Patents Examined by C. Fred Rosenbaum
-
Patent number: 5470309Abstract: A medical probe device including a catheter having a stylet guide housing with one or more stylet ports in a side wall thereof and guide means for directing a flexible stylet outward through the stylet port and through intervening tissue to a target tissue. The catheter assembly includes a stylet guide lumen communicating with the stylet port and a stylet positioned in said stylet guide lumen for longitudinal movement from the port through intervening tissue to a target tissue. The stylet can be an electrical conductor enclosed within a non-conductive layer, the electrical conductor being a radio frequency electrode. In normal action, the stylet and its surrounding sleeve are deployed out from the stylet port in the catheter into the desired target tissue. A sharpened tip on the stylet electrode facilitates the penetration of the intervening tissue, such as a urethra.Type: GrantFiled: January 12, 1994Date of Patent: November 28, 1995Assignee: Vidamed, Inc.Inventors: Stuart D. Edwards, Ronald G. Lax, Ingemar H. Lundquist, Hugh R. Sharkey
-
Patent number: 5470317Abstract: The invention relates to an inflation syringe assembly, which includes a housing having a barrel portion defining an interior space; a pressure gauge mounted to the barrel portion; a plunger disposed in the barrel portion; and structure for advancing the plunger in the barrel portion, wherein the barrel portion is rotatable relative to the housing so that the barrel portion with the pressure gauge is rotatable to a desired position relative to the housing.Type: GrantFiled: August 2, 1994Date of Patent: November 28, 1995Assignee: Design Standards CorporationInventors: John J. Cananzey, Scot M. Lucey
-
Patent number: 5468223Abstract: This invention provides for methods of introducing anti-cancer agents directly into cancer cells by increasing the permeability of cell walls through the use of electric pulses.Type: GrantFiled: November 30, 1992Date of Patent: November 21, 1995Assignee: C.N.R.S. ParisInventor: Lluis Mir
-
Patent number: 5468225Abstract: An over-the-wire rapid-exchange catheter having a distal guidewire channel and a proximal guidewire channel. The catheter is exchanged by withdrawing the catheter from a guiding catheter until the guidewire can be removed from the proximal guidewire channel and then further withdrawn in the conventional fashion. The proximal guidewire channel provides a sealing surface for a releasable seal on the guiding catheter, avoiding the gripping of the guidewire.Type: GrantFiled: February 17, 1994Date of Patent: November 21, 1995Inventor: Paul S. Teirstein
-
Patent number: 5468224Abstract: Injectable medications are color coded by adding harmless coloring materials to the medications themselves. In one embodiment of the invention, each medication is assigned a color. In another embodiment, a class of medications is assigned a color.Type: GrantFiled: January 23, 1995Date of Patent: November 21, 1995Inventor: Tarek O. Souryal
-
Patent number: 5467763Abstract: A surgical instrument includes a plurality of segments which can be moved relative to each other from a first position in which the segments extend in a straight direction and can be inserted through an opening in a body to a second position in which segments are brought tight against each other to cause the instrument to go round a bend. The segments are brought tight against each other by pulling a flexible element extending through the segments from a part of the instrument located outside of the body. Scissors or gripping means may be located at the free end of the instrument within the body, and these scissors or gripping means may be operated from outside of the body.Type: GrantFiled: July 20, 1994Date of Patent: November 21, 1995Inventors: Michael J. McMahon, Peter Moran
-
Patent number: 5468233Abstract: A hypodermic dosage measuring device to be utilized with a hypodermic syringe and a conventional drug vial, the dosage measuring device including a vial holding portion adapted to hold a head of the drug vial non-slidably therein, a syringe holding portion adapted to hold the syringe in a non-slidable position with a needle of the syringe disposed within the drug vial, and a dose adjustment portion, the dose adjustment portion including an elongate plunger holder and gear element, the plunger holder and gear element each including a plurality of teeth thereon such that movement of the gear element results in an elongate track segment of the plunger holder sliding in a longitudinal direction parallel to a length of the syringe.Type: GrantFiled: December 6, 1993Date of Patent: November 21, 1995Inventor: Steven Schraga
-
Patent number: 5468221Abstract: Implantable catheter made of medically tolerated synthetic material, whose thermoplastic polymer has an excellent cold flow at 34.degree. C. to 40.degree. C. under a weight load of 40 g/0.2 mm.sup.2, so that, in the case of a continuous tensile load for 63 days, the initial length of the catheter increases by at least 50% in the direction of the longitudinal axis, the extruded catheter tube consisting of three layers connected to each other and arranged coaxially, and the middle layer containing a radiopaque pigment.Type: GrantFiled: June 20, 1994Date of Patent: November 21, 1995Inventor: Wolfgang Schoner
-
Patent number: 5468232Abstract: A cartridge-type syringe in which a cartridge, having liquid medicine or the like sealed therein, is inserted in a holder having a discharge needle at its distal end, and the cartridge is advanced to cause the discharge needle to pierce it, thereby injecting the liquid medicine or the like into an object, and when a piston rod of the cartridge is pushed to cause the discharge needle to pierce, the liquid medicine or the like will not be discharged in error in a large amount.In particular there is provided a releaseable lock mechanism by which when a piston rod 15 is pushed, the piston rod 15 advances together with a tubular body 11 of a cartridge 10 without moving a piston 14 within the tubular body 11.Type: GrantFiled: January 27, 1993Date of Patent: November 21, 1995Assignee: Seikagaku Kogyo Kabushiki Kaisha(Seikagaku Corporation)Inventor: Masateru Naganuma
-
Patent number: 5466216Abstract: An antegrade/retrograde cardioplegia valve, system and method are provided. The valve includes conduits for entry of blood and cardioplegic solution, for pressure sensing, and for delivery of blood and cardioplegic solution to the aortic root by means of an aortic root cannula for antegrade infusion or to the coronary sinus by means of a coronary sinus cannula for retrograde infusion. Within the valve a cylindrical sliding member slides axially within an inner cylindrical chamber for selection of retrograde or antegrade infusion. An independent conduit communicates with the coronary sinus cannula for continuous coronary sinus pressure monitoring. A method and system incorporating the valve are also provided.Type: GrantFiled: April 11, 1994Date of Patent: November 14, 1995Assignee: Gish Biomedical, Inc.Inventors: Jack W. Brown, Brian Strauss, George W. White
-
Patent number: 5466230Abstract: A catheter sheath introducer comprising a tubular sheath having a proximal end and a distal end are provided. A hub is coupled to the proximal end of the tubular sheath and a coil spring is also provided. The coil spring is positioned about the proximal end of the tubular sheath, and the sheath and coil spring are coupled to the hub in such a way that the tubular sheath and coil spring extend within the hub and out from the hub whereby the strain produced when the tubular sheath and hub are moved relative to one another is relieved.Type: GrantFiled: June 9, 1994Date of Patent: November 14, 1995Assignee: Cordis CorporationInventor: Luis A. Davila
-
Patent number: 5466220Abstract: A drug vial mixing and transfer device having a piercing connector or a syringe attached to the end of one or more ports with interconnecting fluid passageways. Further, the piercing connector is used to support and penetrate standard glass drug vials filled with powder or lyophilized drugs or liquid diluent, while the syringe is used to transfer liquid diluent and drug solutions between the vials and the syringe advantageously within a sealed system.Type: GrantFiled: March 8, 1994Date of Patent: November 14, 1995Assignee: Bioject, Inc.Inventor: Rodney Brenneman
-
Patent number: 5466227Abstract: An injector assembly and method are provided for assembling the injector assembly to a patient controlled analgesic infuser unit. The injector assembly is provided in one-piece and includes an injector element having first and second portions with a cannula extending therebetween. The first portion is configured for connection to a stopper of a vial containing an analgesic where the connection enables the analgesic to flow out of the vial and through the cannula to the second portion of the injector element upon advancement of the stopper and the connected injector element within the vial by the infuser unit. A drug administration set is permanently connected to the second portion of the injector element for receiving the analgesic from the cannula.Type: GrantFiled: January 10, 1994Date of Patent: November 14, 1995Assignee: Abbott LaboratoriesInventor: Peter Kessenich
-
Patent number: 5466217Abstract: An iontophoretic agent delivery device having a simplified structure and ease of manufacture. The device utilizes an electrical pathway comprising a source of electrical energy and an output means. The electrical pathway is disposed upon one of the two sides of a flexible, non-conductive substrate (e.g., a film). The output means of the pathway are connected directly or indirectly, e.g., by means of an electrically conductive adhesive tape, to the remaining components of the device such as current distribution members, lead wires, or electrodes. In this arrangement, the circuit is inverted from that of conventional devices. Economical, reel-to-reel methods of manufacturing a one-sided iontophoretic circuit apparatus of the invention are disclosed.Type: GrantFiled: April 4, 1994Date of Patent: November 14, 1995Assignee: Alza CorporationInventors: Robert M. Myers, Ronald P. Haak, Richard W. Plue
-
Patent number: 5466233Abstract: A tack for intraocular drug delivery and a method for insertion and removal of an intraocular device for sustained release of a drug are provided. The tack comprises a post, an anchoring region and a head. The post is for being positioned within the vitreous region of the eye. The post has a first end and a second end, and includes a drug to be administered. The anchoring region is affixed to the second end of the post, and includes a width measured perpendicularly to a longitudinal axis of the tack which varies to provide the anchoring region with a configuration to anchor the tack within at least one of a sclera, a retina and a choroid. The head extends radially outwardly from the anchoring region such that upon insertion of the anchoring region and post within the eye, the head remains external to the eye and abuts a scleral surface of the eye. Other embodiments include a tack comprising a post, a central portion, a head and a suture hole through the head for anchoring the head to the sclera.Type: GrantFiled: April 25, 1994Date of Patent: November 14, 1995Assignee: Escalon Ophthalmics, Inc.Inventors: Alan L. Weiner, Kevin Sinnett, Sterling Johnson
-
Patent number: 5464393Abstract: A pill crushing syringe is disclosed which includes a barrel and a plunger, with abraded surfaces on each so that a pill placed in the barrel is crushed as the plunger advances within the barrel. The barrel has an aperture located near the closed end with a catheter connected around and extending from the aperture. The plunger has a sealing gland to provide an airtight seal with the barrel so that liquid may be drawn into the barrel through the aperture by withdrawing the plunger from the barrel to thereby suspend the crushed pill in the liquid, and the suspension may be flushed from the barrel by thereafter advancing the plunger into the barrel. In an alternative embodiment, a bi-level barrel has an aperture in spaced relation to the closed end forming a pocket wherein the crushed pill ingredients accumulate. The pocket at the closed end and the separation between the aperture and the barrel closed end helps prevent the medication from escaping the barrel via the catheter prior to aspiration.Type: GrantFiled: June 23, 1994Date of Patent: November 7, 1995Assignee: Lake Medical Products, Inc.Inventors: Jeffrey D. Klearman, Jeffrey J. Bierman, Eli Schachet
-
Patent number: 5464387Abstract: A transdermal drug delivery device (20) is provided having both an active drug reservoir (24) and a passive drug reservoir (26). Drug is actively delivered by iontophoresis from the active drug reservoir (24) by an electric field generated by a power source (21). Simultaneously, drug is delivered from passive reservoir (26) by passive (i.e., non-electrically assisted) diffusion. In one embodiment, the passive drug reservoir (26) is electrically insulated from the active drug reservoir (24). In a second embodiment, both the active and the passive drug are contained in the same reservoir (34). In the second embodiment, the active drug is ionizable while the passive drug is non-ionizable. Most preferably, the active drug is an ionizable form (i.e., a salt form) of the passive drug.Type: GrantFiled: October 27, 1994Date of Patent: November 7, 1995Assignee: Alza CorporationInventors: Ronald P. Haak, Felix Theeuwes, J. Richard Gyory, Gary A. Lattin
-
Patent number: 5464398Abstract: A catheter (1, 18) is essentially rigid in cross-section in the peripheral region, and has at least two lumina (3, 4, 19, 20), which are mutually separated by a wall (2, 21) which can be expanded and/or deformed in the transverse plane. The flow cross-sections of the lumina change owing to the deformation of the separating wall (2, 21), depending on the prevailing differential pressure. If drugs are introduced through the lumina one after another, then there is used, in the lumen, an over pressure in relation to the other lumen or lumina, which causes a deformation of the separating wall (2, 21), and hence a reduction in the resistance to flow. The catheter (24) can, therefore, be given a smaller cross-section than that of the prior art multi-lumen catheters (32, 33, 34), resulting in easier manipulation by the doctor and less risk for the patient.Type: GrantFiled: July 23, 1993Date of Patent: November 7, 1995Inventor: Hans Haindl
-
Patent number: 5464388Abstract: A cardioplegia administration system includes a tubing set, a positive displacement pump and a mixing system. The tubing set has a cardioplegia supply tube; a blood supply tube; and a cardioplegia administration tube connected to the cardioplegia and blood supply tubes. The positive displacement pump engages the cardioplegia administration tube to pump fluid therethrough. The mixing system includes pinch valves for alternately-continually pinching the cardioplegia and blood supply tubes to close and open the cardioplegia and blood supply tubes such that only one of the cardioplegia and blood supply tubes is open at a time, and a controller that controls the intervals during which the pinch valves are open to control the ratio of the cardioplegia medication and blood or blood substitute administered through the cardioplegia administration tube.Type: GrantFiled: February 6, 1995Date of Patent: November 7, 1995Assignee: Minnesota Mining and Manufacturing CompanyInventors: Kenneth E. Merte, William G. O'Neill
-
Patent number: 5464399Abstract: A quick-connect, needleless coupling assembly configured to shield its critical areas from contamination by environmental surfaces has a pair of interlocking, flow-through male and female components which may be used as part of a larger medicinal liquid therapy system. The male component has a generally rigid, blunt, open-ended cannula which is recessed with respect to a surrounding concentrically spaced collar so that the open end of the cannula is protected against contact from environmental surfaces which might otherwise contaminate the cannula. The female component has a socket which receives the male cannula to place the two components into liquid flow communication with one another.Type: GrantFiled: May 25, 1993Date of Patent: November 7, 1995Assignee: St. Francis Research InstituteInventor: Conrad H. Boettger