Patents Examined by Cecilia M. S. Jaisle
  • Patent number: 4116977
    Abstract: An oxygen-containing cyclicfluoro compound selected from the group consisting of a perfluorolactone having the formula ##STR1## a perfluorocyclic ether having the formula ##STR2## and mixtures thereof is produced by reacting an .alpha.,.omega.-diiodoperfluoroalkane having the formulaI (CF.sub.2).sub.n Iwith fuming sulfuric acid, wherein n is all formulas ranges from 3 to 5.
    Type: Grant
    Filed: August 5, 1976
    Date of Patent: September 26, 1978
    Assignee: Asahi Glass Company Ltd.
    Inventors: Masaaki Yamabe, Kiyotaka Arai, Shunichi Samejima, Makoto Noshiro
  • Patent number: 4104398
    Abstract: The levorotatory enantiomers of 3-loweralkoxy-cyproheptadines are potent antiserotonin agents with a lower order of antihistaminic activity and substantially free of any anticholinergic activity. They are prepared by treatment of the levorotatory enantiomer of 3-iodocyproheptadine with an alkali metal lower alkoxide in the presence of copper powder.
    Type: Grant
    Filed: August 12, 1976
    Date of Patent: August 1, 1978
    Assignee: Merck & Co., Inc.
    Inventor: David C. Remy
  • Patent number: 4104396
    Abstract: 2-Piperidinoalkyl-1,4-benzodioxans, e.g. those of the formula ##STR1## AND ACID ADDITION SALTS THEREOF ARE NEUROLEPTIC AGENTS.
    Type: Grant
    Filed: April 26, 1976
    Date of Patent: August 1, 1978
    Assignee: Ciba-Geigy Corporation
    Inventor: Charles Ferdinand Huebner
  • Patent number: 4089869
    Abstract: A perfluorolactone having the formula ##STR1## wherein n is an integer of 2 to 4, is produced by reacting a fluoro compound having the formulaI(CF.sub.2).sub.n COXwherein n is an integer of 2 to 4 and X represents a halogen atom, --OR or --NR.sup.1 R.sup.2, and R, R.sup.1 and R.sup.2 respectively represent hydrogen atom or a C.sub.1 - C.sub.10 alkyl group, with fuming sulfuric acid.
    Type: Grant
    Filed: September 10, 1976
    Date of Patent: May 16, 1978
    Assignee: Asahi Glass Company Ltd.
    Inventors: Masaaki Yamabe, Seiji Munekata, Seisaku Kumai, Shunichi Samejima
  • Patent number: 4087445
    Abstract: N-(5,7-Dibromo-1,3-benzoxathiol-2-ylidene)-N-methylmethanaminium bromide and the analogous diodo iodide, new compounds, are prepared by the thermal rearrangement of O-(2,4,6-tribromophenyl)-N,N-dimethylthiocarbamate and O-(2,4,6-triiodophenyl)-N,N-dimethylthiocarbamate. The first-named compound has antimicrobial utility. Both compounds are useful as starting materials for the preparation of bis-(3,5-dibromo-2-hydroxyphenyl)disulfide and 2,4-diiodo-6-mercaptophenol, respectively, by hydrolysis of the two first-named compounds with methanolic sodium hydroxide. Both the disulfide and the mercaptophenol compounds have antimicrobial utility.
    Type: Grant
    Filed: March 24, 1977
    Date of Patent: May 2, 1978
    Assignee: The Dow Chemical Company
    Inventors: Charles E. Reineke, Christian T. Goralski
  • Patent number: 4086255
    Abstract: Phenyl-substituted perfluoroalkanesulfonanilides in which the phenyl rings are linked by sulfur, sulfinyl or sulfonyl and salts thereof in which the rings and the perfluoroalkylsulfonamido nitrogen are optionally substituted. The compounds are active herbicides and some are anti-inflammatory agents and analgesic agents.
    Type: Grant
    Filed: January 10, 1977
    Date of Patent: April 25, 1978
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: George G. I. Moore, Joseph Kenneth Harrington
  • Patent number: 4084954
    Abstract: 1,3-Benzodithiole-2-one and 1,3-benzodithiole-2-thione compounds are disclosed including the novel method of preparing said compounds and their biocidal activity.
    Type: Grant
    Filed: September 30, 1975
    Date of Patent: April 18, 1978
    Assignee: The Ansul Company
    Inventors: Khalid Rasheed, James D. Warkentin
  • Patent number: 4083855
    Abstract: A method for producing a 3,3-dimethyl-4-(2,2-dihalogenovinyl)-4-hydroxybutyric-1,4-lactone of the formula, ##STR1## wherein X is a halogen atom, which comprises reacting a 1,1,1-trihalogeno-4-methyl-3-pentene-2-ol of the formula, ##STR2## wherein X is a halogen atom, or a 1,1,1-trihalogeno-4-methyl-4-pentene-2-ol of the formula, ##STR3## wherein X is a halogen atom, or the mixture of the both compounds with vinylidene chloride of the formula, ##STR4## IN SULFURIC ACID.
    Type: Grant
    Filed: February 4, 1977
    Date of Patent: April 11, 1978
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Nobushige Itaya, Fumio Fujita
  • Patent number: 4083852
    Abstract: 16-Oxa- and 16-thia-D-homo-estrogen derivatives useful as postcoital oral contraceptives which are produced by total synthesis from 1-vinyltetralin-1-ols or their thiuronium derivatives on reactions with 4-substituted tetrahydropyran- or tetrahydrothiopyran-3,5-diones, and subsequent appropriate modifications.
    Type: Grant
    Filed: November 5, 1976
    Date of Patent: April 11, 1978
    Assignee: Shionogi & Co., Ltd.
    Inventors: Tadao Terasawa, Toshihiko Okada
  • Patent number: 4082769
    Abstract: Treating compounds of the formula ##STR1## in which the nuclei marked "A" and "B" can be substituted by halogen, lower alkyl, lower alkoxy or phenyl, with acid binding agents at elevated temperatures in polar organic solvents yields compounds of the formula ##STR2## in which A and B have the same meaning. The products are dyestuffs of high brillancy, pure shades, high fluorescence, excellent tinctorial strength and good fastness to light.
    Type: Grant
    Filed: February 25, 1977
    Date of Patent: April 4, 1978
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Otto Fuchs, Helmut Troster
  • Patent number: 4080332
    Abstract: There are described novel charge transfer compounds having high electrical conductivity which are represented by the formula [A].sub.x.sup.+ [B].sub.y.sup.- where A is represented by the formula ##STR1## where R.sub.1 -R.sub.4 may be the same or different and may be H or CH.sub.3 and B is 7,7,8,8-tetracyanoquinodimethane, X is 1 and Y is 1 or 2.
    Type: Grant
    Filed: June 28, 1976
    Date of Patent: March 21, 1978
    Assignee: Xerox Corporation
    Inventors: Daniel J. Sandman, Arthur J. Epstein
  • Patent number: 4079140
    Abstract: Compounds having the formula ##STR1## wherein R.sub.1 and R.sub.2 are alkyls or alkenyls having 1 to 4 atoms or ##STR2## is pyrrolidino, piperidino, perhydroazepino or morpholino, and RX is a salt-forming moiety. The compounds are prepared by reacting 2-acetyl benzothiophene with ##STR3## The compounds possess a blood plaque aggregation inhibiting property and also possess spasmolytic, analgesic, anti-inflammatory and coronary, cerebral and peripheral vasodilatatory properties.
    Type: Grant
    Filed: March 31, 1976
    Date of Patent: March 14, 1978
    Assignee: Innothera
    Inventors: Max Fernand Robba, Michel Aurousseau
  • Patent number: 4079141
    Abstract: Novel substituted azabicycloalkanes and methods of preparing the same are disclosed. These compounds are useful as analgetic agents which exhibit a tendency towards low physical dependence.
    Type: Grant
    Filed: October 14, 1976
    Date of Patent: March 14, 1978
    Assignee: American Hoechst Corporation
    Inventors: Helen Hu Ong, Vernon Brian Anderson
  • Patent number: 4078072
    Abstract: Novel N-tricyclic derivatives of azetidine are disclosed of the general formula: ##STR1## WHERE A is a --CH.sub.2 --S-- or --S--CH.sub.2 -- group, the remaining substituents being defined in the specification. Illustrative is the compound 1-[11-(6,11-dihydro-dibenzo [b,e] thiopinyl)]-3-methylamino-azetidine. The compounds are useful for their anti-depressant, anti-convulsant and anxiolytic activities.
    Type: Grant
    Filed: November 2, 1976
    Date of Patent: March 7, 1978
    Assignee: Carlo Erba S.p.A.
    Inventors: Piero Melloni, Arturo Della Torre, Francesco Lauria, Norina Passerini, Alessandro Rossi, Raffaele Tommasini
  • Patent number: 4076720
    Abstract: 1-Substituted-2-(2-pyridinyl)ethanone N-oxides having the formula I or II: ##STR1## wherein R.sub.1 is hydrogen or lower alkyl; R.sub.2 and R.sub.3 are each hydrogen, halogen, hydroxy, lower alkyl, lower alkoxy, or benzyloxy; R.sub.4 is halogen, hydroxy, lower alkyl, lower alkoxy, benzyloxy, ortho-amino, ortho-lower alkylamino, ortho-alkanoylamino or ortho-benzoylamino; and R.sub.5 is hydrogen, halogen, hydroxy, lower alkyl, lower alkoxy or benzyloxy; the pharmaceutically acceptable acid addition salts thereof, and a process for the preparation thereof, are described. The compounds of this invention are useful for the treatment of allergic conditions and for the treatment of hyperacidity.This is a division of application Ser. No. 611,282 filed Sept. 8, 1975.
    Type: Grant
    Filed: January 25, 1977
    Date of Patent: February 28, 1978
    Assignee: Warner-Lambert Company
    Inventors: David T. Connor, Patricia A. Young, Maximilian VON Strandtmann
  • Patent number: 4075346
    Abstract: Novel compounds of the formula: ##STR1## wherein R is a hydrogen or fluorine atom, W is an oxygen atom or an ethylenedioxy or ethylenedithio group and Z is a certain secondary amino group, which are useful as central nervous system depressants, can be prepared by the reaction of a compound of the formula: ##STR2## wherein X is a halogen atom and R and W are each as defined above with a secondary amine of the formula: H--Z wherein Z is as defined above, in case of W being ethylenedioxy or ethylenedithio, optionally followed by hydrolysis and can be reduced to give a compound of the formula: ##STR3## wherein R and Z are each as defined above, which are useful as antipsychotic and/or analgesic agents.
    Type: Grant
    Filed: July 16, 1976
    Date of Patent: February 21, 1978
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Kikuo Sasajima, Keiichi Ono, Yasuo Motoike, Shigeho Inaba, Hisao Yamamoto
  • Patent number: 4075226
    Abstract: Decahydro-3,3,8,8-tetramethoxy-2,7-epithio-1,4-ethanonaphthalene-5,9-dione, decahydro-3,3,8,8-tetraethoxy-2,7-epithio-1,4-ethanonaphthalene-5,9-dione, decahydro-dispiro[1,3-dioxolane-2,3'-(2',7'-epithio-1',4'-ethanonaphthalen e)-8',2"-[1,3]dioxolane]-5',9'-dione have been found to be effective as secondary antioxidants for polyolefins.
    Type: Grant
    Filed: March 11, 1977
    Date of Patent: February 21, 1978
    Assignee: Eastman Kodak Company
    Inventor: Charles H. Foster
  • Patent number: 4075227
    Abstract: Derivatives of 2-aroyl-3-phenylbenzothiophenes and 2-aroyl-3-phenylbenzothiophene-1-oxides are useful as antifertility agents.
    Type: Grant
    Filed: November 22, 1976
    Date of Patent: February 21, 1978
    Assignee: Eli Lilly and Company
    Inventors: C. David Jones, Tulio Suarez
  • Patent number: 4073797
    Abstract: A novel class of dithiane and disulfone compound is described. These compounds are pharmaceutically active as coronary dilating agents and thus can be used therapeutically in cases of insufficient cardiac blood supply, i.e., in the treatment of angina pectoris. A preferred compound is N-(3,4-dimethoxyphenethyl)-2-(3,4-dimethoxyphenyl)-N-methyl-m-dithiane-2-p ropylamine-1,1-3,3-tetraoxide.
    Type: Grant
    Filed: October 1, 1976
    Date of Patent: February 14, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Henri Ramuz
  • Patent number: 4073930
    Abstract: 2-Oximino-1,3,5-trithiane compounds are useful intermediates in the preparation of 1,3,5-trithiane carbamoyloxime compounds which exhibit outstanding pesticidal activity.
    Type: Grant
    Filed: June 1, 1976
    Date of Patent: February 14, 1978
    Assignee: Union Carbide Corporation
    Inventors: Arthur P. Kurtz, Jr., Themistocles D. J. D'Silva