Abstract: A biopsy device comprises a probe body, a cannula extending distally from the probe body, a cutter moveable relative to the cannula to sever tissue, and a tissue sample holder coupled with the probe body. The tissue sample holder comprises a rotatable member having a plurality of recesses to receive tissue samples. The rotatable member can be operable to successively index each recess relative to a lumen defined by the cutter. A cover portion may be associated with the rotatable member and permits one or more recesses to be viewable through the cover. The recesses may be configured to carry one or more tissue samples as the rotatable member is rotated.

Abstract: Medical devices for navigation through anatomy, including guidewires, which may have a core wire, a slotted tubular member, or both. Embodiments may have coils, including non-circular cross-section edge-wound marker coils, extended coil tips, and soldered or glued mesial joint coils. Core wires may have a step, ridge, or taper at the joints to the tubular member, and may be flattened at the distal tip. Radiopaque material may be located inside the tubular member, and the distal tip may be heat treated to make it shapeable. Additional tubular members or coils may be used concentrically or in line and may enhance flexibility, provide radiopacity, reduce friction, or reduce material or manufacturing cost. Tubular members may be chamfered or tapered continuously or incrementally. Slots may be arranged in groups, such as groups of three, and may be equal in depth or unequal in depth to provide a steerable or compressible tip.

Abstract: Plaque type determination devices, systems, and methods. In at least one exemplary embodiment of a device for assessing composition of a plaque of the present disclosure, the device comprises an elongate body having a longitudinal axis and a distal end, a first excitation electrode and a second excitation electrode located along the longitudinal axis of the body near the distal end of the elongate body, and a first detection electrode and a second detection electrode along the longitudinal axis of the body and in between the first and second excitation electrodes, wherein when a current source in communication with at least one of the first excitation electrode and the second excitation electrode applies current thereto to facilitate measurement of two or more conductance values within a vessel containing at least part of the elongate body at or near a plaque site, a plaque type determination can be made based upon a calculation of tissue conductance using at least one of the two or more conductance values.

Abstract: Embodiments of the present disclosure include a digit gauge used to ensure the size of a patient's digit is appropriate for the medical sensor applied thereto.

Abstract: Impedance devices for obtaining conductance measurements within luminal organs. In at least one embodiment of an impedance device of the present disclosure, the device, comprises an elongated body and an detector positioned upon the elongated body, the detector comprising at least five electrodes and configured to obtain one or more conductance measurements generated using a first arrangement of four of the at least five electrodes and further configured to obtain one or more fluid velocity measurements using a second arrangement of four of the at least five electrodes when the elongated body is positioned within a fluid environment of a mammalian luminal organ, wherein the first arrangement is different from the second arrangement.

Abstract: Medical devices for navigation through anatomy, including guidewires, which may have a core wire, a slotted tubular member, or both. Embodiments may have coils, including non-circular cross-section edge-wound marker coils, extended coil tips, and soldered or glued mesial joint coils. Core wires may have a step, ridge, or taper at the joints to the tubular member, and may be flattened at the distal tip. Radiopaque material may be located inside the tubular member, and the distal tip may be heat treated to make it shapeable. Additional tubular members or coils may be used concentrically or in line and may enhance flexibility, provide radiopacity, reduce friction, or reduce material or manufacturing cost. Tubular members may be chamfered or tapered continuously or incrementally. Slots may be arranged in groups, such as groups of three, and may be equal in depth or unequal in depth to provide a steerable or compressible tip.

Abstract: Methods, articles of manufacture, and systems for evaluating tinnitus are disclosed herein. According to various embodiments, a tinnitus evaluation system may include a tinnitus evaluation module configured to perform one or more tinnitus evaluation tests. A tinnitus evaluation test may comprise generating a first single-frequency sound based at least in part on a sound of a patient's tinnitus, and generating a narrow-band sound centered at the frequency of the first single-frequency sound. Tests include a hearing threshold test, a loudness match test, a pitch match test, a bandwidth match test, a minimum masking level test, and a residual inhibition test.

Abstract: Methods for measuring cross-sectional areas in luminal organs. In at least one embodiment of a method for measuring a size parameter of a targeted treatment site of the present disclosure, the method comprises the steps of introducing an impedance device into a treatment site, the impedance device selected from the group consisting of an impedance catheter and an impedance wire; injecting a first solution of a first compound having a first conductivity into the treatment site; measuring a first conductance value at the treatment site using the impedance device, the first conductance value indicative of a bolus of the first solution, and calculating a size parameter of the treatment site based in part upon the first conductivity of the first solution, the first conductance.

Abstract: A health sensing device is described for placement on a user. The device may include a sensor, a filter, and a transmitter. The sensor is configured to sense one or more factors relating to an indicator of a health related condition or occurrence. The filter is configured to evaluate a signal from the sensor and determine if the indicator has been detected. The transmitter is arranged for initiating a transmission based on a signal from the filter. The sensor can include one or more microphone devices, accelerometers, and/or MEMs devices. A method of monitoring a user for a health related condition is also described.

Abstract: A contact sensing assembly including a catheter including an electrode having a base portion mounted adjacent a head portion of the catheter body. A sensor is disposed adjacent the base portion for measuring compression or tensile forces applied to an electrode tip portion, and includes a predetermined sensitivity. The base and head portions include predetermined rigidity so that forces applied to the electrode tip portion are determinable as a function of the sensitivity and a sensor output. A contact sensing assembly also includes an electrode pipe operatively connected to the catheter body for movement and bending with the catheter body, and an electrode wire disposed in the electrode pipe and including insulation. A change in capacitance resulting from movement of the electrode wire toward the electrode pipe or contact of the electrode wire with the electrode pipe during bending of the catheter correlates to a force applied to the catheter.

Abstract: A lancet-sampler system is configured to automatically remove a protective cover from a lancet and automatically unpack a test pad just prior to use. This minimizes the risk of injury and reduces the chance of cross-contamination between the lancet and the test pad. The lancet defines a capillary groove for drawing body fluid from the incision via capillary action and a sample transfer opening for collecting the fluid from the groove. A carrier tape is coupled to the lancet. The carrier tape includes a test pad for analyzing the fluid. The tape is folded around the test pad to form an airtight package. The test pad is located at a position to align with the sample transfer opening when the tape is unfolded. The protective cover covers a portion of the lancet, and when the tape is pulled, the protective cover is automatically pulled from the lancet.

Abstract: A lancet housing assembly comprising multiple lancets for use in a portable handheld medical diagnostic device for sampling bodily fluids from a skin site of a patient is provided. The lancet housing assembly includes a housing structure comprising multiple lancet compartments. At least one of the lancet compartments comprises an outer facing side and an inner facing side. An opening is located at the outer facing side that is arranged and configured to align with a lancet port of the medical diagnostic device. A floor extends between the outer facing side and the inner facing side. A reagent material is located on the floor and within the lancet compartment. A lancet structure is located in the at least one lancet compartment. The lancet structure comprises a skin penetrating end and a blood transport portion adjacent the skin penetrating end. The skin penetrating end, when extended through the opening, is shaped and sized to penetrate the patient's skin at the skin site to provide an amount of blood.

Abstract: A method for the treatment of paralysis caused by injury to the brain. A set of movements by a healthy extremity is recorded and stored in a computer. Movements made by an affected extremity are recorded and compared to the standard provided by the healthy extremity. A score based on the similarity of the movement is reported to the user to aid in tracking progress. A similar system may also be used to detect and track the progress of degenerative diseases by comparing past movements to current movements.

Abstract: An implantable restriction device is configured to provide a restriction in a patient. A pressure sensor implanted in the patient is configured to sense pressure associated with the restriction device. A remote input device is configured to wirelessly receive pressure measurements from the pressure sensor and transmit the pressure measurements to a display device. The display device is configured to plot the pressure measurements as a function of time. The remote input device also includes buttons that may be used to annotate the pressure measurements, such as to indicate physical events associated with the patient (e.g., coughing, sneezing, etc.). The display device is also configured to display the annotations on or near the plot of pressure measurements. A viewer may thus take the annotations into account when evaluating the pressure measurements, such as by ignoring pressure measurements associated with certain types of annotations.

Abstract: The present application is directed to an image-guided, vacuum assisted, percutaneous, coring, cable driven breast biopsy instrument which may be conveniently mounted to an x-ray machine wherein the biopsy instrument incorporates a rotation knob at the proximal end of the instrument to manually rotate the distal end of the probe, thus allowing the clinician to conveniently position the tissue port next to the tissue to be sampled.

Abstract: This invention pertains generally to non-invasive methods and apparatus for analyzing and improving human balance. More particularly, this invention describes a human balance analysis and improvement apparatus and method that involves the use of separate and synergistically integrated and combined means for analyzing and producing perfect core body alignment and balance: an alignment indicator, sway measurement apparatus, and foot force measurement and force centering apparatus. Data received from the aforesaid devices or various combinations thereof is then integrated and displayed by appropriate software and/or display apparatus for use in perfecting, analyzing and/or correcting human balance. The alignment and sway measurement apparatus of the invention is preferably subject based upon video motion capture technology.

Abstract: A system and method is disclosed for measuring muscle reflexes (e.g., a bulbocavernosus reflex) as a tool for identifying/diagnosing dysfunctions (e.g., spinal cord abnormalities, bladder voiding dysfunction, and sexual organ dysfunction) non-invasively by using mechanical stimulation. The system and method includes a probe having a predetermined patient contacting portion, wherein when the contacting portion is moved into contact with a particular area of the patient (e.g., the patient's genitals), the contact induces a muscle reflex. The probe detects the pressure resulting from the contacting portion being abruptly and forcibly brought into contact with the particular area. Such detection is used to electronically initiate capture of electrical responses from a plurality of electrodes placed on the patient's skin in proximity to the particular area. Such electrical responses are processed to determine characteristics of the patient's reflexes of one or more muscles adjacent to the electrodes.

Abstract: A medical guidewire having distal tip coil that includes a twisted ribbon wire construction. The distal tip coil is mounted to the distal end of the distal core section of the guidewire. The coil is made from a flat ribbon wire with a polygonal, preferably rectangular, cross-section that is twisted along the length of the wire. The twisted, flat ribbon wire creates a tip coil that has a roughened, undulating surface at the outer circumference that, whether coated or bare, is perceptible to the physician or cardiologist when pushing or torquing the guidewire in an interventional procedure.

Abstract: A biopsy device comprises a body, a needle, and a cutter actuation mechanism. The needle extends distally from the body. The cutter actuation mechanism rotates and translates the cutter relative to the body and relative to the needle. The cutter has an overmold presenting a lead screw and a hex portion. The cutter actuation mechanism comprises a first gear disposed about the hex portion of the overmold and a second gear engaged with the lead screw of the overmold by a nut that is integral with the second gear. The cutter actuation mechanism is operable to simultaneously rotate the first gear relative to the body at a first rotational speed and the second gear relative to the body at a second rotational speed. With the lead screw and the nut rotating at different rotational speeds, the lead screw rotates relative to the nut at a third rotational speed.

Abstract: Transvaginal probes equipped with tactile sensors are configured for placement into vagina to record tactile response during insertion, acquire static tactile pattern from vaginal wall after the insertion is complete, and acquire dynamic tactile patterns during probe motion as well as recording dynamic tactile response during contraction of vaginal muscle. The acquired and recorded tactile data are transmitted to a data processor for composing tactile profile of vagina and visually presenting thereof on a display. Elasticity profile of vaginal tissue is calculated from the tactile response recorded from different parts of the probe during its insertion, from the static pressure pattern and from the dynamic tactile pattern. Pelvic floor muscle strength is defined as a contact pressure increase detected on fixed probe surface under the muscle contraction. Tactile profile of vagina is determined using the static tactile pattern, the elasticity profile and pelvic floor muscle strength.