Patents Examined by Charesse L. Evans
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Patent number: 6372266Abstract: A medicinal composition for treating dysmenorrhea and endometriosis comprising a plant extract and containing proanthocyanidins as an effective component thereof. The composition is provided and administered in the form of soft capsules, tablets, or a powdery or liquid preparation to be used for treating dysmenorrhea and endometriosis.Type: GrantFiled: May 19, 2000Date of Patent: April 16, 2002Assignees: Tradepia Co. Ltd., Horphag Research LimitedInventors: Nobutaka Suzuki, Takafumi Kohama
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Patent number: 6368623Abstract: The invention relates to a pulverulent corn-steep without a drying substrate, said corn-steep containing lactic acid. It also relates to a method of obtaining this pulverulent corn-steep as well as to its use in the fermentation industry.Type: GrantFiled: April 4, 2000Date of Patent: April 9, 2002Assignee: Roquette FreresInventors: Thomas Erpicum, Marie-Hélène Saniez
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Patent number: 6365176Abstract: Described herein is a nutritional supplement to be incorporated into the diet of a type 2 diabetic or an individual having lipodystrophy. The supplement provides active food-grade ingredients to improve the management of blood glucose and blood lipid levels. The supplement additionally aids in the improvement of the effects of platelet aggregation. The supplement should be taken daily during or at the end of the two largest meals, where most of the fat and cholesterol are likely to be ingested.Type: GrantFiled: September 18, 2000Date of Patent: April 2, 2002Assignee: Functional Foods, Inc.Inventors: Stacey J. Bell, Judith Shabert
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Patent number: 6358533Abstract: A microcrystalline cellulose-based excipient having improved compressibility, whether utilized in direct compression, dry granulation or wet granulation formulations, is disclosed. The excipient is an agglomerate of microcrystalline cellulose particles and from about 0.1% to about 20% silicon dioxide particles, by weight of the microcrystalline cellulose, wherein the microcrystalline cellulose and silicon dioxide are in intimate association with each other. The silicon dioxide utilized in the novel excipient has a particle size from about 1 nanometer to about 100 microns. Most preferably, the silicon dioxide is a grade of colloidal silicon dioxide.Type: GrantFiled: January 4, 2001Date of Patent: March 19, 2002Assignee: Edward Mendell, Co., Inc.Inventors: Bob E. Sherwood, John H. Staniforth, Edward A. Hunter
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Patent number: 6352687Abstract: A transparent nail enamel composition includes small pieces of light-reflecting decorative material in the nature of glitters, micas and/or other large-sized particles. The glitter is suspended in the nail enamel composition using fumed silica. The nail enamel composition exhibits both transparent wet and dry state clarity.Type: GrantFiled: July 26, 1999Date of Patent: March 5, 2002Assignee: Kirker Enterprises, Inc.Inventors: Anatoly Ismailer, Robert L. Socci
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Patent number: 6346264Abstract: A nutritional supplement for ingestion by humans for restoring growth hormone levels consisting of branched chain amino acids chosen from the group leucine, isoleucine, and valine; and free form amino acids chosen from the group lysine, glutamine, ornithine, arginine, and glycine.Type: GrantFiled: April 27, 2000Date of Patent: February 12, 2002Assignee: International Health Products and Services Ltd.Inventor: Philip White
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Physiological combination of active substances to enhance the skin's defenses against noxious agents
Patent number: 6346258Abstract: The present invention relates to a combination of active substances for enhancing the skin's defense against chemical and physical irritations, for example, from job-related stress, strain on the skin from leisure activities (bathing, showering, sun exposure, household chemicals, building materials, etc.) and from the working environment. The topical agent comprises ionically bound and/or free thiocyanate ions and urea in addition to per se known auxiliary agents and carriers.Type: GrantFiled: December 13, 1999Date of Patent: February 12, 2002Inventor: Axel Kramer -
Patent number: 6344188Abstract: A wrinkle reducing cream is presented which reduces wrinkles upon topical application to the skin. The main ingredients of the composition include a water and caffeine composition which is mixed together in a first vessel and a glycerin composition heated in a second vessel. The three components of the active ingredient are mixed carefully, making sure that any precipitate produced is remixed into the solution. After heating and mixing the components, the entire composition is cooled with care being taken to push any precipitate back into solution to ensure an even distribution of all of the components. The active ingredient thus produced may be combined with a suitable cosmetic vehicle to provide the topical wrinkle reducing composition. The composition is topically applied to the wrinkled area over a period of days or months in order to reduce or entirely eliminate wrinkles from the skin. The final active ingredient may also be used for other applications.Type: GrantFiled: March 1, 2000Date of Patent: February 5, 2002Assignee: Victor Silva, Inc.Inventors: Victor Silva, Bryan K. Harris, Gregory J. Rudroff, Andrew W. Szczesiul
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Patent number: 6340470Abstract: A soluble isoflavone composition comprises isoflavone and a solubilizing agent consisting of anhydrous or water-containing propylene glycol and/or octenyl succinate-treated starch. The soluble isoflavone composition is prepared by, for instance, a method which comprises the step of heating isoflavone and a solubilizing agent consisting of anhydrous or water-containing propylene glycol and/or octenyl succinate-treated starch in the presence of water to thus solubilize isoflavone in water. The soluble isoflavone composition of the present invention has high solubility in water, is easily dissolved in water and is stable over a long period of time.Type: GrantFiled: December 29, 1999Date of Patent: January 22, 2002Assignee: Matsutani Chemical Industries Co., Ltd.Inventor: Koji Tsukuda
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Patent number: 6333045Abstract: There is provided an aqueous liquid pharmaceutical composition which comprises Gatifloxacin (chemical nomenclature: (±)-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinoline carboxylic acid) or its salt and disodium edetate. Further, there are provided a method for raising corneal permeability of Gatifloxacin, a method for preventing precipitation of Gatifloxacin crystals, and a method for preventing coloration of Gatifloxacin by incorporating disodium edetate into an aqueous liquid preparation containing Gatifloxacin or its salt.Type: GrantFiled: April 21, 2000Date of Patent: December 25, 2001Assignees: Senju Pharmaceutical Co., Ltd., Kyorin Pharmaceutical Co., Ltd.Inventors: Shinichi Yasueda, Katsuhiro Inada
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Patent number: 6309665Abstract: The invention concerns a composition comprising a microemulsion forming system by contact with a hydrophilic phase brought, after ingestion, by the physiological fluid, said microemulsion forming system comprising: at least an active principle; a lipophilic phase; a surfactant (TA); a co-surfactant (CoTA). The invention is characterized in that said composition further comprises an inert polymeric matrix which cannot be ionised at physiological pH, dispersed in the microemulsion forming system before ingestion, said polymeric matrix being capable, after ingestion, of forming on contacting the physiological fluid, a gelled polymeric matrix enabling to release by diffusion, in continuous and prolonged manner the already micro-emulsified active principle.Type: GrantFiled: February 2, 2001Date of Patent: October 30, 2001Assignee: Gattefosse S.A.Inventors: Philippe Barthelemy, Hassan Benameur
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Patent number: 6306412Abstract: An adhesive cosmetic strip is provided which includes a flexible water-insoluble substrate, an adhesive composition deposited onto the substrate and an agent interactive with water present in a sufficient quantity to induce a change of temperature of the strip. When applied to the skin, the strip is warmed by a reaction between water and an exothermic or endothermic agent held within the strip. Moisture within the skin or externally applied water penetrates the strip and will react with the agent to cause an increase or decrease in temperature.Type: GrantFiled: May 1, 2000Date of Patent: October 23, 2001Assignee: Unilever Home & Personal Care USA, Division of Conopco, Inc.Inventors: Brian Andrew Crotty, Craig Stephen Slavtcheff, Alexander Paul Znaiden
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Patent number: 6296840Abstract: A colored facial masque is formed from a paste which is produced by mixing a dry powder masque component. The dry powder masque component includes a first water soluble colorant and said liquid masque component includes a second water soluble colorant, the colors of said first and second water soluble colorants differing from the color of the facial masque.Type: GrantFiled: August 2, 2000Date of Patent: October 2, 2001Assignee: Rodan & Fields, LLCInventors: Kathryn P. Rodan, Kathy A. Fields, Kenneth Klein, David Garlen
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Patent number: 6290980Abstract: A method and packaging for vaccinating or medicating an animal by implanting a solid dose medicament in an animal. The solid dose medicament, or plurality of such medicaments, are each color-coded to identify a particular active ingredient, then packaged in a pellet magazine through which the doses are visible, and thereafter the pellets are implanted, usually subcutaneously, into the base of the ear or in the neck of an animal. The same system can be used for colored ballistic implants.Type: GrantFiled: April 28, 2000Date of Patent: September 18, 2001Assignee: Solidose, LLCInventor: Richard D. Hansen
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Patent number: 6287582Abstract: A disposable towelette product is provided which includes a flexible water-insoluble substrate such as a tissue impregnated with an alpha- or beta-hydroxycarboxylic acid in a cosmetically acceptable carrier vehicle. Impregnated cosmetic composition in water will have a pH no higher than 6.8. A silicone microemulsion is present to minimize any stickiness resulting from deposition of the hydroxycarboxylic acid by the towelette onto the skin. In the presence of fatty acid group containing surfactants, the silicone microemulsion controls foul odors that the surfactants may emit through hydrolysis at low pH.Type: GrantFiled: May 1, 2000Date of Patent: September 11, 2001Assignee: Unilever Home & Personal Care USA, division of Conopco, Inc.Inventors: Robert Edward Gott, Craig Stephen Slavtcheff, Alexander Paul Znaiden
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Patent number: 6287580Abstract: A self-warming cosmetic composition is provided which delivers skin conditioning agents and is based upon a redox system of iron powder and a catalyst such as charcoal to provide the warmth. The system is activated with moisture and air.Type: GrantFiled: April 26, 2000Date of Patent: September 11, 2001Assignee: Unilever Home & Personal Care USA, a division of Conopco, Inc.Inventors: Robert Edward Gott, Craig Stephen Slavtcheff, Alexander Paul Znaiden, Brian Andrew Crotty
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Patent number: 6287553Abstract: A topical composition and cosmetic method for treating skin conditions selected form the group consisting of wrinkling, sagging, photodamaged skin, sensitive skin, dry skin, flaky skin, red skin, irritated skin, itchy skin and age spots, the composition comprising: (a) conjugated linoleic acid, and/or derivatives thereof comprising conjugated linoleic acid moieties, in which at least 50% by weight of the conjugated linoleic acid and/or moieties, is present as the cis 9 trans 11 isomer; and (b) a dermatologically acceptable carrier.Type: GrantFiled: December 13, 1999Date of Patent: September 11, 2001Assignee: Unilever Home & Personal Care USA, division of Conopco, Inc.Inventors: Simon Alaluf, Martin Richard Green, Clive Roderick Harding, Heng-Long Hu, Gerald Patrick McNeill, Jonathan Richard Powell, Anthony Vincent Rawlings, Julia Sarah Rogers, Allan Watkinson
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Patent number: 6274150Abstract: The present invention provides a nanoemulsion, that includes: an oily phase dispersed in an aqueous phase; and at least one anionic surfactant selected from the group including phosphoric acid fatty esters and oxyethylenated derivatives thereof, and mixtures thereof; wherein the oily phase includes oil globules having a number-average size of less than 100 nm; wherein the oily phase includes at least one oil having a molecular weight of greater than 400; and wherein a weight ratio of the oily phase to the surfactant ranges from 2 to 10. The invention also provides a process for making the nanoemulsion, and methods for its use. The nanoemulsion is ideally transparent and stable on storage. It can ideally contain large amounts of oil while retaining good transparency and good cosmetic properties. The nanoemulsion is particularly useful in compositions, including topical, pharmaceutical, dermatological, cosmetic, opthalmic, and opthalmologic.Type: GrantFiled: December 21, 1999Date of Patent: August 14, 2001Assignee: L'OrealInventors: Jean-Thierry Simonnet, Odile Sonneville, Sylvie Legret
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Patent number: 6270783Abstract: An adhesive cosmetic strip is provided which includes a flexible water-insoluble substrate, an adhesive composition deposited onto the substrate, a liquid crystal thermochromic substance, and an agent interactive with water to ensure a temperature rise of at least 2° C. in the strip. The thermochromic substance may be impregnated into the substrate or dispersed within the adhesive composition. When applied to the skin, the strip is warmed by a reaction between water and an exothermic or endothermic agent held within the strip. Moisture within the skin or externally applied water penetrates the strip and will react with the agent to cause an increase in temperature. Subsequently this increase in temperature will induce a color change in the thermochromic substance.Type: GrantFiled: April 26, 2000Date of Patent: August 7, 2001Assignee: Unilever Home & Personal Care USA, division of Conopco, Inc.Inventors: Craig Stephen Slavtcheff, Alexander Paul Znaiden, Michael Indursky, Brian Andrew Crotty
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Patent number: 6245346Abstract: Pharmaceutical composition for the controlled release of at least one water-insoluble active principle, containing a homopolymer of D,L-lactic acid or of L-lactic acid of low molecular weight combined with said active principle, wherein the molecular weight of the homopolymer of D,L-lactic acid is between approximately 2,000 and 6,000 daltons or the molecular weight of the homopolymer of L-lactic acid is about 4,000 daltons.Type: GrantFiled: January 6, 1999Date of Patent: June 12, 2001Assignee: Debio Recherche Pharmaceutique S.A.Inventors: Alexandra Rothen-Weinhold, Robert Gurny, Piero Orsolini, Frédéric Heimgartner