Patents Examined by C. Yu
  • Patent number: 8821838
    Abstract: The present invention provides a trialkoxysilane having structure I wherein R1 is independently at each occurrence a C1-C3 alkyl group; R3 is independently at each occurrence a hydrogen or a C1-C3 alkyl group; R4 is a C1-C5 aliphatic radical, a C7-C12 aromatic radical, or a C5-C10 cycloaliphatic group; n is 0, 1, 2 or 3; q is 1, 2 or 3; t is 0, 1 or 2; and X? represents a charge balancing counterion. The trialkoxysilanes are useful for the preparation of nanoparticulate diagnostic imaging agent compositions.
    Type: Grant
    Filed: August 23, 2012
    Date of Patent: September 2, 2014
    Assignee: General Electric Company
    Inventors: Peter John Bonitatibus, Jr., Matthew David Butts, Robert Edgar Colborn, Andrew Soliz Torres
  • Patent number: 8753655
    Abstract: The present invention generally relates to the field of membranes. In particular, the present invention relates to a composition comprising bodies surrounded by a membrane. The composition are for example edible compositions. One embodiment of the present invention relates to a composition containing an oily fraction, a hydrophilic fraction, and at least one body, wherein the body comprises a shell comprising several molecular layers of chitosan and at least one lipidic phosphatidic acid surfactant; and a content comprising an internal phase containing a hydrophilic component and/or a hydrophobic component. The Composition may be used to protect a food product or to deliver specific properties to a product, for example.
    Type: Grant
    Filed: February 17, 2011
    Date of Patent: June 17, 2014
    Assignee: Nestec S.A.
    Inventors: Zeynel Deniz Gunes, Matthieu Pouzot, Raffaele Mezzenga, David Labbe
  • Patent number: 8313735
    Abstract: A method of making-up a keratinous substrate involving: (a) providing a keratinous substrate; (b) applying a basecoat composition onto the keratinous substrate, the basecoat composition comprising: (i) at least one silicone-polyamide copolymer; (ii) at least one silicone film former; (iii) at least one volatile oil; and (iv) at least one colorant; and (c) applying a topcoat composition over top of the basecoat composition, the topcoat composition comprising: (i) at least one tackifier component having a solubility parameter corresponding to ?; (ii) at least one block copolymer having at least one hard segment and at least one soft segment and wherein at least one of said hard and/or soft segments has a solubility parameter corresponding to ?±2; (iii) at least one solvent; and (iv) optionally, at least one colorant.
    Type: Grant
    Filed: October 30, 2006
    Date of Patent: November 20, 2012
    Inventor: Padraig McDermott
  • Patent number: 8299106
    Abstract: The present invention relates to novel thiazole-substituted indolin-2-ones as inhibitors of CSCPK and related kinases; to methods of inhibiting cancer stem cells by using a kinase inhibitor; to pharmaceutical compositions containing such compounds; and to methods of using such compounds in the treatment of a protein kinase related disorder in a mammal; and to processes of making such compounds and intermediates thereof.
    Type: Grant
    Filed: September 5, 2008
    Date of Patent: October 30, 2012
    Assignee: Boston Biomedical, Inc.
    Inventors: Chiang Jia Li, Ji-Feng Liu, Youzhi Li, Wei Li, Harry Rogoff
  • Patent number: 8293279
    Abstract: The present invention relates to polyamide powders suitable for cosmetic applications are described which have a pH of 4.0 to 7.0, cosmetic compositions containing the polyamide powders and processes of making the same.
    Type: Grant
    Filed: July 15, 2008
    Date of Patent: October 23, 2012
    Assignee: Evonik Degussa GmbH
    Inventors: Thomas Schiffer, Holger Renners, Wolfgang Christoph, Franz-Erich Baumann, Joachim Muegge
  • Patent number: 8287899
    Abstract: The invention relates to a patch for cutaneous application of a substance, the patch comprising a substance designed to penetrate the epidermis, means for placing the substance in contact with the skin and a peelable cutaneous exfoliation film enabling exfoliation of the skin, after placing the patch, at the level of the contact zone between said substance and the skin.
    Type: Grant
    Filed: February 15, 2008
    Date of Patent: October 16, 2012
    Assignee: DBV Technologies
    Inventor: Bertrand Dupont
  • Patent number: 8273373
    Abstract: A photocrosslinked biodegradable hydrogel includes a plurality of natural polymer macromers cross-linked with a plurality of hydrolyzable acrylate cross-links. The hydrogel is cytocompatible and produces substantially non-toxic products upon degradation.
    Type: Grant
    Filed: December 30, 2009
    Date of Patent: September 25, 2012
    Assignee: Case Western Reserve University
    Inventors: Eben Alsberg, Oju Jeon
  • Patent number: 8263666
    Abstract: Composition for topical application in the form of an oil-in-water emulsion containing an oily phase dispersed in an aqueous phase, and a hydrophilic polymer, the composition further containing (1) at least one elastomeric organopolysiloxane and (2) at least one lipophilic compound chosen from lipophilic amino acid compounds and lipophilic salicylic acid compounds. Uses thereof, including topical application to the skin, lips, hair, etc. Stabilization of certain emulsions using a lipophilic compound.
    Type: Grant
    Filed: October 16, 2003
    Date of Patent: September 11, 2012
    Assignee: L'Oreal
    Inventors: Christine Noel, Anne-France Livernette
  • Patent number: 8263096
    Abstract: Bodywash compositions incorporating high levels of emollient oils and a method for incorporating such high levels of emollient into bodywash compositions.
    Type: Grant
    Filed: September 15, 2011
    Date of Patent: September 11, 2012
    Assignee: The Dial Corporation
    Inventor: E. Gary Myers
  • Patent number: 8263117
    Abstract: A solution containing a C70 cyclodextrin complex and a solution containing a lipid that is capable of forming a liposome are mixed together at a temperature in a range of 10° C. to 45° C. This produces a C70-incorporated liposome which keeps a physical property that the C70 fullerene originally has, and is stably solubilized in a polar solvent. Hence, the present invention provides a C70-incorporated liposome which keeps a physical property that the C70 fullerene originally has, and which is stably solubilized in a polar solvent, a production method of the same, and a use of the same.
    Type: Grant
    Filed: February 6, 2008
    Date of Patent: September 11, 2012
    Assignee: National University Corporation Nara Institute of Science and Technology
    Inventors: Atsushi Ikeda, Jun-ichi Kikuchi
  • Patent number: 8258191
    Abstract: A topical skin barrier for protecting and promoting healing of skin, and for providing comfort to a patient, comprises a semi-solid hydrocarbon and a water-absorbing compound. The topical skin barrier effectively adheres to skin, affords protection from moisture and waste, and provides transparency in use. Methods of in vitro evaluation are for (i) a composition's protection from moisture and waste, and (ii) a composition's adhesion to skin.
    Type: Grant
    Filed: October 31, 2005
    Date of Patent: September 4, 2012
    Assignee: Coloplast A/S
    Inventors: Donald L. Gerrish, Kevin C. Tauer
  • Patent number: 8247435
    Abstract: The present disclosure provides for a scientific formulation useful in the treatment and prevention of human and animal diseases. A biologically effective amount of each of the components of the formulation is administered to patients in pill (or capsule) form via multiple different and identifiable pills. The compounds of the formulation are segregated into different pill types, and contain various amounts of the compounds Curcumin, Genistein, Squalamine, Vitamin E, N-Acetyl-Cysteine, Methylselenocysteine, Zinc Gluconate, B Complex, Lentinen, Coenzyme Q10 Acetyl-L-Carnitine, Lipoic Acid, Resveratrol, and Vitamin C. Furthermore, Arabinoxylan and/or Peperine may be added to the various pill formulations.
    Type: Grant
    Filed: February 19, 2009
    Date of Patent: August 21, 2012
    Inventor: Jerry T. Thornthwaite
  • Patent number: 8246997
    Abstract: The present invention relates to topical compositions containing solid particles that are stabilized via encapsulation into a cross-linked silicone matrix. The solid particles are preferably formed of a metal oxide, such as zinc oxide or titanium dioxide, and the cross-linked silicone matrix is preferably formed by cross-linking a silicone having branched reactive alkoxyl moieties in the presence of a stannous carboxylate cross-linking agent. The stabilized particles of the present invention can readily be used either alone or in combination with other skin care actives to form topical compositions with improved stability and performance.
    Type: Grant
    Filed: August 10, 2009
    Date of Patent: August 21, 2012
    Assignee: ELC Management LLC
    Inventor: Wilson Lee
  • Patent number: 8236781
    Abstract: The present invention relates to a hydrogel of chitosan carboxyalkylamide, characterised in that it has a pH value close to that of the skin, comprised between 6.5 and 7.2, and in that the chitosan carboxy-alkylamide is constituted by 40 to 90 mole % of D-glucosamine N-carboxyalkylamide units of formula (I) where n represents an integer ranging from 1 to 8, from 60 to 10 mole % of protonated D-glucosamine units, and from 5 to 15 mole % of N-acetyl-D-glucosamine units. The present invention also relates to a dehydration product of such a gel and the cosmetic and/or dermatological utilisation of the gel and the dehydration product.
    Type: Grant
    Filed: July 1, 2008
    Date of Patent: August 7, 2012
    Inventors: Elisabeth Laugier, Franck Gouchet, Jean-Pierre Perraud
  • Patent number: 8221766
    Abstract: The present invention describes compositions and methods for treating, preventing and improving the appearance of skin, particularly, treating, preventing, ameliorating, reducing and/or eliminating skin irritation, inflammation, and/or the signs of visible or subjective discomfort, wherein the compositions include natural plant constituents that inhibit at least one cytokine. The plant extracts are preferably derived from Populus nigra, Rhinacanthus nasutus, Sapindus rarak, and Thumbergia laurifolia, and any combinations thereof. The compositions are preferably applied to the skin, or are delivered by directed means, to a site in need thereof.
    Type: Grant
    Filed: December 22, 2004
    Date of Patent: July 17, 2012
    Assignee: Avon Products, Inc.
    Inventors: Laurence Dryer, Dmitri Ptchelintsev
  • Patent number: 8216596
    Abstract: Disclosed are stabilized body care products, household products, textiles and fabrics which comprise certain sterically hindered amine salt compounds. Dyed products and articles are effectively stabilized against color degradation. The products are for example skin-care products, hair-care products, dentifrices, cosmetics, laundry detergents and fabric softeners, non-detergent based fabric care products, household cleaners and textile-care products.
    Type: Grant
    Filed: May 11, 2006
    Date of Patent: July 10, 2012
    Assignee: BASF SE
    Inventors: Joseph A. Lupia, Joseph Suhadolnik, Mervin G. Wood, Wanda H. Martin
  • Patent number: 8211871
    Abstract: A topical skin barrier for protecting and promoting healing of skin, and for providing comfort to a patient, comprises a semi-solid hydrocarbon, a water-absorbing compound, and a pain relief agent. The topical skin barrier effectively adheres to skin, affords protection from moisture and waste, provides transparency in use, and is anhydrous and therefore is preservative-free. Methods of in vitro evaluation are for (i) a composition's protection from moisture and waste, and (ii) a composition's adhesion to skin.
    Type: Grant
    Filed: April 28, 2006
    Date of Patent: July 3, 2012
    Assignee: Coloplast A/S
    Inventor: Donald L. Gerrish
  • Patent number: 8202242
    Abstract: A mammal undergoing an energy-based therapy is treated by administering at least one vasoconstrictive agent to the mammal prior to or during the procedure. The at least one vasoconstrictive agent is added in amounts sufficient to reduce or prevent vasodilation. This treatment method increases or promotes the size of the coagulation zone created after energy-based therapy.
    Type: Grant
    Filed: July 16, 2008
    Date of Patent: June 19, 2012
    Assignee: Covidien AG
    Inventor: Ronald J. Podhajsky
  • Patent number: 8202549
    Abstract: The present invention relates to hemostatic compositions comprising a mesocellular oxide foam and, optionally, a biologically active agent such as a procoagulant, as well as devices and methods of use to promote blood clotting.
    Type: Grant
    Filed: August 13, 2008
    Date of Patent: June 19, 2012
    Assignee: The Regents of the University of California
    Inventors: Galen Stucky, Sarah Baker, April Sawvel
  • Patent number: 8197833
    Abstract: The invention relates to a liquid concentrate for preserving cosmetic products which comprises a combination of carboxylic acid salts chosen from the salts of benzoic acid, propionic acid, salicylic acid, sorbic acid, 4-hydroxybenzoic acid, dehydracetic acid, formic acid or 10-undecylenic acid and alcohols chosen from 2-phenoxyethanol, benzyl alcohol, phenethyl alcohol, 1-phenoxypropan-2-ol, 3-(4-chlorophenoxy)-1,2-propanediol, chlorobutanol or 2,4-dichlorobenzyl alcohol in a solvent, where the active ingredient content is greater than 45% by weight.
    Type: Grant
    Filed: January 13, 2009
    Date of Patent: June 12, 2012
    Assignee: Air Liquide Sante (International)
    Inventors: Wolfgang Beilfuss, Gisela Hahn, Klaus Weber, Ralf Gradke