Abstract: The multiple allergen testing system includes an applicator and a fluid tray. The fluid tray is cooperatively engageable with the applicator. The applicator has an allergen loading position and an allergen deposition position. In the allergen loading position, a different allergen is loaded onto each respective scratching barb from each respective reservoir of the loading tray. Each scratching barb is designed to retain a trace of allergen fluid. A pair of finger grips are positioned on opposing sides of the applicator frame. The applicator fits into one hand of a medical technician administering the allergen skin testing. The applicator is removed from the fluid tray and repositioned onto the skin of the patient. The applicator is made of compressible material. In the allergen deposition position, the applicator is compressed, and each allergen is deposited into each respective scratch generated by each respective scratching barb on the skin for further analysis.

Abstract: One embodiment of an exemplary ambulatory seizure monitoring method calculates a phase lock value synchrony level of a neurological signal of an individual; detects an onset of a seizure event for the individual by comparing the phase lock value synchrony level with a patient threshold for the individual; and transmits a notification to a remote communication device indicating the onset of the seizure event for the individual.

Abstract: The present invention provides a circuit applied to a bio-information acquisition system, wherein the circuit includes a terminal, an output circuit, a feedback circuit and a calibration circuit. In the operations of the circuit, the terminal is arranged to receive an input signal, the output circuit is configured to generate an output signal according to the input signal, the feedback circuit is configured to receive the output signal to generate a current signal to the terminal, and the calibration circuit is configured to generate a control signal to control the feedback circuit to determine a level of the current signal according to the output signal.

Abstract: In a microrunner structure, there are provided with components for a cleaning procedure required to conduct electrochemical sensing when a biosensor is activated for sensing; and a urine signal detection device that is a SoC (System on a Chip), which has a wireless transceiving circuit for receiving a urine measurement method and channel information transmitted from an intelligent device, and in turn, outputting a stimulus signal to trigger a biosensor or a non-biosensor in a multi-channel structure to conduct urine sense processing for a sensing area, as well as transmitting detection processing for a concentration of urine substances from the electrochemical sensing to the intelligent device through the wireless transceiving circuit to assess a risk index between a heart disease or diabetes and a kidney disease.

Abstract: An ear probe assembly comprising a housing structure and a first transducer and a second transducer arranged in said housing structure is disclosed. The ear probe assembly further comprising a channel structure comprising at least a first transducer entrance and a second transducer entrance configured to receive first and second sound ports of the transducers, where further a tip portion is configured to engage with the channel structure in a detachable manner.

Abstract: A blood pressure measurement cuff includes a clamp mechanism that sandwiches a measurement site. The clamp mechanism includes a first clamp portion having a shape that is curved along a first half of the measurement site and a second clamp portion having a shape that is curved along a second half of the measurement site. The slide hole is formed penetrating through one end portion of the first clamp portion. The slide bar extends from the one end portion of the second clamp portion and into the slide hole, fits therein, and slides with friction with respect to the slide hole. The slide hole and the slide bar are curved so as to protrude on a side near other end portions of the first clamp portion and the second clamp portion.

Abstract: The method for administering a plurality of allergens into the skin of a patient uses a multiple test applicator in cooperative engagement with a fluid tray. The applicator has a plurality of scratching barbs each aligned with a plurality of reservoirs in the fluid tray. The method deploys allergen loading followed by allergen deposition. During allergen loading, a different allergen is loaded onto each respective scratching barb from each respective reservoir. Each scratching barb is designed to retain a trace amount of allergen. The applicator fits into one hand of a medical technician administering the skin test. The applicator is removed from the fluid tray and repositioned onto the skin of the patient for allergen deposition. Then, each scratching barb pierces the outer layer of the skin at each respective test site as a trace amount of each respective allergen seeps into each respective test site from each scratching barb.

Abstract: A biopsy device, comprising a flexible coaxial structure, comprising an obturator within a sheath, the obturator being adapted to be displaced with respect to the sheath along the coaxial axis by a force applied at a proximal end; a disruptor, at a distal end of the obturator, adapted to disrupt a tissue surface to free cells therefrom, having a first position covered within the sheath and a second position freely extending beyond the sheath; an element, having a fixed position on the sheath, configured to limit a depth of insertion of the sheath into a cervix.

Abstract: Embodiments of the present invention provide reliable, convenient, and cost-effective methods and apparatuses to determine the hemodynamic status of the patent. The methods and apparatuses provide for the noninvasive determine of hemodynamic status by using systematic perturbations of venous return or trend observation over time. Embodiments do not require invasive pressure monitoring or the use of ventilator but instead can be an entirely noninvasive system.

Abstract: A system and method for monitoring body chemistry of a user, the system comprising: a housing supporting: a microsensor comprising a first and second working electrode, a reference electrode, and a counter electrode, and configured to access interstitial fluid of the user, and an electronics subsystem comprising a signal conditioning module that receives a signal stream, from the microsensor, wherein the electronics subsystem is configured to detect an impedance signal derived from two of the first working electrode, the second working electrode, the reference electrode, and the counter electrode; and a processing subsystem comprising: a first module configured to generate an analysis indicative of an analyte parameter of the user and derived from the signal stream and the impedance signal, and a second module configured to transmit information derived from the analysis to the user, thereby facilitating monitoring of body chemistry of the user.

Abstract: A blood volume monitor includes a carrier mountable on a subject's body part. A measuring arrangement is mounted on the carrier. The measuring arrangement provides data relating to a change in volume of the body part, and outputs signals representative of the change. A control unit is in communication with the measuring arrangement to process data output by the measuring arrangement to determine, using the volume data, the volume of the body part and determines blood volume in the body part. The control unit uses the response signals received from the measuring arrangement and the determined volume of the part of the body to determine the blood volume.

Abstract: A biopsy punch device and method for making punch cuts at consistent predetermined depths. In an exemplary embodiment of the biopsy punch device includes two interconnecting pieces: an inner housing piece and an outer blocking cover piece. The inner housing piece releasably mounts cutting blades arranged in a desired geometric shape for biopsy punch cuts. The blocking cover piece overlays the inner housing piece in an assembled configuration and includes two openings: a larger distal end opening and a narrower proximal end cutting blade opening. The blocking cover distal end opening fits around and adjacent to the housing piece distal end. The blocking cover proximal end opening fits around and adjacent to the cutting blades. With the biopsy punch device in assembled position, the proximal side of the blocking cover piece provides a mechanical stop in the cutting process at the desired depth of penetration of the cutting blades.

Abstract: A method for detecting an artifact of a blood pressure signal includes measuring consecutive signals of blood pressure in real time, dividing the consecutive signals into a plurality of unit waveforms by searching systolic starting points and peak points from the measured signals, determining two outputs by applying N consecutive unit waveforms among the plurality of unit waveforms as an input to a deep belief network (DBN), and determining whether the signal is an artifact or a normal signal by using the two determined outputs. According to the present disclosure, it is possible to minimize various false alarms of bio-signal streams which are measured in real time by automatically eliminating ABP artifacts using a deep belief network (DBN) which is one of deep neural network (DNN) models capable of learning causes and shapes of various types of artifacts together.

Abstract: Indirect, oscillometric, digital blood pressure monitoring systems and methods enabling self-calibration to obtain absolute blood pressure values using algorithmic analysis of arterial pressure pulses to establish an oscillometric profile and compensate for intervening effects on digital arterial pressure. Proper algorithmic analysis is dependent upon proper positioning and maintained engagement of a digital cuff on the digit of a user and subsequent hydraulic coupling of the cuff to the arteries within the digit.

Abstract: A monitoring method is performed by a digital processor while a subject is asleep or with little movement. The method includes receiving transducer signals for a subject and training a model for characteristics of a subject or subject group. The model is used in generating sleep data according to real-time correspondence and values of transducer signals including subject rib displacement, subject abdomen displacement, subject torso movement, and subject orientation. Combinations of the transducer inputs are used to determine features from which outputs such as an AHI score are determined. A feature matrix is normalized based on dynamically-generated positional epochs bordered by subject movements to new positions and used to provide a normalization matrix.

Abstract: An information processing device includes: a processor configured to: acquire time series data relating to at least one of acceleration, amounts of activity of a subject whose sleep is to be evaluated, and body positions of the subject, the time series data being measured by a sensor device that the subject wears; obtain a result of evaluation by analyzing a state of the subject that relates to sleep in each of three sections which are obtained by dividing an evaluation period from a getting-into-bed time point or a first onset-of-sleep time point after getting into bed that is specified by the time-series data until a getting-out-of-bed time point or a last waking time point before getting out of bed; and output the result of evaluation so as to identify that the result corresponds to any one of the three sections.

Abstract: There is provided a biological information monitoring system for monitoring a biological information on a subject on a bed. The system includes a plurality of load detectors which are to be placed in the bed or under legs of the bed, and which are configured to detect a load of the subject; a load separation unit configured to separate a load component which oscillates according to a heartbeat of the subject, from the load of the subject; and a center of gravity position calculation unit configured to obtain a position of a center of gravity of the subject based on the load component which oscillates according to the heartbeat of the subject.

Abstract: A method includes: acquiring body motion data related to body motions of a target person; generating, based on the body motion data, sleep state data related to a sleep state of the target person; storing the sleep state data into a sleep state database; predicting a future change in a physical condition of the target person from the sleep state data by referencing a physical condition prediction information database; and when the physical condition data indicating the physical condition of the target person is acquired, reading past sleep state data over a past period from the sleep state database, collating the physical condition data with the past sleep state data to generate physical condition prediction information for predicting a particular change in the physical condition from particular sleep state data, and registering the physical condition prediction information into the physical condition prediction information database.

Abstract: An apparatus for motion transformation according to an embodiment of the present disclosure includes a basic data input unit through which basic motion data is inputted, a pre-processing unit which acquires a parameter through pre-processing of the inputted basic motion data, a motion transformation unit which performs biomechanical observations-based gait motion transformation processing based on the pre-processed parameter and age input information, and an output unit which outputs the transformation processed motion.

Abstract: A needle system includes a handle, a needle slider partially positioned in the handle, and a needle connected to and extending away from the needle slider. A restrictor is disposed in the needle. The restrictor is configured to inhibit passage of a sample through the needle slider.