Abstract: Provided are an electrolyte analysis device and a method for identifying an abnormality in the same that make it possible to detect an abnormality in an ion-selective electrode at an early stage. The electrolyte analysis device comprises an ion-selective electrode that generates a sample potential that is a potential corresponding to the ion concentration of a sample, a reference electrode that generates a reference potential that is a potential to serve as a reference, and a concentration calculation unit that calculates the ion concentration on the basis of the potential difference between the sample potential and the reference potential. The electrolyte analysis device is characterized by additionally comprising an abnormality determination unit for determining whether there is an abnormality on the basis of an evaluation value that has been calculated using a detergent potential that is a potential generated by the ion-selective electrode when a detergent was supplied.

Abstract: The present technology relates to improved device and methods of use of insulator-based dielectrophoresis. This device provides a multi-length scale element that provides enhanced resolution and separation. The device provides improved particle streamlines, trapping efficiency, and induces laterally similar environments. Also provided are methods of using the device.

Abstract: An electrochemical biosensor has an electrode which is sequentially decorated a molybdenum (VI) oxide (MoO3) nanomaterial, a gold-composite nanomaterial, a carboxyl-sulfhydryl compound, and a carbodiimide/N-hydroxysuccinimide (EDC/NHS, EN) to modify the surface of the electrode. That the sulfhydryl group of the carboxyl-sulfhydryl compound forms a bond with the gold-composite nanomaterial, and the carbodiimide/N-hydroxybutanediimide forms a bond with a carboxyl group of the carboxyl-sulfhydryl compound.

Abstract: The invention relates to a comparison unit (130) configured for determining if a first pH measuring device of a first tank (104; 106) is affected by a pH-measuring problem, the comparison unit being configured for: receiving a first CO2 concentration and a first pH value, the first CO2 concentration being a CO2 concentration of a first gas volume above a medium in a first tank, the first CO2 concentration and the first pH value being measured at a first time when the medium in the first tank is in pH-CO2 equilibrium state with the first gas volume and before said equilibrium state is modified by the metabolism of a cell culture in the first tank, the first pH value being a measured value provided by a first pH measuring device operatively coupled to the first tank (102); receiving a second CO2 concentration and a second pH value, the second CO2 concentration being a CO2 concentration of a second gas volume above a medium in a second tank, the second CO2 concentration and the second pH value being measured

Abstract: Composite proton exchange membranes are described. The composite proton-exchange membranes comprise three layers including a proton exchange membrane layer, a continuous nonporous organic-inorganic composite coating layer, and a continuous nonporous cross-linked polyelectrolyte multilayer coating. Catalyst coated membranes incorporating the composite proton exchange membranes and methods of making the composite proton exchange membranes are also described.

Abstract: The electrolyte analysis test strip of the present invention includes a substrate extending in one direction. A first ion-sensitive film provided in a specific region on the one end side in the one direction and a first extraction electrode extending from the first ion-sensitive film to the other end side are provided on one main surface of the substrate. A second ion-sensitive film provided in a specific region on the one end side and a second extraction electrode extending from the second ion-sensitive film to the other end side are provided on the other main surface of the substrate. The first ion-sensitive film and the second ion-sensitive film each come into contact with an electrolyte to generate a first potential corresponding to a concentration of a first ion species and a second potential corresponding to a concentration of a second ion species, respectively.

Abstract: A method of sensing a target material in an environment is disclosed. The method comprises exposing a sensor to an environment for a first exposure period. The method further comprises, following the first exposure period, isolating the sensor from any target material in the environment for a first isolation period wherein the first isolation period is less than a characteristic recovery period for the sensor to return to a baseline after the first exposure period. The method further comprises, following the first isolation period, exposing the sensor to the environment for a second exposure period, and determining a concentration of the target material from a response of the sensor during the second exposure or a response of the sensor during the first and second exposure.

Abstract: The invention relates to a method for operating a fluidic microsystem (100) for the dielectrophoretic manipulation of suspended particles (1) having a particle diameter in a suspension liquid (2), wherein the microsystem (100) comprises: —a channel (10) having a longitudinal direction; —an electrode device (20) having an electrode (21), the longitudinal extent of which deviates from the longitudinal direction of the channel (10) and which has individually controllable electrode segments (22) for producing dielectrophoretic forces which act on the particles (1), each electrode segment (22) having a deflection angle ?, relative to the longitudinal direction of the channel (10), and a segment length (si), which determine a segment offset (Di) perpendicular to the longitudinal direction of the channel (10); and —a control device (30).

Abstract: A signal is obtained which comprises voltage measurements obtained from the calibration fluid and voltage measurements obtained from the unknown fluid. Diffusion of the measurements during the transition from measuring the calibration fluid to measuring the unknown fluid is modelled using a first model. The drift of the measurements is modelled from the calibration fluid measurements using a second model. The first model identifies a value and corresponding time point at which the diffusion process has settled. A calibration voltage value is estimated at the corresponding time point and the difference between the identified value and the calibration electrical potential value is calculated to determine a voltage difference. This voltage difference is normalized by adjusting the difference by a shift amount determined in relation to the calibration electrical potential value and a predetermined voltage value. The normalized voltage is then used to determine the ion concentration of the unknown fluid.

Abstract: A pattern electrode structure for an electrowetting device is laminated between a base material and a dielectric layer of the electrowetting device, and the pattern electrode structure includes first branch electrodes formed in a direction perpendicular to any plane perpendicular to a plane defined by the pattern electrode structure, and a basal pattern electrode formed in an area below lower ends of the first branch electrodes and connected to an electrode connection portion configured to receive a voltage, in which a sum of an interval between the first branch electrode and the basal pattern electrode and a width of the basal pattern electrode is larger than a diameter of a droplet to be removed, thereby preventing the droplet from stagnating without falling at the terminal end of the pattern in a structure that uses the vertical pattern.

Abstract: The present disclosure provides a sensing assembly for sensing an analyte. The sensing assembly comprises multiple test electrodes configured to provide signals from multiple independent measurements in response to the analyte. Alternatively or additionally, the multiple test electrodes are configured to produce different transient responses in response to a given concentration of the analyte.

Abstract: A method for recovering a biological substance and a device for recovering a biological substance capable of improving a recovery rate of a target biological substance with a simple configuration are provided. The method for recovering a biological substance uses an electrophoresis device having a gel 13 and recovery holes 11 and 111. The method for recovering a biological substance includes a step of starting application of a voltage for moving a target biological substance toward the recovery hole, after that, a step of removing buffer solution in the recovery hole before the target biological substance reaches the recovery hole, after that, a step of injecting a solvent into the recovery hole, and, after that, a step of recovering the target biological substance that reaches the recovery hole.

Abstract: A carbon monoxide gas sensor is a single-chamber sensor for measuring the carbon monoxide gas concentration in a gas phase. The carbon monoxide gas sensor has electrodes disposed on respective sides of a solid electrolyte layer. One of the electrodes is active for oxidation of carbon monoxide gas, and the other of the electrodes is more inactive for oxidation of carbon monoxide gas than the one electrode. The carbon monoxide gas sensor is configured to measure a short-circuit current between the electrodes. In the carbon monoxide gas sensor, the solid electrolyte layer has oxide ion conductivity.

Abstract: Embodiments relate to a biosensor. The biosensor includes an electrochemical system having a generator electrode, a collector electrode, and electrolyte. The generator electrode includes a particle capture region having an aspect ratio that is greater than 1. The particle capture region is a portion of the generator electrode configured to attract a particle supported within the electrolyte. The electrochemical system is operated so as to bias one of the generator electrode or the collector electrode below its formal potential while biasing the other electrode above its formal potential. The biosensor includes a processing module configured to measure electric current generated by the electrochemical system.

Abstract: The present disclosure provides sensor assemblies comprising a plurality of mixing species provided adjacent or on the sensing surface, wherein each mixing species comprises a polynucleotide chain and wherein each mixing species is anchored to the sensor assembly; and an actuation unit configured to move at least a part of each mixing species in a plurality of directions. Alternatively or additionally, the polynucleotide chain comprises DNA and has a length of at least 10 nm.

Abstract: A sensor includes: a support substrate; at least one surface structure protruding from an upper surface of the support substrate, wherein the surface structure includes an electrode layer; a sensing surface on the electrode layer, wherein the sensing surface is adapted to contact a sample containing a target analyte; a binding region on the support substrate, wherein the binding region is separated from the sensing surface; wherein, in use, a binding agent attached to a binding layer at the binding region is also adapted to contact the sample containing the target analyte.

Abstract: Some embodiments described herein relate to capillary-containing cartridges suitable for use with capillary electrophoresis instruments. Embodiments described herein generally relate to cartridges that include a transfer capillary coupled to a separation capillary. The transfer capillary can be configured to be disposed in sample reservoirs and/or buffer reservoirs. Suction applied through a sheath interface of the transfer capillary and the separation capillary can draw sample/buffer from such reservoirs and bring the sample/buffer into contact with the separation capillary. The separation capillary can be configured for separation of analytes contained within the sample, for example when an electric potential (i.e., voltage) is applied across the separation capillary.

Abstract: Provided are a sample analysis method comprising: separating hemoglobin in a sample from the sample comprising the hemoglobin, in an alkaline solution by capillary electrophoresis, wherein the alkaline solution comprises a cationic polymer having a secondary amino group and a quaternary ammonium base.

Abstract: A dopamine (DA) sensor includes a glassy carbon electrode including an indium oxide doped zinc oxide (In2O3-doped ZnO) decorated mesoporous carbon (In2O3·ZnO@MC) nanocomposite material. The In2O3·ZnO@MC includes aggregates of spherical In2O3 nanoparticles (NPs) and cubic ZnO NPs dispersed on the surface of the mesoporous carbon.

Abstract: An electrochemical sensor comprising an array of working electrodes made of noble metals, wherein the array includes: one or more bare working electrode(s); and a first set of working electrodes coated with a first transition metal dichalcogenide, the first set comprises at least subset A and subset B, wherein working electrodes of subset B show the presence of hydroxide form(s) and/or high oxidation state oxide forms(s) of the noble metal, whereas working electrodes of subset A are free of such forms; and/or working electrodes of subset B show higher capacitive currents and lower charge transfer resistance compared to working electrodes of subset A, as determined by electrochemical impedance spectroscopy.