Patents Examined by C. Kalita
  • Patent number: 4452981
    Abstract: A condensed phenylurazol of the formula: ##STR1## wherein X is a chlorine atom or a bromine atom, Y and Z are each an oxygen atom or a sulfur atom and R is a C.sub.1 -C.sub.3 alkyl group, an allyl group or a propargyl group and n is an integer of 4 or 5, which is useful as a herbicide.
    Type: Grant
    Filed: September 15, 1982
    Date of Patent: June 5, 1984
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Eiki Nagano, Shunichi Hashimoto, Ryo Yoshida, Hiroshi Matsumoto, Katsuzo Kamoshita
  • Patent number: 4450271
    Abstract: An improved procedure for the manufacture of 2-hydroxyquinoxalines from reacting a dialkyl tartrate with a periodate, adjusting the pH of the resulting reaction mixture, and condensing said mixture with an o-phenylenediamine.
    Type: Grant
    Filed: July 19, 1982
    Date of Patent: May 22, 1984
    Assignee: Industrial Technology Research Institute
    Inventors: Tsung-Tsan Su, Yu-Chen Cheng
  • Patent number: 4450272
    Abstract: This disclosure describes 4-heteroaryl-1-piperazinethiocarboxamides useful in the treatment of atherosclerosis in mammals.
    Type: Grant
    Filed: May 6, 1982
    Date of Patent: May 22, 1984
    Assignee: American Cyanamid Company
    Inventors: Mila T. Du, Robert G. Shepherd
  • Patent number: 4447365
    Abstract: Described are the alkyl and bicycloalkyl methyl carbonates defined according to the structure: ##STR1## wherein R represents 2-ethyl hexyl, having the structure: ##STR2## or isobornyl having the structure: ##STR3## and uses thereof in augmenting or enhancing the aroma of perfume compositions, colognes and perfumed articles.
    Type: Grant
    Filed: January 18, 1983
    Date of Patent: May 8, 1984
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Richard M. Boden, Michael Licciardello, Theodore J. Tyszkiewicz
  • Patent number: 4446323
    Abstract: Tetra- and hexa-hydropyrrolo[1,2-a]quinoxaline and azaquinoxaline derivatives of the formula: ##STR1## in which X is O or H.sub.2 ;Y is CH or N;R is hydrogen, alkyl, dialkylaminoalkyl, arylalkyl, phenoxyalkyl, benzoyl, pyridylalkyl or variations thereof; andR.sup.1 is hydrogen, alkyl, alkoxy, nitro, halo, trifluoromethyl, amino, alkylamino or dialkylamino;or pharmaceutically acceptable salts thereof; are anti-hypertensive agents.
    Type: Grant
    Filed: May 23, 1983
    Date of Patent: May 1, 1984
    Assignee: American Home Products Corporation
    Inventors: Meier E. Freed, Magid Abou-Gharbia
  • Patent number: 4442111
    Abstract: Compounds of the formula ##STR1## wherein n is 0 or 1;A is methylene, vinylene or ethylene optionally substituted by lower alkyl;B is alkylene;R.sub.1 is an optionally substituted alkyl, phenyl or naphthyl group, or a cycloalkyl or pyridyl group; andR.sub.2 is hydrogen or acyl;and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as antithrombotics.
    Type: Grant
    Filed: July 6, 1982
    Date of Patent: April 10, 1984
    Assignee: Dr. Karl Thomae Gesellschaft mit beschrankter Haftung
    Inventors: Erich Muller, Josef Nickl, Berthold Narr, Josef Roch, Walter Haarmann, Johannes M. Weisenberger
  • Patent number: 4440930
    Abstract: Disclosed are certain herbicidally active quinoline or quinoxaline acetophenone oxime derivatives, herbicidal compositions containing these compounds and the use of such compounds to control the growth of noxious plants, i.e., weeds.
    Type: Grant
    Filed: October 25, 1982
    Date of Patent: April 3, 1984
    Assignee: PPG Industries, Inc.
    Inventors: Dennis K. Krass, Sidney B. Richter
  • Patent number: 4439606
    Abstract: This disclosure describes 4-aryl, -heteroaryl and -heteroarylmethyl-1-piperazinecarbonyl compounds which are capable of ameliorating atherosclerosis in mammals.
    Type: Grant
    Filed: May 6, 1982
    Date of Patent: March 27, 1984
    Assignee: American Cyanamid Company
    Inventors: Mila T. Du, Robert G. Shepherd
  • Patent number: 4435331
    Abstract: Described is the methyl carbonate of .alpha.,3,3-trimethyl cyclohexane methanol defined according to the structure: ##STR1## and uses thereof in augmenting or enhancing the aroma of perfume compositions, colognes and perfumed articles such as solid or liquid anionic, cationic, nonionic or zwitterionic detergents, fabric softeners, fabric softener articles as well as hair sprays, shampoos and bath oils and perfumed polymers. Also described is a process for preparing the methyl carbonate of .alpha.
    Type: Grant
    Filed: March 10, 1983
    Date of Patent: March 6, 1984
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Michael Licciardello, Richard M. Boden
  • Patent number: 4430502
    Abstract: The present invention provides novel pyridinyl-benzimidazoles and quinoxalines which are useful as thromboxane A.sub.2 (TXA.sub.2) synthetase inhibitors and as such represent potent pharmacological agents.
    Type: Grant
    Filed: August 13, 1982
    Date of Patent: February 7, 1984
    Assignee: The Upjohn Company
    Inventor: Norman A. Nelson
  • Patent number: 4426391
    Abstract: Novel prodrugs of methyldopa which are [(alkoxycarbonyl)oxy]alkyl esters of methyldopa are disclosed. Also, pharmaceutical compositions containing these compounds are disclosed. Upon administration to warm-blooded animals, these prodrugs liberate methyldopa along with innocuous side products.
    Type: Grant
    Filed: September 15, 1982
    Date of Patent: January 17, 1984
    Assignee: Merck & Co., Inc.
    Inventors: Jose Alexander, Chung Shih
  • Patent number: 4426331
    Abstract: A process for the oxidative carbonylation of an alcohol to produce a carbonate, which comprises reacting together carbon monoxide, oxygen and an alcohol, in the presence of a copper compound and in the presence of a sulfone.
    Type: Grant
    Filed: July 19, 1982
    Date of Patent: January 17, 1984
    Assignee: Shell Oil Company
    Inventor: Eit Drent
  • Patent number: 4414389
    Abstract: The compounds ##STR1## where R is hydrogen, alkyl, phenyl or substituted phenyl and R.sup.1 is 2-furanyl, 2-benzofuranyl, 2-thienyl or 2-pyridyl or pharmaceutically acceptable salts thereof are antihypertensive, antisecretory agents.
    Type: Grant
    Filed: May 25, 1982
    Date of Patent: November 8, 1983
    Assignee: American Home Products Corporation
    Inventor: Meier E. Freed
  • Patent number: 4397789
    Abstract: Described are the 4-cyclooctenyl lower alkyl carbonates reaction products including a major proportion of said 4-cyclooctenyl alkyl carbonates and a minor proportion of bicyclooctanyl carbonates having the structure: ##STR1## wherein R.sub.5 is methyl or ethyl, said mixture being produced by: first reacting 1,5-cyclooctadiene with formic acid to form a mixture of 4-cyclooctenyl formate in a major proportion and bicyclooctanyl formate in a minor proportion and then reacting the resulting mixture with an alkyl carbonate in the presence of an alkali metal alkoxide to form a mixture of compounds defined above and uses thereof in augmenting or enhancing the aroma of perfume compositions, colognes and perfumed articles such as solid or liquid anionic, cationic, nonionic or zwitterionic detergents, fabric softeners, fabric softener articles, hair sprays, shampoos, bath oils and perfumed polymers.
    Type: Grant
    Filed: August 19, 1982
    Date of Patent: August 9, 1983
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Richard M. Boden, Michael Licciardello
  • Patent number: 4395556
    Abstract: Nitrobenzofurazan derivatives having the formula ##STR1## are provided wherein R.sub.1 and R.sub.2 each is hydrogen, lower alkyl or phenyl-lower alkyl; R.sub.3 is hydrogen, hydroxy or lower alkyl; R.sub.4 is hydrogen or lower alkyl; m is 2 or 3; and n is 0, 1 or 2; these compounds are useful analytical tools.
    Type: Grant
    Filed: February 4, 1982
    Date of Patent: July 26, 1983
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Callixtus E. Ita, Anthony F. Heald, Peter Egli