Patents Examined by C. Delacroix-Muirhead
  • Patent number: 6669995
    Abstract: A method of treating an anti-reflective coating on a substrate. The method includes exposing the anti-reflective coating to a dosage of ultraviolet radiation sufficient to result in the direct removal of at least a portion of the exposed anti-reflective coating.
    Type: Grant
    Filed: October 12, 1994
    Date of Patent: December 30, 2003
    Inventors: Linda Insalaco, James Mitchener
  • Patent number: 6214796
    Abstract: The present invention relates to the treatment of central nervous system injuries by intracisternal or intravenous administration of polypeptide growth factors, such as basic fibroblast growth factor. This method provides significant benefits because administration can occur a substantial amount of time following an injury.
    Type: Grant
    Filed: March 21, 1997
    Date of Patent: April 10, 2001
    Assignee: The General Hospital Corporation
    Inventor: Seth P. Finklestein
  • Patent number: 6211335
    Abstract: A method for joining tissue comprising aligning and abutting edges of the tissue to be joined applying biodegradable, biological solder or an analogue thereof, across the edges and exposing the solder to an energy source under conditions which provide transfer of energy from the source to the solder to cause the solder to bond to the tissue surface adjacent the edges to provide a weld holding the edges together.
    Type: Grant
    Filed: October 17, 1997
    Date of Patent: April 3, 2001
    Assignees: The Microsearch Foundation of Australia, Macquarie Research Ltd.
    Inventors: Earl Ronald Owen, Rodney Ian Trickett, Antonio Lauto, Judith Margaret Dawes, James Austin Piper
  • Patent number: 6143757
    Abstract: Compounds of the general structural formula ##STR1## and use of the compounds and salts and solvates thereof, as therapeutic agents.
    Type: Grant
    Filed: September 16, 1998
    Date of Patent: November 7, 2000
    Assignee: ICOS Corporation
    Inventors: Alain Claude-Marie Daugan, Richard Frederick LaBaudiniere
  • Patent number: 6143864
    Abstract: Oligopeptides which comprise amino acid sequences that are recognized and proteolytically cleaved by free prostate specific antigen (PSA) are described. Also described are assays which comprise such oligopeptides useful for determining free PSA protease activity in vitro and in vivo. Therapeutic agents which comprise conjugates of such oligopeptides and known cytotoxic agents are also described.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: November 7, 2000
    Assignee: Merck & Co., Inc.
    Inventors: Deborah DeFeo-Jones, Dong-Mei Feng, Victor M. Garsky, Raymond E. Jones, Allen I. Oliff
  • Patent number: 5914316
    Abstract: A method is disclosed for inhibiting intimal hyperplasia in a warm-blooded mammal which comprises administering topically at the site and time of a vascular injury induced by arterial intervention in said mammal a small but inhibitorily effective amount of tissue factor pathway inhibitor (TFPI) sufficient to inhibit said intimal hyperplasia.
    Type: Grant
    Filed: September 25, 1996
    Date of Patent: June 22, 1999
    Assignee: Washington University
    Inventors: David M. Brown, Tze-Chein Wun, Roger K. Khouri
  • Patent number: 5674840
    Abstract: Synthetic aglucodalbaheptides of formula (I) wherein W and Z, each independently, represent the relative portions of the aglycon of an antibiotic of the dalbaheptide group. Y represents a carboxylic group or a functional derivative of said carboxylic group; R and R.sub.1, each independently, represent hydrogen or a protecting group of the amino function. R.sub.2 represents hydrogen; and their salts with acid and bases as well as their inner salts. A process for producing the aglucodabaheptides of formula (I) and their use as medicaments.
    Type: Grant
    Filed: December 26, 1995
    Date of Patent: October 7, 1997
    Assignee: Gruppo Lepetit SpA
    Inventors: Adriano Malabarba, Romeo Ciabatti
  • Patent number: RE36826
    Abstract: An electrophoresis pattern reading system of fluorescent type is comprised of a detachable migration unit comprising a gel functioning as a base for electrophoresis and a gel-supporting body for supporting the gel; an electrophoresis unit, to which the migration unit is mounted, for performing electrophoresis by applying migrating voltage to the gel to which a sample labeled with a fluorescent substance is added; and a reading unit including an instrumentation subunit for reading an electrophoresis pattern, to which the migration unit is mounted after electrophoresis and which receives fluorescence emitted from the fluorescent substance of the sample on the gel upon application of light to the gel.
    Type: Grant
    Filed: December 3, 1993
    Date of Patent: August 22, 2000
    Assignee: Hitachi Software Engineering Co., Ltd.
    Inventors: Hitoshi Fujimiya, Shigeo Nakajima, Hisanori Nasu, Keigi Koga