Abstract: This invention relates to novel azetidines and derivative thereof, as well as to pharmaceutical compositions and methods of treating memory and learning disorders. Another aspect of the invention relates to a method of utilizing the compounds and compositions as biological tools and materials for characterizing excitatory amino acid receptor systems. A further aspect of the invention relates to a method of treating PCP toxicity and abuse.
Type:
Grant
Filed:
July 17, 1987
Date of Patent:
August 7, 1990
Assignee:
Fidia-Georgetown Institute for the Neurosciences
Inventors:
Alan P. Kozikowskip, Jarda T. Wroblewski, Erminio Costa