Abstract: Systems and methods utilize continuous flow plasma ionization to process and analyze the contents of a medical fluid sample, including blood and other bodily fluids and gases. Advantageously, the systems and methods are capable of automatically identifying all or nearly all chemical components of the medical fluid sample in real time, allowing for quicker and improved diagnostic capabilities.

Abstract: The present invention provides methods, systems and kits for performing microwell analysis in sealed small volumes. The microwells of the invention are sealed through the pairing of microwell and bead geometry wherein the diameter of the beads is greater than the diameter of the bottom of the microwells. Loading the beads into the microwells seals samples within an analytical space between the bottom of a nested bead and the bottom of the subject microwell.

Abstract: A sample analysis system, method and a cell image analysis device. The sample analysis system includes a blood cell analyzer, a smear preparation apparatus, a cell image analysis apparatus, and a controller. The controller obtains a test result of at least one sample from the blood cell analyzer. When one sample needs to be analyzed by the cell image analysis device, the controller can further control an imaging condition used by the cell image analysis device according to a value of at least one type of cells in the test result of the sample, such that the cell image analysis device can automatically selects an imaging condition matching the test result for imaging according to different test results of the sample. Therefore, a matching imaging condition is used to specifically capture and analyze cell images of a smear of the sample, thereby improving processing efficiency and accuracy.

Abstract: Assembly for handbag multiple straws for packaging animal semen, each having a predetermined diameter and a predetermined length, comprising a freezing ramp (4) that has a rim and a bottom surrounding a central free space (5), said bottom comprising two toothed walls (11, 25) which extend longitudinally along said central free space (5), each toothed lied wall (11, 25) having a toothing at its top, the toothings of said toothed walls (11, 25) being identical, with each trough being delimited by a surface having a curvature along said predetermined diameter, characterized in that it further comprises a crosspiece (100) comprising parts (103, 104) that are able to move with respect to one another and are configured to permit a position in which said crosspiece (100) is removably joined to said freezing ramp (4) at a location provided to receive at least one said straw (1).

Abstract: A specimen holder includes a stick and an RFID tag. The stick is elongate along a longitudinal direction, and has a distal end and a proximal end opposite the distal end with respect to the longitudinal direction. The stick includes an outer surface and a distal portion of the outer surface that is closer to the distal end than the proximal end. The stick further includes an internal cavity that extends from a first terminal end to a second terminal end. The stick includes a midplane that is normal to the longitudinal direction, and the midplane is located equidistant between the distal end and the proximal end. The first terminal end, the second terminal end and an entirety of the internal cavity are all located between the midplane and the proximal end. The RFID tag is positioned within the internal cavity.

Abstract: Velvet disease infestation is detected using affinity reagents that are cross-reactive with one or more A. ocellatum or P. pillulare antigens. The analysis may be performed shipboard, dockside, in an aquaculture or aquarium setting, otherwise in situ at the point of sample collection or elsewhere. The results may be used to monitor health and disease of captured or cultured fish species or the safety of water to be introduced into an aquaculture facility.

Abstract: A rack for holding a plurality of petri-dishes, containing a plate-like main body with a plurality of adjacent and spaced apart holding portions each configured to receive and support, in a substantially horizontal orientation that is substantially perpendicular to a plane of the plate-like main body, a petri-dish, wherein each holding portion includes positioning features for positioning the petri-dish in the holding portion.

Abstract: An application apparatus includes: an application needle that applies, to a target, an application material having its viscosity changing under shear; a drive unit that moves the application needle up and down; and a controller that controls the drive unit to move the application needle such that shear is applied to the application material at a shear speed depending on a type of the application material and depending on a target application amount or a target application diameter.

Abstract: A biosensor diagnostic device can include an interface configured to receive an electrical signal from a biosensor cartridge in response to being connected to a connection terminal of the biosensor cartridge; an image reader configured to capture a code image on the biosensor cartridge. And a signal processor configured to process a signal received from the interface for generating diagnostic result information. Also, the biosensor diagnostic device can include a wireless transceiver configured to transmit information corresponding to the code image and the diagnostic result information to a server or an external terminal.

Abstract: A reaction vessel comprises a lower chamber with a first volume, and an upper chamber with a second volume greater than the first volume. A thermocycling system for heating the reaction vessel includes a lower heating zone to heat the lower chamber, an upper heating zone to heat the upper chamber, and a lid heater to heat an opening of the upper chamber. A method comprises loading a sample into a lower chamber of a reaction vessel, thermocycling the lower chamber using a lower heating zone of the thermo cycler, combining an additive into the sample to produce a combination filling the lower chamber and at least partially filling an upper chamber of the reaction vessel, and incubating the upper and lower chambers using the lower heating zone and an upper heating zone. The lower and upper chambers can have different wall thicknesses to facilitate heat transfer.

Abstract: A support element for a plurality of packaging straws, the support element comprising a plate (31) and two flanges (37) rigidly connected to said plate (31) and comprising a fluted surface (53) having a plurality of similar grooves (36), each flange (37) comprising a central part as well as a first projecting part (42) and a second projecting part (43), each extending from one side of the central part, characterised in that the first projecting part comprises a bracket (42) having a bearing face and the second projecting part comprises another bracket (43) having another bearing face, said bearing face and said other bearing face being upwards facing and, in the direction of height, said bearing face being further from said plate (31) than said other bearing face. The assembly comprises the support element and a freezing rack (4).

Abstract: Magnetic levitation particle separation systems and methods for use with multi-channel flow cells. The system may include a core for receiving and holding the flow cell, with upper and lower clamps for securing the flow cell and positioning it relative to an array of magnets. The system is configured to image particle separation in processing channels of the flow cell, and to regulate the flow cell's temperature. The core may be removable as a single unit, facilitating reconfiguration of the system.

Abstract: A carrier for holding a biological sample includes a substrate. The substrate is configured to engage a first sample chamber comprising a first opening characterized by a first opening diameter or a second sample chamber comprising a second opening characterized by a second opening diameter that is greater than the first opening diameter. The substrate includes an upper portion, a lower portion, and an intermediate portion disposed between the upper portion and the lower portion. The lower portion is disposed below the upper portion and comprises a bottom surface configured to receive a biological sample. The intermediate portion is characterized by a first substrate diameter and the lower portion is characterized by a second substrate diameter that is less than the first substrate diameter.

Abstract: An object of the present invention is to provide a reagent kit, a measurement kit, and a measurement method for measuring serum amyloid A, which enable simple and rapid measurement of serum amyloid A by promoting dissociation of the serum amyloid A from HDL and carrying out an antigen-antibody reaction. According to the present invention, provided is a reagent kit for measuring serum amyloid A, including first particles having a label and modified with a first binding substance having a property of specifically binding to serum amyloid A, at least one nonionic surfactant having an HLB value of 17 to 20, which is defined by (inorganicity value/organicity value)×10, and a molecular weight of 1000 or less, and a buffer capable of adjusting a pH of a reaction solution to be in a range of 5.5 to 7.0 or a range of 8.5 to 9.0.

Abstract: A flow cell of the flow cytometer of the present invention includes: a sample flow path through which a sample fluid containing a sample flows; and a sample fluid supply portion which communicates with an upstream end of the sample flow path in the sample fluid flow direction and supplies the sample fluid to the sample flow path, wherein the sample fluid supply portion includes a plurality of sample opening portions which supply a sample fluid to the sample flow path, a cleaning liquid supply opening portion to which a second tube is connectable and which supplies a cleaning liquid for cleaning the sample fluid supply portion, and a cleaning liquid discharge opening portion to which a first tube is connectable and which discharges the cleaning liquid from the sample fluid supply portion.

Abstract: The disclosure provides example devices and methods for making and using the devices for rapid testing for the SARS-CoV-2 virus. The example device includes (a) a substrate coupled to a metal oxide layer, (b) a graphene layer coupled to the metal oxide layer, (c) a chemical or biochemical linker functionalized with the graphene layer, and (d) a plurality of SARS-CoV-2 receptors that are bound to the graphene layer via the chemical or biochemical linker, wherein the plurality of SARS-CoV-2 receptors comprise SARS-CoV-2 spike antibodies or SARS-CoV-2 spike proteins, where the graphene layer is configured to have a first phononic energy, when the plurality of SARS-CoV-2 receptors are unattached to target molecules, and a second phononic energy, when the plurality of SARS-CoV-2 receptors are attached to target molecules.

Abstract: The present invention relates to the field of biomedical technology and discloses a cartridge and a testing device. The cartridge comprises a sample lysis compartment, a first sample mixing compartment and a first PCR compartment; a first valve is disposed between the sample lysis compartment and the first sample mixing compartment, the first valve controls the flowing or blocking of the sample between the sample lysis compartment and the first sample mixing compartment; a fourth valve is disposed between the first PCR compartment and the first sample mixing compartment, the fourth valve controls the flow or blocking of the sample between the first sample mixing compartment and the first PCR compartment; a first reagent is provided in the first sample mixing compartment. In the compartment, nucleic acids in the sample mix with the first reagent and is then sent to the first PCR compartment for amplification.

Abstract: A processor assembly including: an exposure station operable to expose a sample on a slide; a print station operable to apply a reagent to the exposed sample through a thermal inkjet process; and a robotic transfer mechanism to transfer the slide from the exposure station to the print station. Also, a reagent cartridge including: a body defining a container having a volume therein; a nonmetallic bag in the container operable to contain a reagent; and a printhead at a base of the body, the printhead coupled to an outlet of the bag. Further, a method including exposing a sample on a slide in a processor assembly; robotically transferring the slide to a printing station of the processor assembly; and applying a reagent to the exposed sample at the printing station by a thermal inkjet printing process.

Abstract: Provided are electronic biosensors based on graphene field effect transistors that utilize engineered hairpin probe DNA that allows for target recycling and hybridization chain reactions.

Abstract: Disclosed are apparatuses, systems, and methods for processing materials, including biological or chemical materials. A manufacturing module may include a work station configured to perform a process involving equipment capable of use with biological or chemical material, a first transportation segment that is configured to connect and disconnect with a second transportation segment such that when connected, a carrier of the biological or chemical material can be transported from the first transportation segment to the second transportation segment, a pick and place robot configured to move an element between the first transportation segment and the work station; and a movement mechanism configured to allow the work station, the first transportation segment, and the pick and place robot to be moved as a single unit. A system may include a plurality of manufacturing modules that are reconfigurable to a plurality of configurations.