Abstract: A registration method and an electronic device for visual navigation in dental implant surgery, comprising obtaining a three-dimensional model of a target tooth to be registered, an entity model of the target tooth and a second model of the target tooth, obtaining a position and attitude matrix of the three-dimensional model in a virtual coordinate system according to the coordinates of at least three points on a three-dimensional model of a substrate after the registration of the three-dimensional model in the virtual coordinate system, mounting the entity model of the target tooth onto a registration standard board, obtaining a position and attitude matrix of the entity model in the visual coordinate system according to three optical marks and the points on the entity model corresponding to the three points, and obtaining a correspondence between the virtual coordinate system and the visual coordinate system according to two position and attitude matrices.

Abstract: A method and system for determining an extent of matter removed from a targeted anatomical structure are disclosed. The method includes acquiring an initial representation of a targeted anatomical structure and then removing matter from the targeted anatomical structure. An instrument is then navigated within the targeted anatomical structure. The instrument includes a tracking array, and a relative position of the instrument within the targeted anatomical structure is determined by the tracking array. The method includes recording the relative position of the instrument within the targeted anatomical structure to determine a final representation of the targeted anatomical structure. Finally, the method includes determining an extent of matter removed from the targeted anatomical structure by comparing the initial representation of the targeted anatomical structure with the final representation of the targeted anatomical structure.

Abstract: The invention relates to a method and apparatus for determining actual points along a positively charged particle beam path and/or vectors of the charged particle beam path, where the determined points and vectors aid tomographic construction of a three-dimensional image of a tumor and surrounding tissue. Further, the determined points and vectors of the positively charged particle beam are used in beam control safety, to modify a tumor treatment plan in real time, and/or in combination with co-gathered X-ray images to form a hybrid proton tomography—X-ray three-dimensional image. Preferably, common elements, such as an injector, accelerator, beam transport system, and/or patient positioning system are used for both tumor treatment and tumor imaging.

Abstract: Methods and systems for performing computer-assisted surgery, including robot-assisted image-guided surgery. Embodiments include marker devices for an image guided surgery system, marker systems and arrays for tracking a robotic arm using a motion tracking system, and image guided surgery methods and systems using optical sensors.

Abstract: A surgical planning and assessment system is disclosed. The system may include a computing system having a processor, a data store, a patient specific planning and analysis module, and a display. The system may be configured to access a database storing a plurality of possible surgical plans. The computing system may store a target surgical plan including a plurality of patient specific inputs including at least one preoperative medical image of a spine of a target patient and analyze the target surgical plan to determine a predicted alignment of the spine of the target patient. The computing system may develop a plurality of predictive models including a predicted alignment of the spine of the target patient based on the target surgical plan and suggest at least one alternative surgical plan with respect to the target surgical plan.

Abstract: An imaging system includes an illuminator for providing illumination on a region of interest, one or more first detectors for detecting reflections of the illumination, and a processing unit. The processing unit is configured to: receive a first image containing the region of interest; determine a first region of high specular reflection in the first image based on the reflections of the illumination on the region of interest; mask the first image by substituting a default color designating masking to alert a user to incomplete image information in the first region of high specular reflection to create a masked first image; and generate a composite image based on the masked first image and a fluorescence image of the region of interest.

Abstract: A surgical planning and assessment system is disclosed. The system may include a computing system having a processor, a data store, and a patient specific planning and analysis module. The system may be configured to store a patient specific target plan including a digital representation of a spinal rod having a target geometry and transform the digital representation into a curved line. The system may generate a spline data set comprising a plurality of spline segments that are sequentially linked to one another. The system may adjust, iteratively, each spline segment until the plurality of spline segments approximate the curved line. The system may generate a digital file comprising drawings for manufacturing a spinal rod based on the plurality of spline segments. In various embodiments, each spline segment may be defined by a corresponding arc or a corresponding line extending between a corresponding starting point and a corresponding ending point.

Abstract: A deep machine-learning approach is used for medical image fusion by a medical imaging system. This one approach may be used for different applications. For a given application, the same deep learning is used but with different application-specific training data. The resulting deep-learnt classifier provides a reduced feature vector in response to input of intensities of one image and displacement vectors for patches of the one image relative to another image. The output feature vector is used to determine the deformation for medical image fusion.

Abstract: A system for imaging a robotically moved medical object has a movement device for robotic movement of the medical object, a medical imaging device, and a processing unit. The processing unit is configured to receive a data set that maps a vessel structure of an examination object and is registered with the medical imaging device, and to determine an object path along the vessel structure toward a target region in the data set. The movement device is configured to move the medical object along the object path and provide an object parameter relating to a movement state of the medical object. The processing unit is further configured to control a positioning of the medical imaging device relative to the examination object as a function of object parameter and object path such that a predefined section of the medical object is mapped in image data acquired by the medical imaging device.

Abstract: A body mountable robot may include a set of stages disposed in a parallel configuration. The body mountable robot may include a set of actuating joints, wherein an actuating joint, of the set of actuating joints, is configured to rotate with respect to a corresponding stage of the set of stages. The body mountable robot may include at least one actuator, wherein the at least one actuator is configured to actuate at least one actuating joint of the set of actuating joints. The body mountable robot may include a set of scissor mechanisms, wherein a scissor mechanism, of the set of scissor mechanisms, that is coupled to the actuating joint, is supported by the corresponding stage, and wherein the scissor mechanism is configured to translate with respect to the corresponding stage.

Abstract: The present disclosure relates to extraction of probe motion estimates from acquired ultrasound image frames. Such image-extracted probe motion data can be used alone or in combination with sensed motion data, such as acquired using an inertial measurement unit (IMU). In certain implementations, the image-extracted probe motion can be used to provide or maintain anatomic context in a sequence of images or to provide guidance to a user.

Abstract: Devices, systems, and methods for a robot-assisted surgery. Navigable instrumentation, which are capable of being navigated by a surgeon using the surgical robot system, and navigation software allow for the navigated placement of interbody fusion devices or other surgical devices.

Abstract: A method for diagnosing, validation of diagnosis and treating a patient having lesions in both arteries of left and right lower limbs. By determining that a larger vessel diameter lesion to be treated first, catheters and an operation time can be reduced is to be treated first on a priority basis based on diagnostic data, deciding that a smaller vessel diameter lesion is to be treated next, then treating the lesions substantially continuously.

Abstract: Examples described herein may predict therapy efficacy and/or therapeutic parameters using a comparison of individual patient status data and brain network response maps for the therapy. For example, VNS parameters may be predicted using a comparison of patient EEG data and brain network response maps of VNS therapy at various parameters.

Abstract: Devices, Systems, and Methods for detecting a 3-dimensional position of an object, and surgical automation involving the same. The surgical robot system may include a robot having a robot base, a robot arm coupled to the robot base, and an end-effector coupled to the robot arm. The end-effector, surgical instruments, the patient, and/or other objects to be tracked include active and/or passive tracking markers. Cameras, such as stereophotogrammetric infrared cameras, are able to detect the tracking markers, and the robot determines a 3-dimensional position of the object from the tracking markers.

Abstract: Ultrasound image devices, systems, and methods are provided. In one embodiment, an ultrasound imaging system includes an interface coupled to an ultrasound imaging component and configured to receive a plurality of image data frames representative of a subject's body including at least a portion of a lung; a processing component in communication with the interface and configured to determine a metric for each image data frame of the plurality of image data frames based on a threshold comparison; and determine a dynamic air bronchogram (AB) condition of the subject's body based on a variation across the metrics of the plurality of image data frames. In one embodiment, the processing component is configured to determine differential data frames based on differences across consecutive image data frames of the plurality of image data frames; and determine a dynamic AB condition of the subject's body based on the differential data frames.

Abstract: Systems and methods are provided for identifying and locating a plurality of reflector markers implanted within a target tissue region within a patient's body. A probe is provided that is activated to transmit electromagnetic signals into the patient's body, receive reflected signals from the patient's body, and in synchronization with transmitting the electromagnetic signals, deliver light pulses into the patient's body. The markers reflector tags modulate reflected signals from the respective markers based on orthogonal code sequences opening and closing respective switches of the markers to modulate the reflective properties of the markers. The probe processes the return signals to separate the reflected signals based at least in part on the code sequences to identify and locate each of the plurality of reflector tags substantially simultaneously.

Abstract: A diagnostic imaging device includes a probe that uses both an ultrasound transducer and frequency-domain diffuse optical imaging (FD-DOI) to assist with locating and diagnosing sub-tissue anomalies. According to one aspect, the diagnostic imaging device relates to a clip-on cap that can be utilized with existing ultrasound transducers. The diagnostic imaging device described herein can be utilized for image-guided needle biopsy to regions where prostate tissues are highly suspicious for high-grade cancer, as well as for image guided interventions, such as cryotherapy, photodynamic therapy, and brachytherapy for early-stage or localized prostate cancer.

Abstract: The subject matter of the present disclosure generally relates to techniques for following a treatment protocol having one or more treatment parameters to cause a targeted physiological outcome at a distal site, assessing an expression level of a gene in a region of interest after completing the treatment protocol, and modifying the one or more treatment parameters based on the expression level of the gene. The treatment protocol may include one or more ultrasound energy treatments to the region of interest.

Abstract: A system for detecting/quantifying the conductance of a right-to-left cardiac shunt includes a mouthpiece assembly, a solenoid-driven vacuum/pressurization assembly; a controller for operating the solenoid-driven vacuum/pressurization assembly; and a monitor for displaying the instructions from the controller. A microbubble counting cell and digital image sensor are combined with software-based image analysis to determine a number of microbubbles contained in a microbubble counting zone. A monitor enables operator specification of total volume of contrast agent to be injected into the patient. One or more first Doppler ultrasound transducer arrays are positioned adjacent to targeted intracranial arteries at one side of the skull or a pair of first Doppler ultrasound transducer arrays positioned adjacent to targeted intracranial arteries at both sides of the skull.