention is directed to a pharmaceutical composition comprising the sodium-hydrogen exchanger (NHE) inhibitor cariporide and an angiotensin converting enzyme (ACE) inhibitor which exhibits unexpectedly efficacious properties for preventing heart failure and other age-related organ dysfunctions, age-related disorders and for prolonging life, and to methods of preventing heart failure and other age-related organ dysfunctions, age-related disorders and for prolonging life comprising administering pharmaceutically effective amounts of the sodium-hydrogen exchange inhibitor cariporide and an ACE inhibitor.
Abstract: This invention discloses a method of orally administering arachidonic acid for the purpose of increasing the serum level of the prostaglandin PGF2alpha and subsequently the level of retained skeletal muscle mass.
Abstract: The present invention relates to a method for preventing or treating of cartilage related diseases, such as osteoarthritis, rheumatoid arthritis, articular cartilage damage, multiple chondritis, osteochondrosis, etc., which comprises administering an effective amount of calcium L-threonate to a subject in need of such prevention or treatment. It had been demonstrated by experiments that calcium L-threonate could improve significantly the positive expression percentage of collagen I mRNA in the chondrocyte and osteoblast, improved significantly the positive expression percentage of articular cartilage and epiphyseal cartilage, facilitated the growth of chondrocyte, increased the quantity of bone collagen, and promoted the formation of bone and cartilage matrix and the synthesis of proteoglycan. It could also promote the formation of bone nourishing blood vessels and improve the microcirculation of bone.
Abstract: A composition and method for preventing/reducing the severity of epithelial cytoxicity side effects such as alopecia, plantar-palmar syndrome, mucositis) induced by chemoptherapy and/or radiation therapy in a patient receiving such therapy wherein a cyclin-dependent kinase II inhibitor is contemporaneously administered to the patient.