Patents Examined by Catherine S. Kirby Scalzo
  • Patent number: 5312823
    Abstract: The invention relates to new quinolonecarboxylic acid derivatives which are substituted in the 7-position by an optionally partially hydrogenated azaisoindolinyl ring, to processes for their preparation, and to antibacterial agents and feed additives containing them.
    Type: Grant
    Filed: June 19, 1992
    Date of Patent: May 17, 1994
    Assignee: Bayer Aktiengesellschaft
    Inventors: Uwe Petersen, Andreas Krebs, Thomas Schenke, Klaus Grohe, Klaus-Dieter Bremm, Rainer Endermann, Karl-Georg Metzger, Hans-Joachim Zeiler
  • Patent number: 5196438
    Abstract: Compounds having the formula ##STR1## wherein R is benzyloxycarbonyl or 2-quinolylcarbonyl, and their pharmaceutically acceptable acid addition salts inhibit proteases of viral origin and can be used as medicaments for the treatment of prophylaxis of viral infections in mammals, humans or non-humans.
    Type: Grant
    Filed: November 19, 1990
    Date of Patent: March 23, 1993
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Joseph A. Martin, Sally Redshaw
  • Patent number: 5006664
    Abstract: Novel aminoalkylthiodibenzothiepins and related compounds, physiologically tolerable acid addition salts thereof, a method of preparing same, pharmaceutical and veterinary preparations including same and methods of treating by administering same are disclosed. These compounds are useful as antidepressant, analgetic, and anticonvulsant agents.
    Type: Grant
    Filed: December 20, 1989
    Date of Patent: April 9, 1991
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Helen H. Ong, Vernon B. Anderson, James A. Profitt
  • Patent number: 4925664
    Abstract: Methods and compositions for blocking various channels and receptors within an organism are provided. For example, two toxins were isolated from the Agelenopsis aperta spider. The first toxin comprised a toxin having a molecular weight of from approximately 5,000 to approximately 10,000. This toxin was found to have an irreversible effect on calcium channels within the central nervous system. A second toxin having a molecular weight of less than about 1,000 was also isolated. This toxin was found to have a reversible blocking effect on calcium channels within the central nervous system and the cardiovascular system.A third toxin was isolated from the Argiope aurantia spider. This toxin was found to have a reversible effect on excitatory amino acid receptors. Finally, a toxin having a molecular weight of from approximately 5,000 to approximately 7,000 daltons was isolated from the Hololena Curta spider. This toxin was found to have an irreversible effect on excitatory amino acid receptors.
    Type: Grant
    Filed: October 20, 1986
    Date of Patent: May 15, 1990
    Assignee: University of Utah
    Inventors: J. R. Hunter Jackson, Thomas N. Parks