Abstract: Novel 1-[1-(hetero)aryl-1-perhydroxyalkylmethyl]-piperazine compounds which are antagonistic to tachykinin receptors, of the general formula I,
wherein R6, R7, A and Z have the meanings given in the description, and pharmaceutical compositions containing these compounds, as well as a process for the preparation of such compounds and intermediate products of this process.
Type:
Grant
Filed:
September 13, 2002
Date of Patent:
August 3, 2004
Assignee:
Solvay Pharmaceuticals GmbH
Inventors:
Daniel Jasserand, Ulf Preuschoff, Jochen Antel, Samuel David, Holger Sann, Reinhard Brueckner, Dania Reiche, Christian Eeckhout
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