Abstract: A sensor device is provided for the detection of an occurrence and/or a concentration and/or an amount of an analyte in a sample. The device includes a sensor, connection electronics and a housing. The sensor is configured to convert chemical and/or biochemical information from an analyte, preferably a virus, in a sample to an electrical signal. The sensor includes a test cantilever having a base and a deformable part, where a receptor layer for selective uptake of the analyte has been applied at least atop the deformable part. The sensor further includes a reference cantilever having a base and a deformable part, where a reference layer for selective non-uptake of the analyte has been applied atop the deformable part.

Abstract: The invention relates to an electrochemical sensor having a porous diaphragm and an electrolyte formulation that comprises at least one solvent, at least one electrolyte from the group of alkali metal salts and at least one alkaline earth metal ion, and to an electrolyte formulation.

Abstract: A nanoelectronic device includes first and second nano electrodes, a nanogap defined by the first and second nano electrodes and separating the first and second nano electrodes, a solvent present in the nanogap and including a plurality of redox molecules, and a component configured as a disruptor of solvent atomic structures, the component forming a surface portion on a bulk portion within the device, the component being located at a predetermined distance away from the first and second nano electrodes.

Abstract: An electrophoresis tank with a splicing function and an electrophoresis device are provided. The electrophoresis tank mainly includes an electrophoresis tank body, a connecting frame, and multiple first wiring terminals arranged on the connecting frame, where the connecting frame includes a clamping boss and a clamping groove adapted to the clamping boss; the clamping boss and the clamping groove are configured to connect two adjacent electrophoresis tank bodies; and the first wiring terminals are configured to connect circuits between the two adjacent electrophoresis tank bodies.

Abstract: The present disclosure provides a software-based approach for detecting bubbles in a fluid channel of a sensor system. According to this approach, readings from sensors which measure chemical characteristics of a sample fluid (e.g. ion concentrations of the sample fluid) are analysed. Any anomalous readings can be detected and analysed to determine whether the anomalous readings may be caused by the presence of one or more bubbles in the fluid channel. This approach removes the need to include additional conductivity sensors in the sensor system to detect bubbles, thereby freeing up sensor electrode sites which may be used for other sensors (e.g. additional calcium ion sensors). Bubbles that are detected can be shifted, or removed from the fluid channel entirely, by pumping fluid into the fluid channel.

Abstract: A bioelectrochemical soil assessment method and system is disclosed, wherein electrical measurements provide distinct differences between healthy and unhealthy soils, and wherein the presence of microbes coupled to an electrode also indicates healthy soil but not for unhealthy soil. Moreover, a soil amendment solution addition stimulated current in both healthy and unhealthy soil, wherein the electrical current is utilized as a proxy for microbial metabolic activity to distinguish healthy and unhealthy soil.

Abstract: Provided is a novel mediator. The present invention relates to a novel mediator, and an electrode modifying agent and an electron transfer promoting agent comprising the mediator, an electrode, a battery, a composition, and an enzyme sensor comprising the electrode modifying agent or the electron transfer promoting agent, and a method using any of these.

Abstract: The present disclosure provides a biosensor platform for rapid detection of otolin-1 and prestin, blood-circulating proteins specifically expressed in the vestibule and cochlea, respectively. The platform is designed on a DNA-based immunoassay that employs conjugated antibodies for target protein recognition, which when bound, altered the DNA-DNA hybridization on the surface, resulting in generation of a concentration-dependent electrochemical output in whole blood. Signal amplification is acquired by employing high-curvature nanostructured electrodes for sensitive sample analysis at low picomolar concentrations with a three-fold quantitative range, in a 10-?L sample in 10 minutes. Using antibodies as recognition elements allows for the adaptation of this platform to detect any blood-circulating protein.

Abstract: In some embodiments, a method includes applying an analyte to a rGO biosensor configured to bind to the analyte; applying a DC voltage to the rGO biosensor, wherein the DC voltage is +0.0008 V to +0.005 V for a negatively charged analyte; or ?0.005 V to ?0.0008 for a positively charged analyte; and monitoring an electrical signal from the rGO biosensor for a response to the analyte.

Abstract: The present invention relates to a method for the preparation of a working electrode, the method comprising application of a sensing material in several steps. Further, the present invention relates to an analyte sensor comprising the working electrode as well as to the use of the analyte sensor for detecting at least one analyte in a sample.

Abstract: Provided are an electrolyte analysis device and a method for identifying an abnormality in the same that make it possible to detect an abnormality in an ion-selective electrode at an early stage. The electrolyte analysis device comprises an ion-selective electrode that generates a sample potential that is a potential corresponding to the ion concentration of a sample, a reference electrode that generates a reference potential that is a potential to serve as a reference, and a concentration calculation unit that calculates the ion concentration on the basis of the potential difference between the sample potential and the reference potential. The electrolyte analysis device is characterized by additionally comprising an abnormality determination unit for determining whether there is an abnormality on the basis of an evaluation value that has been calculated using a detergent potential that is a potential generated by the ion-selective electrode when a detergent was supplied.

Abstract: The present technology relates to improved device and methods of use of insulator-based dielectrophoresis. This device provides a multi-length scale element that provides enhanced resolution and separation. The device provides improved particle streamlines, trapping efficiency, and induces laterally similar environments. Also provided are methods of using the device.

Abstract: An electrochemical biosensor has an electrode which is sequentially decorated a molybdenum (VI) oxide (MoO3) nanomaterial, a gold-composite nanomaterial, a carboxyl-sulfhydryl compound, and a carbodiimide/N-hydroxysuccinimide (EDC/NHS, EN) to modify the surface of the electrode. That the sulfhydryl group of the carboxyl-sulfhydryl compound forms a bond with the gold-composite nanomaterial, and the carbodiimide/N-hydroxybutanediimide forms a bond with a carboxyl group of the carboxyl-sulfhydryl compound.

Abstract: The invention relates to a comparison unit (130) configured for determining if a first pH measuring device of a first tank (104; 106) is affected by a pH-measuring problem, the comparison unit being configured for: receiving a first CO2 concentration and a first pH value, the first CO2 concentration being a CO2 concentration of a first gas volume above a medium in a first tank, the first CO2 concentration and the first pH value being measured at a first time when the medium in the first tank is in pH-CO2 equilibrium state with the first gas volume and before said equilibrium state is modified by the metabolism of a cell culture in the first tank, the first pH value being a measured value provided by a first pH measuring device operatively coupled to the first tank (102); receiving a second CO2 concentration and a second pH value, the second CO2 concentration being a CO2 concentration of a second gas volume above a medium in a second tank, the second CO2 concentration and the second pH value being measured

Abstract: Composite proton exchange membranes are described. The composite proton-exchange membranes comprise three layers including a proton exchange membrane layer, a continuous nonporous organic-inorganic composite coating layer, and a continuous nonporous cross-linked polyelectrolyte multilayer coating. Catalyst coated membranes incorporating the composite proton exchange membranes and methods of making the composite proton exchange membranes are also described.

Abstract: The electrolyte analysis test strip of the present invention includes a substrate extending in one direction. A first ion-sensitive film provided in a specific region on the one end side in the one direction and a first extraction electrode extending from the first ion-sensitive film to the other end side are provided on one main surface of the substrate. A second ion-sensitive film provided in a specific region on the one end side and a second extraction electrode extending from the second ion-sensitive film to the other end side are provided on the other main surface of the substrate. The first ion-sensitive film and the second ion-sensitive film each come into contact with an electrolyte to generate a first potential corresponding to a concentration of a first ion species and a second potential corresponding to a concentration of a second ion species, respectively.

Abstract: A method of sensing a target material in an environment is disclosed. The method comprises exposing a sensor to an environment for a first exposure period. The method further comprises, following the first exposure period, isolating the sensor from any target material in the environment for a first isolation period wherein the first isolation period is less than a characteristic recovery period for the sensor to return to a baseline after the first exposure period. The method further comprises, following the first isolation period, exposing the sensor to the environment for a second exposure period, and determining a concentration of the target material from a response of the sensor during the second exposure or a response of the sensor during the first and second exposure.

Abstract: The invention relates to a method for operating a fluidic microsystem (100) for the dielectrophoretic manipulation of suspended particles (1) having a particle diameter in a suspension liquid (2), wherein the microsystem (100) comprises: —a channel (10) having a longitudinal direction; —an electrode device (20) having an electrode (21), the longitudinal extent of which deviates from the longitudinal direction of the channel (10) and which has individually controllable electrode segments (22) for producing dielectrophoretic forces which act on the particles (1), each electrode segment (22) having a deflection angle ?, relative to the longitudinal direction of the channel (10), and a segment length (si), which determine a segment offset (Di) perpendicular to the longitudinal direction of the channel (10); and —a control device (30).

Abstract: A signal is obtained which comprises voltage measurements obtained from the calibration fluid and voltage measurements obtained from the unknown fluid. Diffusion of the measurements during the transition from measuring the calibration fluid to measuring the unknown fluid is modelled using a first model. The drift of the measurements is modelled from the calibration fluid measurements using a second model. The first model identifies a value and corresponding time point at which the diffusion process has settled. A calibration voltage value is estimated at the corresponding time point and the difference between the identified value and the calibration electrical potential value is calculated to determine a voltage difference. This voltage difference is normalized by adjusting the difference by a shift amount determined in relation to the calibration electrical potential value and a predetermined voltage value. The normalized voltage is then used to determine the ion concentration of the unknown fluid.

Abstract: A pattern electrode structure for an electrowetting device is laminated between a base material and a dielectric layer of the electrowetting device, and the pattern electrode structure includes first branch electrodes formed in a direction perpendicular to any plane perpendicular to a plane defined by the pattern electrode structure, and a basal pattern electrode formed in an area below lower ends of the first branch electrodes and connected to an electrode connection portion configured to receive a voltage, in which a sum of an interval between the first branch electrode and the basal pattern electrode and a width of the basal pattern electrode is larger than a diameter of a droplet to be removed, thereby preventing the droplet from stagnating without falling at the terminal end of the pattern in a structure that uses the vertical pattern.